David R Rubinow MD
Professor and Chair of Psychiatry; Professor of Medicine; Director, UNC Innovation and Health Care System Transformation; and Director, UNC Center for Women’s Mood Disorders
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101 Manning DrChapel Hill, NC 27514
Phone+1 919-966-8596
Fax+1 919-843-5515
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Education & Training
National Institutes of Health Clinical CenterResidency, Psychiatry, 1979 - 1981
Yale-New Haven Medical CenterResidency, Psychiatry, 1976 - 1979
Uconn School Of MedicineClass of 1975
Certifications & Licensure
NC State Medical License 2006 - 2025
MD State Medical License 1980 - 2007
DC State Medical License 1982 - 2006
American Board of Psychiatry and Neurology Psychiatry
Awards, Honors, & Recognition
- Elected Member Institute of Medicine, 2011
Clinical Trials
- Neurophysiology of Postpartum Depression in an Experimental Model of Pregnancy and Parturition Start of enrollment: 2013 Aug 01
Publications & Presentations
PubMed
- Esr1-Dependent Signaling and Transcriptional Maturation in the Medial Preoptic Area of the Hypothalamus Shapes the Development of Mating Behavior during Adolescence.Koichi Hashikawa, Yoshiko Hashikawa, Brandy Briones, Kentaro Ishii, Yuejia Liu
Biorxiv. 2025-02-26 - Cortisol and ACTH response to Dex/CRH testing and 24-hour urine free cortisol levels in women with and without premenstrual dysphoric disorder.Constance X Zou, Gioia M Guerrieri, Pedro E Martinez, Xiaobai Li, Rivka Ben Dor
Psychoneuroendocrinology. 2025-02-01 - 4 citationsClosed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive Disorder: An Open-Label Pilot Study.Tobias Schwippel, Francesca Pupillo, Zachary Feldman, Christopher Walker, Leah Townsend
The American Journal of Psychiatry. 2024-09-01
Journal Articles
- Safety of Estradiol Treatment in Perimenopausal Asymptomatic Women—ReplyDavid Rubinow, MD, JAMA
- Sex Differences and the Neurobiology of Affective DisordersDavid Rubinow, MD, Nature
Authored Content
- Progesterone and Plasma Metabolites in Women with and in Those Without Premenstrual Dysphoric DisorderSeptember 2018
- Progesterone and Plasma Metabolites in Women with and in Those Without Premenstrual Dysphoric DisorderSeptember 2018
- F122. The Neuronal Stem Cell Transcriptome of Premenstrual Dysphoric DisorderApril 2018
- S102. Pilot Double-Blind, Placebo-Controlled Clinical Trial of Transcranial Alternating Current Stimulation (tACS) for the Treatment of Major Depressive DisorderApril 2018
- S100. Efficacy and Safety of Brexanolone IV Across Phase 2/3 Studies: A First-in-Class GABAA Receptor Positive Allosteric Modulator for Postpartum DepressionApril 2018
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Press Mentions
FDA Grants Breakthrough Device Designation for Non-Invasive Brain Stimulation Device to Treat Major Depressive DisorderMarch 10th, 2025- Personalized Brain Stimulation Significantly Decreases Depression SymptomsAugust 27th, 2024
FDA Approves ZULRESSO™ (Brexanolone) Injection for Postpartum Depression Following Three Clinical Trials Led by UNC ResearcherMarch 20th, 2019- Join now to see all
Grant Support
- Postdoctoral Training in Reproductive Mood DisordersUNIV OF NORTH CAROLINA CHAPEL HILL2012–2028
- Stress-stimulated immune profiles and cardiometabolic risk during the menopausal transitionUNIV OF NORTH CAROLINA CHAPEL HILL2022–2025
- Depression, Estrogen Replacement, And Cardiovascular Health In The PerimenopauseNational Institute Of Mental Health2010–2012
- Continuous OC Treatment In PMDD: Steroid Hormone MechanismsNational Institute Of Mental Health2008–2011
- Menstrually Related Mood Disorders Screening ProtocolNational Center For Research Resources2008
- Sex Dimorphisms/Gonadal Steroid Effect--NeuroregulationNational Institute Of Mental Health2005
- Reproductive Endocrine Related Mood DisordersNational Institute Of Mental Health2003–2005
- Neuroregulation: Sexual Dimorphisms And Gonadal SteroidsNational Institute Of Mental Health2004
- Reproductive Endocrine Related Mood Disorders--DifferentNational Institute Of Mental Health2001–2004
- Sexual Dimorphisms &Gonadal Steroid Effects On NeuroregNational Institute Of Mental Health2001–2003
- Sexual Dimorphisms &Gonadal Steroid Effects On Neuroregulation/NeurodevelopmentNational Institute Of Mental Health1997–2000
- Reproductive Endocrine Related Mood Disorders--Differential SensitivityNational Institute Of Mental Health1997–2000
- Sexual Dimorphisms &Amp;Gonadal Steroid Effects On Neuroregulation/NeurodevelopmNational Institute Of Mental Health1998
- Psychobiology And Treatment Of Menstrually Related Mood DisordersNational Institute Of Mental Health1997
- Psychobiology And Treatment Of Menstrually-Related Mood DisordersNational Institute Of Mental Health1996
- Psychobiology And Treatment Of Peri-Menopausal Mood DisordersNational Institute Of Mental Health1991–1995
- Psychobiology And Treatment Of Peri-Menopausal DisordersNational Institute Of Mental Health1990
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