ClaudioGarciaBrunsteinMDPhD(He/Him)

Hematology • Cleveland, OH

Hematologic Oncology

Cleveland Clinic Foundation, Cleveland, OH

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Office
10201 Carnegie Ave
CA-60
Cleveland, OH 44195

Education & Training

University of MinnesotaFellowship, Hematology and Medical Oncology, 1998 - 2002
Federal University of Rio Grande do Sul School of MedicineClass of 1990

Certifications & Licensure

OH State Medical License 2022 - 2026
MN State Medical License 2002 - 2022
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Hematology

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

Chemotherapy and Total-Body Irradiation Followed by Donor Umbilical Cord Blood Transplant, Cyclosporine, and Mycophenolate Mofetil in Treating Patients With Hematologic Cancer Start of enrollment: 2001 Apr 01
Completed
Not Applicable
Non-Myeloablative Conditioning for Unrelated Donor Umbilical Cord Blood Transplant Start of enrollment: 2005 Jun 01
Completed
Phase 2
Myeloablative Umbilical Cord Blood Transplantation in Hematological Diseases Start of enrollment: 2005 Jul 28
Completed
Phase 2
Combination Chemotherapy and Total-Body Irradiation Before Donor Umbilical Cord Blood Transplant in Treating Patients With Advanced Hematologic Cancer, Metastatic Breast Cancer, or Kidney Cancer Start of enrollment: 2000 Jun 01
Completed
Phase 1, Phase 2
Umbilical Cord Blood T-Regulatory Cell Infusion Followed by Donor Umbilical Cord Blood Transplant in Treating Patients With High-Risk Leukemia or Other Hematologic Diseases Start of enrollment: 2007 May 01
Terminated
Phase 1
T-Regulatory Cell Infusion Post Umbilical Cord Blood Transplant in Patients With Advanced Hematologic Cancer Start of enrollment: 2007 Jul 23
Completed
Phase 1
Donor Umbilical Cord Blood Transplant After Fludarabine Phosphate, Cyclophosphamide, and Total-Body Irradiation in Treating Patients With High-Risk Hematologic Cancer Start of enrollment: 2010 Mar 01
Terminated
Phase 1, Phase 2
T-Regulatory Cell and CD3 Depleted Double Umbilical Cord Blood Transplantation in Hematologic Malignancies Start of enrollment: 2014 Jan 01
Withdrawn
Phase 1, Phase 2
Infusion of Cell Populations From Unlicensed Umbilical Cord Blood Units Start of enrollment: 2011 Oct 20
Recruiting
Not Applicable
Double Cord Versus Haploidentical (BMT CTN 1101) Start of enrollment: 2012 Jun 01
Completed
Phase 3
Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases Start of enrollment: 2016 Dec 01
Recruiting
Not Applicable
Treg Cells for AGVHD in Non-myeloablative UCB Transplant Start of enrollment: 2016 Jun 01
Withdrawn
Phase 2
Hematopoietic Stem Cell Transplant for High Risk Hemoglobinopathies Start of enrollment: 2014 Sep 02
Recruiting
Not Applicable
UCB Transplant for Hematological Diseases Using a Non Myeloablative Prep Start of enrollment: 2017 May 15
Active, not recruiting
Phase 2
Adoptive TReg Cell for Suppression of aGVHD After UCB HSCT for Heme Malignancies Start of enrollment: 2017 Feb 16
Terminated
Phase 2
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Publications & Presentations

PubMed

1 citations
Minimal Residual Disease Status in Multiple Myeloma 1 Year After Autologous Hematopoietic Cell Transplantation and Lenalidomide Maintenance Are Associated With Long-Te...
Marcelo C Pasquini, Paul K Wallace, Brent Logan, Manmeet Kaur, Joseph D Tario
Journal of Clinical Oncology. 2024-08-10
Harvest Quality, Nucleated Cell Dose and Clinical Outcomes in Bone Marrow Transplantation: A Retrospective Study.
Theodros Mamo, Darin Sumstad, Todd E DeFor, Qing Cao, Margaret L MacMillan
Transplantation and Cellular Therapy. 2023-10-01
3 citations
Tacrolimus/methotrexate vs tacrolimus/reduced-dose methotrexate/mycophenolate for graft-versus-host disease prevention.
Betty K Hamilton, Lisa A Rybicki, Hong Li, Taylor Lucas, Donna Corrigan
Blood Advances. 2023-08-22

Journal Articles

Diffuse Alveolar Hemorrhage Is Most Often Fatal and Is Affected by Graft Source, Conditioning Regiment Toxicity, and Engraftment Kinetics
Erhan H Dincer, Erica D Warlick, Margaret L MacMillan, Patrick Arndt, Daniel J Weisdorf, Nelli Bejanyan, Claudio G Brunstein, Celalettin Ustun, Aleksandr Lazaryan, Ver..., Haematologica

Abstracts/Posters

Mgta-456, an Aryl Hydrocarbon Receptor (AHR) Antagonist Based Expansion of CD34+ Hematopoietic Stem Cells (HSC), Permits Selection of Better HLA Matched Cord Blood Uni...
Claudio G. Brunstein, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Outcomes of Chronic Graft-Versus-Host Disease (cGVHD) Following Matched Sibling Donor (MSD) Versus Umbilical Cord Blood Transplant (UCBT)
Claudio G. Brunstein, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
Myeloablative Conditioning Is Preferred for Allogeneic Transplantation of Acute Myeloid Leukemia and Myelodysplastic Syndromes with Low/Intermediate but Not High Disea...
Claudio G. Brunstein, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Romiplostim Improves Platelet Recovery after UCB Transplant
Claudio G. Brunstein, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
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Lectures

Facilitating Resolution of Life-Threatening Acute Graft-Versus-Host Disease By Supplementation of Human Chorionic Gonadotropin and Epidermal Growth Factor (Pregnyl): A...
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018
Validation of Minnesota Acute Gvhd Risk Score and Identification of New Factors Associated with Initial Response to Steroids: Not All Gvhd Is Created Equal
2018 ASH Annual Meeting - San Diego, CA - 12/1/2018

Press Mentions

University of Minnesota Opens First-Ever U.S. Clinical Trial of Engineered iPSC-Derived Cell Therapy for Blood CancerOctober 23rd, 2019
First-Ever US Clinical Trial of Engineered iPSC-Derived Cell Therapy for Blood CancerOctober 21st, 2019
Half-Matched Transplants Widen Pool of Donors for Leukemia and LymphomaJuly 8th, 2011