DanielWeiLinMD

Urology • Seattle, WA

Surgical Oncology

Professor of Urology, University of Washington

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Office
1660 S Columbian Way
Section of Urology 112gu
Seattle, WA 98108
Phone+1 206-764-2265

Fax+1 206-764-2239

Summary

Dr. Daniel Lin is a Urologist based in Seattle, WA, with a subspecialty in Urologic Oncology. He is currently Professor and Interim Chair of Urology, holding the Pritt Family Endowed Chair in Prostate Cancer Research and is the Director of the Institute for Prostate Cancer Research. He underwent his fellowship in Urologic Surgical Oncology at Memorial Sloan Kettering Cancer Center post his residency in Urology at the University of Washington. Dr. Lin currently holds positions at multiple institutions including the Fred Hutchinson Cancer Center, University of Washington School of Medicine, Children’s Hospital and Regional Medical Center, among others. His expertise lies in urologic oncology and robotic prostatectomy and also has multiple publications in various well-established journals. He has participated in several clinical trials and has been the recipient of multiple awards including being listed in America's Top Doctors by Castle Connolly.

Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Urologic Surgical Oncology, 2000 - 2001
University of Washington School of Medicine1998 - 2000
University of WashingtonResidency, Urology, 1994 - 2000
University of Washington School of Medicine1996 - 1998
University of WashingtonInternship, Surgery, 1994 - 1995
Vanderbilt University School of MedicineClass of 1994
Stanford UniversityB.S, Biology, 1989

Certifications & Licensure

AK State Medical License 2022 - 2026
MT State Medical License 2022 - 2026
WA State Medical License 1997 - 2026
NY State Medical License 2000 - 2002
American Board of Urology Urology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2012-2014
America's Top Doctors for Cancer Castle Connolly, 2011-2013
AUA Leadership Program American Urological Association, 2010
Society of Urologic Oncology Young Investigator Award Society of Urologic Oncology, 2009
Best Reviewer 2008 Journal of Urology, 2009
Julian S. Ansell Faculty Teaching Award University of Washington, 2008
American Urologic Association/European Association of Urology Academic Scholar AUA/EAU, 2008
Society of Basic Urologic Research Young Investigator Award Society of Basic Urologic Research, 2007
Joseph F. McCarthy/ACMI Second Prize Essay Western Section American Urological Association, 2006
Service Excellence Award University of Washington, 2006
Yamanouchi First Prize Poster American Urological Association, 2004
Pfizer Scholar in Urology University of Washington, 2000
Earl F. Nation Resident Scholarship Western Section American Urological Association, 1998
James L. Goebel Grand Prize Poster Western Section American Urological Association, 1998
Warren H. Chapman Resident Research Award University of Washington, 1998
Best Resident Paper Northwest Urological Society, 1997, 1998
Alpha Omega Alpha (AOA) Vanderbilt University Medical School, 1994
Undergraduate Teaching Award Department of Biological Science, Stanford University, 1989
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Clinical Trials

Effects of ASA on Prostate Tissue Start of enrollment: 2005 Dec 01
Completed
Not Applicable
Prostate Active Surveillance Study Start of enrollment: 2008 Jul 01
Recruiting
Effects of Sulforaphane on Normal Prostate Tissue Start of enrollment: 2010 Jul 01
Completed
Phase 1, Phase 2
Efficacy and Safety Study of Toremifene Citrate for the Reduction in the Risk of New Bone Fracture Occurrences in Men With Prostate Cancer Start of enrollment: 2011 Mar 01
Withdrawn
Phase 3
Prospective Clinical Utility Study to Assess the Impact of Decipher on Treatment Decisions After Surgery Start of enrollment: 2014 May 01
Completed
Not Applicable
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Publications & Presentations

PubMed

Role of MRI in Active Surveillance of Prostate Cancer.
Meera R Chappidi, Daniel W Lin, Antonio C Westphalen
Seminars in Ultrasound, CT, and MR. 2025-02-01
Editorial Comment.
Meera R Chappidi, Daniel W Lin, Claire M de la Calle
The Journal of Urology. 2025-02-01
1 citations
Polygenic Risk Score and Upgrading in Patients With Prostate Cancer Receiving Active Surveillance.
Louisa B Goss, Menghan Liu, Yingye Zheng, Boya Guo, David V Conti
JAMA Oncology. 2024-12-12

Journal Articles

Re: Effects of short-term finasteride on apoptotic factors and androgen receptors in prostate cancer cells.
Lin DW, Journal of Urology
Treatment of Metastatic Prostate Cancer – How Urologists should Sequence Available Agents.
Mostaghel EA and Lin DW, AUA Update Series
Is Pre-diagnosis PSA Velocity Predictive of the Risk of Death from Prostate Cancer Following Radical Prostatectomy?
Lin DW and Lange PH, Nature Clinical Practice Urology 1: 66
Re: Prostate-specific Antigen Velocity in Men with Total Prostate-Specific Antigen Levels Less Than 4ng/ml.
Lin DW, Journal of Urology 178: 2352-3
Re: Prostate-specific antigen velocity and prostate cancer gleason grade and stage.
Lin DW, Urologic Oncology 25: 529
Re: Active surveillance for prostate cancers detected in three subsequent rounds of a screening trial: characteristics, PSA doubling times, and outcome.
Lin DW, Urologic Oncology 25: 527-8
Re: EPCA-2: A highly specific serum marker for prostate cancer.
Lin DW, Urologic Oncology 25: 528
Re:Adjuvant weekly docetaxel for patients with high risk prostate cancer after radical prostatectomy: a multi-institutional pilot study.
Lin DW, Urologic Oncology 25: 528-9
Re: Marked Gene Transcript Level Alterations Occur Early During Radical Prostatectomy.
Lin DW, Eur Urology 53: 345-6
Re: Role of repeated biopsy of the prostate in predicting disease progression in patients with prostate cancer on active surveillance.
Lin DW, Urologic Oncology 26: 680-1
Re: Preoperative prediction of unifocal, unilateral, margin-negative, and small volume prostate cancer.
Lin DW, Urologic Oncology 26: 681-2
Re: Prostate cancer-specific survival following salvage radiotherapy vs observation in men with biochemical recurrence after prostatectomy.
Lin DW, Urologic Oncology 26: 682-3
Testicular Cancer Guidelines.
Motzer RJ, Agarwal N, Beard C, Bhayani S, Bolger GB, Buyyounouski MK, Carducci MA, Chang SS, Choueiri TK, Gupta S, Hancock SL, Hudes GR, Jonasch E, Kuzel TM, Lau C, Le..., J Natl Compr Canc Netw 10:502-35
Re: Adjuvant radiotherapy for patients with locally advanced prostate cancer – a new standard?
Lin DW, Urologic Oncology
Re: Primary Retroperitoneal Lymph Node Dissection in Patients With Clinical Stage IS Testis Cancer.
Lin DW, Journal of Urology 182:2720
Prostate cancer risk stratification by genotype and PSA.
Wright JL and Lin DW, Nature Reviews Urology 6:641-2
Re: Mortality results from a randomized prostate-cancer screening trial: Andriole GL, Crawford ED, Grubb RL III, et al.
Lin DW, Urologic Oncology 27: 688-9
Re: Improved sensitivity for detecting micrometastases in pelvic lymph nodes by real-time reverse transcriptase polymerase chain reaction (RT-PCR) compared with conven...
Lin DW, Urologic Oncology 27: 689-90
Re: Selective inhibition of CYP17 with abiraterone acetate is highly active in the treatment of castration-resistant prostate cancer: Attard G, Reid AH, A'Hern R, et al.
Lin DW, Urologic Oncology 27: 690-1
Re: Can contemporary transrectal prostate biopsy accurately select candidates for hemi-ablative focal therapy of prostate cancer?: Tareen B, Godoy G, Sankin A, et al.
Lin DW, Urologic Oncology 27: 691
Re: Phase 1 trial of high-dose exogenous testosterone in patients with castration-resistant metastatic prostate cancer: Morris MJ, Huang D, Kelly WK, et al.
Lin DW, Urologic Oncology 27: 692
Value of Urethral Wash after Radical Cystectomy.
Lin DW, Herr HW, Dalbagni G, Journal of Urology 165 (5 suppl): 715A
Phenotypic Heterogeneity in Disseminated Prostate Cancer Tumor Cells: Implications in Epithelial to Mesenchymal Transition.
Koreckij TD, Morgan TM, Lange PH, Coleman I, Coleman R, Ellis WJ, Lin DW, Montgomery B, Lakely B, Morrissey C, and Vessella RL, Journal of Urology 181 (4 suppl): 2086A
Tumor lysis syndrome in a patient with metastatic, androgen independent prostate cancer.
Wright JL, Lin DW, Dewan P, and Montgomery RB, International Journal of Urology 12: 1012-3
Transition Zone PSA Density: Lack of Utility in Prediction of Prostatic Carcinoma.
Lin DW, Gold MH, Ransom S, Ellis WJ, Brawer MK, Journal of Urology 160: 77-82
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Books/Book Chapters

Practical Cases in Urology.
Chapter: Current Management of Testis Cancer
Lin DW and Lange PHEditors: AJ Wein.American Urological Association, Inc
Prostatic Diseases.
Chapter: Epidemiology and Natural History of Prostate Cancer
Page 345 - 356Lin DW and Lange PHEditors: H Lepor.W.B.Saunders Co
Prostate Cancer: Principles and Practice.
Chapter: Tumor Markers in Prostate Cancer
Page 305 - 312Lin DW, Vessella RL, and Lange PHEditors: P Carroll and A D’Amico.W.B. Saunders Co
Management of Prostate Cancer: Advances and Controversies.
Chapter: Anatomical Radical Prostatectomy in the Management of Localized Prostate Cancer
Page 55 - 60Lin DW, Eastham JA, and Scardino PTEditors: KB Cummings.Marcel Dekker, Inc
Mechanisms of Metastasis.
Chapter: Detection, Isolation, and Study of Disseminated Prostate Cancer Cells in the Peripheral Blood and Bone Marrow
Lin DW, Pfitzenmaier J, Ellis WJ, Lange PH, and Vessella RLEditors: C Rinker-Schaeffer.Humana Press, Inc
Prostate Cancer: Principles and Practice.
Chapter: PSA: Practical Applications and Future Prospects
Lin DW and Brawer MKEditors: R Kirby, A Partin, M Feneley, JK Parsons.Martin Dunitz Ltd
Intermittent Androgen Deprivation: Clinical Experience and Practical Applications.
Page 167 - 169Wright JL, Higano CS, and Lin DWEditors: J Smith.Saunders Inc
Role of Post-Chemotherapy Surgery in Germ Cell Tumors.
Page 199 - 217Sim HG, Lange PH, and Lin DWEditors: J Sheinfeld.Saunders Inc
Complications of Urologic Surgery: Prevention and Management.
Chapter: Toxicities of Chemotherapy for Genitourinary Malignancies
Page 117 - 124Montgomery RB and Lin DWEditors: SS Taneja.Elsevier Inc
Comprehensive Textbook of Genitourinary Oncology.
Chapter: Role of Post-Chemotherapy Surgery in Germ Cell Tumors
Sim HG and Lin DWEditors: N Vogelzang, P Scardino.
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Abstracts/Posters

Prostate cancer ≤ 2 cells from the surgical margin predicts biochemical recurrence.
Izard JP, True LD, May PC, Ellis WJ, Lange PH, Lin DW, and Wright JL, Journal of Urology 187 (4 suppl): 1641A
Transurethral Needle Ablation of the Prostate for Treatment of Benign Prostatic Hyperplasia: the University of Washington Experience.
Lin DW, Ellis WJ, American Urological Association
Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) in Bone Marrow Aspirates Following Radical Prostatectomy with Extended Follow-up.
Lin DW, Ellis WJ, Arfman EW, Sohn A, Corey E, Lange PH, Vessella RL, American Urological Association
Salvage Cystoprostatectomy for Treatment of Recurrent Prostate Cancer After Radiation Treatment.
Lin DW, Ellis WJ, Lange PH, American Urological Association
Primary Penile Lymphoma Treated With Surgical Excision.
Lin DW, Krieger JN, Northwest Urological Society, Seattle, WA
Transurethral Needle Ablation of the Prostate for Treatment of Benign Prostatic Hyperplasia: the University of Washington Experience.
Lin DW, Ellis WJ, Northwest Urological Society, Seattle, WA
Efficacy of Acucise Incision on Uretero-Enteral Strictures.
Lin DW, Bush WH, Mayo ME, Northwest Urologic Association, Portland, OR
The NCI Early Detection Research Network (EDRN) Urinary PCA3 Validation Trial.
Wei J, Sanda M, Thompson I, Partin A, Feng Z, Sokoll L, Groskopf J, Brown E, Lotan Y, Kibel A, Busby E, Bidair M, Lin D, Taneja S, and Viterbo R, Journal of Urology 187 (4 suppl): 2206A
Correlation of urine PCA3 score and TMPRS2:ERG score with clinically significant tumor volume in radical prostatectomy specimens: Interim results from a multi-center p...
Davis J, Troncoso P, Meyer S, Day J, Groskopf J, Aubin S, Rodriguez Y, Lin DW, Vakar-Lopez F, Magi-Galluzzi C, and Bergland R, Journal of Urology 187 (4 suppl): 2112A
A randomized pilot study of a reduced-calorie versus standard diet in overweight men with newly diagnosed prostate cancer.
Wright JL, Plymate S, D’Oria-Cameron A, Bain C, Haugk K, Xiao L, Lin DW, Stanford JL, and McTeirnan A, Journal of Urology 187 (4 suppl): 1823A
Serum Percent Free Prostate-Specific Antigen (f-PSA) in Metastatic Prostate Cancer.
Lin DW, Noteboom JL, Ellis WJ, Blumenstein B, Lange PH, Vessella RL, Western Section American Urological Association
Serum glucose is associated with biochemical recurrence in men without diabetes treated for localized prostate cancer.
Wright JL, Gore JL, Porter MP, Lin DW, Hu E, and Zeliadt, Journal of Urology 187 (4 suppl): 177A
of a circulating Microvesicle-based Assay in At-Risk Patients for the Detection of Prostate Cancer.
Kibel A, Andriole G, Lin DW, Vessella RL, Stratton S, Sokoloff M, Spetzler D, and Kuslich C, Journal of Urology 185 (4 suppl): 1924A
Decisional Conflict Varies by Institution for Men Making Treatment Decisions for Localized Prostate Cancer.
Berry D, Hong F, Halpenny B, Wolpin S, Lober W, Russell K, Ellis WJ, Davison J, Barsevick A, Yang C, Lin DW, and Bennett G, Journal of Urology 185 (4 suppl): 1001A
A Randomized Pilot Study to Assess Anxiety Related to Distributing a Prostate Cancer Treatment Decision Aid Prior to Biopsy.
Zeliadt S, Bonner L, Trivedi R, Kimmie C, Hannon P, Vu T, Zipperer C, Porter M, and Lin DW, Journal of Urology 185 (4 suppl): 627A
Positive Surgical Margins at Radical Prostatectomy: National Averages Within PSA and Gleason Strata.
Salazar M, Chatterjee S, Lin DW, and Wright JL, Journal of Urology 185 (4 suppl): 154A
The Cost-Effectiveness of the Double Benefit of 5-Alpha-Reductase Inhibitor (5ARI) Chemoprevention on Both Undisclosed Genitourinary Symptoms and Prostate Cancer.
Westerman S, Zeliadt S, Gore JL, and Lin DW, Journal of Urology 185 (4 suppl): 71A
AMACR Polymorphisms, Dietary Intake and Prostate Cancer Risk.
Wright JL, Neuhouser ML, Lin DW, Kwon EM, Feng Z, Ostrander EA, and Stanford JL, Journal of Urology 183 (4 suppl): 2055A
The Effect of Demographic and Clinical Factors on the Relationship Between BMI and PSA Levels.
Wright JL, Lin DW, and Stanford JL, Journal of Urology 183 (4 suppl): 2059A
Diethylstilbestrol and docetaxel: a phase II study in patients with metastatic androgen independent prostate cancer.
Montgomery B, Lin DW, Ryan C, Garzotto M, and Beer TM, Multidisciplinary Prostate Cancer Symposium, Orlando, FL
Progression and treatment in a multi-institutional, prospective active surveillance study: Results from Canary Prostate Active Surveillance Study (PASS).
Lin DW, Newcomb L, Ellis W, Gleave M, Thompson I, Brooks J, Nelson P, Sanda M, Lance R, Wei J, Feng Z, Carroll P, and Canary/EDRN Investigators, American Urological Association 2012 Annual Meeting, Atlanta, GA
Toremifene Demonstrates Reduction in Fracture risk in Men Less Than 80 Years of Age on Androgen Deprivation Therapy.
Lin DW, Marks LS, Morton RA, Steiner MS, and Brawer MK, Western Section American Urological Association, Hawaii
The Effect of Toremifene on PSA Progression-Free Survival in Castrate Men with Detectable Baseline PSA Levels.
Lin DW, Barnett G, Brawer MK, Smith M, Morton R, Steiner M, and Yu E, Northwest Urological Society Scientific Program, Bellevue, WA
Global gene expression changes in human prostate tissue in response to dietary intervention.
Lin DW, Neuhouser ML, Schenk JM, Coleman IM, Hawley S, Gifford D, Hung H, Knudsen BS, Nelson PS, and Kristal AR, Western Section American Urological Association, Maui, HI
Quality of Life in Young Men after Radical Prostatectomy: Results from the CAPSURE Registry.
Wright JL, Lin DW, Cowan JE, DuChane J, Carroll PR, and Litwin MS, American Society of Clinical Oncology, 2006 Annual Meeting, Atlanta, GA
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Lectures

Beyond PSA: Utility of Novel Tumor Markers in the Setting of Elevated PSA.
American Urological Association 2008 Annual Meeting, Orlando, FL
Adjuvant Chemohormonal Therapy in High Risk Prostate Cancer: a Point-Counterpoint Debate.
Northwest Urological Society Annual Meeting, Spokane, WA
Progress and Promise in Prostate Cancer Research.
VA R&D Research Colloquium, Seattle, WA
Everything You Want To Know About Prostate Cancer in 2007.
American Association of Pediatric Ophthalmology and Strabismus Annual Meeting, Seattle, WA
Screening and Diagnosis of Prostate Cancer.
Providence Saint Joseph Medical Center Grand Rounds, Burbank, CA
Clinical Scenarios and Treatment Strategies for Advanced Prostate Cancer in Younger Men.
Multiple locations, 2006
Prostate Anatomy and Evaluation of Lower Urinary Tract Symptoms.
Men’s Health Update CME Course, Seattle, WA
Prostate Carcinogenesis.
Men’s Health Update CME Course, Seattle, WA
Diagnosis and Management of Clinically Localized Prostate Cancer 2007.
Seattle Cancer Care Alliance Outreach Symposium, Great Falls, MT
Management of High Risk Prostate Cancer.
Urology Research Forum, Charles University, Prague, Czechoslovakia
Prostate Cancer Update 2006.
Evergreen Hospital Grand Rounds, Kirkland, WA
Non-Muscle Invasive Bladder Cancer: AUA Management Guidelines.
American Urological Association 2008 Annual Meeting CME Course Faculty, Orlando, FL
Adjuvant Treatment Strategies for High-Risk Post-Prostatectomy Prostate Cancer: Emerging Data and New Directions.
Multiple locations, 2007
Risk Stratification, Mechanisms of Recurrence, and Adjuvant Treatment Strategies for High-Risk Post-Prostatectomy Prostate Cancer.
Scott Department of Urology Grand Rounds, Baylor University School of Medicine, Houston, TX
Prostate Cancer Screening and Rationale For/Against Early Detection of Localized Prostate Cancer.
Annual Advances in Family Practice and Primary Care, Seattle, WA
Prostate Cancer Screening and Evaluation and Treatment of Newly Diagnosed Prostate Cancer.
Puget Sound Health Care System Prostate Cancer Awareness Month Symposium, Seattle, WA
The Effects of Sulforaphane on Normal Human Prostate Cells: Mechanisms of Cancer Prevention and Rationale for Clinical Trial.
Pacific NW Prostate Cancer SPORE External Advisory Board Symposium, Seattle, WA
Beyond PSA: Utility of Novel Prostate Cancer Markers in Advanced Disease.
Moffitt Cancer Center Advanced Prostate Cancer Collaboration, Tampa, FL
Progress and Promise in Prostate Cancer.
Albany VA Grand Rounds, Albany, NY
The Role of Peri-Operative Chemotherapy in High-Risk Prostate Cancer: PUNCH and VA Surgical Trials.
3rd Annual John R. Murren Oncology Symposium, Las Vegas, NV
Disseminated Tumor Cells: Clinical Applications, Prognostic Significance, and Future Directions in Prostate Cancer Patients.
American Society of Clinical Oncology 2005 Annual Meeting: Invited abstract discussant, Orlando, FL
Screening, Detection, and Staging of Prostate Cancer.
5th Annual North Puget Sound Oncology Symposium, Mount Vernon, WA
Detection and Isolation of PSA Positive Epithelial Cells by Enrichment: Comparison to Standard RT-PCR, Clinical Relevance, and Initial Characterization in Prostate Can...
InterProstate SPORE Meeting, Chicago, IL
Prostate Cancer Screening, Detection, and Treatment.
Auburn Regional Medical Center Grand Rounds, Auburn, WA
Recent Advances in the Treatment of Hormone Refractory Prostate Cancer.
80th Annual Western Section American Urological Association Meeting, San Diego, CA
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Press Mentions

Why Men Should Be Screened for the ‘Breast Cancer Gene’August 7th, 2024
SCCA’s Immunotherapy Leaders Featured at the American Society of Clinical Oncology (ASCO) Annual MeetingMay 31st, 2018
Popular Prostate Cancer Therapy Is Short, Intense and UnprovenMarch 20th, 2017
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Grant Support

In Vivo Effects Of Sulforaphane Supplementation On Normal Human ProstateNational Cancer Institute2009–2011
In Vivo Molecular Effects Of Prostatic COX-2 InhibitionNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2007