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Office
5132 Rockville Pike
Rm 4E
Bethesda, MD 20892Phone+1 301-496-5093Fax+1 301-594-1290
Education & Training
- Boston University Medical CenterResidency, Internal Medicine, 1984 - 1987
- Harvard Medical SchoolClass of 1984
Certifications & Licensure
- MD State Medical License 1989 - 2026
- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 2003
Clinical Trials
- Improved Methods of Cell Selection for Bone Marrow Transplant Alternatives Start of enrollment: 1996 Mar 18
- Screening for Hematology Branch Protocols Start of enrollment: 1996 Dec 31
- A Pilot Study of the Thrombopoietin-Receptor Agonist Eltrombopag in Refractory Aplastic Anemia Patients Start of enrollment: 2009 May 29
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Publications & Presentations
PubMed
- 71 citationsDynamics of HSPC repopulation in nonhuman primates revealed by a decade-long clonal-tracking study.Sanggu Kim, Namshin Kim, Angela P. Presson, Mark E. Metzger, Aylin C. Bonifacino
Cell Stem Cell. 2014-04-03 - 20 citationsHigh efficiency restriction enzyme-free linear amplification-mediated polymerase chain reaction approach for tracking lentiviral integration sites does not abrogate re...Chuanfeng Wu, Alexander Jares, Thomas Winkler, Jianjun Xie, Jean-Yves Metais
Human Gene Therapy. 2013-01-01 - 4 citationsImpact of CRISPR/HDR editing versus lentiviral transduction on long-term engraftment and clonal dynamics of HSPCs in rhesus macaques.Byung-Chul Lee, Ashley Gin, Chuanfeng Wu, Komudi Singh, Max Grice
Cell Stem Cell. 2024-04-04
Abstracts/Posters
- An All Antibody Approach for Conditioning Bone Marrow for Hematopoietic Stem Cell Transplantation with Anti-cKIT and Anti-CD47 in Non-Human PrimatesCynthia E. Dunbar, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Lectures
- Eltrombopag Improves Hematopoiesis in Patients with Low to Intermediate-2 Risk Myelodysplastic Syndrome(MDS)2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
- Modeling Human Paroxysmal Nocturnal Hemoglobinuria Via CRISPR/Cas9 HSPC Gene Editing in Non-Human Primate2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Press Mentions
- Gene Therapy for Rare Brain Disease Effective, but Comes with Blood Cancer RiskOctober 9th, 2024
- High-Dose MTX Does Not Reduce CNS Relapse in Pediatric ALLDecember 11th, 2022
- Ash 2022 – Argenx Faces Vyvgart QuestionsDecember 10th, 2022
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Grant Support
- The Rhesus Macaque As A Preclinical Model For Induced Pluripotent Stem CellsNational Heart, Lung, And Blood Institute2010–2011
- Retroviral Mediated Gene Transfer Into Primate Hematopoietic CellsNational Heart, Lung, And Blood Institute2010–2011
- Enhancement Of Hematopoietic Stem Cell Mobilization And EngraftmentNational Heart, Lung, And Blood Institute2010–2011
- Developing Efficient And SAFE Gene Transfer To Primate Hematopoietic Stem CellsNational Heart, Lung, And Blood Institute2010–2011
- Gene Transfer And Ex Vivo Manipulation Of Stem CellsNational Heart, Lung, And Blood Institute2009
- Gene Transfer And Ex Vivo Manipulation Of Hematopoietic CellsNational Heart, Lung, And Blood Institute1998–2008
- Gene Transfer And Ex Vivo Manipulation Of HematopoieticNational Heart, Lung, And Blood Institute2001–2006
- Gene Transfer To Hematopoietic Progenitor, Stem, And Stromal CellsNational Heart, Lung, And Blood Institute1995–1997
- Gene Transfer To Human Hematopoietic Progenitor, Stem, And Stromal CellsNational Heart, Lung, And Blood Institute1994
- Preclinical And Clinical Gene Transfer To Human Hematopoietic Stem CellsNational Heart, Lung, And Blood Institute1992–1993
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