ChristopherLlewellynKarpMD
Internal Medicine • Seattle, WAInfectious Disease
Director, Discovery & Translational Sciences
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Office
1432 Elliott Ave W
Seattle, WA 98119Phone+1 206-747-2343
Summary
- Chris Karp, M.D. is the Director of Global Health Discovery & Translational Sciences at the Bill & Melinda Gates Foundation, a team whose mission is to catalyze innovation for the discovery and translation of transformative solutions to global health and development inequity.
Prior to the foundation, he was on the faculty of the departments of Medicine and Molecular Microbiology & Immunology at Johns Hopkins University School of Medicine and founded the division of Molecular Immunology at Cincinnati Children's Hospital Research Foundation, where he was Esiason/Bell Professor of Pediatrics. His academic scientific career focused on defining the mechanisms underlying the regulation and dysregulation of inflammatory responses in infectious, allergic, and genetic diseases, with a focus on diseases of children.
Education & Training
MedStar Health/Georgetown University HospitalResidency, Internal Medicine, 1987 - 1989
Brown UniversityResidency, Internal Medicine, 1986 - 1987
University of North Carolina at Chapel Hill School of MedicineClass of 1986
Certifications & Licensure
OH State Medical License 2001 - 2026- American Board of Internal Medicine Internal Medicine
Awards, Honors, & Recognition
- Distinguished Fellow American Association of Immunologists, 2024
- Elected Member Association of American Physicians, 2010
- Elected Member The American Society for Clinical Investigation, 2003
Publications & Presentations
PubMed
- 74 citationsThermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.Daniel A Giles, Maria E Moreno-Fernandez, Traci E Stankiewicz, Simon Graspeuntner, Monica Cappelletti
Nature Medicine. 2017-07-01 - 193 citationsIL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice.Isaac T.W. Harley, Traci E. Stankiewicz, Daniel A. Giles, Samir Softic, Leah M. Flick
Hepatology. 2014-05-01 - 652 citationsInterleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitisMasako Murai, Olga Turovskaya, Gisen Kim, Rajat Madan, Christopher L. Karp
Nature Immunology. 2009-11-01
Press Mentions
Data Behind Vaccine Hesitancy and Latest Updates on Vaccines in the Pipeline—2019 Annual Conference on Vaccinology Research, April 3–5, 2019December 10th, 2019- Guilt by Intimate Association: What Makes an Allergen an Allergen?May 1st, 2010
Grant Support
- Regulation Of TLR Signaling And Innate Immunity By RP105National Institute Of Allergy And Infectious Diseases2010–2011
- Allergenicity Resulting From Functional Mimicry Of The TLR ComplexNational Institute Of Allergy And Infectious Diseases2010–2011
- Immunobiology Of Ifrd1, A Gene Modifying CF Lung DiseaseNational Heart, Lung, And Blood Institute2010–2011
- Modulation Of Tissue Inflammation By Rp105/Tlr4National Institute Of Arthritis And Musculoskeletal And Skin Diseases2010
- Novel Immune-Based Therapy For Leishmaniasis And TuberculosisNational Institute Of Allergy And Infectious Diseases2009
- Immunobiology Of Ifrd1, A Gene Modifying CF Lung DiseaseNational Heart, Lung, And Blood Institute2009
- Regulation Of TLR Signaling And Innate Immunity By RP105National Institute Of Allergy And Infectious Diseases2007–2009
- Modulation Of Tissue Inflammation By Rp105/Tlr4National Institute Of Arthritis And Musculoskeletal And Skin Diseases2006–2009
- Lipid Mediators And Dysregulated Inflammation In CFNational Heart, Lung, And Blood Institute2005–2009
- Role Of Regulatory T Cells In Leishmania Major InfectionNational Institute Of Allergy And Infectious Diseases2005–2008
- Regulation Of Toll-Like Receptor Signaling By RP105National Institute Of Allergy And Infectious Diseases2005–2006
- Novel Lipid -Based Therapies For Cystic FibrosisNational Heart, Lung, And Blood Institute2004
- Ebola Virus: Immunopathogenesis And TherapyNational Institute Of Allergy And Infectious Diseases2002–2003
- IFN Beta And Immunoregualtion In Multiple SclerosisNational Institute Of Neurological Disorders And Stroke2000–2003
- Hepatitis C: Ifn-Alpha, IL-12 And ImmunoregulationNational Institute Of Diabetes And Digestive And Kidney Diseases2000–2003
- Conference On Macrophage Activation And DeactivationNational Institute Of Allergy And Infectious Diseases2001
- Immunosuppression In Measles--The Role Of IL 12 And CD46National Institute Of Allergy And Infectious Diseases2000–2001
- IFN Beta And Immunoregualtion In Multiple SclerosisNational Institute Of Neurological Disorders And Stroke2000
- Hepatitis C--Ifn-Alpha, IL-12 And ImmunoregulationNational Institute Of Diabetes And Digestive And Kidney Diseases1999
- Immunosuppression In Measles--The Role Of IL 12 And CD46National Institute Of Allergy And Infectious Diseases1997–1999
- Molecular Mechanisms Of HIV Induced ImmunosuppressionNational Institute Of Dental &Craniofacial Research1996–1998
- Measles--T Cells, Cytokine Profiles And ImmunoregulationNational Institute Of Allergy And Infectious Diseases1994–1996
- NIH Intramural Nrsa Institutional Training ProgramNational Institute Of Allergy And Infectious Diseases1990–1991
- NIH Intramural Nrsa Institutional Training ProgramNational Institute Of Allergy And Infectious Diseases1989
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