DarylPPearlsteinMD

Thoracic Surgery • Newport Beach, CA

Cardiovascular Surgery

Director, Thoracic Surgery & Lung Cancer, Hoag Memorial Hospital, Newport Beach and Irvine California

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Office
1 Hoag Drive
Building 41, Suite 122
Newport Beach, CA 92663
Phone+1 949-764-6166
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Summary

Daryl Pearlstein, M.D., is Director of Thoracic Surgery & Lung Cancer at Hoag Memorial Hospital. He is a board-certified thoracic surgeon specializing in surgery of the chest, including the lungs, mediastinum, diaphragm, chest wall, and esophagus. His areas of interest include all aspects of thoracic oncology (lung cancer, sarcomas, mediastinal malignancies, chest wall tumors, and esophageal cancer), as well as benign diseases, including achalasia, hiatal hernias, myasthenia gravis and hyperhidrosis. He also specializes in complex airway pathology including tracheal stenosis and central airway obstruction and utilizes ION® robotic navigation bronchoscopy and endobronchial ultrasound for diagnostic & therapeutic interventions.
Dr. Pearlstein began performing robotic surgery in 2008 and has centered his career around improving the patient experience. Utilizing minimally invasive techniques, including robotics, he provides thoracic surgical patients the fastest recovery possible and enables the most comfortable recuperation.
At Hoag Dr. Pearlstein hosts a mentorship site for robotic thoracic surgery, teaching surgeons from around the United States who wish to incorporate this technology into their practices.

Website: Robotic Thoracic Surgery

An educational website about Robotic Thoracic Surgery for colleagues and patients

Education & Training

Cedars-Sinai Medical CenterFellowship, Thoracic Surgery, 2005 - 2006
University of Utah HealthFellowship, Thoracic Surgery, 2003 - 2005
University of Illinois College of Medicine at ChicagoResidency, Surgery, 1997 - 2003
Vanderbilt University School of MedicineClass of 1996
Northwestern UniversityB.A., English, 1988 - 1992

Certifications & Licensure

CA State Medical License 2015 - 2025
FL State Medical License 2019 - 2021
WI State Medical License 2006 - 2015
IL State Medical License 1997 - 2008
UT State Medical License 2003 - 2006
American Board of Surgery Surgery
American Board of Thoracic Surgery Thoracic and Cardiac Surgery

Awards, Honors, & Recognition

Hoag Physician of the Quarter (Jan-Mar) 2017
Fellow American College of Chest Physicians, 2014
Fellow American College of Surgeons, 2013
Special Recognition, Top ABSITE Score, Nation American Board of Surgery, 2003
Surgeon of Excellence in Robotic Surgery Surgical Review Corporation
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Publications & Presentations

PubMed

121 citations
Mitochondrial requirement for endothelial responses to cyclic strain: implications for mechanotransduction.
Mir H. Ali, Daryl P. Pearlstein, Carol Mathieu, Paul T. Schumacker
American Journal of Physiology. Lung Cellular and Molecular Physiology. 2004-09-01
123 citations
Role of Mitochondrial Oxidant Generation in Endothelial Cell Responses to Hypoxia
Daryl P. Pearlstein, Mir H. Ali, Paul T. Mungai, Karen L. Hynes, Bruce L. Gewertz
Arteriosclerosis, Thrombosis, and Vascular Biology. 2002-04-01
3 citations
Improved Survival Outcomes in Medically Fit Patients With Early-Stage Non-Small-Cell Lung Cancer Undergoing Stereotactic Body Radiotherapy.
Jason Liu, Caressa Hui, Colton Ladbury, Thomas Waddington, Loretta Erhunmwunsee
Clinical Lung Cancer. 2021-01-19

Journal Articles

Robotic Lobectomy Utilizing the Robotic Stapler
Pearlstein DP, Ann Thorac Surg, 1/1/2016
Mitochondrial requirement of endothelial responses to cyclic strain: Implications for mechanotransduction
Ali MH, Pearlstein DP, Mathieu CE, Schumacker PT, Am J Physiol Lung Cell Mol Physiol, 1/1/2004

Abstracts/Posters

Transhiatal Esophagectomy with Trans-cervical Endoscopic Esophageal Mobilization.
Murtaza G, Gasparri M, Pearlstein DP, Haasler G, Tisol W, American Association for Thoracic Surgery Annual Meeting, Minneapolis, MN, 1/4/2013
Safety and efficacy of CT-guided hookwire localization of pulmonary nodules prior to video assisted thoracosopic (VATS) resection.
Pearlstein DP, Eastern Cardiothoracic Surgical Society 50th Annual Meeting, Naples, FL, 1/4/2012
Robotic giant para-esophageal hernia repair.
Murtaza G, Wyler Von Ballmoos M, Tisol W, Pearlstein DP, Masroor S, Haasler G, Gasparri MG, International Society of Minimally Invasive Cardiothoracic Surgery Meeting, Washington, DC, 1/1/2011
Transcervical endoscopic esophageal mobilization and lymph node dissection using endoscopic vessel harvesting instrumentation during transhiatal esophagectomy.
Tisol W, Gasparri M, Haasler G, Pearlstein DP, International Society of Minimally Invasive Cardiothoracic Surgery Meeting, Washington, DC, 1/1/2011
Electomagnetic navigation bronchoscopy performed by thoracic surgeons: One center’s early success.
Pearlstein DP, Quinn CC, Burtis CC, Ahn KW, Katch AJ, Society of Thoracic Surgeons 47th Annual Meeting, San Diego, CA, 1/1/2011
Mitochondrial Reactive Oxygen Species Mediated Changes in Endothelial Permeability and IL-6 Production.
Pearlstein DP, Ali M, Schumacker PT, American Thoracic Society International Conference, Toronto, Ontario, Canada, 1/1/2000
Mitochondrial Reactive Oxygen Species: A Link Between Endothelial Hypoxia and IL-6 Production
Pearlstein DP, Schumacker PT, Association for Academic Surgery Annual Meeting, Tampa, FL, 1/1/2000
Routine Examination of All Hernia Orifices Identified Unexpected Hernias During Total Extraperitoneal Laparoscopic Herniorrhaphy
Pearlstein DP, Lasky P, Society of Laparoendoscopic Surgeons Annual Meeting, Orlando, FL, 1/1/2000
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Lectures

Using Fluorescent Dye to Facilitate Robotic Resection of Pulmonary Nodules.
Tucson, AZ - 1/1/2018
Minimally Invasive Strategies for Biopsying Small Suspicious Pulmonary Nodules
Washington, DC - 1/1/2012
New Frontiers in Robotic Assisted General Thoracic Surgery.
Lanzhou, China - 1/1/2012
Update in Minimally Invasive General Thoracic Surgery
Chicago, IL - 1/1/2012
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Other

Safety and efficacy of CT-guided hookwire localization of pulmonary nodules prior to video assisted thoracosopic (VATS) resection.
Pearlstein DP, Surgery Update – News form the Department of Surgery
Medical College of Wisconsin - 1/1/2013
Electromagnetic Navigation Bronchoscopy.
Pearlstein DP, Surgery Update – News form the Department of Surgery
Medical College of Wisconsin - 1/1/2011
Video-Assisted Thoracic Surgery
Pearlstein DP, WUWM, Milwaukee Public Radio
1/20/2009
I-ELCAP Lung Cancer Screening Project
Pearlstein DP, Milwaukee Fox 6 Now TV
1/8/2007
Minimally Invasive Surgery for Lung Cancer
Pearlstein DP, Milwaukee Fox 6 Now TV
1/10/2006
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