David B Sykes MD PhD
Clotting Disorder, Myeloproliferative Disorder Hematology-Oncology
Mass General Hospital Division of Hematology
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55 Fruit StBoston, MA 02114
Phone+1 617-724-4000
Fax+1 617-724-6801
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Education & Training
Mass General Brigham/Brigham and Women's Hospital/Massachusetts General Hospital/Dana-Farber Cancer InstituteFellowship, Hematology and Medical Oncology, 2007 - 2011
Mass General Brigham/Massachusetts General HospitalResidency, Internal Medicine, 2004 - 2007
University of California San Diego School of MedicineClass of 2004
Certifications & Licensure
MA State Medical License 2006 - 2025
American Board of Internal Medicine Internal Medicine- American Board of Internal Medicine Hematology
- American Board of Internal Medicine Medical Oncology
Publications & Presentations
PubMed
- Single-cell and spatial transcriptomics reveal a tumor-associated macrophage subpopulation that mediates prostate cancer progression and metastasis.Shenglin Mei, Hanyu Zhang, Taghreed Hirz, Nathan Elias Jeffries, Yanxin Xu
Molecular Cancer Research. 2025-03-19 - PSTK inhibition activates cGAS-STING, precipitating ferroptotic cell death in leukemic stem cells.Lingli He, Ting Zhao, Wei Zhong Leong, Azeem Sharda, Christina Mayerhofer
Blood. 2025-02-05 - DHODH Inhibition Suppressesand Inhibits the Growth of Medulloblastoma in a Novel In Vivo Zebrafish Model.Ioanna Tsea, Thale Kristin Olsen, Panagiotis Alkinoos Polychronopoulos, Conny Tümmler, David B Sykes
Cancers. 2024-12-13
Abstracts/Posters
- Functionally Distinct Subsets of Monocytes in Mouse and Human BloodDavid B Sykes, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/8/2019
- What Links Neutropenia to Immature Cardiolipin in Patients with Barth Syndrome (tafazzin-deficiency)?David B Sykes, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
- Niche Transfer of Small Non-Coding RNAs Regulates Hematopoietic Response to StressDavid B Sykes, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Press Mentions
Telangiectasias: When Is It TEMPI Time?October 19th, 2022- Case Records of the Massachusetts General HospitalMarch 29th, 2022
- Case Records for the MGHMarch 28th, 2022
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Professional Memberships
- Member
Other Languages
- French
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