DanielBenedictSchmolzeMD

Pathology • Duarte, CA

Anatomic Pathology, Clinical Pathology

Associate Professor of Pathology

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Office
1500 Duarte Rd
Duarte, CA 91010
Phone+1 626-256-4673

Fax+1 626-218-5310

Education & Training

Beth Israel Deaconess Medical CenterFellowship, Breast Pathology, 2015 - 2016
University of Massachusetts Medical SchoolClass of 2011
SUNY BuffaloNo Degree, Basic Science, 2002 - 2004
Rochester Institute of TechnologyB.S., Information Technology, 2000 - 2002
Simon's Rock College of BardA.A., Liberal Arts, 1996 - 1998

Certifications & Licensure

CA State Medical License 2016 - 2025
MA State Medical License 2011 - 2016
American Board of Pathology Pathology - Anatomic/Pathology - Clinical

Publications & Presentations

PubMed

Poor response of HER2-positive mucinous carcinomas of breast to neoadjuvant HER2-targeted therapy: A study of four cases.
Min Han, Daniel Schmolze, Javier A Arias-Stella 3rd, Christina H Wei, Joanne Mortimer
Annals of Diagnostic Pathology. 2025-02-01
Organ-Specific Immune Setpoints Underlie Divergent Immune Profiles across Metastatic Sites in Breast Cancer.
Colt A Egelston, Weihua Guo, Diana L Simons, Jian Ye, Christian Avalos
Cancer Immunology Research. 2024-11-04
Tumor draining lymph nodes connected to cold triple-negative breast cancers are characterized by Th2-associated microenvironment.
Weihua Guo, Jiayi Tan, Lei Wang, Colt A Egelston, Diana L Simons
Nature Communications. 2024-10-04

Journal Articles

Distribution of Cholesterol and HER2 in Patient Breast Cancer Cells using Quantitative Single Molecule Localization Microscopy
Brehove, M.S., Tobin, S.J., Wakefield, D.L., Jones, V., Liu, X., Schmolze, D.B., Jovanovic-Talisman, T, Biophysical Journal, 1/1/2019
Single molecule localization microscopy coupled with touch preparation for the quantification of trastuzumab-bound HER2
Tobin, S.J., Wakefield, D.L., Jones, V., Liu, X., Schmolze, D.B., Jovanovic-Talisman, T., Scientific Reports, 1/1/2018
A System for Automated Adequacy Assessment of Thyroid Fine Needle Aspiration Samples
Schmolze, D.B., Fischer, A.H., Archives of Pathology and Laboratory Medicine, 1/1/2018
Identification of Tissue Specific DNA Methylation Signatures for Thyroid Nodule Diagnostics
Yim, J., Choi, A., Li, A., Qin, H., Chang, S., Tong, S-W., Chu, P., Kim, B-W., Schmolze, D.B., Lew, R., Ibrahim, Y., Poroyko, V., Salvatierra, S., Baker, A., Wang, J.,..., Clinical Cancer Research, 1/1/2018
Dual mTOR Kinases MLN0128 Inhibitor Sensitizes HR+/HER2+ Breast Cancer Patient-derived Xenografts to Trastuzumab or Fulvestrant
Hsu, P., Wu, V. S., Kanaya, N., Petrossian, K., Hsu, H., Ngyuyen, D., Schmolze, D.B., Kai, M., Liu, C., Lu, H., Chu, P., Vito. C.A, Kruper, L., Mortimer, J. Chen., S., Clinical Cancer Research, 1/1/2018
Complete regression of cutaneous metastases with systemic immune response in a patient with triple negative breast cancer receiving p53MVA vaccine with pembrolizumab
Yuan, Y., Kos, F.J, He, T., Yin, H.H., Li, M., Har, Hardwick, N., Zurcher, K., Schmolze, D.B., Lee, P., Pillai, R.K., Chung, V., Diamond, D.D., OncoImmunology, 1/1/2017
Crowdsourcing scoring of immunohistochemistry images: Evaluating Performance of the Crowd and an Automated Computational Method
Irshad, H., Oh, E.Y., Schmolze, D.B., Quintana L.M., Collins, L., Tamimi, R.M., Beck, A.H., Nature Scientific Reports, 1/1/2017
Direct comparison between confocal and multiphoton microscopy for rapid histopathological evaluation of unfixed human breast tissue
Yoshitake, T., Giacomelli, G.G., Cahill, L.C., Schmolze, D.B., Vardeh, H., Faulkner-Jones, B.E., Connolly, J.L., Fujimoto, J. G., Journal of Biomedical Optics, 1/1/2016
Using Point of Care Glucose Meters in Critically Ill: Assessing Meter Performance in the Clinical Context
Schmolze, D.B., Horowitz, G.L., Tolan, N.V., Point of Care: The Journal of Near-Patient Testing and Technology, 1/1/2016
A 63 Year-Old Man With Rapidly Progressive Dementia
Hale, A., Geerling, J., Schmolze, DB., Pfannl, R., Karchmer, AW, Clinical Infectious Diseases, 1/1/2016
Assessment of breast pathologies using nonlinear microscopy
Tao, Y. K., Shen, D., Sheikine, Y., Ahsen, O. O., Wang, H. H., Schmolze, D. B., Fujimoto, J. G., et al, Proceedings of the National Academy of Sciences, 1/1/2014
Value of Additional Level Sections in the Evaluation of Lymph Nodes for Endometrial Carcinoma Staging
Schmolze, D.B., Awtrey, C. S., & Hecht, J. L., American Journal of Clinical Pathology, 1/1/2013
Characterization and Analysis of the Composition and Dynamics of the Mammalian Riboproteome
Reschke, M., Clohessy, J. G., Seitzer, N., Goldstein, D. P., Breitkopf, S. B., Schmolze, D. B., Pandolfi, P. P., et al, Cell Reports, 1/1/2013
Advances in microscopy techniques
Schmolze, D. B., Standley, C., Fogarty, K. E., & Fischer, A. H., Archives of Pathology & Laboratory Medicine, 1/1/2011
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Abstracts/Posters

Relations between sleep and inflammation in African American and White young adults: Testing mediating and moderating mechanisms.
Doan, S.N., Fuller-Rowell, T., Schmolze, D.B., Seewaldt, V., AACR (American Association for Cancer Research) Science of Cancer Disparities Annual Meeting, 1/1/2018
Leiomyoadenomatoid Tumor: A Collision Tumor or a Variant of Adenomatoid Tumor?
Al-Sannaa, G., El-Zaateri, Z., Andino, L., Schmolze, D.B., Chapman, D., Ayala, A., Ro, J., CAP Annual Meeting, 1/1/2018
Segmentation-based Data Augmentation in Deep Networks for Magnification Invariant Breast Cancer Detection.
Jonnalagedda, P., Schmolze, D.B., Bhanu, B., UC Riverside Bioengineering Symposium, 1/1/2018
Latent Class Modeling of Childhood BMI Trajectories.
Schmolze, D.B, Doan, S.N., Evans, G., Life History Research Society Annual Meeting, 1/1/2018
Evaluation of The Tumor Microenvironment Using Multiplex Immunohistochemistry.
Himchack, E., Muirhead, D., Lewallen, M., Schmolze, D.B., Song, J., Kim, Y., Nathwani, B., Weisenburger, D., Herrera, A., Pillai, R., United States and Canadian Academy of Pathology Annual Meeting, 1/1/2018
Mutational and Immune Profiling of Metaplastic Breast Cancer: Correlation with Survival.
Afkhami, M., Schmolze, D.B., Yost, S., Frankel, P., Dagis, A., Louie, C., Pillai, R., Aoun, P., Yuan, Y, United States and Canadian Academy of Pathology Annual Meeting, 1/1/2018
Prognostic significance of PD-L1 expression in cancer, stromal, and immune cells in triple-negative breast cancer.
Behrendt, C.E., Schmolze, D.B., Lee, P.P., Apple, S., United States and Canadian Academy of Pathology Annual Meeting, 1/1/2018
Early Hallmarks for Tumor-induced Dysfunctional Sentinel Lymph nodes in Breast Cancer.
He, T-F., Tu, T.Y., Wang, R., Rosario, A., Solomon, S., Wortman, J.C., Yu, C.C., Apple, S.K, Schmolze, D.B., Yuan, Y., Lee, P.P., Molecular Medicine Tri-Con Annual Meeting, 1/1/2018
A novel super-resolution microscopy approach to determine the HER2 status of breast cancer tissue.
Tobin, S.J, Wakefield, D.L., Jones, V., Liu, X., Schmolze, D.B., Jovanovic-Talisman, T., City of Hope RSO Advance Meeting, 1/1/2018
A phase II clinical trial of the combination of pembrolizumab and selective androgen receptor modulator GTx-024 in patients with advanced androgen receptor positive tr...
Yuan, Y., Frankel, P., Synold, T., Lee, P., Yost, S., Martinez, N., Tang, A., Mendez, B., Schmolze, D.B., Apple, S., Hurria, A., Waisman, J., Somlo, G., Tank, N., Sedr..., San Antonio Breast Cancer Symposium Annual Meeting, 1/1/2017
Immune profiling of paired primary and recurrent triple negative breast cancer.
He, T-F., Yost, S., Schmolze, D.B., Wang, R., Rosario, A, Tu, T., Chu, P., Lee, P., Yuan, Y., San Antonio Breast Cancer Symposium Annual Meeting, 1/1/2017
A System for Automated Adequacy Assessment of Thyroid Fine Needle Aspiration Samples.
Schmolze, D.B., Fischer, A.H., United States and Canadian Academy of Pathology Annual Meeting, 1/1/2017
Using Point-of-Care Glucose Meters in the Critically Ill: Assessing Meter Performance in the Clinical Context.
Schmolze, D.B., Horowitz, G.L., Tolan, N.V., American Association of Clinical Chemistry Annual Meeting, 1/1/2015
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Lectures

AstraZeneca Interactive Tumor Board
1/21/2018
Quantitative Super Resolution Microscopy with Touch Prep for HER2 Assessment in Breast Cancer
1/20/2018

Other

MVPNets: Multi-Viewing Path Deep Learning Neural Networks for Magnification Invariant Diagnosis in Breast Cancer.
Jonnalagedda, P., Schmolze, D.B., Bhanu, B, IEEE BIBE 2018
1/1/2018
Clinical Pathology Improvement Program-Parvovirus Infection and Transient Aplastic Crisis.
Schmolze, D.B., cap.org
1/1/2014
EMDomics: Earth Mover's Distance for Differential Analysis of Genomics Data.
Schmolze, D.B., Beck, A.H., and Nabavi, S., R Package Version 0.99.0.
http://cran.rproject.org/web/packages/saps/
1/1/2014
ega: Error Grid Analysis.
Schmolze, D.B., R Package Version 1.0.0.
http://cran.rproject.org/web/packages/ega/
1/1/2014
saps: Significance Analysis of Prognostic Signatures.
Schmolze, D.B., Beck, A. H.., and Haibe-Kains, B., R Package Version 1.0.0.
http://cran.rproject.org/web/packages/saps/
1/1/2014
Uniting Student Musicians and Patients: A Quality Improvement Project.
Schmolze, D.B., Makowski, S., University of Massachusetts Medical School, Senior Scholars Program
http://escholarship.umassmed.edu/ssp/116
1/1/2011
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