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Office
Duke Medical Ctr
# 3156
Durham, NC 27710Phone+1 919-684-5018Fax+1 919-684-6458
Education & Training
- Duke University HospitalResidency, Surgery, 1970 - 1970
- Duke University HospitalResidency, Neurological Surgery, 1966 - 1968
- Duke University HospitalInternship, Transitional Year, 1965 - 1966
- Duke University School of MedicineClass of 1965
Certifications & Licensure
- NC State Medical License 1966 - 2025
- GA State Medical License 1965 - 1975
Clinical Trials
- Monoclonal Antibody Therapy in Treating Patients With Brain Metastases Start of enrollment: 1989 Jul 01
- Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Primary or Metastatic Brain Cancers Start of enrollment: 1993 Feb 01
- Monoclonal Antibody Therapy in Treating Patients With Recurrent Gliomas Start of enrollment: 1991 Nov 01
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Publications & Presentations
PubMed
- 1 citationsDevelopment of a high-throughput screening platform to identify new therapeutic agents for Medulloblastoma Group 3.Inés Fallon, Henar Hernando, Olga Almacellas-Rabaiget, Berta Marti-Fuster, Cesare Spadoni
SLAS Discovery. 2024-03-01 - Repurposing Clemastine to Target Glioblastoma Cell Stemness.Michael A Sun, Rui Yang, Heng Liu, Wenzhe Wang, Xiao Song
Cancers. 2023-09-18 - 8 citationsPolio virotherapy targets the malignant glioma myeloid infiltrate with diffuse microglia activation engulfing the CNS.Yuanfan Yang, Michael C Brown, Gao Zhang, Kevin Stevenson, Malte Mohme
Neuro-Oncology. 2023-09-05
Journal Articles
- Recurrent Glioblastoma Treated with Recombinant PoliovirusDarell Bigner, MD, The New England Journal of Medicine
- The Genomic Landscape of TERT Promoter Wildtype-IDH Wildtype GlioblastomaDaniel B. Loriaux, Darel D. Bigner, Fausto J. Rodriguez, Hai Yan, Bil H. Diplas, Henry S. Friedman, Roger E. McLendon, Nature
Press Mentions
- New Brain Tumor Drug Hits Market 16 Years After Duke Neurosurgeon's Discovery: ' Excited'August 27th, 2024
- FDA Gives Patients Hope After Approving Brain Cancer Drug with Duke TiesAugust 27th, 2024
- FDA Approves Brain Cancer Drug with Duke Ties Giving Patients HopeAugust 26th, 2024
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Grant Support
- Neuro-OncologyNational Cancer Institute2010–2012
- SRC On Primary Tumors Of The CNSNational Institute Of Neurological Disorders And Stroke2009–2012
- Ind, Regulatory And BioinformaticsNational Institute Of Neurological Disorders And Stroke2009–2012
- Administrative CoreNational Institute Of Neurological Disorders And Stroke2009–2012
- Brain Tumors - Immunological And Biological StudiesNational Cancer Institute2001–2012
- NeurooncologyNational Cancer Institute2005–2009
- Spore In Brain CancerNational Cancer Institute2004–2009
- Core--Developmental Research ProgramNational Cancer Institute2004–2008
- Core--Career Development ProgramNational Cancer Institute2004–2008
- SRC On Primary And Metastatic Tumors Of The CNSNational Institute Of Neurological Disorders And Stroke1994–2008
- Administration Support Core 5National Cancer Institute2004
- Spore In Brain CancerNational Cancer Institute2002–2003
- Rapid Development Of Glioma Targeting Reagents For TherapyNational Cancer Institute2002
- Comprehensive Cancer Center Core Support GrantNational Cancer Institute2002
- Clinical Trials With Solid Intracranial Tumors &Neoplastic MeningitisNational Institute Of Neurological Disorders And Stroke1999–2002
- Core--Immunoincompetent Rodent &Biohazard FacilityNational Cancer Institute1999–2002
- Core--General Laboratory And Animal SupportNational Institute Of Neurological Disorders And Stroke1994–2002
- Brain Tumors--Immunological And Biological StudiesNational Cancer Institute1992–2000
- Core--Cancer Center Isolation FacilityNational Cancer Institute1996–1998
- Research Training In Neuro-OncologyNational Institute Of Neurological Disorders And Stroke1992–1996
- Intrathecal Therapy Of Melanoma Neoplastic MeningitisNational Cancer Institute1991–1993
- SRC On Malignant Human Gliomas And MedulloblastomasNational Institute Of Neurological Disorders And Stroke1989–1993
- Increased Delivery Of Monoclonal Antibody RadioimmunoatherapyNational Institute Of Neurological Disorders And Stroke1989–1993
- Brain Tumors: Immunological And Biological StudiesNational Cancer Institute1988–1991
- Malignant Human Gliomas And MedulloblastomaNational Institute Of Neurological Disorders And Stroke1985–1988
- Brain Tumors: Immunological And Biological StudiesNational Cancer Institute1985–1987
- Conference On Brain Tumor Research And TherapyNational Institute Of Neurological Disorders And Stroke1985
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