DavidCLinehanMD

PubMed

• Integrating IL-12 mRNA nanotechnology with SBRT eliminates T cell exhaustion in preclinical models of pancreatic cancer.
  Angela L Hughson, Gary Hannon, Noah A Salama, Tara G Vrooman, Caroline A Stockwell
  Molecular Therapy. Nucleic Acids. 2024-12-10
• Supporting Surgeon-Scientists to Prosper as Researchers.
  Jennifer E B Harman, David C Linehan, Anusha Naganathan
  JAMA Surgery. 2024-12-01
• 1 citations
  Platelet-activating factor (PAF) promotes immunosuppressive neutrophil differentiation within tumors.
  Ankit Dahal, Yeonsun Hong, Jocelyn S Mathew, Adam Geber, Sarah Eckl
  Proceedings of the National Academy of Sciences of the United States of America. 2024-08-27

Journal Articles

• Germline Cancer Susceptibility Gene Variants, Somatic Second Hits, and Survival Outcomes in Patients with Resected Pancreatic Cancer  
  Richard F Dunne, Leona A Doyle, William C Hahn, Jason L Hornick, Andrea J Bullock, Sapna Syngal, Albert C Koong, Natalia Khalaf, Brian M Wolpin, Douglas A Rubinson, Da..., Nature
• Histological features and severity of oxaliplatin-induced liver injury and clinical associations  
  Nalbantoglu I; Tan BR; Linehan DC; Gao F; Brunt EM, Journal of Digestive Diseases, 1/1/2014
• CSF1/CSF1R blockade reprograms tumor-infiltrating macrophages and improves response to T-cell checkpoint immunotherapy in pancreatic cancer models  
  Zhu Y; Knolhoff BL; Meyer MA; Nywening TM; West BL; Luo J; Wang-Gillam A; Goedegebuure SP; Linehan DC; DeNardo DG, Cancer Research, 1/1/2014
• Variations in definition and method of retrieval of complications influence outcomes statistics after pancreatoduodenectomy: comparison of NSQIP with non-NSQIP methods  
  Sanford DE; Woolsey CA; Hall BL; Linehan DC; Hawkins WG; Fields RC; Strasberg SM, Journal of the American College of Surgeons, 1/1/2014
• Natural History of Preoperative Subcentimeter Pulmonary Nodules in Patients With Resectable Pancreatic Adenocarcinoma: A Retrospective Cohort Study  
  Chang ST; Nguyen DC; Raptis C; Menias CO; Zhou G; Wang-Gillam A; Linehan DC; Hawkins WG; Strasberg SM; Fields RC, Annals of Surgery, 1/1/2014
• Tumor-induced STAT3 activation in monocytic myeloid-derived suppressor cells enhances stemness and mesenchymal properties in human pancreatic cancer  
  Panni RZ; Sanford DE; Belt BA; Mitchem JB; Worley LA; Goetz BD; Mukherjee P; Wang-Gillam A; Link DC; Denardo DG; Goedegebuure SP; Linehan DC, Cancer immunology, immunotherapy, 1/1/2014
• A new operative approach for type I choledochal cysts  
  Jin LX; Fields RC; Hawkins WG; Linehan DC; Strasberg SM, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 1/1/2014
• Regional lymphadenectomy is indicated in the surgical treatment of pancreatic neuroendocrine tumors (PNETs)  
  Hashim YM; Trinkaus KM; Linehan DC; Strasberg SS; Fields RC; Cao D; Hawkins WG, Annals of surgery, 1/1/2014
• Jaundice: an important, poorly recognized risk factor for diminished survival in patients with adenocarcinoma of the head of the pancreas  
  Strasberg SM; Gao F; Sanford D; Linehan DC; Hawkins WG; Fields R; Carpenter DH; Brunt EM; Phillips C, HPB : the official journal of the International Hepato Pancreato Biliary Association, 1/1/2014
• Down-regulation of PLCGamma2-Beta-catenin pathway promotes activation and expansion of myeloid-derived suppressor cells in cancer  
  Capietto AH; Kim S; Sanford DE; Linehan DC; Hikida M; Kumosaki T; Novack DV; Faccio R, The Journal of experimental medicine, 1/1/2013
• Targeting tumor-infiltrating macrophages decreases tumor-initiating cells, relieves immunosuppression, and improves chemotherapeutic responses  
  Mitchem JB; Brennan DJ; Knolhoff BL; Belt BA; Zhu Y; Sanford DE; Belaygorod L; Carpenter D; Collins L; Piwnica-Worms D; Hewitt S; Udupi GM; Gallagher WM; Wegner C; Wes..., Cancer Research, 1/1/2013
• Cost benefit analysis of mesh reinforcement of stapled left pancreatectomy  
  Idrees K; Edler JR; Linehan DC; Strasberg SM; Jacques D; Hamilton NA; Fields RC; Lambert D; Kymes S; Hawkins WG, HPB : the official journal of the International Hepato Pancreato Biliary Association, 1/1/2013
• Colorectal liver metastases: state of the art imaging  
  Fowler KJ; Linehan DC; Menias CO, Annals of Surgical Oncology, 1/1/2013
• Inflammatory monocyte mobilization decreases patient survival in pancreatic cancer: a role for targeting the CCL2/CCR2 axis  
  Sanford DE; Belt BA; Panni RZ; Mayer A; Deshpande AD; Carpenter D; Mitchem JB; Plambeck-Suess SM; Worley LA; Goetz BD; Wang-Gillam A; Eberlein TJ; Denardo DG; Goedegeb..., Clinical cancer research : an official journal of the American Association for Cancer Research, 1/1/2013
• Pancreatic adenocarcinoma induces bone marrow mobilization of myeloid-derived suppressor cells which promote primary tumor growth  
  Porembka MR; Mitchem JB; Belt BA; Hsieh CS; Lee HM; Herndon J; Gillanders WE; Linehan DC; Goedegebuure P, Cancer immunology, immunotherapy, 1/1/2012
• Long-term results of resection of adenocarcinoma of the body and tail of the pancreas using radical antegrade modular pancreatosplenectomy procedure  
  Mitchem JB; Hamilton N; Gao F; Hawkins WG; Linehan DC; Strasberg SM, Journal of the American College of Surgeons, 1/1/2012
• The right way to do a Whipple procedure: comment on 'Stenting and the rate of pancreatic fistula following pancreaticoduodenectomy'  
  Linehan, DC, Archives of Surgery, 1/1/2012
• Pattern of lymph node involvement and prognosis in pancreatic adenocarcinoma: direct lymph node invasion has similar survival to node-negative disease  
  Pai RK; Beck AH; Mitchem J; Linehan DC; Chang DT; Norton JA; Pai RK, The American journal of surgical pathology, 1/1/2011
• Choosing 'The Best'  
  Linehan, DC; Jaques D, Archives of Surgery, 1/1/2011
• Myeloid-derived suppressor cells: general characteristics and relevance to clinical management of pancreatic cancer  
  Goedegebuure P; Mitchem JB; Porembka MR; Tan MC; Belt BA; Wang-Gillam A; Gillanders WE; Hawkins WG; Linehan DC, Current Cancer Drug Targets, 1/1/2011
• A technique of gastrojejunostomy to reduce delayed gastric emptying after pancreatoduodenectomy  
  Khan AS; Hawkins WG; Linehan DC; Strasberg SM, Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 1/1/2011
• Radiologic and intraoperative detection of need for mesenteric vein resection in patients with adenocarcinoma of the head of the pancreas  
  Porembka MR; Hawkins WG; Linehan DC; Gao F; Ma C; Brunt EM; Strasberg SM, HPB : the official journal of the International Hepato Pancreato Biliary Association, 1/1/2011
• Induction of Th17 cells in the tumor microenvironment improves survival in a murine model of pancreatic cancer  
  Gnerlich JL; Mitchem JB; Weir JS; Sankpal NV; Kashiwagi H; Belt BA; Porembka MR; Herndon JM; Eberlein TJ; Goedegebuure P; Linehan DC, The Journal of immunology : official journal of the American Association of Immunologists, 1/1/2010
• Bile duct injuries in the era of laparoscopic cholecystectomies  
  Wu YV; Linehan DC, The Surgical clinics of North America, 1/1/2010
• Cancer causes increased mortality and is associated with altered apoptosis in murine sepsis  
  Fox AC; Robertson CM; Belt B; Clark AT; Chang KC; Leathersich AM; Dominguez JA; Perrone EE; Dunne WM; Hotchkiss RS; Buchman TG; Linehan DC; Coopersmith CM, Critical care medicine, 1/1/2010
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Books/Book Chapters

• Surgery of the Liver, Biliary Tract and Pancreas. 
  Linehan DC and Jarnagin WREditors: Blumgart LH.Elsevier, Philadelphia, PA2007
• Malignant Liver Tumors: Current and Emerging Therapies. 
  Chapter: Thermal Ablation of Liver Tumors by Radiofrequency, Microwave, and Laser Therapy. 
  Strasberg SM and Linehan DCBartlett and Barnes, Chicago, IL2002
• Surgical Research. 
  Chapter: Active Immunotherapy. 
  Souba WW and Wilmore, DWAcademic Press, San Diego, CA2001
• Surgical Treatment: Evidence-Based and Problem Oriented 
  Chapter: Soft Tissue Sarcoma. 
  Linehan DC and Brennan MFW Zuckschwerdt Verlag, Munich, Germany2001
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Other

• Tumors of the Liver, Biliary Tract and Pancreas. 
  Strasberg SM and Linehan DC, ACS Surgery Online: Principles & Practice, Souba WW, Fink MP, Jurkovich et al, Eds. WebMD, Inc.
  http://www.acssurgery.com
  1/1/2005