Christopher L Holley MD PhD

Cardiology•Saint Louis, MO

Heart Failure & Transplantation, Non-Invasive Cardiology

Associate Professor of Medicine, Duke University

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1 Barnes Jewish Hospital PlzSaint Louis, MO 63110
Phone+1 314-362-1291
Fax+1 314-362-4278

Summary

Dr. Christopher Holley is a cardiologist in Durham, NC and is affiliated with Duke University Hospital. He received his medical degree from Duke University School of Medicine and has been in practice 13 years. He specializes in heart failure, transplantation, and LVAD management. Additionally, he is an NIH-funded basic scientist with an active research program investigating the role of non-coding RNAs and RNA modifications in cardiovascular health and disease.

Education & Training

Washington University/B-JH/SLCH ConsortiumFellowship, Cardiovascular Disease, 2006 - 2012
Washington University/B-JH/SLCH ConsortiumResidency, Internal Medicine, 2004 - 2006
Duke University School of MedicineClass of 2004
Duke University Graduate School of Arts and SciencesPhD, Pharmacology, 2004
Duke UniversityBS, Biology, 1995

Certifications & Licensure

MO State Medical License 2006 - 2026
NC State Medical License 2015 - 2026
American Board of Internal Medicine Advanced Heart Failure and Transplant Cardiology
American Board of Internal Medicine Cardiovascular Disease

Awards, Honors, & Recognition

Strong Start Physician-Scientist Award Duke University School of Medicine, 2017
Health Fellow Award Duke University School of Medicine, 2016
Junior Faculty Development Award Duke Heart Center Leadership Council, 2016
Northwestern Cardiovascular Young Investigators’ Forum Finalist 2014
Burton E. Sobel Award for Cardiovascular Research 2010
Rising Star Award for Cardiovascular Research 2007
Knowlton Incentive for Excellence Award 2006
Phi Beta Kappa 1994
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Publications & Presentations

PubMed

1 citations
Single-cell mA profiling in the mouse brain uncovers cell type-specific RNA methylomes and age-dependent differential methylation.
Matthew Tegowski, Anna K Prater, Christopher L Holley, Kate D Meyer
Nature Neuroscience. 2024-12-01
4 citations
Programmable protein expression using a genetically encoded mA sensor.
Bahjat F Marayati, Matthew G Thompson, Christopher L Holley, Stacy M Horner, Kate D Meyer
Nature Biotechnology. 2024-09-01
4 citations
Early Outcomes in Patients With LVAD Undergoing Heart Transplant via Use of the SherpaPak Cardiac Transport System.
Joseph B Lerman, Chetan B Patel, Sarah Casalinova, Alina Nicoara, Christopher L Holley
Circulation. Heart Failure. 2024-05-01

Books/Book Chapters

Washington Manual Cardiology Subspecialty Consult
Chapter: Evaluation of Acute Chest Pain
Holley CLEditors: Cuculich PS, Kates AM.Lippencott Williams & Wilkins, Philadelphia, PAEdition 3rd,2014
Washington Manual Cardiology Subspecialty Consult
Chapter: Approach to Syncope
Holley CL, Cooper DH, and Nordlicht SMEditors: Cuculich PS, Kates AM.Lippencott Williams & Wilkins, Philadelphia, PAEdition 3rd,2014
The Washington Manual of Echocardiography
Chapter: Quantification of Left Ventricular Systolic and Diastolic Function
Holley CLEditors: Rasalingam R, Makan M, Perez J.Lippencott Williams & Wilkins, Philadelphia, PA2012
The Washington Manual of Echocardiography
Chapter: Cardiomyopathies
Holley CLEditors: Rasalingam R, Makan M, Perez J.Lippencott Williams & Wilkins, Philadelphia, PA2012
An Introduction to Small Non-coding RNAs: miRNA and snoRNA
Holley CL, Topkara VK2011
Handbook of Clinical Nutrition and Aging
Chapter: Chronic Heart Failure
Holley C, Rich MWEditors: Bales CW, Ritchie CS.Humana Press, New York, NYEdition Seco,2009
Washington Manual Cardiology Subspecialty Consult
Chapter: Evaluation of Chest Pain
Holley CL, Subherwal SEditors: Cuculich PS, Kates AM.Lippencott Williams & Wilkins, Philadelphia, PAEdition 2nd,2008
Washington Manual Cardiology Subspecialty Consult
Chapter: Syncope
Holley CLEditors: Cuculich PS, Kates AM.Lippencott Williams & Wilkins, Philadelphia, PAEdition 2nd,2008
Washington Manual of Critical Care
Chapter: Acute Decompensated Heart Failure
Holley CL, Ewald GAEditors: Kollef MH, Bedient TJ, Isakow W, Witt CA.Lippencott Williams & Wilkins, Philadelphia, PA2008
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Grant Support

Mechanisms by which Small Nucleolar RNAs Exacerbate AtherosclerosisDUKE UNIVERSITY2022–2026
The Role of RNA Modifications in Heart FailureDUKE UNIVERSITY2019–2025
The Role of RNA Modifications in Heart FailureDUKE UNIVERSITY2019–2025