DavidJonMillerMDPhD

PubMed

• 1 citations
  Synthesis and biological activity of conformationally restricted indole-based inhibitors of neurotropic alphavirus replication: Generation of a three-dimensional pharm...
  Scott J. Barraza, Janice A. Sindac, Craig J. Dobry, Philip C. Delekta, Pil H. Lee
  Bioorganic & Medicinal Chemistry Letters. 2021-06-04
• 99 citations
  Heat Shock Proteins Regulatory Role in Neurodevelopment.
  David J. Miller, Patrice Fort
  Frontiers in Neuroscience. 2018-11-12
• 6 citations
  The combined use of alphavirus replicons and pseudoinfectious particles for the discovery of antivirals derived from natural products.
  Phillip C. Delekta, Avi Raveh, Martha J. Larsen, Pamela J. Schultz, Giselle Tamayo-Castillo
  Journal of Biomolecular Screening. 2015-06-01

Journal Articles

• The Combined Use of Alphavirus Replicons and Pseudoinfectious Particles for the Discovery of Antivirals Derived from Natural Products  
  Delekta, P.C., Raveh, A., Larsen, M.J., Sherman, D.H., and Miller, D.J., J. Biomolec. Screen, 1/1/2015
• Discovery of Anthranilamides as a Novel Class of Inhibitors of Neurotropic Alphavirus Replication  
  Barraza, S.J., Delekta, P.C., Sindac, J.A., Dobry, C.J., Xiang, J., Kirchhoff, P.D., Keep, R.F., Miller, D.J., and Larsen, S.D., Bioorg. Med. Chem, 1/1/2015
• Manipulation of Host Factors Optimizes the Pathogenesis of Western Equine Encephalitis Virus Infections in Mice for Antiviral Drug Development  
  Blakely, P.K., Delekta, P.C., Miller, D.J., and Irani, D.N., J. Neurovirol, 1/1/2015
• Novel Indole-2-carboxamide Compounds Are Potent Broad Spectrum Antivirals Active against Western Equine Encephalitis Virus in Vivo  
  Delekta, P.C., Dobry, C.J., Sindac, J.A., Barraza, S.J., Blakely, P.K., Xiang, J., Kirchhoff, P.D., Keep, R.F., Irani, D.N., Larsen, S.D., and Miller, D.J., J. Virol, 1/1/2014
• Discovery of Alphavirus Inhibitors Derived from Natural Products  
  Delekta, P.C., Raveh, A., Sherman, D.H., and Miller, D.J., Curr Topics Virology, 1/1/2013
• Neurotropic Arboviruses Induce Interferon Regulatory Factor 3-mediated Neuronal Responses That Are Cytoprotective, Interferon-independent, and Inhibited by Western Equ...  
  Peltier, D.C., Lazear, H.M., Farmer, J.R., Diamond, M.S., and Miller, D.J., J. Virol, 1/1/2013
• Activation of the Type I Interferon Pathway Is Enhanced in Response to Human Neuronal Differentiation  
  Farmer, J.R., Altschaefl, K.M., O'Shea, K.S., and Miller, D.J., PLoS One, 1/1/2013
• Optimization of Novel Indole-2-carboxamide Inhibitors of Neurotropic Alphavirus Replication  
  Sindac, J.A., Barraza, S.J., Dobry, C.J., Xiang, J., Blakely, P.K., Irani, D.N., Keep, R.F., Miller, D.J., and Larsen, S.D., J. Med. Chem, 1/1/2013
• Discovery of Potent Broad Spectrum Antivirals Derived from Marine Actinobacteria  
  Raveh, A., Delekta, P.C., Dobry, C.J., Peng, W., Schultz, P.J., Blakely, P.K., Tai, A.W., Matainaho, T., Irani, D.N., Sherman, D.H., and Miller, D.J., PLoS One, 1/1/2013
• Novel Inhibitors of Neurotropic Alphavirus Replication That Improve Host Survival in a Mouse Model of Acute Viral Encephalitis  
  Sindac, J., Yestrepsky, B.D., Bolduc, K.L., Barraza, S.J., Bolduc, K.L, Blakely, P.K., Keep, R.F., Irani, D.N., Miller, D.J., and Larsen, S.D., J. Med. Chem., 1/1/2012
• MDA5 and TLR3 Initiate Pro-inflammatory Signaling Pathways Leading to Rhinovirus-induced Airway Inflammation and Hyperresponsiveness  
  Wang, Q, Miller, D.J., Bowman, E.R., Nagarkar, D.R., Schneider, D., Zhao, Y., Linn, M.J., Goldsmith, A.M., Bentley, J.K., Sajjan, U.S., Colonna, M., and Hershenson, M.B., PLoS Pathog, 1/1/2011
• Role of Cellular Lipids in Positive-sense RNA Virus Replication Complex Assembly and Function  
  Stapleford, K.A. and Miller, D.J., Viruses, 1/1/2010
• Human Neuronal Cells Possess Functional Cytoplasmic and Toll-like Receptor-mediated Innate Immune Pathways Influenced by Phosphatidylinositol-3 Kinase Signaling  
  Peltier, D.C., Simms, A., Farmer, J.R., and Miller, D.J., J. Immunol, 1/1/2010
• Complementary Transcriptomic, Lipidomic, and Targeted Functional Genetic Analyses in Cultured Drosophila Cells Highlight the Role of Glycerophospholipid Metabolism in ...  
  Castorena, K.M., Stapleford, K.A., and Miller, D.J., BMC Genomics, 1/1/2010
• Restriction of Rift Valley Fever Virus Virulence in Mosquito Cells  
  Vaughn, V.M., Streeter, C.C., Miller, D.J., and Gerard, S.R., Viruses, 1/1/2010
• A Targeted Analysis of Cellular Chaperones Reveals Contrasting Roles for Heat Shock Protein 70 in Flock House Virus RNA Replication  
  Weeks, S.A., Shield, W.P., Sahi, C., Craig, E.A., Rospert, S., and Miller, D.J., J. Virol, 1/1/2010
• Role of Double-stranded RNA Pattern Recognition Receptors in Rhinovirus-induced Airway Epithelial Cell Responses  
  Wang, Q., Nagarkar, D.R., Bowman, E.R., Schneider, D., Gosangi, B., Lei, J., Zhao, Y., McHenry, C.L., Burgens, R.V., Miller, D.J., Sajjan, U., and Hershenson, M.B., J. Immunol, 1/1/2009
• Mitochondrion-enriched Anionic Phospholipids Facilitate Flock House Virus RNA Polymerase Membrane Association  
  Stapleford, K.A., Rapaport, D., and Miller, D.J., J. Virol., 1/1/2009
• The Identification of Thieno [3,2-b]pyrrole Derivatives as Novel Small Molecule Inhibitors of Neurotropic Alphaviruses  
  Peng, W., Peltier, D.C., Larsen, M.J., Kirchhoff, P.D., Larsen, S.D., Neubig, R.R., and Miller, D.J., J. Infect. Dis., 1/1/2009
• The Heat Shock Protein 70 Co-chaperone YDJ1 Is Required for Membrane-specific Flock House Virus RNA Replication Complex Assembly and Function in Saccharomyces Cerevisiae  
  Weeks, S.A. and Miller, D.J., J. Virol, 1/1/2008
• A Functional Heat Shock Protein 90 Chaperone Is Essential for Efficient Flock House Virus RNA Polymerase Synthesis in Drosophila Cells  
  Castorena, K.M., Weeks, S.A., Stapleford, K.A., Cadwallader, A.M., and Miller, D.J., J. Virol, 1/1/2007
• Three-dimensional Analysis of a Viral RNA Replication Complex Reveals a Virus-induced Mini-organelle  
  Kopek, B.G., Perkins, G., Miller, D.J., Ellisman, M.H., and Ahlquist, P., PLoS Biology, 1/1/2007
• In Vivo Self-interaction of Nodavirus RNA Replicase Protein a Revealed by Fluorescence Resonance Energy Transfer  
  Dye, B.T., Miller, D.J., and Ahlquist, P., J. Virol, 1/1/2005
• The Cellular Chaperone Heat Shock Protein 90 Facilitates Flock House Virus RNA Replication in Drosophila Cells  
  Kampmueller, K.M. and Miller, D.J., J. Virol, 1/1/2005
• Detecting Protein-protein Interactions in Live Yeast by Flow Cytometry  
  Dye, B.T., Schell, K., Miller, D.J., and Ahlquist, P, Cytometry, 1/1/2005
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Books/Book Chapters

• Cell Biology and Pathology of Myelin 
  Chapter: The Repair of Central Nervous System Myelin. Cell Biology and Pharmacologic Action of Remyelination-promoting Autoantibodies 
  Page 253.0 - 264.0Hunter, S.F., Asakura, K., Miller, D.J., and Rodriguez, M.Editors: Juurlink et al.Plenum Press, New York1997