ChristinaLaukaitisMDPhD, FACP, FACMG(She/Her)

PubMed

• 75 citations
  Repeat associated mechanisms of genome evolution and function revealed by the Mus caroli and Mus pahari genomes.
  David Thybert, Maša Roller, Fabio C. P. Navarro, Ian T. Fiddes, Ian Streeter
  Genome Research. 2018-03-21
• 27 citations
  Human rDNA copy number is unstable in metastatic breast cancers.
  Virginia Valori, Katalin Tus, Christina M. Laukaitis, David T. Harris, Lauren LeBeau
  Epigenetics. 2020-02-01
• 36 citations
  DFMO: Targeted risk reduction therapy for colorectal neoplasia
  Christina M. Laukaitis, Eugene W. Gerner
  Best Practice & Research. Clinical Gastroenterology. 2011-08-01

Journal Articles

• An Unusual BRCA Mutation Distribution in a High Risk Cancer Genetics Clinic  
  Nelson-Moseke, A.C*, Jeter, J.M., Cui, A., Roe, D.J., Chambers, S.K., and Laukaitis, C.M., Familial Cancer, 1/1/2013
• Genetics for the General Internist  
  Laukaitis, C.M., American Journal of Medicine, 1/1/2012
• Congenic strain analysis reveals genes that are rapidly evolving components of a prezygotic isolation mediating incipient reinforcement  
  Karn, R.C., Mauss, C. and Laukaitis, C.M., PLOS One, 1/1/2012
• DFMO: Targeted Risk Reduction Therapy  
  Laukaitis, C.M. and Gerner, E.W., Best Practice and Research: Clinical Gastroenterology, 1/1/2011
• A Novel Defensive Mechanism against Acetaminophen Toxicity in the Mouse Lateral Nasal Gland: Role of CYP2A5-mediated regulation of testosterone homeostasis and salivar...  
  Zhou, X., Wei, Y., Xie, F., Laukaitis, C.M., Karn, R.C., Kluetzman, K., Gu, J., Zhang, Q-Y., Roberts, D.W., and Ding, X., Molecular Toxicology, 1/1/2011
• Reinforcement selection acting on the European house mouse hybrid zone  
  Voslajerova Bimova, B., Macholan, M., Baird, S.E.B., Munclinger, P., Laukaitis, C.M., Karn, R.C., Luzynski, K., Tucker, P., Pialek, J., Molecular Ecology, 1/1/2011
• The mechanism of expansion and the volatility it created in three pheromone gene clusters in the mouse genome  
  Karn, R.C. and Laukaitis, C.M., Genome Biology and Evolution, 1/1/2009
• Evolution of the secretoglobins: A genomic and proteomic view  
  Laukaitis, C.M. and Karn, R.C., Biological Journal of the Linnean Society, 1/1/2005
• Diverse spatial, temporal, and sexual expression of recently duplicated androgen-binding protein genes in Mus musculus  
  Laukaitis, C.M., Dlouhy, S.R., Emes, R.D., Ponting, C.P., and Karn, R.C., BMC Evolutionary Biology, 1/1/2005
• The mouse salivary androgen-binding protein (ABP) gene cluster on chromosome 7: Characterization and evolutionary relationships  
  Laukaitis, C.M., Dlouhy, S.R., and Karn, R.C., Mammalian Genome, 1/1/2003
• Differential dynamics of 5 integrin, paxillin, and -actinin during formation and disassembly of adhesions in migrating cells  
  Laukaitis, C.M., Donais, K., Webb, D.J., and Horwitz, A.F., Journal of Cell Biology, 1/1/2001
• Salivary androgen-binding protein (ABP) mediates sexual isolation in Mus Musculus.  
  Laukaitis, C. M., Critser, E. S. and Karn, R. C, Evolution
• Chemoprevention in patients with genetic risk of colorectal cancers.  
  Laukaitis, C.M., Erdman, S.H. and Gerner, E.W, Colorectal Cancer
• A candidate Mus muculus subspecies discrimination system involving a V1R gene with different alleles fixed in M. m. domesticus and M. m. musculus.  
  Karn, R.C., Young, J.M., and Laukaitis, C.M, PLOS One
• Rapid bursts of Abp gene duplication occurred independently in diverse mammals.  
  Laukaitis, C.M., Heger, A., Blakley, T.D., Munclinger, P., Ponting, C.P., and Karn, R.C, BMC Evolutionary Biology
• Evolution of the secretoglobins: A genomic and proteomic view.  
  Laukaitis, C.M. and Karn, R.C, Biological Journal of the Linnean Society
• Rapid duplication and sequence diversification within the rodent androgen-binding protein (ABP) gene cluster.  
  Emes, R.D., Riley, M.C., Laukaitis, C.M., Goodstadt, L., Karn, R.C., and Ponting, C.P, Genome Research
• Differential dynamics of 5 integrin, paxillin, and -actinin during formation and disassembly of adhesions in migrating cells.  
  Laukaitis, C. M., Donais, K., Webb, D. J., and Horwitz, A. F, Journal of Cell Biology
• Visualizing cell migration in situ.  
  Knight, B., Laukaitis, C. M., Akhtar, N., Hotchin, N. A., Edlund, M. and Horwitz, A. R, Current Biology
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Books/Book Chapters

• Fundamentals of Cancer Prevention 
  Chapter: Breast cancer prevention 
  Thompson, P.A., Stopeck, A. and Laukaitis, C.M.Editors: D. Alberts and L. Hess.Springer-Verlag, Berlin, GermanyEdition 3rd,2013
• Recognition of subspecies status in the evolution of incipient reinforcement on the European house mouse hybrid zone 
  Chapter: Evolution of the House Mouse 
  Laukaitis, C.M., and Karn, R.C.Editors: M. Macholan et al..Cambridge University Press, Cambridge, UK2012
• Cellular Integration of Signalling Pathways in Plant Development. NATO ASI Series. Series H: Cell Biology 
  Chapter: Intercellular and intracellular trafficking: What we can learn from Geminivirus movement 
  Lazarowitz, S.G., Ward, B.M., Sanderfoot, A.A., and Laukaitis, C.M.Springer-Verlag, Berlin, Germany1997
• Cellular Integration of Signalling Pathways in Plant Development. 
  Chapter: Intercellular and intracellular trafficking: What we can learn from Geminivirus movement 
  Lazarowitz, S. G., Ward, B. M., Sanderfoot, A. A., and Laukaitis, C. MNATO ASI Series. Series H: Cell Biology, Vol. 104, Springer, Verlag, Berlin, Germany
• Evolution of the House Mouse. 
  Chapter: Recognition of subspecies status in the evolution of incipient reinforcement on the European house mouse hybrid zone 
  Laukaitis, C.M., and Karn, R.CEditors: M. Macholán et al.Cambridge University Press, Cambridge, UK
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Abstracts/Posters

• Frequent BRCA1/2 Mutations Found in Mexican & Mexican - American Women with Breast Cancer
  Chaudhury, A., Laukaitis, C.M., Mauss, C., Walsh, T., Casadei, S., Thompson, P., Lopez, AM, Daneri Navarro, A., King, M-C., American Association for Cancer Research (AACR) San Antonio Breast Cancer Symposium, San Antonio, TX, 12/1/2013
• QSOX1: A Desmoid Tumor Modifier Gene in FAP?
  Maher, K., Walton, S-J, Mauss, C., Clark, S., Laukaitis, C.M., American College of Physicians Arizona Chapter Scientific Meeting, Tucson, AZ, 11/1/2013
• University of Arizona Cancer Center High Risk Breast Cancer Genetics Clinic Perspective on Utilization of a Custom Next Generation Sequencing Panel
  Chaudhury, A., Mauss, C., Jeter, J.M., Laukaitis, C.M., American College of Physicians Arizona Chapter Scientific Meeting, Tucson, AZ, 11/1/2013
• Genomic evaluation of inherited predisposition to breast cancer among women of Mexican ancestry
  C.M. Laukaitis, A. Chaudhury, C. Mauss, T. Walsh, P. Thompson, A-M Lopez, A. Daneri Navarro, M-C King, American Society of Human Genetics Annual Meeting, Boston, MA, 10/1/2013
• Genomic Evaluation of Inherited Predisposition to Breast Cancer in Women from the University of Arizona Cancer Center High Risk Breast Cancer Genetics Clinic
  Chaudhury, A., Mauss, C., Jeter, J.M., Laukaitis, C.M., American Association for Cancer Research (AACR) Special Conference on Advances in Breast Cancer Research: Genetics, Biology, & Clinical Applications, San Diego, CA, 10/1/2013
• Seeking genes that predict desmoid formation in patients with familial adenomatous polyposis
  Laukaitis, C.M, Maher, K., Walton, S-J, Mauss, C., Clark, S., International Society for Inherited Gastrointestinal Tumors Semi-annual Meeting, Cairns, Australia, 8/1/2013
• Expression of Androgen-binding protein genes (Abp) in lacrimal glands and tear secretions
  Chung, A., Mauss, C., Karn, R.C., Laukaitis, C.M., American College of Medical Genetics, Annual Meeting, Phoenix, AZ, 3/1/2013
• Seeking genes that predict desmoid formation in patients with familial adenomatous polyposis
  Maher, K., Walton, S-J, Mauss, C., Clark, S., Laukaitis, C.M., American College of Medical Genetics Annual Meeting, Phoenix, AZ, 3/1/2013
• Understanding Genetic Polymorphisms and Susceptibility in High Risk Breast Cancer
  Chaudhury, A., Mauss, C., Jeter, J., Laukaitis, C.M., American College of Medical Genetics Annual Meeting, Phoenix, AZ, 3/1/2013
• Prevalence of Genetic Mutations in Mexican and Mexican-American Women with Breast Cancer
  Mauss, C., Thompson, P., Garcia, F., Lopez, AM, Laukaitis, C.M., American College of Medical Genetics Annual Meeting, Phoenix, AZ, 3/1/2013
• An Unusual BRCA Mutation Distribution in a High Risk Cancer Genetics Clinic
  Nelson-Moseke, A.C, Jeter, J.M., Cui, A., Roe, D.J., Chambers, S.K., and Laukaitis, C.M., American Society of Human Genetics, San Francisco, CA, 11/1/2012
• Identifying gene copy number variants associated with colorectal adenoma recurrence
  Laukaitis, C.M., Thompson, P., Martinez, M-E., and Gerner, E.W., Beyond the Genome: The human gene count, human evolution and disease genomics, Boston, MA, 10/1/2010
• A candidate subspecies discrimination system involving a vomeronasal receptor gene with different alleles fixed in M. m. domesticus and M. m. musculus
  Karn, R.C. and Laukaitis, C.M., Beyond the Genome: The human gene count, human evolution and disease genomics, Boston, MA, 10/1/2010
• Detecting Copy Number Variation in Candidate Genes for Colorectal Cancer Risk
  Laukaitis, C.M. and Thompson, P., NCI Translational Science Meeting, Vienna, VA, 11/1/2009
• Behavioral isolation in the house mouse hybrid zone
  Bimova, B., Macholan, M., Munclinger, P., Laukaitis, C.M., Karn, R. C., Tucker, P., Pialek, J., 11th International Conference on Rodent Biology "Rodens et Spatium"; 12th Congress of European Society for Evolutionary Biology, Myshkin, Russia (2005); Turin, Italy (2009), 7/1/2009
• The evolutionary history of a gene involved in adaptive evolution
  Karn R.C., Laukaitis C.M., Munclinger P., European Society for Evolutionary Biology 10th Congress, Krakow, Poland, 8/1/2005
• The test of behavioral isolation on the mouse hybrid zone: the comparison of behavioral and molecular cline
  Bimova, B, Macholan, M., Munclinger, P., Laukaitis, C.M., Karn, R.C., Pialek J., European Society for Evolutionary Biology 10th Congress, Krakow, Poland, 8/1/2005
• Diverse spatial, temporal, and sexual expression of recently duplicated androgen-binding protein genes in Mus musculus
  Laukaitis, C.M., Dlouhy, S.R., Emes, R.D., Ponting, C.P., and Karn, R.C., European Society for Evolutionary Biology 10th Congress, Krakow, Poland, 8/1/2005
• Where and when are Abp-like gene copies expressed?
  Laukaitis, C.M., Karn, R.C, American College of Physicians Annual Session, San Francisco, CA
• Does germline variation in the number of Glutathione S-transferase gene copies affect the risk of metachronous colorectal neoplasia?
  Laukaitis C.M. and Fuentes-Mauss, C, International Congress of Human Genetics, Montreal, CA
• Identifying gene copy number variants associated with colorectal adenoma recurrence.
  Laukaitis, C.M., Thompson, P., Martinez, M-E., and Gerner, E.W, Beyond the Genome: The human gene count, human evolution and disease genomics, Boston, MA
• Detecting Copy Number Variation in Candidate Genes for Colorectal Cancer Risk.
  Laukaitis, C. and Thompson, P, NCI Translational Science Meeting, Vienna, VA
• Behavioural isolation in the house mouse hybrid zone.
  Bímová, B., Macholán, M., Munclinger, P., Laukaitis, C.M., Karn, R.C., Baird, S.J.E., Piálek, J, 12th Congress of European Society for Evolutionary Biology, Turin, Italy
• Rapid bursts of Abp gene duplication in rodents and other mammals.
  Laukaitis, C.M. and Karn, R.C, Invited seminar, Masyryk University, Brno, CR
• Behavioral isolation in the house mouse hybrid zone.
  Bímová, B., Macholán, M., Munclinger, P., Laukaitis, C. M., Karn, R. C., Tucker, P., Piálek, J, 11th International Conference on Rodent Biology „Rodens et Spatium, Myshkin, Russia
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Lectures

• Selection shaped the evolution of mouse androgen-binding protein (ABP) function and promoted the duplication of Abp genes” 
  Plon, Germany - 5/1/2014
• Insensitivity to antigrowth signals 
  Oro Valley, AZ - 5/1/2014
• Inherited Predisposition to Breast Cancer in Mexican and Mexican American Women 
  4/1/2014
• Inherited cancer risk in patients from the UA High-risk Cancer Genetics Clinic 
  Tucson, AZ - 2/1/2014
• Cancer BASICS 
  Tucson, AZ - 6/1/2013
• Genetic Testing for the Primary Care Physician 
  Tucson, AZ - 4/1/2013
• Genetic Breast Cancer Syndromes: Cancer is Preventable, but Patients are Under-recognized 
  Tucson, AZ - 4/1/2013
• Colorectal Cancer 
  Flagstaff, AZ - 3/1/2013
• Desmoid Tumor Genetics 
  1/1/2013
• Genetic Testing; Promise and Reality 
  11/1/2012
• The evolutionary history of three mouse pheromone gene families 
  Brno, Czech Republic - 11/1/2012
• Clinical Cancer Genetics Research 
  10/1/2012
• Ovarian cancer screening and prevention 
  Tucson, AZ - 9/1/2012
• “Cancer Basics”, “Cancer Types and Treatments” and “Cancer Prevention” 
  Seattle, WA - 7/1/2012
• Cancer basics and prevention 
  Window Rock, AZ - 6/1/2012
• Clinical Trials of Cancer Prevention 
  Window Rock, AZ - 6/1/2012
• Cancer 101 
  Tucson, AZ - 3/1/2012
• Hereditary Cancer Syndromes, Maternal and Pediatric Considerations 
  Telluride, CO - 2/1/2012
• Identifying and caring for women at high risk of breast cancer 
  Polacca, AZ - 12/1/2011
• Evidence for cancer screening and prevention; Identification of the patient at high-risk for breast cancer 
  San Xavier, AZ - 8/1/2011
• Lynch syndrome and renal cancer: Not so rare in Native Arizona 
  Chinle, AZ - 5/1/2011
• Genetics for Pulmonologists 
  Tucson, AZ - 2/1/2011
• Care of the patient at high risk of cancer 
  Tucson, AZ - 12/1/2010
• Colon cancer in high-risk populations 
  Polacca, AZ - 12/1/2010
• Genetics for the General Internist 
  Tucson, AZ (2009-2010) - 9/1/2010
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