David Hoadley Ellison MD

PubMed

• Flow-dependent transport processes 2024: filtration, absorption, secretion.
  Aurélie Edwards, Alicia A McDonough, David H Ellison
  American Journal of Physiology. Renal Physiology. 2025-03-17
• Distinct cell types along thick ascending limb express pathways for monovalent and divalent cation transport.
  Hasan Demirci, Jessica Bahena-Lopez, Alina Smorodchenko, Xiao-Tong Su, Jonathan Nelson
  Biorxiv. 2025-01-21
• 2 citations
  Mechanistic Differences between Torsemide and Furosemide.
  Veena S Rao, Zachary L Cox, Juan B Ivey-Miranda, Daniel Neville, Natasha Balkcom
  Journal of the American Society of Nephrology. 2025-01-01

Journal Articles

• Renal COP9 Signalosome Deficiency Alters cul3-klhl3-WNK Signaling Pathway  
  David Ellison, MD, Journal of the American Society of Nephrology
• The Calcium-Sensing Receptor Increases Activity of the Renal NCC Through the WNK4-SPAK Pathway  
  David Ellison, MD, Journal of the American Society of Nephrology
• Bardoxolone methyl in type 2 diabetes and advanced chronic kidney disease  
  Ellison, DH, N Engl J Med, 1/1/2014
• PharmGKB summary: Diuretics pathway, pharmacodynamics  
  Thorn CF, Ellison DH, Turner ST, Altman RB, Klein TE, Pharmacogenet Genomics, 1/1/2013
• A SPAK isoform switch modulates renal salt transport and blood pressure  
  McCormick JA, Mutig K, Nelson JH, Saritas T, Hoorn EJ, Yang CL, Rogers S, Curry J, Delpire E, Bachmann S, and Ellison DH, Cell Metabolism, 1/7/2011
• The calcineurin inhibitor tacrolimus activates the renal sodium chloride cotransporter to cause hypertension  
  Hoorn EJ, Walsh SB, McCormick JA, Furstenberg A, Yang CL, Roeschel T, Paliege A, Howie AJ, Conley J, Bachmann S, Unwin RJ, Ellison DH, SeminNephrol, 1/1/2011
• Welling PAWNK1 kinase isoform switch regulates renal potassium excretion  
  Wade JB, Fang L, Liu J, Li D, Yang CL, Subramanya AR, Maouyo D, Mason A, Ellison DH, ProcNatlAcadSci U S A, 1/30/2006
• Disorders of Sodium and Water Core Curriculum in Nephrology  
  Ellison DH, Am J Kidney Disease, 1/1/2005
• Comparison of WNK4 and WNK1 kinase and inhibiting activities  
  Wang Z, Yang CL, Ellison DH, BiochemBiophys Res Commun, 1/7/2004
• Renal expression of sodium transporters and aquaporin-2 in hypothyroid  
  Schmitt R, Klussmann E, Kahl T, Ellison DH, Bachmann S, Am J Physiol Renal Physiol, 1/1/2003
• The thiazide-sensitive Na-Cl cotransporter and human disease: reemergence of an old player  
  Ellison DH, J Am SocNephrol, 1/1/2003
• WNK kinases regulate thiazide-sensitive Na-Clcotransport  
  Yang CL, Angell J, Mitchell R, Ellison DH, J Clin Invest, 1/1/2003
• The distal convoluted tubule of the rabbit kidney does not express a functional sodium channel  
  Velazquez H, Silva T, Andujar E, Desir GV,Ellison DH, Greger R, Am. J. Physiol. Renal Physiol, 1/1/2001
• Loop Diuretic Infusion Increases Thiazide-Sensitive Na-Cl Cotransporter Expression by an Aldosterone-Dependent Mechanism  
  Abdallah JG, Schrier RW, Edelstein C, Jennings SD, Wyse B, Ellison DH, J.Am. Soc.Nephrol, 1/1/2001
• Calcium and sodium transport by the distal convoluted tubule of the rat  
  Costanzo LS, Windhager EE, Ellison DH, J Am SocNephrol, 1/1/2000
• Divalent cation transport by the distal nephron: insights from Bartter’s and Gitelman’s syndromes  
  Ellison DH, Am J Physiol Renal Physiol, 1/1/2000
• The Mammalian Distal Tubule:Physiology Pathophysiology and Molecular Anatomy  
  Reilly RF, Ellison DH, Physiological Reviews, 1/1/2000
• Developmental expression of sodium entry pathways in rat nephron  
  Schmitt R,Ellison DH, Farman N, Rossier B, Reilly RF, Reeves WB, Oberbäumer I, Tapp R, Bachmann S, Am.J.Physiol.Renal, 1/1/1999
• Sodium transport-related proteins in the mammalian distal nephron-distribution, ontogeny and functional aspects  
  Bachmann S, Bostanjoglo M, Schmitt R,Ellison DH, Anat. Embryol, 1/1/1999
• Diuretic Resistance: Physiology and Therapeutics  
  Ellison D.H, Seminars in Nephrology, 1/1/1999
• Defective processing and expression of the thiazide-sensitive NaCl cotransporter as a cause of Gitelman’s Syndrome  
  Kunchaparty S, Palcso M, Berkman J, Velazquez H, Desir GV, Bernstein P, Reilly RF, Ellison DH, Am. J. Physiol, 1/1/1999
• The distal convoluted tubule of the rabbit coexpresses NaCl cotransporter and 11-hydroxysteroid dehydrogenase 2  
  Velazquez H, Naray-Fejes-Tøth A, Silva T, Andujar E, Reilly RF, Desir G, Ellison DH, Kidney International, 1/1/1998
• 11beta-hydroxysteroid dehydrogenase, mineralocorticoid receptor and thiazide-sensitive Na-Cl cotransporter expression by distal tubules  
  Bostanjoglo M, Reeves WB, Reilly FF, Velázquez H, Robertson N, Litwack G, Morsing P, Dœrup J, Bachmann S, Ellison DH, J.Am. Soc.Nephrol, 1/1/1998
• AJKD Journal Club, ‘Hyperkalemia and trimethoprim-sulfamethoxazole’  
  Ellison DH, Am. J. Kidney Dis, 1/1/1997
• Expression of the Na-K-2Cl cotransporter by macula densa and thick ascending limb of rat and rabbit nephron  
  Obermuller N, Kunchaparty S, Ellison D.H, Bachmann S, J. Clin. Invest, 1/1/1996
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Books/Book Chapters

• Endocrine Emergencies: Recognition and Treatment 
  Chapter: Diabetes Insipidus 
  Page 127 - 138Ellison, D.HEditors: D.L. Loriaux.Springer Science+Business Media, New York, NY2014
• Endocrine Emergencies: Recognition and Treatment 
  Chapter: SIADH 
  Page 115 - 126Ellison, D.H. HyponatremiaEditors: D.L. Loriaux.Springer Science+Business Media, New York, NY2014
• Schrier’s Diseases of the Kidney 
  Chapter: Mechanisms of Diuretic Action 
  Ellison, D.H., Hoorn, E.J., Schrier, R.WEditors: TM Coffman, FJ Falk, BM Molitoris, EG Neilson, and RW Schrier.Wolters Kluwer, Philadelphia, PA2013
• Core Concepts in the Disorders of Fluid, Electrolytes, and Acid-Base Balance 
  Chapter: Diuretic Therapy 
  Subramanya, AR and Ellison, DHEditors: DB Mount, MH Sayegh, AK Singh.Springer, New York, NY2013
• Nephrology Secrets 
  Chapter: Genetic Disorders of Sodium Transport 
  Maddirala S, Ellison DHEditors: Lerma, EV and Nissenson AR.Elsevier2012
• Nephrology Secrets 
  Chapter: Management of the patient with congestive heart failure 
  Rueda J, Ellison DHEditors: Lerma, EV and Nissenson AR.Elsevier2012
• Brenner & Rector’s The Kidney 
  Chapter: Diuretics 
  Ellison DH,Hoorn EJ, Wilcox CSEditors: Maarten W. Taal, Glenn M. Chertow, Philip A. Marsden, Karl Skorecki, Alan S.L. Yu, Barry M. Brenner.Elesvier, Philadelphia, PAEdition 9th,2012
• Seldin and Giebisch’sThe Kidney 
  Chapter: Physiology and Pathophysiology of Diuretic Action 
  Ellison, D.H2012
• Current Diagnosis & Treatment: Nephrology & Hypertension 
  Chapter: Disorders of Extracellular Volume: Hypovolemia and Hypervolemia 
  Ellison D.HEditors: Edgar V. Lerma, Jeffry S. Berns, Allen R. Nissenson.McGraw Hill Medical, New York, NY2009
• Therapy in Nephrology and Hypertension 
  Chapter: Diuretic Use in Edema and the Problem of Resistance 
  Ellison DH, Wilcox CEditors: Wilcox CS.W.B. Saunders CompanyEdition 3rd,2008
• Molecular and Genetic Basis of Renal Disease 
  Chapter: Hereditary disorders of collecting duct sodium and potassium transport 
  Ellison DH, Thomas CPEditors: Mount, DB and Pollak, MR.Saunders, Philadelphia, PA2008
• Seldin and Giebisch’s The Kidney 
  Chapter: Physiology and Pathophysiology of Diuretic Action 
  Okusa, M.D., Ellison, DHEditors: Alpern, R, Hebert, S.C.2008
• Brenner and Rector’s The Kidney 
  Chapter: Diuretics 
  Ellison DH,Wilcox C.SEdition 8th,2008
• Heart Failure 
  Chapter: Diuretics in congestive heart failure 
  Ross A, Hershberger RE, Ellison DHEditors: AM Feldman.Blackwell2006
• Primer on Kidney Diseases 
  Chapter: Edema and the Clinical Use of Diuretics 
  Ellison DHEditors: Greenberg A, Cheung AK, Coffman TM, Falk RJ, Jennette JC.National Kidney Foundation, Elsevier Saunders2005
• Therapy in Nephrology and Hypertension 
  Chapter: Diuretics: Use in Edema and the Problem of Resistance 
  Ellison DH, Wilcox CEditors: Brady HR & Wilcox CS.W.B. Saunders CompanyEdition 2nd,2003
• Acid-Base and Electrolyte Disorders 
  Chapter: Salt Wasting Disorders 
  Ellison DHEditors: DuBose TD, Hamm LL.W.B. Saunders Company2002
• Diseases of the Kidney and Urinary Tract 
  Chapter: Mechanisms of Diuretic Action 
  Ellison DH, Okusa MD. Schrier, R.WLippincott Williams & Wilkins, Philadelphia, PAEdition 7th,2001
• Manual of Nephrology 
  Chapter: The Edematous Patient: Cardiac Failure, Cirrhosis, and Nephrotic Syndrome 
  Page 1 - 20Ellison DH, Schrier RWEditors: R.W. Schrier.Little, Brown and Company1999
• Atlas of Diseases of the Kidney 
  Chapter: Disorders of Sodium Balance 
  Ellison DHEditors: R.W. Schrier.Current Medicine, Philadelphia, PA1999
• The Kidney: Physiology and Pathophysiology 
  Chapter: Physiology and pathophysiology of diuretic action 
  Okusa MD,Ellison DHEditors: Seldin, D.W. Giebisch.G.Academic Press, San Diego, CAEdition 3rd,1999
• Therapy in Nephrology and Hypertension 
  Chapter: Diuretic Resistance 
  Ellison DH.& Wilcox, CEditors: Brady H. R. & Wilcox, C.S..W.B. Saunders Company1998
• Principles of Medical Biology 
  Chapter: The physiologic basis of diuretic drug action and synergism 
  Page 577 - 599Ellison DHEditors: E.E. Bittar& N. Bittar.JAI Press, Inc, Greenwich, CT1997
• Clinical Physiology and Use of Diuretic Agents 
  Chapter: Adaptation to Diuretic Drugs 
  Page 209 - 231Ellison DHEditors: D. Seldin, G. Giebisch.Academic Press1997
• Clinical Physiology and Use of Diuretic Agents 
  Chapter: Circulatory Support: Dopamine and Dopamine Agonists as Adjuncts to Diuretic Therapy 
  Page 301 - 319Ellison DHEditors: D. Seldin, G. Giebisch.Academic Press1997
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Lectures

• Aldosterone action on the kidney 
  New York, NY - 1/1/2015
• Diuretic Resistance 
  Washington, DC - 1/1/2015
• From Genes to Bedside 
  Nigmegen, Nethterlands - 1/1/2014
• Potassium and Blood Pressure 
  Berlin, Germany - 1/1/2014
• Renal Medicine 
  Aspen, CO - 1/1/2014
• WNK and NCC 
  Dallas, TX - 1/1/2013
• Sodium and Potassium in Health and Disease 
  Geneva, Switzerland - 1/1/2012
• Rational Approach to Diuretic Resistance and A Novel Signaling Pathway in the Distal Nephron Regulates Salt Balance and Blood Pressure 
  1/1/2012
• WNK Kinases, Tacrolimus, and Blood Pressure 
  San Francisco, CA - 1/1/2012
• Gordon Syndrome 
  Boston, MA - 1/1/2012
• Aldosterone and the Distal Tubule 
  Houston, TX - 1/1/2012
• Aldosterone and the DCT 
  Cairns, Australia - 1/1/2012
• Salt Sensitive Hypertension: Basic Perspective’ 
  Los Angeles, CA - 1/1/2012
• SPAK and WNK: positive and negative regulators of salt transport 
  Berlin, Germany - 1/1/2011
• Regulation of NaCl Cotransport 
  1/1/2011
• WNK Kinases and the Distal Nephron 
  1/1/2011
• A Practical Approach to Diuretic Resistance 
  1/1/2010
• Mechanisms of sodium chloride co-transport regulation by a WNK signalling complex’ 
  Manila, Phillippines, 2010; Zurich, Switzerland, 2009 - 1/1/2010
• WNKs regulate NaCl cotransport 
  Saxons River, VT - 1/1/2010
• WNK kinases 2010: An update 
  1/1/2010
• Mechanisms of Diuretic Resistance 
  1/1/2010
• WNK signaling complex 
  1/1/2009
• Treatment of Diuretic Resistance’ 
  1/1/2009
• How potassium lowers blood pressure: lessons from a rare disease 
  1/1/2009
• Getting water from a stone: lessons in diuretic resistance’ 
  1/1/2008
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Other

• Syndrome of Inappropriate Antidiuretic Hormone Sections 
  Ellison DH, American College of Physicians, PIER