DavidMarshallGuidotMD

PubMed

• Ethanol-exposed lung fibroblasts cause airway epithelial barrier dysfunction.
  Viranuj Sueblinvong, Xian Fan, Craishun Hart, Samuel Molina, Michael Koval
  Alcohol, Clinical & Experimental Research. 2023-10-01
• 3 citations
  MYOSIN LIGHT CHAIN KINASE DELETION WORSENS LUNG PERMEABILITY AND INCREASES MORTALITY IN PNEUMONIA-INDUCED SEPSIS.
  Deena B Chihade, Prestina Smith, David A Swift, Shunsuke Otani, Wenxiao Zhang
  Shock. 2023-04-01
• 3 citations
  Alcohol impairs recognition and uptake of Mycobacterium tuberculosis by suppressing toll-like receptor 2 expression.
  Gregory W Wigger, Darya Khani, Mariam Ahmed, Layal Sayegh, Sara C Auld
  Alcoholism, Clinical and Experimental Research. 2022-12-01

Journal Articles

• Alveolar barrier function in alcoholic lung syndrome is impaired by tight junction destabilization  
  Schlingmann BL, Ward C, Molina SA, Overgaard CE, Guidot DM, Koval M, Ann Am Thorac Soc, 1/1/2015
• Donor alcohol abuse and lung injury following allograft transplantation: a cautionary tale but also a call to action  
  Guidot DM, Alcoholism: Clin Exp Res, 1/1/2014
• Presentation of the 2014 Founder's Medal Award  
  Guidot, D.M., Am J Med Sci, 1/1/2014
• Chronic Alcohol Ingestion in Rats Decreases Krüppel-Like Factor 4 Expression and Intracellular Zinc in the Lung  
  Curry-McCoy TV, Guidot DM, Joshi PC, Alcoholism: Clin Exp Res, 1/1/2013
• Nicotinic Acetylcholine Receptors are Sensors for Ethanol in Lung Fibroblasts  
  Ritzenthaler JD, Roser-Page S, Guidot DM, Roman J., Alcoholism: Clin Exp Res, 1/1/2013
• Alcohol ingestion disrupts alveolar epithelial barrier function by activation of macrophage-derived transforming growth factor beta1  
  Curry-McCoy TV, Venado A, Guidot DM, Joshi PC., Respir Res, 1/1/2013
• Alcohol causes alveolar epithelial oxidative stress by inhibiting the Nrf2/ARE signaling pathway  
  Jensen, JS, Fan X and Guidot, DM, American Journal of Respiratory Cell Molecular Biology, 1/1/2013
• Recruitment and retention in academic medicine--what junior faculty and trainees want department chairs to know  
  Kubiak NT, Guidot DM, Trimm RF, Kamen DL, Roman J, Am J Med Sci, 1/1/2012
• Alcohol abuse, the alveolar macrophage, and pneumonia  
  Mehta AJ and Guidot, DM, American Journal of the Medical Sciences, 1/1/2012
• HIV-1 transgene expression in rats induces differential expression of tumor necrosis factor alpha and zinc transporters in the liver and the lung  
  Joshi PC and Guidot DM, AIDS Research & Therapy, 1/1/2011
• Chronic alcohol ingestion exacerbates lung epithelial barrier dysfunction in HIV-1 transgenic rats  
  Fan, X., Joshi, P,C., Koval, M. and Guidot, D.M., Alcoholism: Clin Exp Res, 1/1/2011
• Zinc supplementation restores PU1 and Nrf2 nuclear binding in alveolar macrophages and improves redox balance and bacterial clearance in the lungs of alcohol-fed rats  
  Mehta, A.J., Joshi, P.C., Fan, X, Brown, L.S., Ritzenthaler, J.D., Roman, J. and Guidot, D.M., Alcoholism: Clin Exp Res, 1/1/2011
• Lung Disease and HIV/AIDS in the HAART Era  
  Morris, A. and Guidot, D.M., Future Medicine - HIV Therapy, 1/1/2010
• Modeling HIV and Alcohol’s Effects: Focus on the Lung  
  Quintero D. and Guidot, D.M., Alcohol Research & Health, 1/1/2010
• Procysteine increases alcohol-depleted glutathione stores in rat plantaris following a period of abstinence  
  Otis, J.S. and Guidot, D.M., Alcohol, 1/1/2010
• Alterations in the immuno-skeletal interface drive bone destruction in HIV-1 transgenic rats  
  Vikulina T., Fan, X., Yamaguchi, M., Roser-Page S., Zayzafoon, M., Guidot, D.M., Ofotokun, I. and Weitzman, M.N., Proc Natl Acad Sci USA, 1/1/2010
• HIV-1 transgene expression in rats causes oxidant stress and alveolar epithelial barrier dysfunction  
  Lassiter, C., Fan, X., Joshi, P.C., Jacob, B.A., Sutliff, R.L., Jones, D.P., Koval, M. and Guidot, D.M., AIDS Research & Therapy, 1/1/2009
• Alcohol primes the airway for increased interleukin-13 signaling  
  Mitchell. P.O., Jensen, J.S., Ritzenthaler, J.D., Roman, J., Pelaez, A. and Guidot, D.M., Alcoholism: Clin Exp Res, 1/1/2009
• Zinc deficiency mediates alcohol-induced alveolar epithelial and macrophage dysfunction in rats  
  Joshi, P.C., Mehta, A.J., Jabber, W., Fan, X., and Guidot, D.M., American Journal of Respiratory Cell and Molecular Biology, 1/1/2009
• Procysteine stimulates expression of key anabolic factors and reduces plantaris atrophy in alcohol-fed rats  
  Otis J.S. and Guidot, D.M., Alcoholism: Clin Exp Res, 1/1/2009
• Effects of Alcohol and GM-CSF on Alveolar Tight Junctions  
  Koval, M, Fan, X, Fernandez, A.L., Johnson, L.N., Joshi, P.C., Guidot, D.M., Proc Am Thorac Soc, 1/1/2008
• HIV-1 transgene expression in rats decreases alveolar macrophage zinc levels and phagocytosis  
  Joshi, P.C., Raynor, R., Fan, X., and Guidot, D.M., American Journal of Respiratory Cell and Molecular Biology, 1/1/2008
• Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration  
  Erik R. Kline, Dean J. Kleinhenz, Bill Liang, Sergey Dikalov, David M. Guidot, C. Michael Hart, Dean P. Jones and Roy L. Sutliff, Am J Physiol: Heart, 1/1/2008
• Na/K-ATPase expression is increased in the lungs of alcohol-fed rats  
  Otis, J.S., Mitchell, P.O., Kershaw, C.D., Joshi, P.C., and Guidot, D.M., Alcoholism: Clin Exp Res, 1/1/2008
• Chronic ethanol ingestion increases aortic endothelial nitric oxide synthase expression and nitric oxide production in the rat  
  Kleinhenz, D.J., Sutliff, R.L., Polikandriotis, J.A., Walp, E.R., Dikalov, S.I., Guidot, D.M. and Hart, C.M., Alcoholism: Clin Exp Res, 1/1/2008
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Books/Book Chapters

• Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach 
  Chapter: A brief history of alcohol use and abuse in human history. 
  Guidot, D.M.Editors: Mehta, AJ and Guidot, DM.Springer Science, New York, NY2013
• Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach 
  Chapter: Alcohol-mediated zinc deficiency within the alveolar space: a potential fundamental mechanism underlying oxidative stress and cellular dysfunction in the alcoholic lung. 
  Guidot, D.M. and Mehta, A.J.Editors: Mehta, AJ and Guidot, DM.Springer Science, New York, NY2013
• Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach 
  Chapter: Disruption in the dynamic balance between transforming growth factor-beta and granulocyte/macrophage colony-stimulating factor signaling within the alveolar space of the alcoholic lung: impact on epit 
  Guidot, D.M. and Mehta, A.J.Editors: Mehta, AJ and Guidot, DM.Springer Science, New York, NY2013
• Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach 
  Chapter: Overview of the evolving recognition of the health effects of excessive alcohol use over the past two centuries including the classic citations. 
  Guidot, D.M. and Mehta, A.J.Editors: Mehta, AJ and Guidot, DM.Springer Science, New York, NY2013
• Alcohol Use Disorders and the Lung: A Clinical and Pathophysiological Approach 
  Editors: Mehta, AJ and Guidot, DM.Springer Science, New York, NY2013
• Etiology and Treatment of Acute Lung Injury: From bench to bedside. Volume 336 in the NATO Science Series. 
  Chapter: Ethanol ingestion, via glutathione depletion, impairs alveolar epithelial function and renders the lung susceptible to acute injury during oxidative stress. 
  Guidot, D.M., Moss, M. and Brown, L.S.Editors: Matalon, S. and Sznajder, J.I..IOS Press, Amsterdam/ Berlin/ Oxford/ Tokyo/ Washington, DC2001
• Understanding the Process of Aging: The roles of mitochondria, free radicals, and antioxidants. 
  Chapter: Mitochondria generate and scavenge superoxide anion. 
  Guidot, D.M. and McCord J.M.Editors: Cadenas, E. and Packer, L..Marcel Dekker, Inc., New York, NY1999
• The Emory University Comprehensive Board Review in Internal Medicine. 
  Chapter: Pulmonary Diagnostic Techniques. 
  Guidot, D.M., Roman, J. and Francis, P.B.Editors: Stein, S.F. and Kokko, J.P..McGraw-Hill, New York, NY1997
• The Internal Medicine Casebook. 
  Chapter: Pleural Disease. 
  Guidot, D.M.Editors: Schrier, R.W..Little, Brown and Co., Boston/New York/Toronto/London1994
• Critical Care Secrets. 
  Chapter: AIDS in the Intensive Care Unit. 
  Guidot, D.M.Editors: Parsons, P.E., Wiener-Kronish, J.P..Hanley & Belfus, Philadelphia, PA1992
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Lectures

• When the Nrf2-ARE defenses fail: insights from studies of HIV and the alcoholic lung. 
  Medical University of South Carolina - 1/1/2014
• How to Successfully Compete For An Academic Job: What Division Directors Wants And Do Not Want in Candidates. 
  San Diego, CA - 1/1/2014
• Elucidating the Mechanisms Underlying the Alcoholic Lung: An Emory Story 
  Wake Forest University, Winston-Salem, NC - 1/1/2013
• HIV-related lung disease: a translational approach. 
  Emory University - 1/1/2013
• Immune enhancement in alcohol abuse and HIV 
  Case Western Reserve University and the Louis Stokes VA, Cleveland, OH - 1/1/2012
• The pulmonary complications of alcohol abuse: common and deadly. 
  San Francisco, CA - 1/1/2012
• The Alcoholic Lung. 
  San Francisco, CA - 1/1/2012
• Can we enhance lung health in people with alcohol use disorders and other forms of chronic oxidative stress? 
  University of Alabama at Birmingham - 1/1/2012
• Zinc and Nrf2: Getting to the source of redox stress in the alcoholic lung. 
  University of South Alabama - 1/1/2011
• Alcohol and Lung Disease: what have we learned thus far? 
  University of Louisville - 1/1/2010
• The Alcoholic Lung: A Physician’s Perspective. 
  University of Pittsburgh - 1/1/2009
• Alcohol Abuse and Pneumonia 
  Toronto, Canada - 1/1/2008
• The effects of alcohol use in the critically ill: lessons from bench to bedside. 
  San Francisco, CA - 1/1/2007
• The pulmonary complications of alcohol abuse. 
  Miami, FL - 1/1/2007
• Epithelial barrier dysfunction in the alcoholic lung: basic mechanisms and potential therapies. 
  Chicago, IL - 1/1/2007
• Alcohol and lung injury; getting the signals crossed. 
  Chicago, IL - 1/1/2007
• Alcohol abuse and lung injury. 
  Shanghai, China - 1/12/2005
• Impaired cytokine regulation renders the alcoholic lung susceptible to injury from both aberrant immune activation and immune suppression. 
  Santa Barbara, CA - 1/1/2005
• The role of GM-CSF signaling in acute lung injury. 
  Duke University - 1/1/2005
• Chronic alcohol abuse and the lung: epidemiology, toxicology, and potential new treatments. 
  University of Pennsylvania - 1/1/2004
• Alcohol and alveolar epithelial dysfunction: Implications for acute lung injury and host defense in critically ill patients. 
  Mannheim, Germany - 1/1/2004
• Transfusion therapy in the ICU. 
  Emory University - 1/1/2004
• Alcohol abuse and ARDS: Epidemiology and underlying mechanisms. 
  University of Toronto - 1/1/2004
• Novel treatments for alcohol-mediated alveolar epithelial dysfunction. 
  Washington, DC - 1/1/2004
• Transfusion therapy: evidence-based approach to a common therapy. 
  1/1/2004
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