Clare J Twist MD

Pediatric Hematology & Oncology•Buffalo, NY

Pediatric Solid Tumor Oncology

Clinical Professor and Fellowship Program Director, Jacobs School of Medicine and Biomedical Sciences at University at Buffalo; Professor, Roswell Park Comprehensive Cancer Center; Director of Pediatric Experimental Therapeutics, Roswell Park Comprehensive Cancer Center

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Elm and Carlton StBuffalo, NY 14263
Phone+1 716-845-2300
Fax+1 716-845-8003

Education & Training

Boston Children’s Hospital/Boston Medical CenterFellowship, Pediatric Hematology/Oncology, 1990 - 1993
McGaw Medical Center of Northwestern UniversityResidency, Pediatrics, 1988 - 1990
McGaw Medical Center of Northwestern UniversityInternship, Pediatrics, 1987 - 1988
Albany Medical CollegeClass of 1987

Certifications & Licensure

CA State Medical License 1999 - Present
NY State Medical License 2016 - 2026
IL State Medical License 1987 - 1990
American Board of Pediatrics Pediatric Hematology-Oncology

Awards, Honors, & Recognition

Outstanding Resident Teacher Award Children's Memorial Hospital, 1990

Clinical Trials

N2004-04: Fenretinide LXS in Treating Patients With Recurrent, Refractory, or Persistent Neuroblastoma Start of enrollment: 2005 Dec 01
Completed
Phase 1
Combination Chemotherapy and Surgery With or Without Isotretinoin in Treating Young Patients With Neuroblastoma Start of enrollment: 2007 Oct 08
Completed
Phase 3
N2004-03: Intravenous Fenretinide in Treating Young Patients With Recurrent or Resistant Neuroblastoma Start of enrollment: 2006 Dec 01
Completed
Phase 1
N2007-02:Bevacizumab,Cyclophosphamide,& Zoledronic Acid in Patients W/ Recurrent or Refractory High-Risk Neuroblastoma Start of enrollment: 2009 Dec 01
Completed
Phase 1
N2007-03: Vorinostat and 131-I MIBG in Treating Patients With Resistant or Relapsed Neuroblastoma Start of enrollment: 2010 Mar 01
Completed
Phase 1
Vorinostat and Isotretinoin in Treating Patients With High-Risk Refractory or Recurrent Neuroblastoma Start of enrollment: 2010 Dec 01
Completed
Phase 1
Lenalidomide and Dinutuximab With or Without Isotretinoin in Treating Younger Patients With Refractory or Recurrent Neuroblastoma Start of enrollment: 2013 Feb 04
ACTIVE_NOT_RECRUITING
PHASE1
N2012-01: Phase 1 Study of Difluoromethylornithine (DFMO) and Celecoxib With Cyclophosphamide/Topotecan Start of enrollment: 2014 Jan 16
COMPLETED
PHASE1
Irinotecan Hydrochloride, Temozolomide, and Dinutuximab With or Without Eflornithine in Treating Patients With Relapsed or Refractory Neuroblastoma Start of enrollment: 2019 Jul 08
ACTIVE_NOT_RECRUITING
PHASE2
A Pilot Study of SurVaxM in Children Progressive or Relapsed Medulloblastoma, High Grade Glioma, Ependymoma and Newly Diagnosed Diffuse Intrinsic Pontine Glioma Start of enrollment: 2022 Jul 01
RECRUITING
PHASE1
Roles: Study Chair, Contact
Bosutinib in Pediatric Patients With Newly Diagnosed Chronic Phase or Resistant/Intolerant Ph + Chronic Myeloid Leukemia Start of enrollment: 2020 Apr 06
ACTIVE_NOT_RECRUITING
PHASE1, PHASE2
Roles: Contact
A Study of TAK-755 in Participants With Congenital Thrombotic Thrombocytopenic Purpura Start of enrollment: 2021 Apr 14
Recruiting
Phase 3
Roles: Principal Investigator
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Publications & Presentations

PubMed

Evaluation of Image-Defined Risk Factor (IDRF) Assessment in Patients With Intermediate-risk Neuroblastoma: A Report From the Children's Oncology Group Study ANBL0531.
Erin G Brown, E Stanton Adkins, Peter Mattei, Fredric A Hoffer, Sandra L Wootton-Gorges
Journal of Pediatric Surgery. 2025-01-01
1 citations
Outcomes of patients with intermediate-risk neuroblastoma presenting with motor deficits relating to intraspinal tumor extension: A report from the Children's Oncology...
Julie Voeller, Howard M Katzenstein, Arlene Naranjo, Sheena C Tenney, Lulu Chen
Pediatric Blood & Cancer. 2025-01-01
Long-term follow-up of patients with intermediate-risk neuroblastoma treated with response- and biology-based therapy: A report from the Children's Oncology Group stud...
Erin K Barr, Arlene Naranjo, Clare J Twist, Sheena C Tenney, Mary Lou Schmidt
Pediatric Blood & Cancer. 2024-08-01

Press Mentions

Can Roswell Park’s Promising Brain Cancer Vaccine Work for Children and Young Adults?October 30th, 2024
Roswell Park-Developed Immunotherapy Now Part of Nationwide Study in Kids with Brain CancerJune 7th, 2022