DavidH.SachsMD

Allergy & Immunology • Boston, MA

Clinical & Laboratory Immunology

Professor, Surgery, Massachusetts General Hospital, Harvard Medical School

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Office
Bldg. 149-9019, 13th Street
Boston, MA 02129
Phone+1 617-726-4065

Fax+1 617-726-4067

Education & Training

Massachusetts General HospitalInternship, Transitional Year, 1968 - 1969
Harvard Medical SchoolClass of 1968

Certifications & Licensure

MA State Medical License 1987 - 2026

Awards, Honors, & Recognition

Elected Member Institute of Medicine, 1996

Clinical Trials

Reducing the Risk of Transplant Rejection: Simultaneous Kidney and Bone Marrow Transplant Start of enrollment: 2003 Jun 01
Completed
Phase 1
Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection Start of enrollment: 2008 Dec 01
Completed
Phase 2
Renal Allograft Tolerance Through Mixed Chimerism Start of enrollment: 2013 Mar 01
Completed
Phase 1, Phase 2

Publications & Presentations

PubMed

Durable mixed chimerism may permit subsequent immunosuppression-free intestinal transplantation-A proof-of-principle study.
Satyajit Patwardhan, Muhammed E Gunes, Elin Manell, Julie Hong, Philip Jordache
American Journal of Transplantation. 2024-10-22
Detailed surgical description of porcine vascularized thymus lobe transplantation.
M Esad Gunes, Sho Fujiwara, Daniel H Wolbrom, Alexander Cadelina, Susan Qudus
Frontiers in Transplantation. 2024-01-01
2 citations
Xenotransplantation and exotransplantation: Strategies to expand the number of donor organs.
Daniel J Garry, Joshua I Weiner, Sarah M Greising, David H Sachs, Mary G Garry
Xenotransplantation. 2023-01-01

Journal Articles

Ontak-like Human IL-2 Fusion Toxin
David H. Sachs, Joren C. Madsen, Joren C Madsen, David H Sachs, ScienceDirect

Press Mentions

Healthy ConversationsMarch 23rd, 2022
UCLA Health Advances Pioneering Protocol to Enable Transplant Recipients to Thrive Without Antirejection DrugsFebruary 1st, 2022
Four Breakthroughs That Led to the Pig Heart TransplantJanuary 18th, 2022
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Grant Support

Thymic Rejuvenation For The Induction Of Transplantation ToleranceNational Institute Of Allergy And Infectious Diseases2010–2012
Tolerance Induction In A Galt-Ko Pig-To-Baboon Model Through Mixed ChimerismNational Institute Of Allergy And Infectious Diseases2011
Galt-Ko Pigs Expressing Primate CD47 To Facilitate Organ XenograftsNational Institute Of Allergy And Infectious Diseases2010–2011
Administrative CoreNational Institute Of Allergy And Infectious Diseases2008–2011
Tolerance To Composite Islet-Kidney Transplants In BaboonsNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2011
Tolerance To Vascularized Allografts In MiniswineNational Institute Of Allergy And Infectious Diseases2006–2011
A Tolerance Approach To XenotransplantationNational Institute Of Allergy And Infectious Diseases2001–2011
Training In Transplantation BiologyNational Institute Of Allergy And Infectious Diseases1998–2011
Genetics And Mechanisms Of DLI Effects Following Non-Myeloblative HCTNational Cancer Institute2010
Genetics And Mechanisms Of DLI Effects Following Non-Myeloblative HCTNational Cancer Institute2006–2009
Tolerance Induction In A Gait-Ko Pig-To-Baboon Model Through Establishment ......National Institute Of Allergy And Infectious Diseases2005–2009
Tolerance Induction In A Galt-Ko Pig-To-Baboon Model Through Establishment Of MIXNational Institute Of Allergy And Infectious Diseases2007
Islet-Kidney Transplants For Treatment Of Diabetic ESRDNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2006
Tolerance To Vascularized Allografts In MiniswineNational Institute Of Allergy And Infectious Diseases1996–2005
Islet-Kidney Transplants For Treatment Of Diabetic ESRDNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2003
Xenograft Tolerance Through Mixed ChimerismNational Institute Of Allergy And Infectious Diseases2000–2002
Mixed Chimerism In Miniature SwineNational Cancer Institute2000–2002
Mixed Hematopoietic Cell Chimerism In A ModelNational Heart, Lung, And Blood Institute1999–2002
Tolerance To Heart Transplants In Miniature SwineNational Heart, Lung, And Blood Institute1998–2002
Thymus TransplantationNational Institute Of Allergy And Infectious Diseases1996–2002
Bone Marrow Culture And Engraftment In A Swine ModelNational Heart, Lung, And Blood Institute1995–1999
Transplantation Of T Cell-Depleted Marrow In MiniswineNational Cancer Institute1994–1997
Retroviral Transduction Of Class I MHC GeneNational Heart, Lung, And Blood Institute1993–1997
Tolerance To Vascular AllograftsNational Institute Of Allergy And Infectious Diseases1994–1995
Bone Marrow Transplantation Across MHC BarriersNational Cancer Institute1992–1994
Bone Marrow Culture And Engraftment In A ModelNational Heart, Lung, And Blood Institute1991–1994
Tolerance To Vascular Allografts In Miniature SwineNational Institute Of Allergy And Infectious Diseases1991–1993
A Flexible Scheduling Program For Longitudinal StudiesNational Institute On Drug Abuse1991
Optimum Dose And Schedule For Nicotine Gum TreatmentNational Institute On Drug Abuse1988–1991
A Flexible Scheduling Program For Longitudinal StudiesNational Institute On Drug Abuse1990