DavidHoytema van KonijnenburgMDPhD

Pediatric Asthma & Allergic Conditions, Clinical & Laboratory Immunology

Attending Physician in Allergy and Immunology

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MD PhD, completed PhD work in Immunology at Utrecht University, Van Wijk lab and The Rockefeller University, Mucida lab. My research focused on intestinal T cells using a combination of techniques including live imaging. Completed pediatrics residency at Boston Childrens Hospital and Harvard Medical School concurrent with research at Harvard Medical School, Kirchhausen lab, Zon lab, where I studied the development and function of tissue-resident immune cells whilst completing the Integrated Research Pathway.
Current Allergy and Immunology Attending Physician at Boston Children's Hospital and Instructor at Harvard Medical School, working in Nigrovic lab and Zanoni lab on tissue-resident immune cells in the lung. Clinically especially passionate about providing care for patients with immune dysregulation syndromes or immunodeficiency, with a focus on immunogenetics and research-based clinical care for patients with rare diseases of the immune system. Part of MIDAS Immune Dysregulation program and Interstitial Lung Diseases program at Boston Children's Hospital.

Boston Children’s HospitalFellowship, Allergy and Immunology, 2021 - 2024
Boston Children’s Hospital/Boston Medical CenterResidency, Pediatrics, 2018 - 2021
Utrecht University Graduate School of Life SciencesPhD, Immunology, Cum Laude, 2015 - 2018
Utrecht University Faculty of MedicineClass of 2014, MD, Cum Laude

Paul A. Dobuler Prize for Excellence in Immunodeficiency Research Paul A. Dobuler Memorial Research Fund, 2024
Fellow Teaching Honor Roll Boston Combined Residency in Pediatrics, 2022-2023
Bravo! Way to Shine Star Award Boston Children's Hospital, 2022
Chrysalis Project participant American Academy of Allergy, Asthma & Immunology (AAAAI), 2021
House Staff Development Award Medical Staff Organization, Boston Children's Hospital, 2020
Fred Lovejoy Resident Research Award Boston Children’s Hospital, 2020
Trainee Travel Award for Excellence Alumni Association, Boston Children's Hospital, 2020
PhD Thesis Award Pediatrics Association of the Netherlands (NVK), Section on Infection & Immunity, 2018
Travel Grant Federation of Clinical Immunology Societies (FOCIS), 2015
Talma Eykman Thesis Award in Medicine, Biomedical Sciences or Health Sciences University Medical Center Utrecht, 2015
National Prize for "best medical student" The Professor Chris Gips Foundation for Young Scientific Talent, 2015
MSc Honors Program in Medicine Utrecht University, 2011-2014
Student Research Award Dutch Digestive Foundation, 2013
BSc Honors Program in Medicine Utrecht University, 2008-2010
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PubMed

94 citations
Vasculature-associated fat macrophages readily adapt to inflammatory and metabolic challenges
Hernandez Moura Silva, André Báfica, Gabriela F. Rodrigues-Luiz, Jingyi Chi, Patricia d’Emery Alves Santos
The Journal of Experimental Medicine. 2019-04-01
168 citations
Tissue adaptation of regulatory and intraepithelial CD4 + T cells controls gut inflammation
Tomohisa Sujino, Mariya London, David P. Hoytema van Konijnenburg, Tomiko Rendon, Thorsten Buch
Science. 2016-06-24
20 citations
Intraepithelial lymphocytes.
David P Hoytema van Konijnenburg, Daniel Mucida
Current Biology. 2017-08-07

An unexpected origin for calming immune cells in the gutMarch 19th, 2021
In brief: Immune cells surveil intestine to prevent infectionsMarch 19th, 2021
https://www.umcutrecht.nl/en/about-us/news/details/jun-8-special-immune-cells-in-the-intestinal-wall-play-a-role-in-chronic-intestinal-inflammationsMarch 19th, 2021
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Resetting regulatory T cell networks in Inflammatory Bowel DiseaseUniversity Medical Center Utrecht - Career Development - Alexandre Suerman MD/PhD Stipend (internal)2015–2018
Intestinal Surveillance, Regulation and Recovery by Intraepithelial LymphocytesPrince Bernhard Cultural Foundation - Career Development - Grant2016–2017
Intestinal Surveillance, Regulation and Recovery by Intraepithelial LymphocytesRoyal Netherlands Academy of Arts and Sciences - Career Development – Academy Ter Meulen Grant2016–2017
Intestinal Surveillance by Intraepithelial LymphocytesHelmsley Charitable Trust / The Rockefeller University - Research - Pilot Project Award (internal)2014–2015

LinkedIn Profilehttps://www.linkedin.com/in/davidhoytema/
Harvard Catalyst Profilehttps://connects.catalyst.harvard.edu/Profiles/display/Person/169292
Boston Children's Profilehttps://www.childrenshospital.org/directory/david-hoytema-van-konijnenburg