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Office
200 Lothrop St
Ste F-158
Pittsburgh, PA 15213Phone+1 412-647-6781Fax+1 412-647-8447
Summary
- Dr. Hadjipanayis is a board-certified neurosurgeon who has devoted his entire career to the treatment of brain tumor patients. He completed his neurosurgical residency and graduate Ph.D. training at the University of Pittsburgh School of Medicine with additional neurosurgical oncology training at the University of California San Francisco. He is the inaugural L. Dade Lunsford Professor of Neurological Surgery at UPMC and will serve as Executive Vice-Chairman for the Dept. of Neurological Surgery. Dr. Hadjipanayis has taken over as Director of the UPMC Center for Image-Guided Neurosurgery from his mentor Dr. L. Dade Lunsford. He will also serve as Co-Director of the newly formed UPMC Brain Tumor Center at the Hillman Cancer Center. Dr. Hadjipanayis directs the Brain Tumor Nanotechnology Laboratory in the Hillman Cancer Center and has been the principal investigator of multiple clinical trials and university-, private foundation-, and NIH-funded grants focused on brain tumors. He was recently recruited back from the Icahn School of Medicine at Mount Sinai in New York City where he served as the Chairman of Neurosurgery at Mount Sinai Union Square/Beth Israel and the Director of Neurosurgical Oncology for the Mount Sinai Health System. Dr. Hadjipanayis has focused much of his career on innovation, translational research, and intraoperative technology development. In 2011, Dr. Hadjipanayis was the first to use 5-ALA (Gleolan) and perform fluorescence-guided surgery (FGS) in the US and helped lead the FDA approval of Gleolan for glioma surgery in June 2017. He has also led the development of a voice-controlled robotic-assisted exoscope for neurosurgery. He is an elected member of the American Academy of Neurological Surgeons and the Society of Neurological Surgeons (SNS). Dr. Hadjipanayis has been a tireless brain tumor advocate serving on the nonprofit boards of the Southeastern Brain Tumor Foundation (SBTF) and StacheStrong.
Education & Training
- UPMC Medical EducationResidency, Neurological Surgery, 1999 - 2006
- University of Pittsburgh School of MedicinePost-Doctoral Fellowship, 2003 - 2005
- University of Pittsburgh School of MedicinePh.D., Biochemistry/Molecular Genetics, 2005
- UPMC Medical Education (Pittsburgh)Residency, Surgery, 1998 - 1999
- Sidney Kimmel Medical College at Thomas Jefferson UniversityClass of 1998
- University of DelawareBA, Major: Medical Scholar's Program, Minor: Medical Humanities, Magna Cum Laude, 1990 - 1994
Certifications & Licensure
- FL State Medical License 2020 - Present
- NY State Medical License 2015 - 2026
- PA State Medical License 2022 - 2024
- GA State Medical License 2007 - 2016
- American Board of Neurological Surgery Neurological Surgery
Awards, Honors, & Recognition
- Reviewer Excellence Award Neurosurgery, 2015
- Best Poster, Nanomedicine Translational Molecular Imaging Institute, Icahn School of Medicine at Mount Sinai, 2015
- Fellow Robert Woodruff Leadership Academy, 2014
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Clinical Trials
- More Complete Removal of Malignant Brain Tumors by Fluorescence-Guided Surgery Start of enrollment: 2015 Nov 01
- Laser Ablation of Abnormal Neurological Tissue Using Robotic NeuroBlate System Start of enrollment: 2015 Oct 01
- 5-Aminolevulinic Acid (5-ALA) to Enhance Visualization of Malignant Tumor Start of enrollment: 2016 May 01
Publications & Presentations
PubMed
- Primary and salvage radiosurgery for neurofibromatosis type 2-associated meningiomas.Zhishuo Wei, Suchet Taori, Mishika Mehta, Shalini G Jose, Diego D Luy
Journal of Neurosurgery. 2024-11-22 - Hearing preservation outcomes using direct cranial nerve eight and auditory brainstem response neuromonitoring in the resection of vestibular schwannomas.Dayna C Sloane, Mohammed Nuru, Nathan C Pecoraro, Rob Hand, Oleksandr Strelko
Journal of Neurosurgery. 2024-11-01 - Barriers to T Cell Functionality in the Glioblastoma Microenvironment.Noor E Nader, Stephen C Frederico, Tracy Miller, Sakibul Huq, Xiaoran Zhang
Cancers. 2024-09-26
Journal Articles
- Targeted Therapy of Glioma Stem-like Cells and Tumor Non-stem Cells Using Cetuximab Conjugated Iron Oxide NanoparticlesKaluzova M, Bouras A, Machaidze R, Hadjipanayis CG, Oncotarget, 1/20/2015
- Radiosensitivity Enhancement of Radioresistant Glioblastoma by Epidermal Growth Factor Receptor Antibody-conjugated Iron-oxide NanoparticlesBouras A, Kaluzova M, Hadjipanayis CG, J Neurooncol, 1/1/2015
- Human Brat Ortholog TRIM3 Is a Tumor Suppressor and Regulates Asymmetric Cell Division in GlioblastomaChen G, Anand M, Kong J, Tucker-Burden C, Rong Y, Rahman F, Moreno CS, Van Meir EG, Hadjipanayis CG, Brat DJ, Cancer Res, 1/15/2014
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Books/Book Chapters
Abstracts/Posters
- Targeted Therapy of Glioma Stem Cells and Tumor Non-stem Cells Using Cetuximab-conjugated Iron-oxide NanoparticlesKaluzova M, Platt S, Bouras A, Kent M, Machaidze R, Hadjipanayis CG, Fourth Quadrennial Meeting of the World Federation of Neuro-oncology, San Francisco, CA, 1/24/2013
- Targeted Therapy of Glioma Stem Cells and Tumor Non-stem Cells Using Cetuximab-conjugated Iron-oxide NanoparticlesKaluzova M, Platt S, Bouras A, Kent M, Machaidze R, Hadjipanayis CG, Neurooncology, 1/1/2013
- Endoscopic Endonasal Resection of Clival ChordomasOrmond RD, Wise S, Oyesiku N, Patel A, Hadjipanayis CG, 23rd Annual North American Skull Base Society Meeting, Journal of Neurological Surgery-Part B Skull Base, Miami, FL, 1/1/2013
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Lectures
- Fluorescence-Guided Surgery of Malignant GliomaMadurai Neurosurgical Academy, Chennai, India - 1/28/2015
- Endoscopic Endonasal Resection of Clival ChordomaMadurai Neurosurgical Academy, Chennai, India - 1/28/2015
- Endoscopic Endonasal Approach to Pituitary TumorsMadurai Neurosurgical Academy, Chennai, India - 1/28/2015
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Other
- Constantinos G Hadjipanayis MD PhD Appointed Chair of the Department of Neurosurgery at Mount Sinai Beth Israel
http://www.mountsinai.org/about-us/newsroom/press-releases/constantinos-g-hadjipanayis-mdphd-appointed-chair-of-the-department-of-neurosurgery-at-mount-sinai-beth-israel-
1/1/2015 - Photo Essay: One Couple's Brain Tumor Journey by the American Association of Neurological Surgeons (AANS)
http://aansneurosurgeon.org/features/photo-essay-one-couples-brain-tumor-journey/
1/1/2015 - Course Manual, Congress of Neurological Surgeons Oral Board Review Course
Chicago - 1/8/2014 - Join now to see all
Press Mentions
- Synaptive Medical Présente Des Fonctionnalités Clefs De Sa Technologie De Microscopie Chirurgicale Robotique Modus V™ Lors Du CNS 2019October 15th, 2019
- Synaptive Medical Presents Key Features of Its Modus V™ Robotic Surgical Microscopy Technology at the 2019 CNS Annual MeetingOctober 15th, 2019
- FDA Approves Gliolan; Helps Patients with Glioblastoma Brain TumorsJuly 27th, 2017
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Professional Memberships
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