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Office
1515 Holcombe Blvd
Houston, TX 77030Phone+1 713-792-6161
Education & Training
- Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Internal Medicine, 1978 - 1983
- Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Infectious Disease, 1980 - 1982
- Harvard Medical SchoolClass of 1978
- Princeton UniversityA.B., Chemistry, Cum Laude, 1970 - 1974
Certifications & Licensure
- FL State Medical License 2021 - Present
- TX State Medical License 2000 - 2026
- PA State Medical License 1984 - 2000
- OH State Medical License 1982 - 1986
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Infectious Disease
Awards, Honors, & Recognition
- Who’s Who in America Marquis, 2007
- Who's Who in Medicine and Healthcare Marquis, 2006
- Who's Who in Science and Engineering Marquis, 2006
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Publications & Presentations
PubMed
- 72 citationsModulation of STAT3 folding and function by TRiC/CCT chaperonin.Moses M. Kasembeli, Wilson Chun Yu Lau, Soung Hun Roh, T. Kris Eckols, Judith Frydman
Plos Biology. 2014-04-22 - 13 citationsChaperonin-containing TCP-1 complex directly binds to the cytoplasmic domain of the LOX-1 receptor.Deenadayalan Bakthavatsalam, Roh Hun Soung, David J. Tweardy, Wah Chiu, Richard A. F. Dixon
FEBS Letters. 2014-06-13 - 58 citationsContribution of the Type II Chaperonin, TRiC/CCT, to OncogenesisSoung Hun Roh, Moses M. Kasembeli, Deenadayalan Bakthavatsalam, Wah Chiu, David J. Tweardy
International Journal of Molecular Sciences. 2015-11-06
Journal Articles
- Adult Intracranial Tuberculoma Case Series from Houston, Texas: a report of 13 consecutive patientsKelly JD, Teeter LD, Graviss EA and Tweardy DJ, Scand J Infect Dis, 10/1/2011
- IL-6-Mediated Activation of Stat3 alpha Prevents Trauma/Hemorrhagic Shock-Induced Liver InflammationMoran A, Thacker SA, Arikan AA, Mastrangelo MA, Wu Y, Yu B and Tweardy DJ, PLoS ONE, 6/29/2011
- Stat5: From Breast Development to Cancer Prognosis, Prediction, and ProgressionTweardy DJ and Chang JC, J Clin Oncol, 6/1/2011
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Books/Book Chapters
Lectures
- Drugging STAT proteins to treat inflammation and cancerInternal Medicine and Cancer Survivorship Grand Rounds, UT M.D. Anderson Cancer Center, Houston, TX - 11/16/2012
- Drugging STAT proteins to treat cancer and inflammatory disordersVerna and Marrs McLean Department of Biochemistry and Molecular Biology Research Seminar, Baylor Col - 4/26/2012
- Contributions of Abnormal Proteostasis to Cellular DysfunctionPlenary Symposium Presentation, 34th Annual Conference on Shock, Norfolk, VA - 6/12/2011
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Press Mentions
- Biopharmaceutical Co. Tvardi Therapeutics Raises $74M to Advance Clinical Pipeline, Grow TeamJune 23rd, 2021
- Tvardi Snags $74M to Weed the Tumor Garden with STAT3 InhibitorJune 23rd, 2021
- 12 COVID-19 Vaccine Questions, AnsweredAugust 11th, 2020
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Grant Support
- STAT3 Probes That Target Breast Cancer Stem CellsNational Cancer Institute2010–2011
- Research Training In Infections And ImmunityNational Institute Of Allergy And Infectious Diseases2003–2011
- Reversal Of Hypovolemic Circulatory Collapse By IL-6National Heart, Lung, And Blood Institute2004–2007
- Mechanisms Of G-CSF Receptor Mediated DifferentiationNational Cancer Institute1999–2006
- STAT3 Interactions In Cell Growth And DifferentiationNational Cancer Institute1999–2003
- Neutrophils And G-CSF In Hemorrhagic ShockNational Institute Of General Medical Sciences1997–1999
- Mechanisms Of G-CSF Receptor Mediated DifferentiationNational Cancer Institute1996–1999
- Research Training In AIDS, STDS &Intracellular PATHNational Institute Of Allergy And Infectious Diseases1998
- Suppression Of Hemopoiesis By A Novel LymphokineNational Heart, Lung, And Blood Institute1986–1990
- Suppression Of Hemopoiesis By A Novel LymphokineNational Heart, Lung, And Blood Institute1986
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