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Office
1515 Holcombe Blvd
Houston, TX 77030Phone+1 713-792-6161
Education & Training
- Case Western Reserve University/University Hospitals Cleveland Medical CenterResidency, Internal Medicine, 1978 - 1983
- Case Western Reserve University/University Hospitals Cleveland Medical CenterFellowship, Infectious Disease, 1980 - 1982
- Harvard Medical SchoolClass of 1978
- Princeton UniversityA.B., Chemistry, Cum Laude, 1970 - 1974
Certifications & Licensure
- FL State Medical License 2021 - Present
- TX State Medical License 2000 - 2026
- PA State Medical License 1984 - 2000
- OH State Medical License 1982 - 1986
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Infectious Disease
Awards, Honors, & Recognition
- Who’s Who in America Marquis, 2007
- Who's Who in Medicine and Healthcare Marquis, 2006
- Who's Who in Science and Engineering Marquis, 2006
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Publications & Presentations
PubMed
- 113 citationsIdentification and Characterization of Signal Transducer and Activator of Transcription 3 Recruitment Sites within the Epidermal Growth Factor ReceptorHuang Shao, Haiyun Y. Cheng, Richard G. Cook, David J. Tweardy
Cancer Research. 2003-07-15 - 113 citationsContribution of STAT3 to Inflammatory and Fibrotic Diseases and Prospects for its Targeting for Treatment.Moses M. Kasembeli, Uddalak Bharadwaj, Prema Robinson, David J. Tweardy
International Journal of Molecular Sciences. 2018-08-05 - 170 citationsTargeting Janus Kinases and Signal Transducer and Activator of Transcription 3 To Treat Inflammation, Fibrosis, and Cancer: Rationale, Progress, and CautionUddalak Bharadwaj, Moses M. Kasembeli, Prema Robinson, David J. Tweardy
Pharmacological Reviews. 2020-04-01
Journal Articles
- Adult Intracranial Tuberculoma Case Series from Houston, Texas: a report of 13 consecutive patientsKelly JD, Teeter LD, Graviss EA and Tweardy DJ, Scand J Infect Dis, 10/1/2011
- IL-6-Mediated Activation of Stat3 alpha Prevents Trauma/Hemorrhagic Shock-Induced Liver InflammationMoran A, Thacker SA, Arikan AA, Mastrangelo MA, Wu Y, Yu B and Tweardy DJ, PLoS ONE, 6/29/2011
- Stat5: From Breast Development to Cancer Prognosis, Prediction, and ProgressionTweardy DJ and Chang JC, J Clin Oncol, 6/1/2011
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Books/Book Chapters
Lectures
- Drugging STAT proteins to treat inflammation and cancerInternal Medicine and Cancer Survivorship Grand Rounds, UT M.D. Anderson Cancer Center, Houston, TX - 11/16/2012
- Drugging STAT proteins to treat cancer and inflammatory disordersVerna and Marrs McLean Department of Biochemistry and Molecular Biology Research Seminar, Baylor Col - 4/26/2012
- Contributions of Abnormal Proteostasis to Cellular DysfunctionPlenary Symposium Presentation, 34th Annual Conference on Shock, Norfolk, VA - 6/12/2011
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Press Mentions
- Biopharmaceutical Co. Tvardi Therapeutics Raises $74M to Advance Clinical Pipeline, Grow TeamJune 23rd, 2021
- Tvardi Snags $74M to Weed the Tumor Garden with STAT3 InhibitorJune 23rd, 2021
- 12 COVID-19 Vaccine Questions, AnsweredAugust 11th, 2020
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Grant Support
- STAT3 Probes That Target Breast Cancer Stem CellsNational Cancer Institute2010–2011
- Research Training In Infections And ImmunityNational Institute Of Allergy And Infectious Diseases2003–2011
- Reversal Of Hypovolemic Circulatory Collapse By IL-6National Heart, Lung, And Blood Institute2004–2007
- Mechanisms Of G-CSF Receptor Mediated DifferentiationNational Cancer Institute1999–2006
- STAT3 Interactions In Cell Growth And DifferentiationNational Cancer Institute1999–2003
- Neutrophils And G-CSF In Hemorrhagic ShockNational Institute Of General Medical Sciences1997–1999
- Mechanisms Of G-CSF Receptor Mediated DifferentiationNational Cancer Institute1996–1999
- Research Training In AIDS, STDS &Intracellular PATHNational Institute Of Allergy And Infectious Diseases1998
- Suppression Of Hemopoiesis By A Novel LymphokineNational Heart, Lung, And Blood Institute1986–1990
- Suppression Of Hemopoiesis By A Novel LymphokineNational Heart, Lung, And Blood Institute1986
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