ChristineElizabethMarxMD

Psychiatry • Durham, NC

"Professor of Psychiatry and Behavioral Sciences Faculty Network Member of the Duke Institute for Brain Sciences Vice Chair for Faculty in Psychiatry and Behavioral Sciences Chief, Division of Translational Neuroscience"

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Office
508 Fulton St
Durham Va Medical Center, Mhsl 116a
Durham, NC 27705
Phone+1 919-286-0411

Fax+1 919-286-6811

Summary

Dr. Christine Marx, MD is a board certified psychiatrist in Durham, North Carolina. She is currently licensed to practice medicine in North Carolina. She is affiliated with Durham Veterans Affairs Medical Center and is a "Professor of Psychiatry and Behavioral Sciences Faculty Network Member of the Duke Institute for Brain Sciences Vice Chair for Faculty in Psychiatry and Behavioral Sciences Chief at Division of Translational Neuroscience".

Education & Training

University of North Carolina HospitalsFellowship, Consultation-Liaison Psychiatry, 1997 - 1998
Duke University HospitalResidency, Psychiatry, 1994 - 1997
Duke University School of MedicineClass of 1992

Certifications & Licensure

NC State Medical License 1998 - 2025
American Board of Psychiatry and Neurology Psychiatry

Clinical Trials

Cooperative Studies Program #563 - Prazosin and Combat Trauma PTSD Start of enrollment: 2010 Jan 06
Completed
Phase 3
Schizophrenia and PTSD Project: Health, Interventions, and Risk/Resilience Evaluation(SAPPHIRE Study) Start of enrollment: 2007 Mar 01
Active, not recruiting
Targeting Cognition in PTSD: Pregnenolone Augmentation of SSRIs Start of enrollment: 2006 Apr 01
Completed
Not Applicable
Pilot Study of Pregnenolone Augmentation Targeting Cognitive Symptoms in Persistently Symptomatic Patients With Schizophrenia Start of enrollment: 2005 Jun 01
Completed
Not Applicable
Omega-3 Fatty Acids and Post Traumatic Stress Disorder (PTSD) Start of enrollment: 2008 Sep 22
Completed
Not Applicable
Pregnenolone for Cognitive and Negative Symptoms in Schizophrenia Start of enrollment: 2009 Dec 01
Completed
Phase 2
Neuroactive Steroids and Traumatic Brain Injury (TBI) in OEF/OIF Veterans Start of enrollment: 2013 Oct 01
Completed
Phase 2
Ganaxolone in Posttraumatic Stress Disorder (PTSD) Start of enrollment: 2011 Apr 01
Completed
Phase 2
Complementary Neurosteroid Intervention in Gulf War Illnesses (GWVI) Start of enrollment: 2013 Oct 01
Completed
Phase 2
Neurosteroids for PTSD in Veterans Start of enrollment: 2019 May 01
Recruiting
Phase 2
Allopregnanolone in Chronic Complex Traumatic Brain Injury Start of enrollment: 2024 Sep 01
Not yet recruiting
Phase 2
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Publications & Presentations

PubMed

119 citations
Olanzapine and clozapine increase the GABAergic neuroactive steroid allopregnanolone in rodents.
Christine E. Marx, Margaret J. VanDoren, Gary E. Duncan, Jeffrey A. Lieberman, A. Leslie Morrow
Neuropsychopharmacology. 2003-01-01
66 citations
Clozapine markedly elevates pregnenolone in rat hippocampus, cerebral cortex, and serum: candidate mechanism for superior efficacy?
Christine E. Marx, Lawrence J. Shampine, Gary E. Duncan, Margaret J. VanDoren, A. Chistina Grobin
Pharmacology, Biochemistry, and Behavior. 2006-08-01
12 citations
Effect of Pregnenolone vs Placebo on Self-reported Chronic Low Back Pain Among US Military Veterans: A Randomized Clinical Trial.
Jennifer C. Naylor, Jason D. Kilts, Lawrence J. Shampine, Gillian Parke, H. Ryan Wagner
JAMA Network Open. 2020-03-02

Press Mentions

Berlin & Brandenburg: Network Offers Help with Canceled OperationsNovember 23rd, 2020

Grant Support

Neuroactive Steroids And TBI In OEF/OIF VeteransVeterans Affairs2011
Proof-Of-Concept InvestigationsNational Institute On Drug Abuse2010–2011
Neurosteroids And SchizophreniaNational Institute Of Mental Health2001–2005