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Office
120 Harmony Ct
Santa Cruz, CA 95062Phone+1 650-721-1300Fax+1 650-646-9199
Summary
- Dr. David Karpf is an experienced endocrinologist based in Palo Alto, CA with subspecialties in diabetes, lipid metabolism, osteoporosis, and bone metabolism medicine. He completed his fellowships in Endocrinology, Diabetes, and Metabolism at UCLA-VA Greater Los Angeles and Cedars-Sinai Medical Center, after his residency at the latter institution and gaining his medical degree from The University of California San Diego School of Medicine. He then undertook an elective 3rd year of fellowship to gain additional experience in metabolic bone diseases at the Endocrine Unit at UC San Francisco School of Medicine. Following 5 years on the UCSF Endocrine Faculty, Dr. Karpf was recruited to Merck to Merck & Co, Inc., to designed and run the Phase 3 fracture endpoint trials with Fosamax. Following the launch of Fosamax, Dr. Karpf was recruited to Roche based in Palo Alto, to initially work on an anabolic osteoporosis drug and then to run the Phase 3 fracture endpoint trials for both oral and IV Boniva. In 1997 Dr. Karpf joined the Stanford Endocrine Faculty, where he currently serves as Adjunct Clinical Professor of Endocrinology, Gerontology, and Metabolism at Stanford University School of Medicine, and Attending, Osteoporosis & Metabolic Bone Disease Clinic. He has a rich publication history, including influential work on osteoporosis, growth hormone deficiency and hypoparathyroidism. He has also participated in multiple clinical trials in related areas. His contributions have been recognized with numerous awards such as the Fellow from ASBMR in 2020 and the NIH FIRST Award in 1991.
Education & Training
- UCLA-VA Greater Los AngelesFellowship, Endocrinology, Diabetes, and Metabolism, 1984 - 1985
- Cedars-Sinai Medical CenterFellowship, Endocrinology, Diabetes, and Metabolism, 1983 - 1985
- Cedars-Sinai Medical CenterResidency, Internal Medicine, 1980 - 1983
- University of California San Diego School of MedicineClass of 1980
Certifications & Licensure
- CA State Medical License 1981 - 2026
- NJ State Medical License 1996 - 1997
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Fellow ASBMR, 2020
- NIH FIRST Award NIH, 1991
- Merit Review Award, VAMC-SF VA, 1989
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Clinical Trials
- A Phase 3 Trial of the Safety, Tolerability and Efficacy of TransCon hGH Weekly Versus Daily hGH in Children With Growth Hormone Deficiency (GHD) Start of enrollment: 2016 Dec 13
- A Safety, Tolerability and Efficacy Study of TransCon hGH in Children With Growth Hormone Deficiency Start of enrollment: 2017 Nov 13
- A Long-Term Trial Investigating Safety and Efficacy of TransCon hGH in Children With Growth Hormone Deficiency Who Have Completed a Prior TransCon hGH Clinical Trial Start of enrollment: 2017 Dec 19
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Publications & Presentations
PubMed
- Response to Letter to the Editor From Malozowski: "Weekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial".Paul S Thornton, Aristides K Maniatis, Elena Aghajanova, Elena Chertok, Zhengning Lin
The Journal of Clinical Endocrinology and Metabolism. 2022-04-19 - Response to Letter to the Editor From L. Sävendahl et al: "Weekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial".Paul S Thornton, Aristides K Maniatis, Elena Aghajanova, Elena Chertok, Elpis Vlachopapadopoulou
The Journal of Clinical Endocrinology and Metabolism. 2022-02-17 - 28 citationsWeekly Lonapegsomatropin in Treatment-Naïve Children With Growth Hormone Deficiency: The Phase 3 heiGHt Trial.Paul S. Thornton, Aristides K Maniatis, Elena Aghajanova, Elena Chertok, Elpis Vlachopapadopoulou
The Journal of Clinical Endocrinology and Metabolism. 2021-10-21
Press Mentions
- Lumos Pharma Reports First Quarter 2023 Financial Results, Provides Clinical UpdatesMay 3rd, 2023
- CEO Update: Interview with Lumos Pharma's Chief Medical Officer, David B. Karpf, M.D.July 26th, 2022
- Lumos Pharma, Inc. (LUMO) CEO Richard Hawkins on Q1 2022 Results - Earnings Call TranscriptMay 11th, 2022
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Professional Memberships
- Member
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