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200 W Arbor DrSan Diego, CA 92103
Phone+1 800-926-8273
Fax+1 888-539-8781
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Summary
- I am a physician-scientist whose lab studies chromatin and epigenetic in neurodevelopment and lysosome function in neurodegeneration. We employ an array of omics methods and functional characterization in genetic mouse models and other systems. Clinically I am neuropathologist currently serving as Director of Ophthalmic Pathology.
Education & Training
Washington University/B-JH/SLCH ConsortiumFellowship, Neuropathology, 2015 - 2017- Washington University/B-JH/SLCH ConsortiumResidency, Pathology-Anatomic and Clinical, 2013 - 2016
University of Michigan Medical SchoolClass of 2013- Washington University/B-JH/SLCH ConsortiumResidency, Pathology-Anatomic and Clinical
Certifications & Licensure
CA State Medical License 2020 - 2026
MO State Medical License 2017 - 2021
American Board of Pathology Pathology - Anatomic- American Board of Pathology Neuropathology
Publications & Presentations
PubMed
- The Hao-Fountain syndrome protein USP7 regulates neuronal connectivity in the brain via a novel p53-independent ubiquitin signaling pathway.Hao Chen, Cole J Ferguson, Dylan C Mitchell, Isabel Risch, Amanda Titus
Cell Reports. 2025-02-25 - 5 citationsThe anaphase-promoting complex controls a ubiquitination-phosphoprotein axis in chromatin during neurodevelopment.Leya Ledvin, Brandon M Gassaway, Jonathan Tawil, Olivia Urso, Donald Pizzo
Developmental Cell. 2023-12-04 - Ectopic Fibrous Dysplasia Presenting As a Well-Circumscribed Orbital Mass.Tonya C Lee, Nicole J Topilow, Michelle A Ting, Melanie Estrella, Catherine Y Liu
Ophthalmic Plastic and Reconstructive Surgery. 2022-10-28
Grant Support
- Regulation of phase separation in neuronal heterochromatinUNIVERSITY OF CALIFORNIA, SAN DIEGO2024–2029
- Recognition and Ubiqutination of neurodevelopmental chromatin regulatorsUNIVERSITY OF CALIFORNIA, SAN DIEGO2024–2026
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