DeanA.TroyerMD

PubMed

• 121 citations
  In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine
  Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe
  Proteomics. 2013-05-01
• 104 citations
  The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers.
  Merav Darash-Yahana, John W. Gillespie, Stephen M. Hewitt, Yun-Yun K. Chen, Shin Maeda
  Plos One. 2009-08-19
• 175 citations
  MALDI imaging mass spectrometry profiling of N-glycans in formalin-fixed paraffin embedded clinical tissue blocks and tissue microarrays.
  Thomas W. Powers, Benjamin A. Neely, Yuan Shao, Huiyuan Tang, Dean A. Troyer
  Plos One. 2014-09-03

Journal Articles

• A Five‐CpG DNA Methylation Score to Predict Metastatic‐Lethal Outcomes in Men Treated with Radical Prostatectomy for Localized Prostate Cancer  
  Scott A Tomlins, Raymond Lance, Dean Troyer, Colin C Pritchard, The Prostate
• Clinical validation of an epigenetic assay to predict negative histopathological results in repeat prostate biopsies  
  Partin AW, Van Neste L, Klein EA, Marks LS, Gee JR, Troyer DA, Rieger-Christ K, Jones JS, Magi-Galluzzi C, Mangold LA, Trock BJ, Lance RS, Bigley JW, Van Criekinge W, ..., J Urol, 1/1/2014
• In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine  
  Principe S, Jones EE, Kim Y, Sinha A, Nyalwidhe JO, Brooks J, Semmes OJ, Troyer DA, Lance RS, Kislinger T, Drake RR, Proteomics, 5/1/2013
• Optimization of initial prostate biopsy in clinical practice: sampling, labeling and specimen processing  
  Bjurlin MA, Carter HB, Schellhammer P, Cookson MS, Gomella LG, Troyer D, Wheeler TM, Schlossberg S, Penson DF, Taneja SS, J Urol, 1/1/2013
• Identification of differentially expressed proteins in direct expressed prostatic secretions of men with organ-confined versus extracapsular prostate cancer  
  Kim Y, Ignatchenko V, Yao CQ, Kalatskaya I, Nyalwidhe JO, Lance RS, Gramolini AO, Troyer DA, Stein LD, Boutros PC, Medin JA, Semmes OJ, Drake RR, Kislinger, Mol Cell Proteomics, 1/1/2012
• Cancer detection and biopsy classification using concurrent histopathological and metabolomics analysis of core biopsies  
  Brown MV, McDunn JE, Gunst PR, Smith EM, Milburn MV, Troyer DA, Lawton KA, Genome Medicine, 1/1/2012
• Identification of prostate-enriched proteins by in-depth proteomic analyses of expressed prostatic secretions in urine  
  Principe S, Kim Y, Fontana S, Ignatchenko V, Nyalwidhe JO, Lance RS, Troyer DA, Alessandro R, Semmes OJ, Kislinger T, Drake RR, Medin JA, J Proteome Res, 1/1/2012
• Molecular preservation by extraction and fixation, mPREF: a method for small molecule biomarker analysis and histology on exactly the same tissue  
  Shuster JR, Lance RS, Troyer DA, BMC Clinical Pathology, 1/1/2011
• Blockade of transforming growth factor-beta (TGFBeta) signaling inhibits osteoblastic tumorigenesis by a novel human prostate cancer cell line  
  Mishra S, Tang Y, Wang L, Degraffenried L, Yeh IT, Werner S, Troyer D, Copland JA, Sun LZ, Prostate, 1/1/2011
• Prostate cancer detected by methylated gene markers in histopathologically cancer-negative tissues from men with subsequent positive biopsies  
  Troyer, DA, Lucia, MS, de Bruine, AP, Mendez-Meza, R, Baldewijns, MM, Dusnscomb, N, Van Engeland, M, McAskill, T, Biuerau, K, Louwagie, J, Bigley, JW, Cancer Epidemiology Biomarkers Prev, 10/1/2009
• Involvement of FLIP in 2-methoxyestradiol induced tumor regression in transgenic adenocarcinoma of mouse prostate (TRAMP) model  
  Ganapathy M, Ghosh R, Jianping X, Zhang X, Bedolla R, Schoolfield J, Yeh IT, Troyer DA, Olumi AF, Kumar AP, Clin Cancer Res, 1/1/2009
• Imaging Mass Spectrometry of a Specific Fragment of MEKK2 Discriminates Cancer from Uninvolved Prostate Tissue  
  Cazares, L.H., Troyer, D. Mendrinos, S., Lance, R.S., Clements, M.A., Drake, R.R. and Semmes, O.J., Clin. Cancer Res, 1/1/2009
• Nonhuman primates as models for studies of prostate specific antigen and prostatic diseases  
  Mubiru, JN, Hubbard, GB, Dick, EJ, Furman, J, Troyer, DA, Rogers, J, The Prostate, 1/1/2008
• Characterization of PacMetUT1, a recently isolated human prostate cancer cell line  
  Troyer, DA, Tang, Y, Bedolla, R. Adhvaryu, SG, Thompson, IM, Abboud-Werner, S., Sun, L.-Z. Friedrichs, WE, deGraffenried, LA, The Prostate, 1/1/2008
• Akt/cAMP-responsive element binding protein/cyclin D1 network: a novel target for prostate cancer inhibition in transgenic adenocarcinoma of mouse prostate model media...  
  Kumar AP, Bhaskaran S, Ganapathy M. Crosby K, Davis MD, Kochunov P, Schoolfield J, Yeh IT, Troyer DA, Ghosh R, Clinical Cancer Res, 1/1/2007
• Determining risk of biochemical recurrence in prostate cancer by immunohistochemical detection of PTEN expression and Akt activation  
  Bedolla R. Prihoda TJ. Kreisberg JI. Malik SN. Krishnegowda NK. Troyer DA. Ghosh PM, Clinical Cancer Research, 1/1/2007
• Obesity, adipokines, and prostate cancer in a prospective population-based study  
  Baillargeon J. Platz EA. Rose DP. Pollock BH. Ankerst DP. Haffner S. Higgins B. Lokshin A. Troyer D. Hernandez J. Lynch S. Leach RJ. Thompson IM, Cancer Epidemiology, Biomarkers and Prevention, 1/1/2006
• Detection of recurrent copy number loss at Yp112 involving TSPY gene cluster in prostate cancer using array-based comparative genomic hybridization  
  Vijayakumar S, Hall DC, Reveles XT, Troyer DA, Thompson IM, Garcia D, Xiang R, Leach RJ, Johnson-Pais TL, Naylor SL, Cancer Research, 1/1/2006
• The association of body mass index and prostate specific antigen in a population-based study  
  Baillargeon J, Pollock BH, Kristal A, Bradshaw P, Hernandez J, Basler J, Higgins B, Lynch S, Rozanski T, Troyer D, Thompson I, Cancer, 1/1/2005
• Signal Transduction Pathways in Androgen-Dependent and -Independent Prostate Cancer Cell Proliferation  
  Ghosh, P.M., Malik, S.N., Bedolla, R.G., Wang, Y., Mikhailova, M., Prihoda, T.J., Troyer, D.A., Kreisberg, J.I., Endocrine Related Cancers, 1/1/2005
• Promise and Challenge: Markers of Prostate Cancer Detection, Diagnosis and Prognosis  
  Troyer DA. Mubiru J., Leach, R., Naylor, S, Disease Markers, 1/1/2004
• Relationship of body mass index and prostate specific antigen in a population-based study  
  Thompson IM, Leach R, Troyer D, Pollock B, Naylor S, Higgins B, Urologic Oncology, 1/1/2004
• The Early Detection Research Network Surface-Enhanced Laser Desorption and Ionization Prostate Cancer Detection Study: A Study in Biomarker Validation in Genitourinary...  
  Grizzle WE, Semmes OJ, Basler J, Izbicka E, Feng Z, Kagan J, Adam BL, Troyer D, Srivastava S, Thornquist M, Zhang Z, Thompson IM, Urologic Oncology, 1/1/2004
• Alternative Spliced Variants of the Alpha-methyl-acyl-CoA Racemase Gene and their Expression in Prostate Cancer  
  Mubiru, J. N., Shen-Ong, G.L., Valente, A.J., and Troyer, D.A., Gene, 1/1/2004
• Prostate Cancer Prevention: What do we know now and when will we know more?  
  Thompson, I.M., Basler, J., Hensley, D., Merveldt, D., Jenkins, C.A., Higgins, B., Leach, R., Troyer, D., Pollock, B., Clinical Prostate Cancer, 1/1/2003
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Books/Book Chapters

• Translational Pathology of Early Cancer 
  Page 441 - 459Cazares LH, Drake RR, Esquela-Kirscher A, Lance RS, Semmes OJ, Troyer DAEditors: Sudhir Srivastava, William E. Grizzle.IOS Press2012
• Tissue Proteomics: Approaches for Pathways, Biomarkers, and Drug Discovery 
  Chapter: Biorepository Standards and Protocols for Collecting, Processing, and Storing Human Tissues. 
  Page 193 - 220Troyer, DAEditors: Brian Liu.Humana Press, Totowa, NJ2008
• Nutrition and Immunology: Principles and Practice 
  Chapter: Caloric Intake: Sources, Deficiencies and Excess-An Overview 
  Page 35 - 47Troyer DA, Fernandes, GEditors: M. Eric Gershwin; J.Bruce German; Carl Keen.Humana Press2000
• Methods in Enzymology 
  Chapter: Isolation and study of glomerular cells. 
  Page 141 - 152Troyer DA and Kreisberg JIEditors: Sidney Fleischer & Becca Fleischer.Academic Press1990
• Cyclosporine: Diagnosis and Management of Associated Renal Injury 
  Chapter: Pathology and pathogenesis of nephrotoxic membrane damage. 
  Page 63 - 71Schwertz DW, Troyer DA, Kreisberg JI and Venkatachalam MAEditors: Barry D. Kahan.Grune & Stratton, Inc.1986
• Drugs and Kidney 
  Chapter: Pathogenesis of membrane damage in aminoglycoside and mercuric chloride toxicity. Insight from in vitro models. 
  Page 107 - 122Schwertz DW, Troyer DA, Kreisberg JI and Venkatachalam MAEditors: T Bertani, G Remuzzi and S Garattini.Raven Press, New York1986
• Twenty Common Genitourinary Problems 
  Chapter: Prostate Cancer: Prostate Specific Antigen, Screening, Clinical Management, and Prevention. 
  Joel Teichman, Thompson IM, Troyer DMcGraw-Hill, New York, NY
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Abstracts/Posters

• Metabolite Assay and Histology on Exactly the Same Tissue.
  Dean Troyer, Shahab Shamsi, GTC Conference, Boston, MA, 1/1/2014
• FISH Analysis of 637 Prostate Cancers: Association of PTEN genomic deletion with earlier onset of disease progression and worse prognosis.
  Dean Troyer, Tamara Jamaspishvili, Jennifer Good, Jeremy A. Squire, Ribeirao Preto, Wei Wei, Ziding Feng, CAPIT Canary Pathology Team Investigating Tissue Biomarkers, AUA, Orlando, FL, 1/1/2014
• FISH analysis of 637 prostate cancers: associations of PTEN genomic deletion with higher Gleason score and biochemical recurrence.
  Dean Troyer, Tamara Jamaspishvili, Jennifer Good, Jeremy Squire and-CAnary PathologyTeam Investigating Tissue biomarkers (CAPIT), USCAP, San Diego, CA, 1/1/2014
• Multicenter Validation Study of a Tissue Methylation Assay to Predict Histopathologically Cancer-Negative Repeat Prostate Biopsies.
  Dean Alan Troyer, MD, AUA, 1/1/2014
• Metabolites and histology on exactly the same biopsy tissue.
  Dean A Troyer, Jeffrey R Shuster, Raymond Lance, USCAP, Baltimore, MD, 3/2/2013
• Defining the molecular tumor margin regions of clear cell renal carcinoma tissues by MALDI-MS imaging of lipid and glycan species.
  Richard Drake, Thomas Powers, Ellen Jones, Anand Mehta, Raymond S. Lance, Dean A. Troyer, ASCO Genitoruinary Cancers Symposium, San Francisco, CA, 1/24/2013
• Metabolite assay and histology on exactly the same tissue.
  Dean A. Troyer, Jeffrey R. Shuster, Sarah Baxter, Mingming Su, Ray Lance, David H Murdock, ASCO Genitourinary Cancers Symposium, San Francisco, CA, 1/24/2013
• Metabolomics and histology on exactly the same ex vivo prostate biopsy.
  Shuster JR, Lance R, Troyer D, ASCO GU Symposium, San Francisco, CA, 1/1/2012
• Metabolomics and Histology on the Same Tissue Biopsy.
  Shuster JR, Lance R, Adam K-P, Alexander D, Troyer D, ASCO GU Symposium, Orlando, FL, 1/1/2011
• Combining Prostate Cancer Region Predictions from MALDI Spectra Processing and Texture Analysis.
  Jiang Li, Ayyappa Vadlamudi, Shao-Hui Chuang, Xiaoyan Sun, Bo Sun, Frederic McKenzie, Lisa Cazares, Julius Nyalwidhe, Dean Troyer and John Semmes, Proceedings10th IEEE Conference on Bioinformatics & Bioengineering, 1/1/2010
• Adjacent Slice Prostate Cancer Prediction to Inform MALDI Imaging Biomarker Analyses.
  Shao-Hui Chuang, Xiaoyan Sun, Lisa Cazares, Julius Nyalwidhe, Dean Troyer, O. John Semmes, Jiang Li, Frederic D. McKenzie, Proceedings of SPIE, Medical Imaging, 1/1/2010
• The VEGF +405 Polymorphism is Associated with Prostate Cancers of Poor Prognosis.
  Canby-Hagino, E., Garcia, D., Thompson, I.M., Troyer, D., Baillargeon, J., Brand, T., Leach, R., Naylor, S., Society of Urology Oncology, 1/1/2005
• Differential expression and quantitation of 5-alpha reductase (5alphaR) human prostate.
  S Chikkamuniyappa, R McMasters, P Ghosh, I Thompson, R Leach, D Troyer, United States and Canadian Academy of Academic Pathologists, San Antonio, TX, 1/1/2005
• Variations in the Activity of the type 1 5alpha-Reductase Isoenzyme in Prostate Cancer.
  Richard W Norman, Catherine B Lazier, Robert C Douglas, Lynn N Thomas, R Gupta, Dan Fontaine, Dean A Troyer, Ian M Thompson, Roger S. Rittmaster, Am Urological Association Meeting, 1/1/2003
• Diagnostic Prostate Biopsies: Use of Frozen Section for Preservation of RNA and Proteins for Biomarker Studies.
  Jaime Furman, Gretchen Schantz, Hee Tae Kim, Ian Thompson, Powel Brown and Dean Troyer, AACR Cancer Prevention Meeting, Boston, MA, 10/1/2002
• A Prostate Cancer-specific Gene Set based on Whole Genome Oligonucleotide Expression Profiling.
  Shen, G. L., Higgs, B., Leach, R., Thompson, I.M., Troyer, D.A., 93rd Annual Meeting, Am. Assoc. Cancer Res., San Francisco, CA, 4/6/2002
• Analysis of Gene Expression in Prostate Cancer.
  Troyer, D.A., Leach R., Thompson, I.M., Shen, G.L., Second Annual Early Detection Research Network (EDRN) Scientific Workshop, Seattle, WA, 10/14/2001
• Descrptive and Comparative Microanatomy in Zebrafish: A Basis for Pathologic Correlations.
  Troyer, d.A., Benglis, D., Green, R., Jagadeeswaran, P., Texas Zebrafish Development and Genetics Meeting, San Antonio, TX, 7/26/2001
• The Expression of Multiple Calreticulin Genes in the Zebrafish.
  Valente, A.J., Abramova, M.E., Gamez, M.D., Pearson, D.W., Gregory, M., Troyer, D., Jagadeeswaran, P., and Clark, R.A., Texas Zebrafish Development and Genetics Meeting, San Antonio, TX, 7/26/2001
• Renal vasculopathy associated with sirolimus-cyclosporine A combination in recipients of cadaveric renal transplants.
  Daniel J. Riley, Charles R. Nolan III, Wajeh Qunibi and Dean A. Troyer, World Congress of Nephrology, University of Texas HSC, San Antonio, TX, 1/1/2001
• Suppression of Prostate Cancer Tumorigenicity by Chromosome 18.
  Padalecki, S.S., Troyer, D.A., Johnson-Pais, T.L., Weldon, K., Killary, A.M., and Leach, R.J., Early Detection Research Network (EDRN) Scientific Workshop, Chicago, IL, 9/25/2000
• MMP-8 Expression in Development and Human Melanoma.
  Giambernardi, T.A., Sakaguchi, A.Y., Rodeck, U., Steffensen, B., Pavlin, D., Gluhak, J., Troyer, D., and Klebe, R.J., San Antonio Cancer Institute 10th Annual Symposium, 7/1/2000
• Increased expression of active (membrane-bound) RhoA small GTPase in preneoplastic and early neoplastic but not high grade prostate cancer.
  Malik, S.N., Prihoda, T., Troyer, D., Ghosh, P., Brattain, M., Kreisberg, J., Proc. Am. Assoc. Ca. Res., 1/1/2000
• Beliefs and attitudes towards hereditary prostate cancer.
  Arar, N.H., Sarosdy, M., Thompson, I., Harris, M., Troyer, D., Hernandez, L., Garcia, J., Hunt, L., and Plaetke, R., American Journal of Human Genetics, Denver Meeting, 10/1/1998
• Effects of insulin on diacylglycerol metabolism in cultured glomerular mesangial cells.
  Troyer DA, Federation of American Societies for Experimental Biology, Las Vegas, NV, 5/1/1998
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Lectures

• "Metabolite assay and histology on exactly the same tissue." Invited Lecture 
  Niskayuna, NY - 10/2/2013
• "Pathology is phenotyping. What do pathologists do? How do they do it?" 
  San Diego, CA - 9/12/2013
• Invited Speaker: "Metabolomics and Histology on Exactly the Same Tissue" 
  Sentry Centers Midtown East, New York City, NY - 11/16/2011
• "Metabolomics and Histology on the Exact Same Tissue Sample: Preservation by Extraction and Fixation." 
  Washington, DC - 5/1/2011
• "A New Paradigm for Translational Research" 
  Discovery Park/Bindley Bioscience Research Park, Purdue University, Lafayette, IN - 12/21/2005
• "Biorepositories" 
  Monterrey, Mexico - 10/27/2005
• Transplant Surgery Grand Rounds: "Morphological Aspects of Renal Transplant Rejection." 
  UTHSCSA - 10/26/2001
• "Prostate Pathology: Current Status." 
  San Antonio, TX - 10/20/2001
• "Descriptive and comparative microanatomy in zebrafish: A basis for pathologic correlations." 
  San Antonio, TX - 7/26/2001
• "Molecular Genetics of Prostate Cance" 
  3/29/1999
• "Histotechniques and Histopathology of Renal Disease" 
  3/19/1999
• "Prostate Cancer-What does the DNA say?" 
  12/1/1998
• Teleconference: "Renal Biopsy Techniques" 
  9/1/1998
• "Renal Biopsy Interpretation." 
  San Antonio, TX - 1/1/1998
• "Prostate Cancer Research in San Antonio" 
  San Antonio, TX - 10/3/1995
• "Clinico-Pathological Correlations in Diabetes Mellitus" 
  San Antonio, TX - 5/1/1991
• "Renal Pathology in Diabetes Mellitus" 
  Monterrey, Nueva Leon, Mexico - 5/1/1991
• "Phospholipid Metabolism in Mesangial Cells" 
  Department of Pathology, Tulane University School of Medicine, New Orleans, LA - 4/1/1991
• "Renal Biopsy Interpretation" 
  Nephrology Division, Brooke Army Medical Center, San Antonio, TX - 1/1/1991
• "Phospholipid Metabolism in Mesangial Cells." 
  Department of Pathology, Medical College of Wisconsin, Milwaukee, WI - 6/1/1990
• "The Biology of Mesangial Cell Phosphoinositides-Possible Relevance to Insulin and Insulin Like Growth Factor Action." 
  The University of Texas Health Science Center at San Antonio, Department of Pathology, San Antonio, - 9/1/1988
• "A Role for an Inositolglycan-phospholipid in Hormone Induced Contraction of Mesangial Cells." 
  University of New Mexico, School of Medicine, Albuquerque, NM - 5/1/1988
• "A Glycan Phospholipid-A Role for Contraction of Cultured Mesangial Cells." 
  University of Maryland Medical School, Department of Pathology, Baltimore, MD - 7/1/1987
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Other

• "AUA Prostate Biopsy White Paper" 
  Dr. Samir Taneja, and AUA Workgroup
  1/1/2013
• Emerging Biomarkers in Prostate Cancer. 
  Troyer, D, Aging Health Future Medicine, 2:579-588
  1/1/2006
• "New Approaches to Prostate Cancer: Markers of Early Diagnosis, Prognosis, and Risk" (Lay Summary distributed to members of Congress and staff) 
  Dean Alan Troyer, MD, The Men's Health Network Brochure "MEN'S HEALTH WEEK-Awareness.Prevention.Education.Family."
  6/4/2003
• Effects of Calorie Restriction and w-3 Dietary Supplementation on Aging in Short- and long-Lived Rodents. 
  Troyer, D., Venkatraman, J., Fernandes, G., AGE, 21, 175-182
  1/1/1998
• Interaction of Vitamin E with n-6 and n-3 Polyunsaturated Fatty Acids. (Invited Commentary) 
  Fernandes, G., Venkatraman, J., Troyer, D., International Society for the Study of Fatty Acids and Lipids (ISSFAL) Newsletter 3:10-13
  1/1/1996
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