DeborahWenkertMD

PubMed

• Pyridoxine challenge reflects pediatric hypophosphatasia severity and thereby examines tissue-nonspecific alkaline phosphatase's role in vitamin Bmetabolism.
  Michael P Whyte, Fan Zhang, Karen E Mack, Deborah Wenkert, Gary S Gottesman
  Bone. 2024-04-01
• Effects of food, fasting, and exercise on plasma pyrophosphate levels and ENPP1 activity in healthy adults.
  Gus Khursigara, Pedro Huertas, Deborah Wenkert, Kevin O'Brien, Yves Sabbagh
  Bone. 2023-06-01
• 12 citations
  Why are not There More Bayesian Clinical Trials? Perceived Barriers and Educational Preferences Among Medical Researchers Involved in Drug Development.
  , Jennifer Clark, Natalia Muhlemann, Fanni Natanegara, Andrew Hartley
  Therapeutic Innovation & Regulatory Science. 2023-05-01

Journal Articles

• Why are not There More Bayesian Clinical Trials? Perceived Barriers and Educational Preferences Among Medical Researchers Involved in Drug Development.  
  Clark J, Muhlemann N, Natanegara F, Hartley A, Wenkert D, Wang F, Harrell FE Jr, Bray R., Ther Innov Regul Sci., 1/3/2022
• Hypophosphatasia: Natural history study of 101 affected children investigated at one research center  
  Whyte MP, Wenkert D, Zhang F, Bone, 1/1/2016
• Auricular Ossification: A Newly Recognized Feature of Osteoprotegerin-Deficiency Juvenile Paget Disease  
  Gottesman GS, Madson KL, McAlister WH, Nenninger AR, Wenkert D, Mumm S, Whyte MP, Am J Med Genetics, 1/1/2016
• Herpes Zoster Reactivation in Patients With Rheumatoid Arthritis: Analysis of Disease Characteristics and Disease-Modifying Antirheumatic Drugs  
  Pappas DA, Hooper MM, Kremer JM, Reed G, Shan Y, Wenkert D, Greenberg JD, Curtis JR, Arthritis Care Res, 1/1/2015
• Hypophosphatasia: Validation and expansion of the clinical nosology for children from 25 years experience with 173 pediatric patients  
  Whyte MP, Zhang F, Wenkert D, McAlister WH, Mack KE, Benigno MC, Coburn SP, Wagy S, Griffin DM, Ericson KL, Mumm S, Bone, 1/1/2015
• Multicentric carpotarsal osteolysis syndrome is caused by only a few domain-specific mutations in MAFB, a negative regulator of RANKL-induced osteoclastogenesis  
  Mumm S, Huskey M, Duan S, Wenkert D, Madson KL, Gottesman GS, Nenninger AR, Laxer RM, McAlister WH, Whyte MP, Am J Med Genet A, 1/1/2014
• Malignancies in children and young adults on etanercept: summary of cases from clinical trials and postmarketing reports  
  Hooper M, Wenkert D, Bitman B, Dias VC, Bartley Y, Pediatr Rheumatol Online J, 1/1/2013
• Pregnancy-associated osteoporosis with a heterozygous deactivating LDL receptor-related protein 5 (LRP5) mutation and a homozygous methylenetetrahydrofolate reductase ...  
  Cook FJ, Mumm S, Whyte MP, Wenkert D, J Bone Miner, 1/1/2013
• Rheumatoid Arthritis Disease Activity and Disability Affect the Risk of Serious Infection Events in RADIUS 1  
  Weaver A, Troum O, Hooper M, Koenig AS, Chaudhari S, Feng J, Wenkert D, J Rheumatol, 1/1/2013
• A randomized study to evaluate the efficacy and safety of adding topical therapy to etanercept in patients with moderate to severe plaque psoriasis  
  Lebwohl MG, Kircik L, Callis Duffin K, Pariser D, Hooper M, Wenkert D, Thompson EH, Yang J, Kricorian G, Koo J, J Am Acad Dermatol, 1/1/2013
• Hypophosphatasia (HPP): Enzyme Replacement Therapy (EzRT) for Children Using Bone-Targeted, Tissue-Nonspecific Alkaline Phosphatase  
  Whyte MP, Greenberg CR, Salman NJ, Bober M, McAlister WH, Wenkert D et al, N Engl J Med, 1/1/2012
• Dual-Energy X-Ray Absorptiometry Interpretation: A Simple Equation for Height Correction in Preteenage Children  
  Zhang F, Whyte MP, Wenkert D, J Clin Densitom, 1/1/2012
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  Whyte MP, Wenkert D, Demertzis JL, Dicarlo EF, Westenberg E, Mumm S, J Bone Miner Res, 1/1/2012
• Camurati-Engelmann disease: Unique variant featuring a novel mutation in TGFBeta1 encoding transforming growth factor beta 1 and a missense change in TNFSF11 encoding ...  
  Whyte MP, Totty WG, Novack DV, Zhang X, Wenkert D, Mumm S, J Bone Miner Res, 1/1/2011
• Chronic recurrent multifocal osteomyelitis mimicked in childhood hypophosphatasia  
  Whyte MP, Wenkert D, McAlister WH, Mughal MZ, Freemont AJ, Whitehouse R,Baildam EM, Coburn SP, Ryan LM, Mumm S, J Bone Miner Res, 1/1/2009
• Absence of MMP2 mutation in idiopathic multicentric osteolysis with nephropathy  
  Wenkert D, Mumm S, Wiegand SM, McAlister WH, Whyte MP, Clinical Orthopedics and Related Research, 1/1/2007
• Infantile hypophosphatasia: transplantation therapy trial using bone fragments and cultured osteoblasts  
  Cahill, R, Wenkert D, Perlman SA, Steele A, Coburn SP, McAlister WH, Mumm S, Whyte MP, Journal of Clinical Endocrinology and Metabolism, 1/1/2007
• Skeletal changes in epidermal nevus syndrome: does focal bone disease harbor clues concerning pathogenesis?  
  Heike CL, Cunningham ML, Steiner RD, Wenkert D, Hornung RL, Gruss JS, Gannon FH, McAlister WH, Mumm S, Whyte MP, American Journal of Medical Genetics, 1/1/2005
• Bisphosphonates in children with bone diseases (Reply Letter)  
  Whyte MP, Wenkert D, McAlister WH, Mumm S, New England Journal of Medicine, 1/1/2003
• Bisphosphonate-induced osteopetrosis  
  Whyte MP, Wenkert D, Clements KL, McAlister WH, Mumm S, New England Journal of Medicine, 1/1/2003
• Modulation of linker histones during development in tetrahymena: selective elimination of linker histones during the differentiation of mew macronuclei  
  Chicoine LC, Wenkert D, Richmond R, Wiggins JC, Allis CD, Dev Biol, 1/1/1985
• Timing of the appearance of macronuclear specific histone variant hvl and gene expression in developing new macronuclei of tetrahymena thermophia  
  Wenkert D, Allis CD, J Cell Biol, 1/1/1984
• Lipoprotein (a) purification problems and structural properties  
  Morrisett, JD, Wenkert D, Gotto AM, Dahlen GH, Gianturco SH, Heideman C, Gaubatz JW, Proceedings of the Workshop on Apolipoprotein Quantifications, 1/1/1983
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Books/Book Chapters

• Textbook of Pediatric Rheumatology 
  Chapter: Primary Disorders of Bone and Connective Tissue 
  Page 742 - 765Wenkert DEditors: J Cassidy, R Petty, R Laxer, and C Lindsley.Elsevier2011
• Bone Disease in Rheumatology 
  Chapter: Heterotopic Ossification and Calcinosis 
  Page 197 - 202Wenkert D, Whyte MPEditors: MJ Maricic and O Gluck.Lippincott, Williams & Wilkins, Philadelphia, PA2005