DavidEdwardComingsMD

PubMed

• Beyond the lack of association between IFNG +874T>A polymorphism and personality traits in healthy Japanese subjects: Possible ethnic-specific effects
  Valerio Napolioni, David E. Comings
  Brain, Behavior, and Immunity. 2016-01-01
• 13 citations
  Interaction between infectious diseases and personality traits: ACP1*C as a potential mediator.
  Valerio Napolioni, Damian R. Murray, David E. Comings, Warren R. Peters, Radhika Gade-Andavolu
  Infection, Genetics and Evolution. 2014-08-01
• 5 citations
  Modulation of a number of genes on personality traits in a sample of healthy subjects.
  Raffaella Calati, Maria Salvina Signorelli, Florence Gressier, O. Bianchini, Stefano Porcelli
  Neuroscience Letters. 2014-04-30

Journal Articles

• GSK-3 Beta genetic variability in patients with Multiple Sclerosis.  
  Daniela Galimberti, James MacMurray, Diego Scalabrinia, Chiara Fenoglio, Milena De Riz, Cristoforo Comi, David Comings, Francesca Cortini, Chiara Villa, Maria Serpen..., Neurosci Lett., 6/1/2011
• Generational Association Studies of Dopaminergic Genes in Reward Deficiency Syndrome (RDS) Subjects: Selecting Appropriate Phenotypes for Reward Dependence Behaviors.  
  Kenneth Blum1, Amanda LC Chen, Marlene Oscar-Berman, Thomas JH Chen, Joel Lubar5, Nancy White, Judith Lubar, Abdalla Bowirrat8, Eric Braverman, John Schoolfield, Roger..., Int J Environ Res Public Health. (Epub 2011 Nov 29), 1/1/2011
• Sexually dimorphic effect of the Val66Met polymorphism of BDNF on susceptibility to Alzheimer's disease: New data and meta-analysis.  
  Fukumoto N, Fujii T, Combarros O, Kamboh MI, Tsai SJ, Matsushita S, Nacmias B, Comings DE, Arboleda H, Ingelsson M, Hyman BT, Akatsu H, Grupe A, Nishimura AL, Zatz M, ..., Am J Med Genet B Neuropsychiatr Genet., 1/1/2010
• Genes and Happiness.  
  Blum, K, Thomas JH Chen, TJH, Chen, ALH, B. William Downs, W, Roger L. Waite, RL, Reinking, J, Mallory Kerner, M, Braverman, D, DiNubile, N, Rhoades, P, Eric R. Braver..., Gene Ther Mol Biol, 1/1/2009
• The association between the estrogen receptor TA polymorphism and harm avoidance.  
  Andevlu-Gade, R,, MacMurray, J., Comings, D.E., Calati, R., Chiesa, A. Serreti, A., Neuroscience Letters, 1/1/2009
• Attention-Deficit-Hyperactivity Disorder and Reward Deficiency Syndrome.  
  Blum, K. A. Chen, L-H, Braverman, E.R., Comings, D.E., Chen, T.J.H., Arcuri, V., Blum, S.H., Meshkin, B.,,Downs, B.W., Waite, R.L., Notaro, A., Lubar, J., Williams, L..., Neuropsychiatric Disease and Treatment, 1/1/2008
• Activation Instead of Blocking Mesolimbic Dopaminergic Reward Circuitry Is A Preferred Modality In The Long Term Treatment of Reward Deficiency Syndrome (RDS) – A Comm...  
  Blum, K, Lih, A, Chen, C, Tung, H, Braverman, E, Chen, TJH, Blum, SH, Cassel, K, Downs, BW, Waite, RL, Williams, L, Prihoda, TJ, Kerner, M, Palomo,T, Comings, DE, Osc..., Theoretical Biology & Medical Modeling, 1/1/2008
• The impact of biomics technology and DNA directed anti-obesity targeting of the brain reward circuitry.  
  Chen, ALC, Blum, K, Chen, TJH, Rhinking, J, Waite, RL, Downs, BW, Braverman, ER, Arcuri, V, Kerner, M, Notaro, A, Cassek, K, Blum,SH, Bagchi, D, Bagchi, M, Robarge, A,..., Gene Ther Mol Biol, 1/1/2008
• Chromium Picolinate (CrP) a putative anti-obesity nutrient induces changes in body composition as a function of the Taq1 dopamine D2 receptor polymorphisms in a random...  
  Thomas JH Chen, Kenneth Blum, Gilbert Kats, Eric R. Braverman, Arthur Eisenberg, Mark Sherman, Katharine Davis, David E. Comings, Robert Wood, Dennis Pullin, Vanessa A..., Gene Ther Mol. Biol., 1/1/2007
• Maternal age at the birth of the first child as an epistatic factor in polygenic disorders.  
  Comings, D.E. MacMurray, J.M., Am.J. Med. Genetics B Neuropsychiatric Genetics., 1/1/2006
• Attention Deficit Hyperactivity Disorder: A common genetic disorder affecting how our brain functions.  
  Comings, D.E., Chen, T.J., Blum, K. Blum, S.H., Theoretical Biology & Medical Modelling, 12/23/2005
• Neurogenetic interactions and aberrant behavioral co-morbidity of attention deficit hyperactivity disorder (ADHD): dispelling myths.  
  Comings, D.E. Thomas JH Chen, Kenneth Blum, Julie F Mengucci, Seth H Blum, Brian Meshkin., Theoretical Biology and Medical Modeling, 12/23/2005
• Risk of late-onset Alzheimer's disease associated with BDNF C270T polymorphism.  
  Olin D, MacMurray J, Comings DE, Neurosci Lett, 6/1/2005
• Are dopaminergic genes involved in a predisposition to pathological aggression? Hypothesizing the importance of "super normal controls" in psychiatricgenetic research ...  
  Chen TJ, Blum K, Mathews D, Fisher L, Schnautz N, Braverman ER, Schoolfield J, Downs BW, Comings DE., Med. Hypothesis, 1/1/2005
• A functional variant of lymphoid tyrosine phosphatase is associated with type I diabetes.  
  Bottini,N., Musumeci,L., Alonso,A., Rahmouni,S., Nika,K., Rostamkhani,M., MacMurray,J., Pellecchia,M., Eisenbarth,G.S., Comings,D.E., Mustelin,T., Nature Genetics, 1/1/2004
• Association of CCR5 delta32 deletion with early death in multiple sclerosis.  
  Gade-Andavolu,R., Comings,D.E., MacMurray,J., Cheng, L. S-C.. Tourtellotte,W.W.. Rosthamkhani,M., Cone,L.A., Genetics in Medicine, 1/1/2004
• RANTES: A Genetic risk marker for multiple sclerosis  
  Gade-Andavolu, R.G., Comings, D.E., MacMurray,J., Vuthoori, R.K., Touretellott, W.W., Nagra, R.M., Cone, L.A., Multiple Sclerosis, 1/1/2004
• Variants of the Orexin2/hcrt2 receptor gene indentifies in patients with excessive daytime sleepiness and patients with Tourette’s syndrome comorbidity.  
  Thompson, M.D., Comings, D., Abughazalah, R, Jeresch,Y., Wade, J., Sakurai,T., Tokita, S., Yoshida, T., Tanaka, H., Yanagisawa, M., Burnham,W.M., Moldfsky, H., Amer. J. Med. Genetics Part B Neuropsychiatric genetics, 1/1/2004
• Role of the cholinergic muscarinic 2 receptor (CHGRM2) gene in cognition.  
  Comings,D.E., Wu,S., Rostamkhani,M., McGue,M.,Burt,A., MacMurray,J.P., Molecular Psychiatry, 1/1/2003
• The Androgen Gene as an epistatic factor.  
  MacMurray, J.P., Comings, D.E., Am J Med Genet (Neuropsychiatric Genetics), 1/1/2003
• Maternal age at the birth of the first child as an epistatic factor in psychiatric genetics.  
  Comings, D. E. and MacMurray, J. P., AM J Med Genet (Neuropsychiatric Genetics), 1/1/2003
• Association between the vesicular monamine transporter VMAT and co-morbid symptoms in Tourette’s syndrome patients.  
  Comings,D.E., Rostamkhani, M., Emami,R.. MacMurray, J.P., Am.J. Med. Genetics (Neurospychiatric Genetics), 1/1/2003
• The Real Problem with Association Studies  
  Comings, D.E., Am. J. Med. Genet. (Neuropsychaitric Genetics), 1/1/2003
• A Multi-gene Test for the Risk of Sporadic Breast Cancer.  
  Comings, D.E., Gade-Andavolu, R., Cone,L.A, Muhleman, D. MacMurray, J.P., Cancer, 1/1/2003
• A "Line Item" approach to the identification of genes involved in polygenic behavioral disorders: The adrenergic a2A (ADRA2A) gene.  
  Comings,D.E., Gonzalez,N.S., Cheng,Li S-C., MacMurray,J., Am.J.Medical Genetics (Neurospychiatric Genetics), 1/1/2003
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Books/Book Chapters

• Anti-Aging Therapetics. Volume VIII. American Academy of Anti-Aging Medicine. 
  Chapter: Reward Deficiency Syndrome (RDS): Neurogenetic aspects of aging and related behavioral disorders specific to dopaminergic pathways. 
  Page 9 - 26Blum, Ken, Ph.D. Thomas JK Chen, Ph.D. Seth H. Blum, B.A., David E Comings, M.D, Julie F. Foster R.N. Brian Meshkin, B.Sc, Bernard W. Downs B.BA, Eric R. Braverman, M.D.Editors: Klatz, R. and Goldman, R..A4M Publications, Chicago, IL2006
• Nature Encyclopedia of the Genome. 
  Chapter: Polygenic Inheritance. 
  Comings, D.E.Nature MacMillian, London2003
• Encyclopedia of Life Sciences. 
  Chapter: Behavior Genetics – Human 
  Comings, D.E.Nature MacMillian, London2003
• Coon's Current Therapy 2003. 
  Chapter: Treatment of Tourette Syndrome. 
  Page 983 - 987Comings, D.EEditors: Rakel and Bope.Elsiver Science (USA), New York2003
• The Biodemography of Human Reproduction and Fertility 
  Chapter: Evidence of an emerging collision between the fertility transition and genotyhpe dependent fertility differentials. 
  MacMurray,J, Madrid,A., Bottini,E, Muhleman,D.,Comings,D.Editors: Rodgers,J.L. Kohler,H.P..Kluwer Academic Publishers, Boston2002
• Molecular Genetics and Human Personality. 
  Chapter: The role of the DRD2 and other dopamine genes in personality traits. 
  Page 165 - 191Comings, D. E., G. Saucier, and J. P. MacMurray.Editors: Benjamin, J., R. P. Ebstein, and R. H. Belmaker.American Psychiatric Press.2002
• The Biodemography of Fertility. 
  Chapter: The impact of father-absence on age at menarche and sexual symptoms in children and aldosescents admitted for educational and behavioral problems. 
  Huss,M.,MacMurray,J., Johnson,P., Lehmkuhl,U., Comings,D.E.Editors: Peter,H-P. and Rogers,J.L..Kluwer Academic Publishers2000
• Attention Deficit Disorders and Comorbidities in Children, Adolescents and Adults. 
  Chapter: ADHD with Tourette Syndrome or Tic Disorders. 
  Comings, D. E.Editors: Brown, T. E..Am.Psychiat.Press, Washington2000
• Genetic Influences on Fertility and Sexuality 
  Chapter: Age of first childbirth: A major selective factor for psychiatric genes in the twentieth century. 
  Page 271 - 288Comings, D. E.Editors: J. Rogers, and D. Rowe.2000
• Genetic Influence on Fertility and Sexuality. 
  Chapter: Association between the endothelialion nitric oxide synthase gene (NOS3) reproductive behaviors, and twinning 
  Page 303 - 316MacMurray, Kovacs,B., McGue, M., Johnson,J.P., Blake, H., Comings, D.E.Kluwer Academic Publishers2000
• Genetics of Fertility 
  Chapter: A study of factors involved in mediation of age at childbearing and offspring sex-ratio 
  MacMurray, J. and Comings, D.E.Editors: Rogers, J. and D. Rowe.2000
• Science, Treatment and Prevention of Antisocial Behavior: Application to the Criminal Justice System. 
  Chapter: Molecular genetics of ADHD and conduct disorder: Relevance to the treatment of recidivistic antisocial behavior. 
  Page 1 - 25Comings, D. E.Editors: Fishbein, D..Civic Research Institute, Inc., New York, N.Y2000
• Encyclopedia of Violence in the United States. 
  Chapter: Molecular genetics of violence. 
  Page 24 - 25Comings, D. E.Editors: R. Rottesman.Charles Schribner's Sons, New York1999
• Some genetic aspects of human sexual behavior in Males, Females, and Behavior: Toward Biological Understanding. 
  Page 1 - 12Comings, D. E.Editors: L. Ellis.Praeger, New York1998
• Advances in Population: Psychosocial Perspectives Vol 3 
  Chapter: Genetic influences on childbearing motivation: A theoretical framework and some emperical evidence. 
  Miller, W. B., D. J. Pasta, MacMurray, J., C. Chiu, S. Wu, and Comings, D.E.Editors: Edited by LJ Severy, WB Miller.Jessica Kingsley, London1998
• Genetic Indluences on Fertility –Related Processes. 
  Chapter: Genetic influences on childbearing motivation: Further testing a theoretical framework. 
  Miller, W., D. Pasta, MacMurray, J., and Comings, D.E.,.Editors: Edited by NIH and Society for the Study of Social Biology,.Tucson, AZ1997
• Genetic Influences on fertility-related processes. 
  Chapter: X-linked genes, twinning, and fertility related behavior. 
  MacMurray, J., Miller, W. and Comings, D.E.Editors: Edited by NIH and Society for the Study of Social Biology,.Tucson, AZ1997
• Genetic Influences on Rertility-Related Processes. 
  Chapter: Years of education and age of first childbirth: Evidence that genes associated with learning and related disorders are the major factor in the timing of childbirth, and that these genes are increasing 
  Comings, D. E.Editors: NIH and Society for the Study of Social Biology.Tucson, AZ1997
• Search for the Tourette Syndrome and Human Behavior Genes. 
  Comings, D. EHope Press1996
• Handbook of Psychiatric Genetics. 
  Chapter: Polygenetic inheritance of psychiatric disorders. 
  Page 235 - 260Comings, D. E.Editors: Blum, K., E. P. Noble, R. S. Sparks, and P. J. Sheridan.CRC Press, Boca Raton, FL1996
• Individual Differences in the Biobehavioral Etiology of Drug Abuse. 
  Chapter: Genetic factors in drug abuse and dependence. 
  Page 16 - 38Comings, D. E.Editors: Gordon, H. W. and M. D. Glantz.National Institut on Drug Abuse, Washington, D.C.1996
• The Gene Bomb. Does higher education and advanced technology accelerate the selection of genes for learning disorders, ADHD, addictive, and disruptive behaviors? 
  Comings, D. E.Hope Press, Duarte, CA1996
• Behavioral Neurology of Movement Disorders 
  Chapter: Tourette Syndrome: A Behavioral Spectrum Disorder. 
  Page 293 - 303Comings, D. E.Editors: Weiner, W. J. and Lang, A.E..Raven Press, NY1995
• Handbook of Tourette's Syndrome and Related Tic and Behavioral Disorders 
  Chapter: Comorbid Behavioral Disorders 
  Page 111 - 147Comings, D. E. and Comings, B. G.Editors: Kurlan, R.Marcel-Decker, Inc., New York1993
• Tourette Syndrome and Human Behavior. 
  Comings, D. E.Hope Press, Duarte, CA1990
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Abstracts/Posters

• Genetics of Pathological Gambling and Substance Use Disorders. (Abstract)
  Comings, D.E., European Neuropsychopharmacology; Meeting of the European Congress of Neuropsychopharmacology, Paris, 1/1/2006
• Molecular genetic and electrophysiological basis of "Reward Deficiency Syndrome": Risk of substance use disorder in attention-deficit-hyperactivity disorder probands. ...
  Blum, K., Braverman, E. R., Lubar, J. F., Lubar, J. O., Cull, J. G., Eisenberg, A., Sherman, M., Comings, D. E., Wise, J. A., and Monastra, V., ASAM Meeting, New York, 4/1/1999
• The genetics of pathological gambling: The additive effect of multiple genes.
  Comings, D. E., Gade-Andavolu, R., Gonzalez, N., S. Wu, Muhleman, D., Dietz, G., Blake, H., MacMurray, J.P., L. J. Rugle, H. R. Lesieur, and R. J. Rosenthal., National Council on Problem Gambling Meeting, Las Vegas, NV, 6/1/1998
• Association of endopeptidase (CD10NE) dinucleotide repeat polymorphism with anxiety, depression, and P300 amplitude.
  Johnson, J. P., Dietz, G., Gade-Andavolu, R., Blake, H., Muhleman, D., G. Saucier, MacMurray, J., and Comings, D.E., Am.J.Med.Gen.(Neuropsych.Genet.); International Congress of Psychiatric Genetics, Bonn, Germany, 1/1/1998
• Androgen receptor gene, conduct disorder and oppositional defiant disorder.
  Comings, D. E., S. Wu, and Muhleman, D., Am.J.Med.Gen.(Neuropsych.Genet.) ; International Congress Psychiatric Genetics, Bonn, Germany, 1/1/1998
• Phenotypic expression of neuronal nicotinic acetylcholine receptor gene (CHRNA4) in stressed and unstressed subjects.
  Comings, D. E., Wu, S., Johnson, J. P., and MacMurray, J., Am.J.Med.Gen.(Neuropsych.Genet.) ; International Congress Psychiatric Genetics, Bonn, Germany, 1/1/1998
• Multiple additive associations: A technique for the identification of genes in polygenic disorders.
  Comings, D. E., Gade-Andavolu, R., Gonzalez, N., S. Wu, Muhleman, D., Blake, H., Dietz, G., G. Saucier, and MacMurray, J., Am.J.Med.Gen.(Neuropsych.Genet.) ; International Congress Psychiatric Genetics, Bonn, Germany, 1/1/1998
• Norepinephrine genes, ADHD and Learning disorders.
  Comings, D. E., Gade-Andavolu, R., Gonzalez, N., S. Wu, Blake, H., and MacMurray, J., Am.J.Med.Gen.(Neuropsych.Genet.) ; International Congress Psychiatric Genetics, Bonn, Germany, 1/1/1998
• The molecular genetics of Attention Deficit Hyperactivity Disorder and Tourette Syndrome: Common, hereditary, treatable, behavioral disorders that are common in a pris...
  Comings, D. E., Academy of Criminal Justice Meeting, 1/1/1998
• Association of OB gene with obesity, depression and anxiety in young women. (Abstract)
  Comings, D. E., Gade, R., MacMurray, J., Muhleman, D., Johnson, J., Verde, R. and Peters, W., Psychiat.Genet; American Society of Human Genetics Meeting, San Francisco, CA, 1/1/1996
• Dopamine transporter gene (DAT1) in Tourette syndrome and autism.
  Ring, R. H. and Comings, D.E., 1995 World Congress Psychiatric Genetics, 1/1/1995
• Polygenic inheritance at a Molecular Level: The additive effect of Three Dopaminergic Genes in Tourette Syndrome, ADHD, and Conduct Disorder. (Abstract)
  Comings, D.E., Wu, S., Chiu, H., Ring, R.H., Ahn, C., Muhleman, D., Dietz, G., and Gade, R., American Society of Human Genetics meeting, Minneapolis, MN, 1/1/1995
• The haplotype relative risk technique lacks power in polygenic inheritance.
  Comings, D. E., 1995 World Congress Psychiatric Genetics, 1/1/1995
• IQ and drug abuse.
  Comings, D. E., 1995 World Congress Psychiatric Genetics, 1/1/1995
• Polygenic inheritance of psychiatric disorders: A hypothesis.
  Comings, D. E., 1995 World Congress Psychiatric Genetics, 1/1/1995
• Sequence and polymorphism studies of the human tryptophan 2,3-dixoygenase (TDO2) gene.
  Comings, D. E., Muhleman, D., Dietz, G., Gade, R., C. Chiu, S. Wu, and MacMurray, J., 1995 World Congress Psychiatric Genetics, 1/1/1995
• Polygenic inheritance of Tourette syndrome (TS) and ADHD: The additive effect of three dopaminergic genes.
  Comings, D. E., H. Wu, C. Chiu, R. S. Ring, C. Ahn, Muhleman, D., Dietz, G., and Gade, R., 1995 World Congress Psychiatric Genetics, 1/1/1995
• Dopamine D2 receptor gene in Tourette syndrome (TS).
  Comings, D. E., Muhleman, D., C. Chiu, Dietz, G., and Gade, R., 1995 World Congress Psychiatric Genetics, 1/1/1995
• Comings, D. E., Chiu, C., Muhleman, D., and MacMurray., J., 1995 World Congress Psychiatric Genetics, 1/1/1995
• The role of DRD2 genetic variants in impulsive behaviors in samples of normal individuals and substance abusers. (Abstract)
  MacMurray, J., Flanagan, S., and Comings, D. E., 9th World Congress of Psychiatry, 1/1/1993
• Role of variants of the dopamine D2 receptor (DRD2) gene as genetic risk factors in smoking. (Abstract)
  Comings, D.E., Ferry, l. Brandshaw-Robinson, S., Burchette, R., Dino, M., Chiu, C., Muhleman, D., Tobacco-Related Disease Research Program First TRDRP Scientific Conference, 1/1/1993
• Tourette syndrome: A neuropsychiatric spectrum disorder. (Abstract)
  Comings, D. E. and Comings, B. G., Am.J.Hum.Genet., 1/1/1993
• D2 receptor gene haplotypes and decreased fecundability in female Hispanics. (Abstract)
  Legro, R. S., Dietz, G., D. Comings, Lobo, R.A., Kovacs, B., Soc.Gynecologic Invest., Toronto, 1/1/1993
• D3 receptor polymorphisms associated with oligo-ovulation among female Hispanics. (Abstract)
  Legro, R. S., Muhleman, D., D. Comings, R. A. Lobo, and B. Kovacs., Soc.Gynecologic Invest., Toronto, 1/1/1993
• D2 receptor gene haplotypes in female Hispanics are significantly associated with gonadotropins and fecundity but not ovulation. (Abstract)
  Legro, R. S., G. W. Dietz, Comings, D.E., and B. W. Kovacs., The Endocrine Society, 1/1/1993
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Other

• Modern Molecular Genetics. 
  Comings, D.E.
  10/24/1967
• Genes, Chromosomes and Human Disease. 
  Comings, D.E., Beutler, E., and Teplitz, R.
  10/1/1966