ColinASieffMD
Pediatric Hematology & Oncology • Boston, MAAssociate Professor, Pediatrics, Children's Hospital, Harvard Medical School
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Office
300 Longwood Ave
Boston, MA 02115Phone+1 617-258-5228Fax+1 617-258-6768
Education & Training
University of the WitwatersrandClass of 1968
Certifications & Licensure
MA State Medical License 1990 - 2023
Awards, Honors, & Recognition
- Elected Member The American Society for Clinical Investigation, 1988
Clinical Trials
- Safety and Efficacy Trial of Danazol in Patients With Fanconi Anemia or Dyskeratosis Congenita Start of enrollment: 2009 Nov 01
- Pilot Phase I/II Study of Amino Acid Leucine in Treatment of Patients With Transfusion-Dependent Diamond Blackfan Anemia Start of enrollment: 2013 Jun 01
Publications & Presentations
PubMed
- 5 citationsA Grammastola spatulata mechanotoxin-4 (GsMTx4)-sensitive cation channel mediates increased cation permeability in human hereditary spherocytosis of multiple genetic e...David H. Vandorpe, Boris E. Shmukler, Yann Ilboudo, Swati S. Bhasin, Beena E Thomas
Haematologica. 2021-06-10 - 15 citationsL-leucine improves anemia and growth in patients with transfusion-dependent Diamond-Blackfan anemia: Results from a multicenter pilot phase I/II study from the Diamond...Adrianna Vlachos, Evangelia Atsidaftos, Mohammad Lutfi Lababidi, Ellen Muir, Zora R. Rogers
Pediatric Blood & Cancer. 2020-12-01 - 21 citationsTGF-β signaling underlies hematopoietic dysfunction and bone marrow failure in Shwachman-Diamond syndromeCailin E. Joyce, Assieh Saadatpour, Melisa Ruiz-Gutierrez, Özge Vargel Bölükbaşı, Lan Jiang
The Journal of Clinical Investigation. 2019-09-03
Journal Articles
- The Phenotypic Spectrum of Germline YARS2 Variants: From Isolated Sideroblastic Anemia to Mitochondrial Myopathy, Lactic Acidosis and Sideroblastic Anemia 2Matthew M Heeney, Gregory A Hale, David P Steensma, Mark D Fleming, Colin A Sieff, Lee M Hilliard, Sylvia S Bottomley, Janet L Kwiatkowski, Haematologica
Other
- Regulation of erythropoiesisSieff CA
http://www.uptodate.com/contents/regulation-of-erythropoiesis
UpToDate, Wolters Kluwer Health - 2013-04-05 - Recombinant hematopoietic growth factors in inherited bone marrow failure syndromesSieff CA
http://www.uptodate.com/contents/recombinant-hematopoietic-growth-factors-in-inherited-bone-marrow-f
UpToDate, Wolters Kluwer Health - 2012-06-22 - Introduction to recombinant hematopoietic growth factorsSieff CA
http://www.uptodate.com/contents/introduction-to-recombinant-hematopoietic-growth-factors
UpToDate, Wolters Kluwer Health - 2012-04-24 - Join now to see all
Grant Support
- Developmental Biology Of Human HematopoiesisNational Center For Research Resources2004
- Genetic Heterogeneity And Protein Function In DBANational Heart, Lung, And Blood Institute2001–2003
- Correction Of RPS 19 Defects In Diamond Blackfan AnemiaNational Heart, Lung, And Blood Institute2000–2002
- Transplant Biology, Gene Transfer, And Stem Cell SourcesNational Heart, Lung, And Blood Institute1995–1998
- Sources And Actions Of GM-CSF And Multi-CsfNational Cancer Institute1994–1995
- The Sources And Actions Of Human GM-CSF And Multi-CsfNational Cancer Institute1991–1993
- Human Immunodeficiency Virus And HematopoiesisNational Institute Of Diabetes And Digestive And Kidney Diseases1989–1993
- Sources And Actions Of Human GM-CSF And Multi-CsfNational Cancer Institute1992
- Sources And Actions Of Human Gmcsf And Multi-CsfNational Cancer Institute1987–1989
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