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Office
401 E Chestnut St
Suite 310
Louisville, KY 40202Phone+1 502-584-8563Fax+1 502-562-6196
Education & Training
- University of MinnesotaFellowship, Gastroenterology, 1975 - 1977
- UPMC Medical EducationResidency, Internal Medicine, 1972 - 1975
- University of Tennessee Health Science Center College of MedicineClass of 1972
- Earlham CollegeBA, 1968
Certifications & Licensure
- KY State Medical License 1982 - 2025
- OH State Medical License 2005 - 2006
- MN State Medical License 1976 - 1982
- PA State Medical License 1973 - 1976
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Gastroenterology
Awards, Honors, & Recognition
- NIH Mark Keller Honorary Lecture honoree NIH, 2014
- Fellow American Association for the Study of Liver Diseases, 2014
- Elizabeth Hurlock Beckman Award for Mentoring 2013
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Clinical Trials
- Efficacy Study of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis Start of enrollment: 2013 Sep 01
- Novel Therapies in Moderately Severe Acute Alcoholic Hepatitis Start of enrollment: 2013 Aug 01
- Trial of Anakinra (Plus Zinc) or Prednisone in Patients With Severe Alcoholic Hepatitis Start of enrollment: 2020 Jul 10
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Publications & Presentations
PubMed
- 32 citationsPhosphodiesterase 4b expression plays a major role in alcohol-induced neuro-inflammationDiana Avila, Scott A. Myers, Jingwen Zhang, Giorgi Kharebava, Craig J. McClain
Neuropharmacology. 2017-10-01 - 57 citationsEnhanced PDE4B expression augments LPS-inducible TNF expression in ethanol-primed monocytes: relevance to alcoholic liver disease.Leila Gobejishvili, Shirish Barve, Swati Joshi-Barve, Craig J. McClain
American Journal of Physiology. Gastrointestinal and Liver Physiology. 2008-08-07 - 60 citationsClinical implications of oxidative stress and antioxidant therapyGerald W. Dryden, Ion V. Deaciuc, Gavin E. Arteel, Craig J. McClain
Current Gastroenterology Reports. 2005-08-01
Journal Articles
- Copper-Fructose Interactions: A Novel Mechanism in the Pathogenesis of NAFLDMiriam B Vos, Craig J McClain, MDPI
- Nutrition in Patients with CirrhosisCraig McClain, MD, National Institutes of Health
- Simultaneous Quantification of Straight-Chain and Branched-Chain Short Chain Fatty Acids by Gas Chromatography Mass SpectrometryCraig McClain, Craig McClain, ScienceDirect
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Books/Book Chapters
Abstracts/Posters
- Special Topic Issue: Liver and Pancreatic Diseases: Consequences of Chronic Alcoholic ConsumptionSinger MV, Dooley S, McClain CJ, Zakhari S, Dig Dis, Falk Workshop, Freiburg, 1/1/2010
- National Consensus Counsel on OTC AnalgesicsMcClain CJ, Ft. Lauderdale, Florida, 1/1/1993
- International Cytokine Research ConferenceMcClain CJ, Hilton Head, SC, 1/1/1987
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Lectures
- CAM and GI DiseaseChicago, Illinois - 1/1/2001
- Nutrition Support and Liver Disease: Traditional and Nontraditional ApproachesLouisville, Kentucky - 1/1/2001
- Monocytes and ALDMontreal, Canada - 1/1/2001
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Other
- Acrolein in ALDChen, J
1/1/2015 - Liver, Environmental Toxins and EpigeneticsGhare, S
1/1/2015 - Liver TransplantationFrimodig, J
1/1/2015 - Join now to see all
Press Mentions
- UofL and Robley Rex VA Medical Center Partnership Leads to New State-of-the-Art Multiphoton Microscopes for Exposure StudiesNovember 22nd, 2022
- University of Louisville Receives NIH Funding to Support Research into Liver-Related IllnessJune 21st, 2021
- UofL Receives $11.3 Million Grant for Liver Research CenterJune 21st, 2021
Grant Support
- Alcohol, Proteasome Dysfunction In Liver InjuryVeterans Affairs2011–2012
- Summer Environmental Health Sciences Training ProgramNational Institute Of Environmental Health Sciences2011–2012
- Cyclic AMP, Cytokine Modulation And Alcoholic Liver DiseaseNational Institute On Alcohol Abuse And Alcoholism2009–2011
- The Role Of Alcohol In HIV Therapy HepatotoxicityNational Institute On Alcohol Abuse And Alcoholism2008–2011
- University Of Louisville Bioinformatics Faculty Recruitment For EpigeneticsNational Institute On Alcohol Abuse And Alcoholism2009–2010
- Biomarkers For SteatohepatitisNational Institute On Alcohol Abuse And Alcoholism2009–2010
- Alcohol Liver Disease And Alcohol-Nutrient InteractionsNational Institute On Alcohol Abuse And Alcoholism2008–2010
- Administrative CoreNational Institute On Alcohol Abuse And Alcoholism2008–2010
- TNF And Mitochondrial Dysfunction In ALDNational Institute On Alcohol Abuse And Alcoholism2006–2010
- S-Adenosylhomocysteine And S-Adenosylmethionine In Alcoholic Liver DiseaseNational Institute On Alcohol Abuse And Alcoholism2005–2010
- Mechanisms Of S-Adenosylmethionine In NASHNational Institute Of Diabetes And Digestive And Kidney Diseases2005–2009
- Planning Grant For Louisville Clinical And Translational Science AwardNational Center For Research Resources2006
- Tumor Necrosis Factor And Alcoholic Liver DiseaseNational Institute On Alcohol Abuse And Alcoholism2001–2005
- Alcohol Liver Disease And S-AdenosylmethionineNational Institute On Alcohol Abuse And Alcoholism2001–2005
- A.S.P.E.N. Research Workshop On Functional FoodsNational Institute Of Diabetes And Digestive And Kidney Diseases2002
- Alcohol, Nutrition, And ImmunomodulationNational Institute On Alcohol Abuse And Alcoholism2000
- Alcohol, Nutrition, And ImmunomodulationNational Institute On Alcohol Abuse And Alcoholism1996–2000
- Pharmacokinetics And Pharmacodynamics Of Procysteine In Liver DiseaseNational Center For Research Resources1997–1999
- Alcohol Liver Disease And S AdenosylmethionineNational Institute On Alcohol Abuse And Alcoholism1998
- Altered Hepatic Metabolism Following Head InjuryNational Institute Of Neurological Disorders And Stroke1996–1998
Professional Memberships
- Fellow
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