ChristopherScottBryantMD

PubMed

• 80 citations
  Chk1 Inhibition as a novel therapeutic strategy for treating triple-negative breast and ovarian cancers
  Christopher J. Bryant, Rebecca Rawlinson, Andrew J Massey
  BMC Cancer. 2014-08-07
• 31 citations
  A population-based analysis of 788 cases of yolk sac tumors: A comparison of males and females.
  Jay P. Shah, Sanjeev Kumar, Christopher S. Bryant, Rouba Ali-Fehmi, John M. Malone
  International Journal of Cancer. 2008-12-01
• 71 citations
  Ritonavir blocks AKT signaling, activates apoptosis and inhibits migration and invasion in ovarian cancer cells.
  Sanjeev Kumar, Christopher S. Bryant, Sreedhar Chamala, Aamer Qazi, Shelly Seward
  Molecular Cancer. 2009-04-22

Journal Articles

• Smooth muscle neoplasms of the vulva masquerading as Bartholin gland duct cysts  
  Levy RA, Winham WM, Bryant CS, Quick CM, Proc (Bayl Univ Med Cent), 1/1/2014
• EZH2 blockade by RNA interference inhibits growth of ovarian cancer by facilitating re-expression of p21(waf1/cip1) and by inhibiting mutant p53  
  Seward S, Semaan A, Qazi AM, Gruzdyn OV, Chamala S, Bryant CS, Kumar S, Cameron D, Sethi S, Ali-Fehmi R, Morris R, Bouwman DL, Munkarah AR, Weaver DW, Gruber SA, Batch..., Cancer Lett, 1/9/2013
• MicroRNA-01 Inhibits growth of epithelial ovarian cancer by reliving chromatin-mediated transcriptional repression of p21waf1/cip1  
  Seman A, Qazi, A, Seward S, Shreedar C, Bryant CS, Kumar S, Morris RT, Steffes C, Bowman D, Munkarah AR, Weaver D, Gruber S, Batchu RB, Pharm Res, 1/1/2011
• Intraoperative Detection of Nodal Metastasis in Early Stage Cervical Cancer: A Survey of the Practice Patterns of SGO Members  
  Garg G, Shah JP, Toy EP, Field JB, Bryant CS, Liu JR, Morris RT, Gynecol Oncol, 1/1/2011
• Ovarian and uterine carcinosarcoma: A comparative analysis of prognostic variables and survival outcomes  
  Garg G, Shah JP, Kumar S, Bryant CS, Munkarah A, Morris RT, Int J Gyn Cancer, 1/1/2010
• Life threatening clostridial sepsis in a post-menopausal patient with degenerating uterine leiomyoma  
  Bryant CS, Perry L, Shah JP, Kumar S, Deppe G, Case Report Med, 1/1/2010
• Surgery for endometrial cancer complicated by postoperative chylous ascites: A case report  
  Bryant CS, Kumar S, Shah JP, Munkarah AR, Morris RT, Deppe G, Archive of Oncology, 1/1/2010
• Sacral metastases in an endometrial cancer patient after treatment with sequential chemo-radiotherapy: A case report  
  Bryant CS, Shah JP, Kumar S, Munkarah AR, Morris RT, Deppe G, Archive of Oncology, 1/1/2010
• Validation of Tumor Size as Staging Variable in the Revised FIGO Stage 1 Leiomyosarcoma: A Population Based Study  
  Garg G, Shah JP, Liu JR, Bryant CS, Kumar S, Munkarah A, Morris RT, Int J Gynecol Cancer, 1/1/2010
• Stage IA vs IB endometrial stromal sarcoma: does the new staging system predict survival?  
  Garg G, Shah JP, Toy EP, Bryant CS, Kumar S, Morris RT, Gynecol Oncol, 1/1/2010
• Feasibility of extension of platinum-free interval with weekly bolus topotecan and subsequent platinum retreatment outcomes in recurrent ovarian cancer  
  Bryant CS, Kumar S, Spannuth W, Shah JP, Munkarah AR, Deppe G, Alvarez RD, Morris RT, Arch Gynecol Obstet, 1/1/2010
• Clinical trials and progress with paclitaxel in ovarian cancer  
  Kumar S, Haider M, Shah JP, Garg G, Bryant CS, Munkarah A, Int J Wom Health, 1/1/2010
• Analysis of the expression of human tumor antigens in ovarian cancer tissues  
  Ali-Fehmi R, Chatterjee M, Ionan A, Levin NK, Arabi H, Bandyopadhyay S, Shah JP, Bryant CS, Hewitt SM, O'Rand MG, Alekseev OM, Morris, R, Munkarah A, Abrams J, Tainsky MA, Cancer Biomark, 1/1/2010
• Reduction of hypoxia-induced angiogenesis in ovarian cancer cells by inhibition of HIF-1alpha gene expression  
  Bryant CS, Munkarah AR, Kumar S, Batchu RB, Shah JP, Berman J, Morris RT, Jiang ZL Saed GM, Arch Gynecol Obstet, 1/1/2010
• Sulforaphane Induces Cell Cycle Arrest by Protecting RB-E2F-1 Complex in Epithelial Ovarian Cancer Cells  
  Bryant CS, Kumar S, Chamala S, Shah J, Pal J, Haider M, Seward S, Qazi AM, Morris R, Semaan A, Potti RB, Shammas MA, Steffes C, Weaver DW, Prasad M, Batchu RB, Mol Cancer, 1/1/2010
• Racial disparities in survival among patients with germ cell tumors of the ovary-United States  
  Bryant CS, Kumar S, Shah JP, Mahdi H, Ali-Fehmi R, Munkarah AR, Deppe G, Morris RT, Gynecol Oncol, 1/1/2009
• Impact of Sulforaphane, alone or in combination with paclitaxel on cell growth, genome wide expression profile, and genomic integrity, in Barrett's adenocarcinoma cells  
  Qazi A, Stark B, Batchu RB, Chamala S, Bryant CS, Steffes CP, Beer DG, Weaver DW, Prasad M, Shammas MA, J Surg Res, 1/1/2009
• Impact of microsatellite instability (MSI) on survival in high grade endometrial carcinoma  
  Arabi H, Guan H, Kumar S, Cote M, Bandyopadhyay S, Bryant C, Shah J, Abdul-Karim FW, Munkarah AR, Ali-Fehmi R, Gynecol Oncol, 1/1/2009
• Ritonavir blocks AKT signaling, activates apoptosis and inhibits migration and invasion in ovarian cancer cells  
  Kumar S, Bryant CS, Chamala S, Qazi A, Seward S, Pal J, Steffes C, Weaver D, Morris RT, Malone J JR, Shammas M, Prasad M, Batchu RB, Mol Cancer, 1/1/2009
• Carboplatin and paclitaxel adjuvant chemotherapy in primitive neuroectodermal tumors of the uterine corpus  
  Shah JP, Jelsema J, Bryant CS, Ali-Fehmi R, Malone JM, Am J Obstet Gynecol, 1/1/2009
• A successful pregnancy following fertility sparing surgery for peritoneal psammocarincoma: A Case Report  
  Shah JP, Bryant CS, Kumar S, Ali-Fehmi R, Morris RT, J Reprod Med, 1/1/2009
• Prognostic significance of keratinization in squamous cell cancer of the uterine cervix: a population based study  
  Kumar S, Shah JP, Bryant CS, Imudia AN, Ali-Fehmi R, Malone JM Jr, Morris RT, Arch Gynecol Obstet, 1/1/2009
• Lymphadenectomy and ovarian preservation in low grade endometrial stromal sarcoma  
  Shah JP, Kumar S, Bryant CS, Ali-Fehmi R, Malone JM, Morris RT, Obstet Gynecol, 1/1/2008
• A population based analysis of 788 cases of Yolk Sac Tumors: A comparison of males and females  
  Shah JP, Kumar S, Bryant CS, Ali-Fehmi R, Malone JM Jr., Deppe G, Morris RT, Int J Cancer, 1/1/2008
• Topotecan weekly bolus chemotherapy for relapsed platinum-sensitive ovarian and peritoneal cancers  
  Morris R, Alverez RD, Andrews S, Malone JM Jr., Bryant C, Heilbrun L, Smith D, Schimp S, Munkarah A, Gynecol Oncol, 1/1/2008
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Books/Book Chapters

• High Risk Pregnancy Management Options 
  Chapter: Malignant disease in pregnancy. 
  Munkarah AR, Bryant CS, Schimp VLEditors: James DK, Steer PJ, Weiner CP, Gonik B.W.B. Saunders Company, LondonEdition 3rd,

Abstracts/Posters

• Lentiviral delivery of EzH2 shRNA inhibits tumor growth of epithelial ovarian cancer.
  Batchu RB, Semaan A, Seward SM, Qazi A, Chamala S, Bryant CS, Steffes C, Kumar S, Shammas MA, Weaver DW, American Society of Gene & Cell Therapy (ASGCT) 13th Annual Meeting, Washington, DC, 1/17/2010
• MiR-101 inhibits cell growth and impedes invasiveness in ovarian cancer cells by targeted epigenetic silencing of EzH2.
  Batchu RB, Semaan A, Seward SM, Qazi A, Chamala S, Bryant CS, Steffes C, Kumar K, Shammas MA, Weaver DW, ASCO Annual Meeting, Chicago, IL, 1/4/2010
• Hospital-based study of uterine serous carcinoma survival in Caucasian and African-American women.
  Al-Wahab Z, Ali R, Shah JP, Bryant CS, Cote M, Morris R, Munkarah R, Gynecol Oncol; 41st Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2010
• Effect Of Sulforaphane On Barrett's Adenocarcinoma Cells In Vitro And In Vivo: Mechanism Of Growth Inhibition And Enhancement Of Action Of Antiproliferative Agents.
  Qazi A, Pal J, Maitah M, Fulciniti M, Pelluru D, Nanjappa P, Batchu RB, Prasad M, Bryant CS, Rajput S, Anderson KC, Gryaznov S, Beer DG, Weaver D, Munshi NC, Goyal RK,..., Digestive disease week (DDW), New Orleans, LA, 1/1/2010
• Ritonavir Mediated Induction of Apoptosis in Pancreatic Cancer: Involvement of RB/E2F-1 and AKT Pathways.
  Bryant CS, Prasad M, Kumar S, Qazi A, Chamalas, Pal J, Shah J, Seward S, Shammas MA, Batchu RB, 40th Anniversary meeting of the American Pancreatic Association and Japanese Pancreas Society, Honolulu, HI, 1/4/2009
• Impact of [18F]fluro-2-deoxyglucose PET imaging on therapeutic decision making in patients with recurrent ovarian carcinoma.
  Ballon-Hennings HG, Bryant CS, Vay A, Shah JP, Seward SM, Deppe G, Malone JM, Morris RT, Gynecol Oncol; 40th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2009
• Molecular markers predicting recurrence in type I endometrial carcinoma.
  Seward SM, Heyek K, Shah JP, Bryant CS, Vay A, Morris RT, Munkarah AR, Ali-Fehmi R, Gynecol Oncol; 40th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2009
• Radiation-associated endometrial cancer: A population-based case-control study.
  Kumar S, Shah JP, Bryant CS, Vay A, Seward S, Mahdi H, Ali-Fehmi R, Morris RT, Malone JM, Gynecol Oncol; 40th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2009
• Comparison of survival disparity between Whites and African-Americans with malignant germ cell tumors of the ovary.
  Bryant CS, Kumar S, Shah JP, Vay A, Seward S, Ali-Fehmi R, Deppe G, Malone JM, Morris RT, Gynecol Oncol; 40th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2009
• Ritonavir potentiates the antiproliferative effect of paclitaxel and inhibits cell invasion and migration in ovarian cancer.
  Kumar S, Pal J, Bryant CS, Chamala S, Qazi A, Steffes CP, Shammas M, Weaver DW, Malone JM, Morris RT, Prasad M, Batchu RB, Gynecol Oncol; 40th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2009
• Role of EZH2 in ovarian carcinogenesis.
  Ali-Fehmi, Munkarah A, Bryant CS, Shah JP, Kumar S, Malone JM, Morris RT, Sood AK, Gynecol Oncol; 40th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2009
• Ritonavir Mediated Induction of Apoptosis in Pancreatic Cancer: Involvement of RB/E2F-1 and AKT Pathways.
  Bryant CS, Prasad M, Kumar S, Qazi A, Chamala s, Pal J, Shah J, Seward S, Shammas MA, Batchu RB, Gynecol Oncol; 40th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2009
• Ovarian cancer associated with endometriosis carries an improved prognosis.
  Ali-Fehmi R, Shah JP, Bryant CS, Arabi H, Bandyopadhyay S, Al-Wahab A, Malone JM, Schimp VL, Munkarah AR, Morris RT, Gynecol Oncol; 39th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2008
• Papillary serous carcinoma of the cervix, two case reports.
  Al-Wahab A, Bryant CS, Solomon LA, Shah JP, Vay A, Malone J Jr, Morris RT, AAGL 37th Global Congress, Las Vegas, NV, 1/1/2008
• A modified dose schedule for intraperitoneal chemotherapy in gynecologic cancers.
  Al-Wahab A, Solomon LA, Bryant CS, Vay A, Malone J Jr, Shah JP, Morris RT, AAGL 37th Global Congress, Las Vegas, NV, 1/1/2008
• Second neoplasms in survivors of endometrial cancer: Impact of radiation therapy.
  Kumar S, Bryant CS, Shah JP, Ruterbusch JJ, Cote ML, Vay A, Solomon LA, Ali-Fehmi R, Morris RT, Malone JM Jr., J Clin Oncol; 44th Annual meeting for the American Society of Clinical Oncology, 1/1/2008
• Ritonavir exhibits antineoplastic activity in ovarian cancer cell lines by cell cycle arrest and induction of apoptosis.
  Kumar S, Bryant CS, Qazi A, Morris RT, Steffes C, Prasad M, Weaver D, Shammas A, Batchu RB, Gynecol Oncol; 39th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2008
• An analysis of 788 cases of yolk sac tumors in males and females: A population-based study.
  Shah JP, Kumar S, Bryant CS, Vay A, Solomon L, Malone JM, Ali-Fehmi R, Schimp VL, Morris RT, Gynecol Oncol; 39th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2008
• The prevalence and prognostic impact of lymph node metastasis in malignant germ cell tumors of the ovary.
  Kumar S, Shah JP, Bryant CS, Akers SN, Vay A, Ali-Fehmi R, Malone JM Jr, Morris RT, Schimp VL, Gynecol Oncol; 39th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2008
• Sulforaphane, an antioxidant derived from broccoli, induces cell cycle arrest and apoptosis in epithelial ovarian cancer cells.
  Bryant CS, Kumar S, Qazi A, Ali-Fehmi R, Morris RT, Steffes C, Prasad M, Weaver D, Shammas M, Batchu RB, Gynecol Oncol; 39th Annual Meeting for the Society of Gynecologic Oncologists, 1/1/2008
• Impact of Microsatellite Instability (MSI) on Survival in High Grade Endometrial Carcinoma.
  Arabi MH, Cote M, Bryant CS, Shah JP, Munkarah AR, Ali-Fehmi R, Mod Pathol, 1/1/2007
• Endometrial carcinoma (EC) in women 35 years of age or younger.
  Ali-Fehmi R, Cote M, Arabi MH, Bryant CS, Shah JP, Mughrabi L, Schimp VL, Sauder K, Abdul-Karim F, Munkarah AR, Lab Invest, 1/1/2007
• Should Intraoperative Frozen Section Diagnosis Be Used to Determine Surgical Staging for Patients with Endometrial Carcinoma.
  Ali-Fehmi R, Arabi MH, Morris RT, Schimp VL, Bryant CS, Shah JP, Munkarah AR, Sakr W, Mod Pathol, 1/1/2007
• Endometrial carcinoma (EC) in women 35 years of age or younger.
  Ali-Fehmi A, Cote M, Arabi MH, Bryant CS, Shah JP, Mughrabi L, Schimp VL, Sauder K, Abdul-Karim F, Munkarah AR, Mod Pathol, 1/1/2007
• Expression of COX-2, VEGF, Ki-67, and p53 in Advanced Stage, High-Grade Serous Ovarian Carcinoma with Prolonged Survival
  Arabi MH, Shah JP, Bryant CS, Morris RT, Schimp V, Mughrabi M, Munkarah AR, Ali-Fehmi R, Mod Pathol, 1/1/2007
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Lectures

• "Ovarian Cancer Awareness" 
  Jonesboro, AR - 1/1/2012
• "Breast and Ovarian Cancer Syndromes" 
  Peitz Cancer Support House, Baxter County, Mountain Home, AR - 1/1/2012
• "Cervical Cancer Screening and Prevention" 
  Peitz Cancer Support House, Baxter County, Mountain Home, AR - 1/1/2012
• "da Vinci Surgical Systems: Minimally Invasive Surgery" 
  Rotary Club, Baxter County, Mountain Home, AR - 1/1/2011
• "Gynecologic Malignancies A Minimally Invasive Surgical Approach" 
  Schliemann Women's Center, Baxter County, Mountain Home, AR - 1/1/2011
• "Gynecologic Malignancies" 
  Schliemann Women's Center, Baxter County, Mountain Home, AR - 1/1/2011
• Tumor Markers and Screening in Gynecologic Oncology Patients. 
  Orlando, FL - 1/1/2010
• Grand Rounds: "Prognosticators for fetal acidemia in term pregnancies of laboring patients with suspected chorioamnionitis." 
  Wayne State University, Department of Obstetrics and Gynecology, Detroit, MI - 1/1/2009
• Grand Rounds: "Impact of 18fluro-2-deoxy-glucose positron emission tomography (FDG-PET) imaging on therapeutic decision making in patients with recurrent ovarian carci... 
  Wayne State University, Department of Obstetrics and Gynecology, Detroit, MI - 1/1/2009
• Grand Rounds: "Inhibition of Angiogenesis during Hypoxia by Knocking-Out the Expression of HIF-1a in Ovarian Cancer Cells." 
  Wayne State University, Department of Obstetrics and Gynecology, Detroit, MI - 1/1/2009
• Grand Rounds: "Treatment of Gynecologic Cancers." 
  Wayne State University, Department of Urology, Detroit, MI - 1/1/2008
• Grand Rounds: "Cytoreductive Surgery and The Impact of Residual Disease on the Outcome of Epithelial Ovarian Cancer Patients." 
  Wayne State University, Department of Obstetrics and Gynecology, Detroit, MI - 1/1/2008
• Ritonavir exhibits antineoplastic activity in ovarian cancer cell lines by cell cycle arrest and induction of apoptosis. 
  1/1/2006
• Grand Rounds: "Gestational Trophoblastic Disease." 
  Oakwood Hospital and Medical Center, Dearborn, MI - 1/1/2006
• Grand Rounds: "Acute postoperative hemorrhage: Diagnosis and management." 
  John D. Dingell VA Medical Center, Detroit, MI - 1/1/2006
• Cervical Cancer. 
  Wayne State University, Detroit, MI - 1/1/2006
• Vulvar/Vaginal cancer. 
  Wayne State University, Department of Obstetrics and Gynecology, Detroit, MI - 1/1/2006
• Intraoperative & Perioperative Complications and Management. 
  Wayne State University, Department of Obstetrics and Gynecology, Detroit, MI - 1/1/2006
• Ovarian cancer. 
  Wayne State University, Detroit, MI - 1/1/2005
• Epithelial Ovarian Cancer. 
  Wayne State University, Department of Obstetrics and Gynecology, Detroit, MI - 1/1/2005
• Uterine cancer. 
  Wayne State University, Detroit, MI - 1/1/2005
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