ChristianEdwardIsaacMD, MSc, FRCSC

PubMed

• 44 citations
  Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.
  Christian Isaac, Adam Wright, Arvydas Usas, Hongshuai Li, Ying Tang
  Journal of Orthopaedic Research. 2013-03-01
• 92 citations
  Biologic approaches to enhance rotator cuff healing after injury
  Christian Isaac, Burhan Gharaibeh, Michelle R. Witt, Vonda J. Wright, Johnny Huard
  Journal of Shoulder and Elbow Surgery. 2012-02-01
• 125 citations
  Loss of ATRX leads to chromosome cohesion and congression defects.
  Kieran Ritchie, Claudia Seah, Jana M. Moulin, Christian Isaac, Frederick A. Dick
  The Journal of Cell Biology. 2008-01-28

Journal Articles

• Loss of ATRX Leads to Chromosome Cohesion and Congression Defects  
  Ritchie, K., Seah, C., Moulin, J., Isaac, C., Dick, F., & Berube, N.G., The Journal of Cell Biology, 1/1/2018
• Management of soft-tissue sarcomas; treatment strategies, staging, and outcomes  
  Ramu, E., Houdek, M., Isaac, C., Dickie, C., Ferguson, P., & Wunder, J., SICOT-J, 1/1/2017
• Cell Synchronization of Mouse Embryonic Fibroblasts  
  Thwaites, Michael J., Coschi, Courtney H., Isaac, C., & Dick, F, Methods in Molecular Biology, 1/1/2016
• Dystrophin and Utrophin �Double Knockout� Dystrophic Mice Exhibit a Spectrum of Degenerative Musculoskeletal Abnormalities  
  Isaac, C., Wright, A., Usas, A., Li, H., Tang, Y., Mu, X., Greco, N., Dong, Q., Vo, N., Kang, J., Wang, B, & Huard, J., Journal of Orthopaedic Research, 1/1/2013
• Notch Signaling is Associated with ALDH Activity and An Aggressive Metastatic Phenotype in Murine Osteosarcoma Cells  
  Mu, X., Isaac, C., Greco, N., Huard, J., & Weiss, K., Frontiers in Oncology, 1/1/2013
• Biological Approaches to Enhance Rotator Cuff Healing After Injury  
  Isaac, C., Gharaibeh, B., Witt, M., Wright, V., & Huard, J., Journal of Shoulder and Elbow Surgery, 1/1/2012
• A G1 Checkpoint Mediated by the Retinoblastoma Protein That is Dispensable in Terminal Differentiation But Essential For Senescence  
  Talluri, S., Isaac, C.E., Ahmad, M., Henley, S.A., Francis, S.M., Martens, A.L., Bremner, R., & Dick, F.A., Molecular and Cellular Biology, 1/1/2010
• A Functional Connection Between pRB and Transforming Growth Factor Beta in Growth Inhibition and Mammary Gland Development  
  Francis, S.M., Bergsied, J., Isaac, C.E., Coschi, C.H., Martens, A.L., Hojilla, C.V., Chakrabarti, S., DiMattia, G.E., Khoka, R., Wang, J.Y.J., & Dick, F.A., Molecular and Cellular Biology, 1/1/2009
• The Retinoblastoma Protein Regulates Pericentric Heterochromatin  
  Isaac, C.E., Francis, S.M., Martens, A.L., Julian, L.M., Seifried, L.A., Erdmann, N., Binne, U.K., Harrington, L., Sicinski, P., Berube, N.G., Dyson, N.J., & Dick, F.A., Molecular and Cellular Biology, 1/1/2006
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Abstracts/Posters

• The Biological Significance of Tumor Growth During Preoperative Radiation
  Isaac C, Canadian Orthopedic Association Annual Meeting Ottawa, International Society of Limb Salvage, Japan, 1/1/2017

Lectures

• Bone Abnormalities and Impaired Bone Healing in Double Knockout Utrophin/Dystrophin Mice 
  San Francisco, CA - 1/1/2012