CharlesAStanleyMD

Pediatric Endocrinology • Philadelphia, PA

Professor Emeritus of Pediatrics, University Pennsylvania

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Office
3401 Civic Center Blvd
Childrens Hospital of Philadelphia Endocrinology
Philadelphia, PA 19104
Phone+1 215-590-3174

Fax+1 215-590-3053

Education & Training

Children's Hospital of PhiladelphiaResidency, Pediatrics, 1970 - 1975
University of Virginia School of MedicineClass of 1970

Certifications & Licensure

NJ State Medical License 1982 - Present
PA State Medical License 1972 - 2021
American Board of Pediatrics Pediatrics
American Board of Pediatrics Pediatric Endocrinology

Awards, Honors, & Recognition

Super Doctor SuperDoctors.com

Clinical Trials

Effect of Exendin (9-39) on Glucose Requirements to Maintain Euglycemia Start of enrollment: 2009 Aug 26
Terminated
Phase 1, Phase 2
Effect of Exendin-(9-39) on Fasting Adaptation and Protein Sensitivity Start of enrollment: 2009 May 01
Completed
Phase 1, Phase 2

Publications & Presentations

PubMed

106 citations
Hyperinsulinism/hyperammonemia syndrome in children with regulatory mutations in the inhibitory guanosine triphosphate-binding domain of glutamate dehydrogenase.
Courtney MacMullen, Jie Fang, Betty Y.L. Hsu, Andrea Kelly, Pascale de Lonlay-Debeney
The Journal of Clinical Endocrinology and Metabolism. 2001-04-01
135 citations
Molecular basis and characterization of the hyperinsulinism/hyperammonemia syndrome: predominance of mutations in exons 11 and 12 of the glutamate dehydrogenase gene. ...
Charles A. Stanley, Jie Fang, Karen Kutyna, Betty Y.L. Hsu, Jeffrey E. Ming
Diabetes. 2000-04-01
495 citations
Hyperinsulinism and hyperammonemia in infants with regulatory mutations of the glutamate dehydrogenase gene.
Charles A. Stanley, Yen K. Lieu, Betty Y.L. Hsu, Alberto Burlina, Cheryl R. Greenberg
The New England Journal of Medicine. 1998-05-07

Journal Articles

Congenital Hyperinsulinism in Infants with Turner Syndrome: Possible Association with Monosomy X and KDM6A Haploinsufficiency
Christopher E Gibson, Charles A Stanley, Tricia Bhatti, N Scott Adzick, Vaneeta Bamba, Hormone Research in Paediatrics

Lectures

KATP Channel Dysfunction in Beta-Cell Leads to Hypoglycemia in Beckwith-Wiedemann Syndrome
Philadelphia, PA - 6/15/2014

Press Mentions

Charities Spreading Overdose Medication Across Metro AtlantaApril 18th, 2023
CHOP Doctor Awarded the Congenital Hyperinsulinism International "Be My Sugar" Award for Medical ExcellenceNovember 20th, 2018

Grant Support

Islet Dysregulation In Infants With Congenital HyperinsulinismNational Institute Of Diabetes And Digestive And Kidney Diseases2009–2012
Pediatric Endocrine Fellowship Training In Diabetes ResearchNational Institute Of Diabetes And Digestive And Kidney Diseases2007–2011
Meso Scale Discovery Sector 6000 ImagerNational Center For Research Resources2010
Molecular Basis Of A New Form Of HyperinsulinismNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2010
Islet Dysregulation In InfantsNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2008
Ped Endocrine Career Development In Diabetes ResearchNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2007
International Medical Conference Of Congenital HyperinsulinismNational Institute Of Diabetes And Digestive And Kidney Diseases2006
Ped Endocrine Fellowship Training In Diabetes ResearchNational Institute Of Diabetes And Digestive And Kidney Diseases2004–2006
Treatment Options For Type 2 Diabetes In Adolescents And YouthNational Center For Research Resources2005
Islet Dysregulation In Infants With Congenital HyperinsulinismNational Center For Research Resources2005
Effective Management Of Pediatric Type 2 Diabetes Melli*National Institute Of Diabetes And Digestive And Kidney Diseases2004
Islet Dysregulation In Infants With Congenital HyperinsulinismNational Center For Research Resources2004
Effective Management Of Pediatric Type 2 Diabetes Melli*National Institute Of Diabetes And Digestive And Kidney Diseases2003
Ped Endocrine Fellowship Training In Diabetes ResearchNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2003
Ped Endocrine Career Development In Diabetes ResearchNational Institute Of Diabetes And Digestive And Kidney Diseases2002–2003
Islet Dysregulation In InfantsNational Institute Of Diabetes And Digestive And Kidney Diseases1999–2003
Molecular Basis Of A New Form Of HyperinsulinismNational Institute Of Diabetes And Digestive And Kidney Diseases1998–2003
Management Of Pediatric Type 2 Diabetes MellitusNational Institute Of Diabetes And Digestive And Kidney Diseases2001–2002
Islet Dysregulation In Congenital HyperinsulinismNational Center For Research Resources2000–2002
Regulation Of Insulin Secretion In Congenital HyperinsulinismNational Center For Research Resources1997–2000
Genetic Basis Of Congenital HyperinsulinismNational Center For Research Resources1994–2000
Acarbose--Postprandial Hypoglycemia In Children With Glycogen Storage DisordersNational Center For Research Resources1998–1999
Fuel Kinetics In Disorders Of Fasting HypoglycemiaNational Center For Research Resources1993–1999
Effect Of Acarbose On Hypoglycemia In Children With Glycogen Storage DisordersNational Center For Research Resources1997
Regulation Of Carnitine Transport In B-Oxidation DefectsNational Institute Of Diabetes And Digestive And Kidney Diseases1992–1996
Somatostatin Therapy In HyperinsulinismNational Center For Research Resources1991–1995
Riboflavin Therapy In MCAD DeficiencyNational Center For Research Resources1993–1994
Somatropin In Hypopituitary ChildrenNational Center For Research Resources1992
Humatrope And Low Dose Estrogen In Turner'S SyndromeNational Center For Research Resources1991–1992
Somatotropin In Hypopituitary ChildrenNational Center For Research Resources1990–1991
Mechanisms Of Primary And Secondary Carnitine DeficiencyNational Center For Research Resources1990–1991
Humatrope And Low Dose Estrogen In Turners SyndromeNational Center For Research Resources1990
Carnitine Treatment Of Secondary Carnitine DeficiencyNational Center For Research Resources1985–1989
Renal Studies In Type I Glycogen Storage DiseaseNational Center For Research Resources1988
Poorly Controlled Congenital Adrenal Hyperplasia/HumanNational Center For Research Resources1987–1988
MET Hgh Treatment For Growth Hormone Deficiency With Hypoglycemia Risk/HumanNational Center For Research Resources1987
Valproic Acid And Carnitine MetabolismNational Center For Research Resources1985–1986
Hepatic Fatty Acid Oxidation In Reye'S SyndromeNational Center For Research Resources1985–1986
Evaluation Of Hyperinsulinism In InfancyNational Center For Research Resources1985–1986