DanielDavidBikleMD

PubMed

• 198 citations
  Calcium regulation of keratinocyte differentiation.
  Daniel D. Bikle, Zhongjian Xie, Chia-Ling Tu
  Expert Review of Endocrinology & Metabolism. 2012-07-01
• 559 citations
  Skeletal and Extraskeletal Actions of Vitamin D: Current Evidence and Outstanding Questions.
  Roger Bouillon, Claudio Marcocci, Geert Carmeliet, Daniel D. Bikle, John H. White
  Endocrine Reviews. 2019-08-01
• 1008 citations
  Vitamin D Metabolism, Mechanism of Action, and Clinical Applications
  Daniel D. Bikle
  Chemistry & Biology. 2014-03-20

Journal Articles

• Skeletal and Extra-Skeletal Actions of Vitamin D: Current Evidence and Outstanding Questions  
  John Bilezikian, Daniel Bikle, Endocrine Reviews
• Determination of Free 25(OH)D Concentrations and Their Relationships to Total 25(OH)D in Multiple Clinical Populations  
  Jennifer Lai, Janice B Schwartz, Michael Holick, Eric Orwoll, Daniel Bikle, The Journal of Clinical Endocrinology and Metabolism
• The mechanism of action of vitamin D in the intestine.  
  Bikle DD, Morrissey RL, Zolock DT, Am J Clin Nutr
• The effects of 1 hydroxyvitamin D3 on the rachitic chick intestine: a comparison to the effect of 1,25 dihydroxyvitamin D3.  
  Bikle DD, Empson RN Jr, Morrissey RL, Zolock DT, Bucci TJ, Herman RH, Pechet MM, Calcif Tissue Int
• Calcium accumu¬la¬tion by chick intestinal mitochondria: regulation by vitamin D3 and 1,25 dihydroxy vitamin D3.  
  Bikle DD, Askew EW, Zolock DT, Morrissey RL, Herman RH, Biochim Biophys Acta
• Influence of cyclo¬heximide and 1,25 dihydroxyvitamin D3 on mitochondrial and vesicle minera¬liza-tion in the intestine.  
  Morrissey RL, Zolock DT, Mellick PW, Bikle DD, Cell Calcium
• Prolactin but not growth hormone stimulates 1,25 dihydroxyvitamin D3 production by chick renal preparations in vitro.  
  Bikle DD, Spencer EM, Burke WH, Rost CR, Endocrinology
• Studies of chick renal mitochondrial 25 hydroxyvitamin D3 24 hy¬droxylase.  
  Bikle DD, Biochim Biophys Acta
• In vitro stimulation of 25 hydroxy¬chole¬cal¬ciferol 1 hydroxy¬lation by parathyroid hormone in chick kidney slices: evi¬dence for a role of 3'5' cyclic AMP.  
  Rost CR, Bikle DD, Kaplan RA, Endocrinology
• Pharmaco¬kinetics and pharmacodynamics of 1,25 dihydroxyvitamin D in the chick.  
  Bikle DD, Peck CC, Holford NHG, Zolock DT, Morrissey RL, Endocrin¬ology
• Calcium potentiates the cyclic nucleotide and phospha¬turic response to parathyroid hormone infusion.  
  Bikle DD, Herman RH, J Clin Endocrinol Metab
• The adaptive response of humans to changes in dietary calcium: relationship between vitamin D regulated intestinal function and serum 1,25 dihydroxy vitamin D levels.  
  Bikle DD, Herman RH, Hull S, Hagler L, Harris D, Halloran B, Gstroenterology
• Calcium flux across chick duodenal brush border membrane vesicles: regulation by 1,25 dihydroxyvitamin D.  
  Bikle DD, Munson S, Zolock DT, Endocrinology
• Simulating certain aspects of hypogravity: effects on bone maturation in the nonweight bearing skeleton.  
  Simmons DJ, Grazmah B, Russell JE, Waller WV, Bikle DD, Morey ER, Aviation Space Environ
• The relationship of membrane fluidity to calcium flux in chick intestinal brush border membranes.  
  Bikle DD, Whitney J, Munson S, Endocrinology
• Effects of simulated weightlessness on bone mineral metabolism.  
  Globus RK, Bikle DD, Morey Holton E, Endocrinology
• Calmodulin may mediate 1,25 dihydroxy vitamin D stimulated intestinal calcium transport.  
  Bikle DD, Munson S, Chafouleas J, FEBS Lett
• Acute but not chronic metabolic acidosis disturbs 25 hydroxyvitamin D metabolism.  
  Cunningham J, Bikle DD, Avioli LV, Kidney Int
• Measurement of 25,26 dihydroxyvitamin D: the importance of the configuration of the C 25 hydroxyl group.  
  Bikle DD, Halloran BP, Whitney JO, Hollis BW, Biochemistry
• Separation of isotopically labeled vita¬min D metabolites by high performance liquid chromatography.  
  Halloran BP, Bikle DD, Whitney JO, J Chromatogr
• Free 1,25 dihydroxyvitamin D levels in serum from normal subjects, pregnant subjects, and subjects with liver dis¬ease.  
  Bikle DD, Gee E, Halloran B, Haddad JG, J Clin Invest
• Bone disease in alcohol abuse.  
  Bikle DD, Genant HK, Cann CE, Recker RR, Halloran BP, Strewler GJ, Ann Intern Med
• Serum protein binding of 1,25 dihydroxyvi¬tamin D: a reevaluation by direct measurement of free metabolite levels.  
  Bikle DD, Siiteri PK, Ryzen E, Haddad JG, Gee E, J Clin Endocrinol Metab
• 1,25 dihydroxyvitamin D increases calmodulin binding to specific proteins in the chick duodenal brush border membrane.  
  Bikle DD, Munson S, J Clin Invest
• The temporal response of bone to unloading.  
  Globus RK, Bikle DD, Morey Holton E, Endocrinology
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Books/Book Chapters

• Endotext.Org. 
  Chapter: Vitamin D: Production, Metabolism, and Mechanisms of Action 
  Bikle DDEditors: LJ DeGroot.
• Vitamin D: Chemical, Biochemical, and Clinical Endocrinology of Calcium Metabolism. 
  Chapter: Calcium transport by chick duodenal brush border membrane vesi¬cles 
  Page 313 - 315Bikle DDEditors: Norman AW, Schaefer K, Herrath DV, Grigoleit HG.de Gruyter, New York
• Advances in Internal Medicine. 
  Chapter: The vitamin D endocrine system 
  Page 45 - 71Bikle DDEditors: Stollerman GH.Year Book Medical Publishers
• Vitamin D: Basic Research and its Clincial Applications. 
  Chapter: Is 1,24,25(OH)3D the principal intestinal metabolite in vitamin D repleted chicks? 
  Page 727 - 730Bikle DD, Morrissey RL, Zolock DT, Herman RHEditors: Norman AW, Schaefer K, Herrath DV, Grigoleit HG, Coburn JW, DeLuca HF, Mawer EB, Suda T.de Gruyter, New York
• Vitamin D: Basic Research and its Clinical Applications. 
  Chapter: Meaning of nonparallel 1,25(OH)2D mediated response relationships in intestine and bone to dose and time 
  Page 639 - 642Zolock DT, Morrissey RL, Bikle DDEditors: Norman AW, Schaefer K, Herrath DV, Grigoleit HG, Coburn JW, DeLuca HF, Mawer EB, Suda T.de Gruyter, New York
• Vitamin D: Bio¬chemical, Chemical and Clinical Aspects Related to Calcium Metabolism. 
  Chapter: The effect of 1,25 DHCC on the calcium accumulation, calcium transport, and calcium binding protein in the presence and absence of cycloheximide 
  Page 345 - 347Zolock DT, Morrissey RL, Bikle DDEditors: Norman AW, Coburn JW, DeLuca HF, Fraser D, Grigoleit HG, Schaefer K.de Gruyter, Elmsford, NY
• ) Vitamin D: Biochemical, Chemical and Clinical Aspects Related to Calcium Metabolism. 
  Chapter: 1,25 dihydroxycholecalciferol stimulation of calcium binding protein specific m RNA 
  Page 227 - 229Charles MA, Martial J, Zolock D, Morrissey R, Bikle D, Baxter JEditors: Norman AW, Coburn JW, DeLuca HR, Fraser D, Grigoleit HG, Schaefer K.de Gruyter, Elmsford, NY
• Vitamin D: Biochemical, Chemical and Clinical Aspects Related to Calcium Metabolism. 
  Chapter: The dissociation of 1,25(OH)2D3 induced CaBP production and alkaline phosphatase activity from cal¬cium transport by actinomycin Dcontinuedandcycloh¬eximide 
  Page 223 - 225Bikle DD, Zolock DT, Morrissey RL, Herman RHEditors: Norman AW, Coburn JW, DeLuca HF, Fraser D, Grigoleit HG, Schaefer K.de Gruyter, Elmsford, NY
• Carafoli E. 
  Chapter: Calcium and nonvesicular secretion in the kidney: calcium and mitochondrial functions 
  Page 111 - 121Rasmussen H, Bikle DDEditors: Calcium Transport in Contrac¬tion and Secretion.North Holland Publishing Co
• Epithelial Calcium and Phosphate Transport: Molecular and Cellular Aspects. 
  Chapter: The role of calmodulin in 1,25 dihydroxyvitamin D regulation of calcium transport across the intestinal brush border membrane 
  Page 193 - 198Bikle DD, Munson S, Chafouleas JGEditors: Bronner F, Peterlik M.Liss, New York
• Quick Look Pharmacology. 
  Chapter: Drugs for altering calcium homeostasis: treatment of osteoporosis 
  Page 156 - 157Bikle DDEditors: RB Raffa.Fence Creek Publishing, Madison, CT
• Progress in HPLC. 
  Chapter: Use of HPLC and On line Radioactivity Monitoring in Studies o f Vitamin D Metabolism 
  Page 93 - 127Pillai S, Gee E, Bikle DDEditors: Reich A, Lucus-Reich S, Parvez S Binh Thanh: title: Progress in HPLC.Utrecht, International Science
• Handbook of diet, nutrition and the skin. 
  Chapter: The skin and vitamin D 
  Page 92 - 113Bikle DDEditors: VR Preedy.Wageningen Academic Publishers
• Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 
  Chapter: Vitamin D: Production, metabolism, mechanism of action, and clinical requirements 
  Bikle DD, Adams J, Christakos SEditors: C Rosen.Edition 8th,
• Vitamins and the Immune System. 
  Chapter: Vitamin D Regulation of Immune Function IN Vitamins and Hormones 
  Bikle DDEditors: G Litwack.
• Vitamin D and Cancer in Bioactive foods and extracts: Cancer prevention and treatment. 
  Page 481 - 495Teichert A and Bikle DDEditors: Watson RR and Preedy VR.CKRC Press, Taylor and Francis Group
• Vitamin D: Physiology, Molecular Biology, and Clinical Applications. 
  Chapter: Extra renal synthesis of 1,25-dihydroxyvitamin D and its health implications 
  Page 277 - 295Bikle DDEditors: M Holick.Humana Press
• Vitamin D: Gene regulation, structure-function analysis and clinical application. 
  Chapter: Regulation of calmodulin binding to the ATP extractable 110k D protein from chicken duodenal brush border 
  Page 691 - 69227. Kaune R, Munson S, Bikle DDEditors: AW Norman, R Bouillon, M Thomasset.Walter de Gruyter, Berlin
• Alcohol induced bone disease in osteoporosis 1990. 
  Chapter: Handelstrykkeriet Aalborg 
  Page 1544 - 1551Bikle D, Stesin A, Halloran B, Steinbach L, Recker REditors: C Christiansen and K Overgaard.Denmark
• Vitamin D endocrine system: Structural, biological, genetic, and clinical aspects. 
  Chapter: Requirement of vitamin D receptor in epidermal differentiation and hair follicle recycling 
  Page 623 - 626Xie Z, Komuves L, Ng DC, Leary C, Yoshizawa T, Kato S, Bikle DDEditors: AW Norman, R Bouillon, M Thomasset.Riverside, California
• Vitamin D endocrine system: Structural, biological, genetic, and clinical aspects. 
  Chapter: The role of phospholipase C-?1 in 1?,25-dihydroxyvitamin D regulated keratinocyte differentiation 
  Page 597 - 604Xie Z, Bikle DDEditors: AW Norman, R Bouillon, M Thomasset.Riverside, California
• Vitamin D Chemistry, Biology and Clinical Applications of the Steroid Hormone. 
  Chapter: Synergistic induction by 1,25-Dihyroxyvitamin D3 and all-trans retinoic acid of the human phospholipase C- 1 gene 
  Xie Z, Bikle DDEditors: Anthony W. Norman, Roger Bouillon, and Monique Thomasset.
• Vitamin D Chemistry, Biology and Clinical Applications of the Steroid Hormone. 
  Chapter: Molecular mechanisms underlying 1,25(OH)2 D regulation of epidermal differentiation 
  Bikle DDEditors: Anthony W. Norman, Roger Bouillon, and Monique Thomasset.
• Hormonal Regulation of Bone Mineral Metabolism. 
  Chapter: Vitamin D: new actions, new analogs, new therapeutic potential: update 1995 
  Page 77 - 83Bikle DDEditors: DD Bikle and A Negro-Villar.Endocrine Society Press, Bethesda
• Vitamin D, a pluripotent steroid hormone:structural studies,molecular endocrinology,and clinical applications. 
  Chapter: 1,25(OH)2D modulated calcium induced keratinocyte differentiation: from the culture dish to the psoriatic patient 
  Page 568 - 575Bikle DDEditors: AW Norman, R Bouillon, M Thomasset.pref Walter de Gruyter, Berlin (New York)
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Lectures

• Vitamin D. 
  Meeting report from the 26th Annual Meeting of the American Society fro Bone and Mineral Research