Dr. Rader is on Doximity
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Office
11-125 Smilow Center for Translational Research
3400 Civic Center Blvd
Philadelphia, PA 19104Phone+1 215-573-4176
Education & Training
- National Heart Lung and Blood Institute (NHLBI)Post-Doctoral Fellowship, 1998 - 2003
- Yale-New Haven Medical CenterResidency, Internal Medicine, 1984 - 1987
- MCP-Hahnemann College of MedicineClass of 1984
Certifications & Licensure
- PA State Medical License 1993 - 2024
- MD State Medical License 1988 - 1995
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Elected member American Academy of Arts and Science, 2019
- Top doctors Philadelphia Magazine, 2004-2019
- Elected member National Academy of Medicine, 2011
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Publications & Presentations
PubMed
- Deep metabolic phenotyping of humans with protein-altering variants inusing a genome-first approach.Helen Ye Rim Huang, Cecilia Vitali, David Zhang, Nicholas J Hand, Michael C Phillips
JHEP Reports. 2025-01-01 - Bidirectional Risk Modulator and Modifier Variant of Dilated and Hypertrophic Cardiomyopathy in BAG3.Joseph Park, Michael G Levin, David Zhang, Nosheen Reza, Jonathan O Mead
JAMA Cardiology. 2024-12-01 - Mapping rare protein-coding variants on multi-organ imaging traits.Yijun Fan, Jie Chen, Zirui Fan, Julio Chirinos, Jason L Stein
Medrxiv. 2024-11-18
Journal Articles
- The Present and Future JACC Scientific Expert Panel Clinical Genetic Testing for Familial Hypercholesterolemia: JACC Scientific Expert PanelJoshua W Knowles, Seth J Baum, MacRae F Linton, Nathan O Stitziel, Daniel J Rader, Samuel S Gidding, Ray E Hershberger, Zahid S Ahmad, Christie M Ballantyne, ScienceDirect
Press Mentions
- Penn Medicine, Philadelphia: $25 Million Gift Establishes Armellino Center of Excellence for Williams Syndrome at Penn MedicineAugust 8th, 2022
- Daniel J. Rader, M.D., FAHA, of the University of Pennsylvania, to Receive 2021 Research Achievement Award, the American Heart Association’s Highest Scientific AwardNovember 3rd, 2021
- Genetic Variant Linked to HF in People of African American or Latino AncestryDecember 13th, 2019
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Grant Support
- Discovery And Validation Of Novel Loci Associated With HDL FunctionNational Heart, Lung, And Blood Institute2012
- Molecular Regulation Of HDL Metabolism &Reverse Cholesterol TransportNational Heart, Lung, And Blood Institute2010–2012
- HDL METABOLISM: Influence Of Extracellular LipasesNational Heart, Lung, And Blood Institute2009–2012
- Genetics Of Elevated High Density Lipoprotein CholesterolNational Heart, Lung, And Blood Institute2008–2012
- Effects Of Niacin On Lp(A), Oxidized LDL, And Inflammation In The Aim-High TrialNational Heart, Lung, And Blood Institute2008–2012
- Ips-Derived Hepatocytes For Interrogation Of Lipid PhenotypesNational Human Genome Research Institute2011
- Interrogation Of Novel Pathways Regulating VLDL Production And Plasma LipidsNational Heart, Lung, And Blood Institute2011
- Gene Therapy For DyslipidemiasNational Heart, Lung, And Blood Institute2010–2011
- Genetics Of Lipoprotein Metabolism And CVD In CKDNational Heart, Lung, And Blood Institute2009–2011
- Molecular Mechanisms And Pathways Of Novel Genomic Loci Regulating Plasma LipidsNational Heart, Lung, And Blood Institute2009–2010
- Identification Of Causal Variants At Novel GWAS Loci Associated With Lipid TraitsNational Heart, Lung, And Blood Institute2009–2010
- Comprehensive Biomarker Study To Capitalize On Existing GWAS In 10K South AsiansNational Heart, Lung, And Blood Institute2009–2010
- Markers Of The Metabolic Syndrome Linking Type 2 Diabetes And MI In South AsiaFogarty International Center2009–2010
- Molecular Regulation Of HDL Metabolism And Reverse Cholesterol TransportNational Heart, Lung, And Blood Institute2009
- HDL METABOLISM: Influence Of Extracellular LipasesNational Heart, Lung, And Blood Institute2009
- High Density Lipoprotein Metabolism Influence Of Extracellular PhospholipasesNational Heart, Lung, And Blood Institute2007–2008
- Gene Therapy For Dyslipidemia And AtherosclerosisNational Heart, Lung, And Blood Institute2004–2008
- APOE And Regulation Of COX-2 In VsmcsNational Heart, Lung, And Blood Institute2004–2008
- APO A-1 And Reverse Cholesterol Transport In VivoNational Heart, Lung, And Blood Institute2004–2007
- HDL Metabolism Influence Of Extracellular PhospholipasesNational Heart, Lung, And Blood Institute2004–2006
- Antioxidant And Anti-Inflammatory Mechanisms Of HDLNational Heart, Lung, And Blood Institute2003–2006
- Mentored Career Development In Patient Oriented ResearchNational Center For Research Resources2002–2006
- Orally Administered D-4F In Normal Healthy VolunteersNational Center For Research Resources2005
- Microsomal Triglyceride Transfer Protein (MTP) Inhibitor Bms-201038National Center For Research Resources2005
- Mechanism Of Pi-Related Dyslipidemia And Atherosclerosis In HIV SubjectsNational Center For Research Resources2005
- Htg Implitapide StudyNational Center For Research Resources2005
- Hofh Implitapide StudyNational Center For Research Resources2005
- Hefh Implitapide StudyNational Center For Research Resources2005
- Effects Of Rosiglitazone On HDL In Non-Diabetic Patients With Metabolic SyndromeNational Center For Research Resources2005
- Hdl-Cholesterol And Inflammation And Oxidative StressNational Center For Research Resources2004–2005
- A Mechanistic Study Of The Effects Of Rosiglitazone On HDL MetabolismNational Center For Research Resources2004–2005
- Association Of Coronary Calcification With Genetic Markers For AtherosclerosisNational Center For Research Resources1997–2005
- Abnormal Plasma Lipid Levels In Persons At Risk For Premature CHDNational Center For Research Resources1996–2005
- Gordon Research Conference: Lipoprotein Metabolism 2004National Heart, Lung, And Blood Institute2004
- Rosiglitazone On HDL In Non-Diabetic Patients With The Metabolic SyndromeNational Center For Research Resources2004
- Mechanism Of Pi-Related Dyslipidemia And AtherosclerosisNational Center For Research Resources2004
- Bms-201038 In Patients With Homozygous Familial HypercholesterolemiaNational Center For Research Resources2004
- Mechanism Of Pi-Related Dyslipidemia And AtherosclerosisNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2004
- APO A-1 And Reverse Cholesterol Transport In VivoNational Heart, Lung, And Blood Institute2003
- HDL Metabolism:Influence Of Extracellular PhospholipasesNational Heart, Lung, And Blood Institute2000–2003
- Antioxidant And Antiinflammatory Mechanisms Of HDLNational Heart, Lung, And Blood Institute2002
- Soft Gel Containing Plant Stanol Esters To Help Reduce Total And LDL CholesterolNational Center For Research Resources2000–2002
- Gene Therapy For Fh: Evaluation With Lipoprotein Kinetic StudiesNational Center For Research Resources2000–2002
- Ex Vivo Gene Therapy For Familial HypercholesterolemiaNational Center For Research Resources2000–2002
- Chronic Dosing Of Bms-201038 And Hepatic Fat Accumulation, And ReversibilityNational Center For Research Resources2000–2002
- Gene Therapy Of AtherosclerosisNational Heart, Lung, And Blood Institute1999–2002
- Cellular Basis Of Antiatherogenesis By Apolipoprotein ENational Heart, Lung, And Blood Institute1998–2001
- Yogurt Containing Plant Stanol Esters To Help Reduce Total LDL ChlstrNational Center For Research Resources1999–2000
- Effect Of Increasing Doses Of Micronized Fenofibrate On HypertriglycerimediaNational Center For Research Resources1999–2000
- Gene Therapy For Fh--Evaluation With Lipoprotein Kinetic StudiesNational Center For Research Resources1997–1999
- HDL Metabolism--Influence Of Spla2 And SAANational Heart, Lung, And Blood Institute1996–1998
Professional Memberships
- Fellow
- American Society of Human GeneticsMember
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