DavidCachiaMD

PubMed

• 30 citations
  Alliance A071401: Phase II Trial of Focal Adhesion Kinase Inhibition in Meningiomas With SomaticMutations.
  Priscilla K Brastianos, Erin L Twohy, Elizabeth R Gerstner, Timothy J Kaufmann, A John Iafrate
  Journal of Clinical Oncology. 2023-01-20
• Current Use and Limitations of Cultured High-Grade Meningioma Cells in Neuro-Oncological Research - In Response to: "Caution Using Meningioma Cell Lines as Tumor Models".
  Jaime L Martinez Santos, Paola Suarez-Meade, David Cachia, Scott Lindhorst, Arabinda Das
  Cancer Investigation. 2021-10-19
• 9 citations
  MGMT-inhibitor in combination with TGF-βRI inhibitor or CDK 4/6 inhibitor increases temozolomide sensitivity in temozolomide-resistant glioblastoma cells
  Arabinda Das, Fraser Henderson, Mohammed Alshareef, Guilherme B. F. Porto, Indira Kanginakudru
  Clinical & Translational Oncology. 2021-03-01

Journal Articles

• Inability of positive phase II clinical trials of investigational treatments to subsequently predict positive phase III clinical trials in glioblastoma  
  Mandel JJ, Yust-Katz S, Patel A, Cachia D, Liu D, Park M, Yuan Y, Kent K, de Groot JF, Neuro Oncol, 1/10/2018
• Radiographic patterns of progression with associated outcomes after bevacizumab therapy in glioblastoma patients  
  Cachia D, Elshafeey NA, Kamiya-Matsuoka C, Hatami M, Alfaro-Munoz KD, Mandel JJ, Colen R, DeGroot JF, J Neurooncol, 1/1/2017
• Dorsal Column Myelopathy after Intrathecal Chemotherapy for Leukemia  
  Pinnix CC, Chi L, Jabbour EJ, Milgrom SA, Smith GL, Daver N, Garg N, Cykowski MD, Fuller G, Cachia D, Kamiya C, Woodman K, Dinardo C, Jain N, Kadia TM, Pemmaraju N, Oh..., Am J Hematol, 1/1/2017
• Interventions for the management of fatigue in adults with a primary brain tumour  
  Day J, Yust-Katz S, Cachia D, Wefel J, Katz LH, Tremont I, Bulbeck H, Armstrong T, Rooney AG, Cochrane Database Syst Rev, 1/13/2016
• Impact of IDH-1 mutation status on outcome in clinical trials for recurrent glioblastoma  
  Mandel JJ, Cachia D, Liu D, Wilson C, Aldape K, Fuller G, de Groot JF, J Neurooncol, 1/1/2016
• Severe peripheral neuropathy following carfilzomib, rituximab, and dexamethasone for initial treatment of Waldenstrom's macroglobulinemia  
  Alfaraj WA, Cachia D, Tummala S, Thomas SK, Manasanch EE, Ann Hematol, 1/1/2016
• Rip1 and Rip3 complex regulates radiation-induced programmed necrosis in glioblastoma  
  Das A , McDonald D, Dixon-Mah YN, Jacqmin DJ, Vandergrift III WA, Lindhorst SM, Cachia D, Varma AK, Vanek K, Banik NL, Jenrette III JM, Raizer JJ, Giglio P, Patel SJ, Tumour Biol, 1/18/2015
• Middle cerebral artery territory infarct due to Cryptococcus infection: An uncommon indication for CSF analysis in stroke patients  
  Cachia D, Singh C, Tetzlaff M, Penas Prado M, Diagn Cytopathol, 1/4/2015
• Cough and confusion in an elderly gentleman with chronic lymphocytic leukemia  
  Cachia D, Makhija M, Smith T, J Clin Neurosci, 1/1/2015
• Synergistic effects of crizotinib and temozolomide in experimental FIG-ROS1 fusion-positive glioblastoma  
  Das A, Cheng RR, Hilbert MLT, Dixon-Moh YN, Decandio M, Vandergrift WA, Banik NL, Lindhorst SM, Cachia D, Varma AK, Patel SJ, Giglio P, Cancer Growth Metastasis, 1/1/2015
• Primary and Secondary Gliosarcomas: clinical, molecular and survival characteristics  
  Cachia D, Kamiya-Matsuoka C, Mandel JJ, Olar A, Cykowski MD, Armstrong TS, Fuller GN, Gilbert MR, De Groot JF, J Neurooncol, 1/1/2015
• Ischemic stroke in patients with gliomas at The University of Texas-MD Anderson Cancer Center  
  Cachia D, Kamiya-Matsuoka C, Yust-Katz S, Rodriguez YA, Garciarena P, Rodarte EM, Tremont-Lukats IW, J Neurooncol, 1/1/2015
• Myelopathy following intrathecal chemotherapy in adults: a single institution experience  
  Cachia D, Kamiya-Matsuoka C, Pinnix CC, Chi L, Kantarjan HM, Cortes JE, Daver N, Woodman K, J Neurooncol, 1/1/2015
• C11orf95-RELA fusion present in a primary supratentorial ependymoma and recurrent sarcoma  
  Cachia D, Wani K, Penas-Prado M, Olar A, McCutcheon IE, Benjamin RS, Armstrong TS, Gilbert MR, Aldape KD, Brain Tumor Pathol, 1/1/2015
• Leptomeningeal dissemination in glioblastoma; An inspection of risk factors, treatment, and outcomes at a single institution  
  Mandel JJ, Yust-Katz S, Cachia D, Wu J, Liu D, de Groot JF, Yung AWK, Gilbert MR, J Neurooncol, 1/1/2014
• Primary Brain Tumors and Posterior Reversible Encephalopathy Syndrome  
  Cachia D, Kamiya-Matsuoka C, Olar A, Armstrong TS, Gilbert MR, Neuro Oncol Pract, 1/1/2014
• Synchronous rosette forming glioneuronal tumor and diffuse astrocytoma with molecular characterization: a case report  
  Cachia D, Penas Prado M, Theeler B, Hamilton J, McCutcheon I, Fuller GN, Clin Neuropathol, 1/1/2014
• L5 radiculopathy causing absent superficial peroneal sensory response  
  Cachia D, Salameh J, Neurological Bulletin, 1/1/2013
• Cognitive delay in a 7-year-old girl  
  Cachia D, Stine C, Neurology, 1/1/2013
• A rare presentation of hypertrophic olivary degeneration secondary to primary CNS lymphoma  
  Cachia D, Izzy S, Smith T, Ionete C, JAMA Neurol, 1/1/2013
• Widely metastatic meningioma  
  Cachia D, Alderson L, Smith T, Yunus S, Arch Neurol, 1/1/2012
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Books/Book Chapters

• 5 Minute Clinical Consult 
  Chapter: Cluster Headache 
  Cachia D, Mitchell A, Fontneau N2012
• Merritt's Neurology 
  Chapter: Spinal Tumors 
  Cachia D, Tatsui C, Gilbert MREdition 13th,
• Ependymomas: Prognostic Factors, Treatment Strategies and Clinical Outcomes 
  Chapter: Prognosis and outcomes in ependymal tumors. 
  Metrus NR, Cachia D
• NeuroICU Comprehensive Board Review 
  Chapter: Neuro-oncology section. 
  Santos Pinheiro F, Cachia DEdition 1st,
• Top 10 Contributions on Neurology 
  Chapter: Molecular Markers in Gliomas and their Impact in Clinical Practice 
  Henderson Jr. F, Cachia D, Varma A
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Abstracts/Posters

• Overcoming Radiation Resistance in Meningioma: The Emerging Role of CDK4/6 Inhibitor.
  Cachia D, Society of Neuro-Oncology Meeting, New Orleans, LA, 1/1/2018
• C18-Ceramide Analogue Drug Overcomes Resistance to Temozolomide in Gliobastoma.
  Cachia D, Society of Neuro-Oncology Meeting, New Orleans, LA, 1/1/2018
• Galectin-1 upregulates CXCR4 in glioblastoma through upregulation of CXCR4 via NF-KappaB activation.
  Cachia D, American Association for Cancer Research, 1/1/2018
• Multi Cranial Neuropathy Secondary To Primary Glioblastoma Of Trigeminal Nerve: Case Report.
  Cachia D, American Academy of Neurology, Los Angeles, CA, 1/1/2018
• Radiation induced late malignant meningioma transformation: CDK 4/6 Inhibitor therapy.
  Cachia D, Society of Neuro-Oncology Meeting, San Francisco, CA, 1/1/2017
• Unlocking the Promise of Myxoma Virus Therapy- Combination of Radiation plus Crizotinib or Bevacizumab to Enhance Efficacy in Glioblastoma.
  Cachia D, Society of Neuro-Oncology Meeting, San Francisco, CA, 1/1/2017
• Investigating the expression of antigen processing molecules in Brain Metastases of Triple-negative breast cancers.
  Cachia D, Society of Neuro-Oncology Meeting, San Francisco, CA, 1/1/2017
• Targeting CCR2 Signaling in Pediatric Medulloblastoma.
  Cachia D, Society of Neuro-Oncology Meeting, San Francisco, CA, 1/1/2017
• Galectins in Glioblastoma: Opportunities for combined Therapy.
  Cachia D, American Association for Cancer Research, 1/1/2017
• American Academy of Neurology?
  Cachia D, American Academy of Neurology, 1/1/2016
• Ependymomas arising outside of the central nervous system: a case series.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• Improving gemcitibine-mediated radio-sensitization using molecularly targeted meningioma therapy.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• Combination therapy of LDK378 and INC280 (INCB028060) enhances temozolomide sensitivity in MGMT unmethylated glioblastoma: pre clinical assessment.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• Preclinical testing of dietary histone deacetylase inhibitors on fresh FIG-ROS1 positive human glioblastoma tissue in ex-vivo models.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• Diffusion kurtosis imaging of the subventricular zone in glioblastoma.
  Cachia D, Society of Neuro-Oncology Meeting, Scottsdale, AZ, 1/1/2016
• Dovitinib (TKI258), a Multi-target Angiokinase inhibitor, is Effective Regardless of NF Mutation Status in Meningioma.
  Cachia D, Society for Neuro-Oncology Conference on Meningioma, 1/1/2016
• Impact of IDH-1 Mutation Status on Outcome in Clinical Trials for Recurrent Glioblastoma.
  Cachia D, American Academy of Neurology, 1/1/2016
• Relationship between coping style and psychological distress among individuals diagnosed with primary brain tumors.
  Cachia D, American Psychooncology Society, 1/1/2016
• Radiographic patterns of progression with associated outcomes after bevacizumab therapy in glioblastoma patients.
  Cachia D, Society of Neuro-Oncology Meeting, San Antonio, 1/1/2015
• IDH1 mutation status and outcome in clinical trials for recurrent glioblastoma.
  Cachia D, American Society of Oncology Annual Meeting, 1/1/2015
• Primary Brain Tumors and Posterior Reversible Encephalopathy Syndrome
  Cachia D, Society of Neuro-Oncology Meeting, Miami, FL, 1/1/2014
• Temozolomide-based therapy for the management of progressive pituitary carcinoma.
  Cachia D, Society of Neuro-Oncology Meeting, Miami, FL, 1/1/2014
• Myelopathy following intrathecal chemotherapy: a case series in adults.
  Cachia D, Society of Neuro-Oncology Meeting, Miami, FL, 1/1/2014
• GNAQ gene mutation in an intermediate-grade melanocytic tumor of the thoracic spinal cord.
  Cachia D, Society of Neuro-Oncology Meeting, San Francisco, CA, 1/1/2013
• Peripheral Neuropathy Following Hair Dye Exposure: A Case Report.
  Cachia D, American Academy of Neurology (AAN), San Diego, CA, 1/1/2013
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Lectures

• Treatment of Diffuse Gliomas in Adults: What's New? 
  1/1/2018
• Anti-Tumor Activity of CDK 4/6 Inhibitor Palbociclib in Rb+ Meningioma: Pre-clinical Assessment. 
  1/1/2016
• RIP3 is a Critical Regulator of Radiation Induced Programmed Necrosis and Inflammation in a Preclinical Model of Glioblastoma. 
  1/1/2016
• Interventions for fatigue in people with gliomas. 
  Scottsdale, AZ - 1/1/2016
• Molecular classification of diffuse gliomas; Ready for prime time? 
  University of Massachusetts - 1/1/2014
• Another Neuropathy... 
  University of Massachusetts - 1/1/2013
• Meningioma: A benign brain tumor? 
  University of Massachusetts - 1/1/2012
• Case Presentation: Brachial Amyotrophic Diplegia 
  University of Massachusetts - 1/1/2011
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