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Christopher Yasenchak, MD, Oncology, Eugene, OR

ChristopherAndrewYasenchakMD

Oncology Eugene, OR

Hematologic Oncology

Willamette Valley Cancer Institute

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  • Office

    520 Country Club Pkwy
    Eugene, OR 97401
    Phone+1 541-683-5001
    Fax+1 541-683-1422

Summary

  • I am a lymphoma specialist, clinical researcher, and immunotherapy leader committed to bridging academic research with real-world oncology care, particularly for elderly and infirm patients. As CAR-T/Bispecifics Medical Director at Willamette Valley Cancer Institute, I lead a multidisciplinary team managing complex lymphoma cases, ensuring the safe and effective integration of CAR-T and bispecific antibody therapies into community-based practice.

    A major focus of my work is improving treatment options for elderly and frail patients, who often face unique challenges in lymphoma care, including limited tolerance for intensive therapies. As a Principal Investigator within the US Oncology Research network, I lead clinical trials focused on novel therapies for Classical Hodgkin Lymphoma (CHL) and other lymphomas, with a specific emphasis on tailoring treatments for elderly and high-risk populations.

    Additionally, as a Lymphoma Executive Committee Member at the Sarah Cannon Research Institute, I collaborate with global experts to translate the latest research into practical, community-based applications—helping expand access to innovative treatments beyond major academic centers.

    Key areas of focus:
    • Leadership in CAR-T and bispecific antibody therapies in community settings
    • Principal investigator in clinical trials for elderly and infirm patients with lymphoma
    • Advancing novel therapies for Classical Hodgkin Lymphoma in high-risk populations
    • Multidisciplinary care and real-world application of immunotherapies
    • Bridging academic research with practical applications in community-based oncology

    Over the past decade, my research efforts have resulted in numerous peer-reviewed publications, conference presentations, and collaborations with leading lymphoma experts. I am committed to expanding access to novel, less toxic therapies for elderly patients who might not tolerate traditional treatments, ensuring that innovative breakthroughs reach those who need them

Education & Training

  • Mayo Clinic College of Medicine and Science (Rochester)
    Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Hematology and Medical Oncology, 2003 - 2006
  • Johns Hopkins University
    Johns Hopkins UniversityFellowship, Allergy and Immunology, 2002 - 2003
  • Mayo Clinic College of Medicine and Science (Rochester)
    Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 1999 - 2002
  • Pennsylvania State University College of Medicine
    Pennsylvania State University College of MedicineClass of 1999

Certifications & Licensure

  • OR State Medical License
    OR State Medical License 2006 - 2025
  • WA State Medical License
    WA State Medical License 2006 - 2015
  • MN State Medical License
    MN State Medical License 2000 - 2010
  • Hematology
    American Board of Internal Medicine Hematology
  • Medical Oncology
    American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

  • Meaningful Use Stage 1 Certification Centers for Medicare & Medicaid Services, 2012
  • Portland Monthly Magazine Castle Connolly, 2011

Clinical Trials

Publications & Presentations

PubMed

Journal Articles

  • Results of a Phase 2 Placebo-Controlled Randomized Discontinuation Trial of Cabozantinib in Patients with Non–Small-Cell Lung Carcinoma  
    Beth A Hellerstedt, Nicholas J Vogelzang, Harriet M Kluger, Christopher A Yasenchak, Michael S Gordon, Primo Lara, Clinical Lung Cancer
  • An Open‐Label Phase 2 Trial of Entospletinib in Indolent Non‐Hodgkin Lymphoma and Mantle Cell Lymphoma  
    Jeff P Sharman, David J Andorsky, Christopher A Yasenchak, Kathryn S Kolibaba, British Journal of Haematology

Abstracts/Posters

  • Long-Term Proteasome Inhibitor (PI) Therapy in Community Patients (Pts) with Newly Diagnosed Multiple Myeloma (NDMM) Transitioning from Bortezomib (Btz)-Based to Ixazo...
    Christopher A. Yasenchak, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

Lectures

  • Brentuximab Vedotin in Front-Line Therapy of Hodgkin Lymphoma (HL) and CD30-Expressing Peripheral T-Cell Lymphoma (PTCL) in Adults Age 60 and Above 
    61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019

Authored Content

  • Results of a Phase 2 Placebo-Controlled Randomized Discontinuation Trial of Cabozantinib in Patients with Non–Small-Cell Lung CarcinomaOctober 2018

Press Mentions

  • US Oncology Research Announces Schedule of Presentations at the 2019 American Society of Hematology Annual Meeting and Exposition
    US Oncology Research Announces Schedule of Presentations at the 2019 American Society of Hematology Annual Meeting and ExpositionDecember 5th, 2019
  • Frontline Brentuximab Vedotin Generates 76% Complete Remission Rate in DLBCL
    Frontline Brentuximab Vedotin Generates 76% Complete Remission Rate in DLBCLDecember 22nd, 2015
  • More Treatment-Guiding Interim PET-CT Scans Needed in Advanced Stage Hodgkin Lymphoma
    More Treatment-Guiding Interim PET-CT Scans Needed in Advanced Stage Hodgkin LymphomaDecember 4th, 2023

Committees

  • PI/SubI, Phase I Research Program. US Oncology Research. 2013 - Present
  • PI/SubI, Hematology Research Program. US Oncology Research. 2008 - Present

Research History

  • Associate Chair, Hematology Research Program. US Oncology Research2013 - Present

Professional Memberships