DavidRBickersMD

PubMed

• 2 citations
  Hypersensitivity to non-β-lactam antibiotics.
  Hans F Merk, David R Bickers
  Allergologie Select. 2022-01-01
• Author Correction: Patched1 haploinsufficiency severely impacts intermediary metabolism in the skin of Ptch1+/-/ODC transgenic mice.
  Changzhao Li, Bharat Mishra, Mahendra Kashyap, Zhiping Weng, Shaida A. Andrabi
  Scientific Reports. 2021-10-11
• 2 citations
  Genomic profiling of late-onset basal cell carcinomas from two brothers with nevoid basal cell carcinoma syndrome.
  O. Hasan Ali, Andrey A. Yurchenko, O. Pavlova, Ambra Sartori, David Bomze
  Journal of the European Academy of Dermatology and Venereology. 2021-02-01

Journal Articles

• Downregulation of STRA6 expression in epidermal keratinocytes leads to hyperproliferation-associated differentiation in both in vitro and in vivo skin models  
  Skazik C, Amann PM, Heise R, Marquardt Y, Czaja K, Kim A, Ruhl R, Kurschat P, Merk HF, Bickers DR, Baron JM, J Invest Dermatol, 1/1/2014
• Tazarotene: randomized, double-blind, vehicle-controlled, and open-label concurrent trials for basal cell carcinoma pr evention and therapy in patients with basal cell...  
  Tang JY, Chiou AS, Mackay-Wiggan JM, Aszterbaum M, Chanana AM, Lee W, Lindgren JA, Raphael MA, Thompson BJ, Bickers DR, Epstein EH Jr, Cancer Prev Res, 1/1/2014
• Hair follicle disruption facilitates pathogenesis of UVB-induced cutaneous inflammation and basal cell carcinoma development in Ptch(+/-)mice  
  Xu J, Weng Z, Arumugam A, Tang X, Chaudhary SC, Li C, Christiano AM, Elmets CA, Bickers DR, Athar M, Am J Pathol, 1/1/2014
• Strange bedfellows  
  Burgdorf WH, Bickers DR, Hoenig LJ, JAMA Dermatol, 1/1/2014
• Dermatologic Relationships Between the United States and German-Speaking Countries Part I-Before 1933  
  Burgdorf WH, Bickers DR, JAMA Dermatol, 1/1/2013
• Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption  
  Srivastava RK, Li C, Chaudhary SC, Ballestas ME, Elmets CA, Robbins DJ, Matalon S, Deshane JS, Afaq F, Bickers DR, Athar M, Toxicol App Pharmacol, 1/1/2013
• Dermatologic relationships between the United States and German-speaking countries: part 2—the exodus of Jewish dermatologists  
  Burgdorf WH, Bickers DR, JAMA Dermatol, 1/1/2013
• Dermatologic relationships between the United States and German-speaking countries: part 3—the Europeans come to the United States  
  Burgdorf WH, Bickers DR, JAMA Dermatol, 1/1/2013
• Bechet vs Behcet: the name is not the same  
  Burgdorf WH, Bickers DR, Hoenig LJ, JAMA Dermatol, 1/1/2013
• A toxicological and dermatological assessment of alkyl cyclic ketones when used as fragrance ingredients  
  Belsito D, Bickers D, Bruze M, Calow P, Dagli ML, Fryer AD, Greim H, Miyachi Y, Saurat JH, Sipes IG, Food Chem Toxicol, 1/1/2013
• Unfolded protein response (UPR) signaling regulates arsenic trioxide-mediated macrophage innate immune function disruption  
  Srivastava RK, Li C, Chaudhary SC, Ballestas ME, Elmets CA, Robbins DJ, Matalon S, Deshane JS, Afaq F, Bickers DR, Athar M, Toxicol Appl Pharmacol, 1/1/2013
• Dermatologic relationships between the United States and German-speaking countries: part 2-the exodus of Jewish dermatologists  
  Burgdorf WH, Bickers DR, JAMA Dermatol, 1/1/2013
• Dermatologic relationships between the United States and German-speaking countries: part 3-the Europeans come to the United States  
  Burgdorf WH, Bickers DR, JAMA Dermatol, 1/1/2013
• A Review of the Journal of Investigative Dermatology's Most Cited Publications over the Past 25 Years and the Use of Developing Bibliometric Methodologies to Assess Jo...  
  Bickers DR, Modlin RL, J Invest Dermatol, 1/1/2012
• A toxicological and dermatological assessment of aryl alkyl alcohol simple ester derivatives when used as fragrance ingredients  
  Belsito D, Bickers D, Bruze M, Calow P, Dagli ML, Fryer AD, Greim H, Miyachi Y, Saurat JH, Sipes, IG, Food Chem Toxicol, 1/1/2012
• A toxicological and dermatological assessment of cyclopentanones and cyclpentenones when used as fragrance ingredients  
  Belsito D, Bickers D, Bruze M, Calow P, Dagli ML, Dekant W, Fryer AD, Greim H, Miyachi Y, Saurat JH Sipes IG, Food Chem Toxicol, 1/1/2012
• Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome  
  Tang JY, Mackay-Wiggan JM, Aszterbaum M, Yauch RL, Lindgren J, Chang K, Coppola C, Chanana M, Marji J, Bickers DR, Epstein EH Jr, N Engl J Med, 1/1/2012
• Inhibiting the hedgehog pathway in patients with the basal-cell nevus syndrome  
  Tang JY, Mackay-Wiggan JM, Aszterbaum M, Yauch RL, Lindgren J, Chang K, Coppola C, Chanana M, Marji J, Bickers DR, Epstein EH Jr, N Engl J Med, 1/1/2012
• Induced Tumor Progression  
  Kim KH, Back JH, Zhu Y, Arbesman J, Athar M, Kopelovich L, Kim AL, Bickers DR, J Invest Dermatol, 1/1/2011
• Glycoprotein (ABCB1) expression in human skin is mainly restricted to dermal components  
  Skazik C, Wenzel J, Marquardt Y, Kim A, Merk HF, Bickers DR, Baron JM, Exp Dermatol, 1/1/2011
• A toxicological and dermatological assessment of macrocyclic ketones when used as fragrance ingredients  
  Belsito D, Bickers D, Bruze M, Calow P, Dagli ML, Fryer AD, Greim H, Miyachi Y, Saurat JH, Sipes IG, Food Chem Toxicol, 1/1/2011
• A toxicological and dermatological assessment of macrocyclic lactone and lactide derivatives when used as fragrance ingredients  
  Belsito D, Bickers D, Bruze M, Calow P, Dagli ML, Fryer AD, Greim H, Miyachi Y, Saurat JH, Sipes IG, Food Chem Toxicol, 1/1/2011
• A toxicologic and dermatologic assessment of cinnamyl phenylpropyl materials when used as fragrance ingredients  
  Belsito D, Bickers, D, Bruze M, Calow P, Dagli M, Fryer AD, Greim H, Miyachi Y, Saurat JH, Sipes IG, Food Chem Toxicol, 1/1/2011
• A toxicological and dermatological assessment of aryl alkyl alcohols when used as fragrance ingredients  
  Belsito D, Bickers D, Bruze M, Calow P, Dagli ML, Fryer AD, Greim H, Miyachi Y, Saurat JH, Sipes IG, Food Chem Toxicol, 1/1/2011
• Resveratrol Targets Transforming Growth Factor-Beta2 Signaling to Block UV-Induced Tumor Progression  
  Kim KH, Back JH, Zhu Y, Arbesman J, Athar M, Kopelovich L, Kim AL, Bickers DR, J Invest Dermatol, 1/1/2011
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Books/Book Chapters

• Therapy of Skin Diseases: A Worldwide Perspective on Therapeutic Approaches and Their Molecular Basis. 
  Chapter: General Pharmacology. 
  Page 21 - 27Bickers DREditors: Krieg T, Bickers DR, Miyachi Y.Springer-Verlag, Berlin, Germany2010
• Therapy of Skin Diseases: A Worldwide Perspective on Therapeutic Approaches and Their Molecular Basis. 
  Krieg T, Bickers DR, Miyachi YSpringer-Verlag, Berlin, Germany2010
• Therapy of Skin Diseases: A Worldwide Perspective on Therapeutic Approaches and Their Molecular Basis 
  Chapter: General Pharmacology. 
  Page 21 - 27Bickers DREditors: Krieg T, Bickers DR, Miyachi Y.Springer-Verlag, Berlin2010
• Therapy of Skin Diseases: A Worldwide Perspective on Therapeutic Approaches and Their Molecular Basis 
  Krieg T, Bickers DR, Miyachi YSpringer-Verlag, Berlin2010
• Functional Food: Herbs, Botanic and Teas. 
  Chapter: Licorice in Foods and Herbal Drugs: Chemistry, Pharmacology, Toxicology and Uses. 
  Wang ZY, Athar M, Bickers DREditors: Massa G, Oomah BD.Technomic Publishing Co., Lancaster, PA2000
• Functional Food: Herbs, Botanic and Teas 
  Chapter: Licorice in Foods and Herbal Drugs: Chemistry, Pharmacology, Toxicology and Uses. 
  Wang ZY, Athar M, Bickers DREditors: Massa G, Oomah BD.Technomic Publishing Co., Inc., Lancaster, PA, USA2000
• Fitzpatrick's Dermatology in General Medicine. 
  Chapter: The Porphyrias. 
  Page 1766 - 1803Bickers DR, Pathak Ma, Lim HWEditors: Freedberg IM, Eisen AZ, Wolff K, et al.McGraw-Hill, New York, NYEdition 5th,1999
• Fitzpatrick's Dermatology in General Medicine 
  Chapter: The Porphyrias. 
  Page 1766 - 1803Bickers DR, Pathak Ma, Lim HWEditors: Freedberg IM, Eisen AZ, Wolff K, et al.McGraw-Hill, New YorkEdition 5th,1999
• Conn's Current Therapy. 
  Chapter: Sunburn. 
  Page 865 - 868Bickers DR, Mercurio MGW.B. Saunders, Philadelphia, PA1997
• Conn's Current Therapy 
  Chapter: Sunburn. 
  Page 865 - 868Bickers DR, Mercurio MGW.B. Saunders, Philadelphia1997
• Photoimmunology: An Update. 
  Chapter: Photoimmunology of Photodynamic Therapy. 
  Page 257 - 264Mukhtar H, Zaidi SIA, Bickers DR, Elmets CAEditors: Krutmann J and Elmets CA.Blackwell Publishers, Berlin, Germany1995
• Photoimmunology: An Update 
  Chapter: : Photoimmunology of Photodynamic Therapy. 
  Page 257 - 264Mukhtar H, Zaidi SIA, Bickers DR, Elmets CAEditors: Krutmann J and Elmets CA.Blackwell Publishers, Berlin, Germany1995
• Modern Pharmacology. 
  Chapter: Drugs Used in Dermatological Disorders. 
  Page 523 - 534Chren MM, Bickers DREditors: Craig CR, Stitzel RE.Little Brown, Boston, MA1994
• Modern Pharmacology 
  Chapter: Drugs Used in Dermatological Disorders. 
  Page 523 - 534Chren MM, Bickers DREditors: Craig CR, Stitzel RE.Little Brown, BostonEdition 4th,1994
• Pharmacology of the Skin. 
  Chapter: Pharmacology of Psoralen Photochemotherapy. 
  Page 217 - 225Bickers DR, Mukhtar HEditors: Mukhtar H.CRC Press, Inc., Boca Raton, FL1992
• Pharmacology of the Skin. 
  Chapter: Cutaneous Metabolism of Xenobiotics and Steroid Hormones. 
  Page 89 - 109Mukhtar H, Agarwal R, Bickers DREditors: Mukhtar H.CRC Press, Inc., Boca Raton, FL1992
• Pharmacology of the Skin. 
  Chapter: Role of Reactive Oxygen Species in Skin. 
  Page 269 - 279Athar M, Agarwal R, Bickers DR, Mukhtar HEditors: Mukhtar H.CRC Press, Inc., Boca Raton, FL1992
• Textbook of Geriatric Medicine. 
  Chapter: Skin Aging. 
  Page 828 - 831Athar M, Agarwal R, Bickers DR, Mukhtar HEditors: Brocklehurst JC, Tallis RC, Fillit HM.Churchill-Livingstone, New York, NY1992
• Skin Pharmacology and Toxicology: Recent Advances. 
  Chapter: Skin as a Portal of Entry for Systemic Effect: Xenobiotic Metabolism. 
  Page 85 - 97Bickers DR and Mukhtar HEditors: Galli CL, Hensby CN and Marinovich M.Plenum Press, New York, NY1992
• Dermatopharmakologie und Dermatotherapie. 
  Bickers DR, Merk HDeGruyter Verlag, Berlin, Germany1992
• Pharmacology of the Skin 
  Chapter: Pharmacology of Psoralen Photochemotherapy. 
  Page 217 - 225Bickers DR, Mukhtar HEditors: Mukhtar H.CRC Press, Inc., Boca Raton1992
• Pharmacology of the Skin 
  Chapter: Cutaneous Metabolism of Xenobiotics and Steroid Hormones. 
  Page 89 - 109Mukhtar H, Agarwal R, Bickers DREditors: Mukhtar H.CRC Press, Inc., Boca Raton1992
• Pharmacology of the Skin 
  Chapter: Role of Reactive Oxygen Species in Skin. 
  Page 269 - 279Athar M, Agarwal R, Bickers DR, Mukhtar HEditors: Mukhtar H.CRC Press, Inc., Boca Raton1992
• Textbook of Geriatric Medicine 
  Chapter: Skin Aging. 
  Page 828 - 831Dalziel KL, Bickers DREditors: Brocklehurst JC, Tallis RC, Fillit HM.Churchill Livingstone, New YorkEdition 4th,1992
• Skin Pharmacology and Toxicology: Recent Advances 
  Chapter: Skin as a Portal of Entry for Systemic Effect: Xenobiotic Metabolism. 
  Page 85 - 97Bickers DR and Mukhtar HEditors: Galli CL, Hensby CN and Marinovich M.Plenum Press, New York1992
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Abstracts/Posters

• Tang X, Kim AL, Kopelovich L, Bickers DR, Athar M, J Invest Dermatol, 1/1/2004
• Phorbol-12 myristate 13-acetate (TPA) inhibits the induction of basal cell carcinomas in ptch1+/- Mice.
  Hebert J, Khaimskiy Y, Athar M, Kopelovich L, Bickers D, Epstein E, J Invest Dermatol, 1/1/2004
• Resveratrol-induced modulation of MEK-ERK signaling and cell cycle regulation in human epidermoid carcinoma A431 cells.
  Kim AL, Zhu H, Zhu Y, Athar M Bickers DR, J Invest Dermatol, 1/1/2004
• p38 MAP kinase signaling mediates inflammatory responses in UVB-irradiated human skin.
  Zhu Y, Kim AL, Tang X, Stiller M, Coppola C, Barsanti F, Athar M, Bickers DR, J Invest Dermatol, 1/1/2004
• Chemical inhibition of nuclear factor kappa B (NfkappaB) prevents UVB-induced squamous cell carcinomas (SCCs) in SKH-1 mice.
  Tang X, Kim AL, Kopelovich L, Bickers DR, Athar M, J Invest Dermatol, 1/1/2004
• Phorbol-12 myristate 13-acetate (TPA) inhibits the induction of basal cell carcinomas in ptch1+/-Mice.
  Hebert J, Khaimskiy Y, Athar M, Kopelovich L, Bickers D, Epstein E, J Invest Dermatol, 1/1/2004
• Immunization with the tumor antigen hedgehog-interacting-protein reduces and anti-rejection drug administration increases BCC formation in Ptc +/- mice treated with io...
  Vogt A, Hebert JL, Kopelovich L, Bickers DR, Epstein EH Jr, J Invest Dermatol, 1/1/2003
• Alpha- difluoromethylornithine (DFMO), a suicidal inhibitor of ornithine decarboxylase (ODC) prevents basal cell carcinomas (BCCs) in Ptc +/- heterozygous knockout mice.
  Tang X, Russo J, Epstein EH Jr, Kopelovich L, Bickers DR, Athar M, J Invest Dermatol, 1/1/2003
• p53 stabilization by CP-31398 restores wild type p53-dependent function in ultraviolet B (UVB) irradiated murine skin and in A431 cells.
  Athar M, Tang X, Kopelovich L, Bickers DR, J Invest Dermatol, 1/1/2003
• Role of prostaglandin E2 receptors in the pathogenesis of ultraviolet B (UVB)-induced non-melanoma skin cancers.
  Lee JL, Bickers DR, and Athar M, J Invest Dermatol, 1/1/2003
• DNA damage and cell cycle alterations in ultraviolet B-induced murine and human basal cell carcinomas.
  Kim AL, Zhu Y, Kopelovich L, Bickers DR, Athar M, J Invest Dermatol, 1/1/2003
• Celecoxib prevention of BCCs in basal cell nevus syndrome patients.
  Yu J, Aszterbaum M, Stiller M, Kopelovich L, Bickers DR, Epstein EH Jr, J Invest Dermatol, 1/1/2003
• p38 mitogen-activated protein kinases (MAPK's) mediate ultraviolet B (UVB)-induced Cox-2 expression and inflammation in the skin of SKH-1 hairless mice.
  Kim AL, Zhu Y, Bickers DR, Athar M, J Invest Dermatol, 1/1/2003
• Altered gene expression in normal human epidermal keratinocytes by retinoic acid isomers and their 4-oxo-metabolites: 4-oxo 13cis RA is the most potent derivative.
  Heise R, Bickers DR, Zwadlo-Klarwasser G, Merk HF, Jugert FK, Baron JM, J Invest Dermatol, 1/1/2003
• Immunization with the tumor antigen hedgehog-interacting-protein reduces and anti-rejection drug administration increases BCC formation in Ptc +/-mice treated with ion...
  Vogt A, Hebert JL, Kopelovich L, Bickers DR, Epstein EH Jr, J Invest Dermatol, 1/1/2003
• Alpha-difluoromethylornithine (DFMO), a suicidal inhibitor of ornithine decarboxylase (ODC) prevents basal cell carcinomas (BCCs) in Ptc +/-heterozygous knockout mice.
  Tang X, Russo J, Epstein EH Jr, Kopelovich L, Bickers DR, Athar M, J Invest Dermatol, 1/1/2003
• Augmented basal cell carcinomas development in ptch+/- heterozygous knockout mice over-expressing ornithine decarboxylase.
  Athar M, Russo J, Aszterbaum M, Kim AL, Zhang H, Tang X, Kopelovich L, Epstein EH Jr., and Bickers DR, Proc Amer Assoc Cancer Res, 1/1/2002
• Comparative effects of COX-1 and COX-2 inhibitors on UVB photocarcinogenesis in SKH-1 mice.
  Tang X, Athar M, Aszterbaum M, Kopelovich L, Epstein EH Jr, Bickers DR, Proc Amer Assoc Cancer Res, 1/1/2002
• Transcriptional activation of nuclear factor kappa B (NFkB) in ultraviolet B (UVB)-induced basal cell carcinomas (BCCs) in ptc+/- mice.
  Zhang H, Athar M, Tang M, Aszterbaum M, Kopelovich L, Epstein EH Jr, and Bickers DR, Proc Amer Assoc Cancer Res, 1/1/2002
• Blockade of hedgehog signaling inhibits ultraviolet B (UVB)-induced basal cell carcinomas (BCCs) in ptch+/- knockout heterozygous mice.
  Kim AL, Athar M, Tang X, Aszterbaum M, Kopelovich M, Epstein EH Jr, Bickers DR, Proc Amer Assoc Cancer Res, 1/1/2002
• Alpha-difluoromethyl ornithine (DFMO), an irreversible inhibitor of ornithine decarboxylase, abrogates ultraviolet B (UVB)-induced skin carcinogenesis in SKH-1 hairles...
  Russo JE, Athar M, Tang X, Aszterbaum M, Kopelovich L, Epstein EH Jr, Bickers DR, Proc Amer Assoc Cancer Res, 1/1/2002
• Chemoprevetion of basal cell carcinomas in the ptc+/- mouse.
  Aszterbaum M, Hebert J, Lee K, Athar M, Kopelovich L, Bickers DR, Epstein EH Jr, Proc Amer Assoc Cancer Res, 1/1/2002
• Innovative model for accelerated induction of cutaneous basal cell carcinomas: ptc+/- heterozygous knockout mice over-expressing ornithine decarboxylase.
  Athar M, Russo J, Kim AL, Zhang H, Tang X, Aszterbaum, Kopelovich L, Epstein EH Jr, Bickers DR, J Invest Dermatol, 1/1/2002
• Novel approach to cancer chemoprevention: Inhibition of sonic hedgehog (shh) signaling by cyclopamine (CPN) abrogates ultraviolet B (UVB)-induced basal cell carcinomas...
  Tang, M. Athar M, Kim AL, Kopelovich L, Epstein EH Jr, Bickers DR, J Invest Dermatol, 1/1/2002
• Target tissue regulation of retinoic acid isomers and their 4-oxo derivatives in cultured normal human keratinocytes.
  Merk HF, Jugert FK, Baron J, Bickers DR, Athar M, Schiffer R, Wiegand U, J Invest Dermatol, 1/1/2002
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Other

• An approach to the patient with photosensitivity. 
  Bickers DR, Mediguide Derm
  1/1/1987
• Principles of dermatopharmacology. 
  Bickers DR, Upjohn Publication
  1/1/1983
• Skin: A major environmental interface. 
  Bickers DR, Guide Prof Pharm
  1/1/1978