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Office
Visterra, Inc.
275 2nd Avenue
Waltham, MA 02451Phone+1 617-401-2026
Summary
- I am a Board Certified Infectious Disease Physician. After 18 years on faculty at the University of Maryland School of Medicine/Institute of Human Virology, I moved into drug development. First as Director in Clinical Development at Gilead (HCV/HBV), then as CMO at Cempra (antibiotics), currently as CMO at Visterra, an MIT-spinout monoclonal antibody developer (and now an Otsuka subsidiary). Visterra's focus is on developing better biologics for diseases of inflammation and immunity, focused principally on kidney disease, also with ongoing programs in selected infectious diseases.
Education & Training
Johns Hopkins UniversityFellowship, Infectious Disease, 1989 - 1992
Massachusetts General HospitalResidency, Internal Medicine, 1986 - 1989
University of Maryland School of MedicineClass of 1986
Certifications & Licensure
MD State Medical License 1989 - 2025- American Board of Internal Medicine Internal Medicine
Clinical Trials
- Evaluation of the Safety, Tolerability, Pharmacokinetics, and Activity of GS-9450 in Subjects With Chronic HCV Start of enrollment: 2008 Apr 01
- Efficacy and Safety Study of Oral Solithromycin (CEM-101) Compared to Oral Moxifloxacin in Treatment of Patients With Community-Acquired Bacterial Pneumonia Start of enrollment: 2012 Dec 01
Publications & Presentations
PubMed
- 25 citationsSafety, Tolerability, Pharmacokinetics, and Pharmacodynamics of VIS649 (Sibeprenlimab), an APRIL-Neutralizing IgGMonoclonal Antibody, in Healthy Volunteers.Mohit Mathur, Jonathan Barratt, Yusuke Suzuki, Frank Engler, Marcela F Pasetti
Kidney International Reports. 2022-05-01 - 916 citationsDeterminants of Viral Clearance and Persistence during Acute Hepatitis C Virus InfectionRobert Thimme, David W. Oldach, Kyong-Mi Chang, Carola Steiger, Stuart C. Ray
The Journal of Experimental Medicine. 2001-11-19 - 112 citationsRetention of transcriptionally active cryptophyte nuclei by the ciliate Myrionecta rubra.Matthew D. Johnson, David W. Oldach, Charles F. Delwiche, Diane K. Stoecker
Nature. 2007-01-25
Press Mentions
Visterra Presents Data Demonstrating Safety, Tolerability and Positive Clinical Activity Trends of VIS410 in Non-Hospitalized Patients with Influenza ANovember 15th, 2018- Visterra Initiates Phase 1 Clinical Study of VIS649November 8th, 2018
- Visterra to Present New Preclinical Data on VIS410 for Influenza A at the International Meeting on Respiratory PathogensMarch 7th, 2018
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Grant Support
- Needlestick HCV Exposure: Virologic &Immunologic EventsNational Institute Of Allergy And Infectious Diseases2000–2003
- Needlestick HCV Exposure--Virologic &Immunologic EventsNational Institute Of Allergy And Infectious Diseases1999
- Needlestick HCV Exposure Among Health Care WorkersNational Institute Of Allergy And Infectious Diseases1998–1999
- Murine Model For Hepatitis C Virus InvestigationsNational Institute Of Allergy And Infectious Diseases1996–1998
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