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Office
1 Hoag Dr
Newport Beach, CA 92663Phone+1 949-764-5610
Summary
- David R. Braxton M.D. is board certified in Anatomic and Clinical Pathology. His clinical interests and expertise include the histological diagnosis of gastrointestinal, liver, and pancreatic disease as well as the application of molecular diagnostics in personalized medicine.
David has ongoing research investigations in the pathogenesis of Barrett’s esophagus, the biology of pancreatic cancer, and in regenerative medicine and stem cell biology. His research experience includes basic laboratory work at the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research of the University of Southern California. During this time, David explored the molecular development of the primitive endoderm by using small molecule kinase inhibitors to selectively guide the differentiation of human embryonic stem cells towards primitive foregut and hepatic fates. Furthermore, he participated in the characterization of a novel marker of biliary progenitors through the isolation and culture of primary human liver cells. David’s longstanding interest in molecular and cellular biology began as an undergraduate majoring in Biochemistry at the Florida State University, where his thesis focused on regulation of the cell division cycle.
Education & Training
- UCLA David Geffen School of Medicine/UCLA Medical CenterFellowship, Molecular Genetic Pathology, 2015 - 2016
- University of Pennsylvania Health SystemFellowship, Gastrointestinal Pathology, 2014 - 2015
- Emory University School of MedicineResidency, Pathology-Anatomic and Clinical, 2010 - 2014
- Keck School of Medicine of the University of Southern CaliforniaClass of 2010
- Florida State UniversityBS, Biochemistry, with Honor, Cum Laude, 2001 - 2005
- UCLA David Geffen School of Medicine/UCLA Medical CenterResidency, Pathology-Anatomic and Clinical
Certifications & Licensure
- CA State Medical License 2015 - 2025
- PA State Medical License 2014 - 2015
- American Board of Pathology Pathology - Anatomic/Pathology - Clinical
- American Board of Pathology Pathology - Molecular Genetic
Awards, Honors, & Recognition
- The Ray and Fern Wilson Scholarship for Cancer Research Financial Aid Office, Keck School of Medicine, University of Southern California, 2009
- Heath Science Weekly Article Recognition Keck School of Medicine, University of Southern California, 2008
- The Dean's Research Scholarship Keck School of Medicine, University of Southern California, 2008
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Publications & Presentations
PubMed
- 18 citationsMolecular and cytogenomic profiling of hepatic adenocarcinoma expressing inhibinA, a mimicker of neuroendocrine tumors: proposal to reclassify as "cholangioblastic var...David R. Braxton, Debra Saxe, Nevena Damjanov, Kristen Stashek, Stuti Shroff
Human Pathology. 2017-04-01 - 4 citationsAn Expert, Multidisciplinary Perspective on Best Practices in Biomarker Testing in Intrahepatic Cholangiocarcinoma.David C Madoff, Nadine Abi-Jaoudeh, David Braxton, Lipika Goyal, Dhanpat Jain
The Oncologist. 2022-10-01 - 2 citationsNot in the Same Vein: Inflammatory Bowel Disease, Malignancy, and Enterocolic Lymphocytic Phlebitis.Orly N Farber, Alexa R Weingarden, Christopher Lee, David R. Braxton, David B. Bingham
Digestive Diseases and Sciences. 2021-02-01
Journal Articles
- Necrotizing Sialometaplasia-like Change of the Esophageal Submucosal Glands Is Associated with Barrett's EsophagusBraxton DR, Nickleach DC, Lui Y, Farris AB, Virchows Archiv, 1/27/2014
- Utility of GATA3 Immunohistochemistry for Diagnosis of Metastatic Breast Carcinoma in Cytology SpecimensBraxton, D.R., Cohen, C. and Siddiqui, M.T., Diagn. Cytopathol, 1/1/2014
Books/Book Chapters
Abstracts/Posters
- Gastrointestinal Tract Adenocarcinomas Display Intratumoral Heterogeneity Detectable By 47 Gene Next Generation Sequencing PanelBraxton DR, Morrissette JD, Furth EE, United States & Canadian Academy of Pathology Annual Meeting, 1/1/2015
- A Case of Mesenteric Inflammatory Veno-occlusive Disease Mimicking New Onset Inflammatory Bowel Disease in a Healthy 71-year-old ManBraxton, DR, 2014 Advances in Inflammatory Bowel Diseases: Crohn's & Colitis Foundation's Clinical and Research Conference, Orlando, Florida, 1/4/2014
- Barrett Esophagus Dysplasia Characterization through Digital Image AnalysisMartin DR, Braxton DR, Farris AB., USCAP 103rd Annual Meeting, San Diego, California, 1/1/2014
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Lectures
- The GCTM-5 Monoclonal Antibody is a Biomarker for Progenitors in the Columnar Lined EsophagusUnited States And Canadian Academy of Pathologists, Washington DC - 1/1/2010
- Expression and Subcellular Localization of the Transcription Factor YY1 in Mammalian CellsBiomedical Science Department, College of Medicine, Florida State University - 1/14/2005
Other
- The Conundrum of the Columnar Lined Esophagus - Understanding the Pathogenesis of Barrett's Esophagus Through Novel Stem Cell Technologies, ThesisBraxton DR
1/1/2008 - Expression and Subcellular Localization of the Yin-Yang-1 Transcription Factor in Mammalian Cells. Digital Scholarship Repository, Bachelors of Science ThesisBraxton DR
1/1/2005
Press Mentions
- Deep Lens First to Integrate Cancer Genetic Data into AI Platform to Rapidly Match Patients to Precision Therapies and Clinical TrialsMay 19th, 2020
- Hoag To Use AI Profiling To Expedite Cancer Care for PatientsAugust 22nd, 2023
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