CharlesAlanSchifferMD

Oncology • Detroit, MI

Hematologic Oncology

Professor, Internal Medicine, Wayne State University School of Medicine

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Office
4100 John R St
Detroit, MI 48201
Phone+1 800-527-6266

Fax+1 313-576-8767

Education & Training

NYU Grossman School of MedicineResidency, Internal Medicine, 1968 - 1972
New York University School of MedicineClass of 1968

Certifications & Licensure

MI State Medical License 1997 - 2025
MD State Medical License 1975 - 1997
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Medical Oncology

Awards, Honors, & Recognition

America's Top Doctors Castle Connolly, 2002-2014
America's Top Doctors for Cancer Castle Connolly, 2005-2013
Fellow (FASCO) American Society of Clinical Oncologists, 2010
Super Doctor SuperDoctors.com
Whos Who in Medicine and Healthcare Marquis Whos Who
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Clinical Trials

Trial to Reduce Alloimmunization to Platelets (TRAP) Start of enrollment: 1989 Aug 01
Completed
Phase 3
S0020 Immunosuppressive Therapy in Treating Patients With Myelodysplastic Syndrome Start of enrollment: 2001 Aug 01
Completed
Phase 2
Imatinib Mesylate and 17-N-Allylamino-17-Demethoxygeldanamycin in Treating Patients With Chronic Myelogenous Leukemia Start of enrollment: 2003 Jun 01
Completed
Phase 1
Lenalidomide With or Without Epoetin Alfa in Treating Patients With Myelodysplastic Syndrome and Anemia Start of enrollment: 2009 Jan 29
Active, not recruiting
Phase 3
Dasatinib for Modulating Immune System After Autologous Stem Cell Transplants for Multiple Myeloma, Non-Hodgkin, or Hodgkin Lymphoma Start of enrollment: 2015 Feb 12
Terminated
Phase 1
Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic Malignancies Start of enrollment: 2012 May 01
Terminated
Phase 1
Cytarabine and Daunorubicin Hydrochloride or Idarubicin and Cytarabine With or Without Vorinostat in Treating Younger Patients With Previously Untreated Acute Myeloid Leukemia Start of enrollment: 2013 Feb 12
Completed
Phase 3
Ibrutinib in Treating Patients With Relapsed Hairy Cell Leukemia Start of enrollment: 2013 Apr 30
Active, not recruiting
Phase 2
Antigen-specific T Cell Therapy for Patients With Relapsed Refractory Multiple Myeloma Start of enrollment: 2020 Aug 17
Suspended
Phase 1, Phase 2
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Publications & Presentations

PubMed

Acute myeloid leukemia management and research in 2025.
Hagop M Kantarjian, Courtney D DiNardo, Tapan M Kadia, Naval G Daver, Jessica K Altman
CA. 2024-12-10
Project Confirm: Accelerated Drug Approvals for CML-Response.
Kendra L Sweet, Jorge E Cortes, Jane F Apperley, Mel Mann, Michael J Mauro
Clinical Cancer Research. 2024-01-05
Glasdigib fails to slay the hedgehog in pivotal AML trials.
Charles A Schiffer
Leukemia. 2023-12-01

Journal Articles

Promoting Apoptosis with Venetoclax — A Benefit for Older Patients with AML
Charles Schiffer, MD, The New England Journal of Medicine

Abstracts/Posters

Combined Treatment with Lenalidomide and Epoetin Alfa Leads to Durable Responses in Patients with Epo-Refractory, Lower Risk Non-Deletion 5q [Del(5q)] MDS: Final Resul...
Charles A. Schiffer, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
Patient-Reported Outcome Results from the U.S. Life after Stopping TKIs (LAST) Study in Patients with Chronic Myeloid Leukemia
Charles A. Schiffer, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
High Dependence on Medicare and Foundation Grant Assistance Among Patients with Hematologic Malignancies Receiving Novel Oral Therapeutics
Charles A. Schiffer, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019

Other

To What Extent Can Mathematical Modeling Inform the Design of Clinical Trials? The Example of Safe Dose Reduction of Tyrosine Kinase Inhibitors in Responding Patients ...
Charles Schiffer, MD, Haematologica
https://www.doximity.com/articles/4681238f-f736-4d40-8426-f4cf919fa658
UpToDate, Wolters Kluwer Health - 2013-03-20
To What Extent Can Mathematical Modeling Inform the Design of Clinical Trials? The Example of Safe Dose Reduction of Tyrosine Kinase Inhibitors in Responding Patients ...
Charles Schiffer, MD, Haematologica
https://www.doximity.com/articles/4681238f-f736-4d40-8426-f4cf919fa658
UpToDate, Wolters Kluwer Health - 2013-01-03
To What Extent Can Mathematical Modeling Inform the Design of Clinical Trials? The Example of Safe Dose Reduction of Tyrosine Kinase Inhibitors in Responding Patients ...
Charles Schiffer, MD, Haematologica
https://www.doximity.com/articles/4681238f-f736-4d40-8426-f4cf919fa658
UpToDate, Wolters Kluwer Health - 2012-02-14
To What Extent Can Mathematical Modeling Inform the Design of Clinical Trials? The Example of Safe Dose Reduction of Tyrosine Kinase Inhibitors in Responding Patients ...
Charles Schiffer, MD, Haematologica
https://www.doximity.com/articles/4681238f-f736-4d40-8426-f4cf919fa658
UpToDate, Wolters Kluwer Health - 2012-12-03
To What Extent Can Mathematical Modeling Inform the Design of Clinical Trials? The Example of Safe Dose Reduction of Tyrosine Kinase Inhibitors in Responding Patients ...
Charles Schiffer, MD, Haematologica
https://www.doximity.com/articles/4681238f-f736-4d40-8426-f4cf919fa658
UpToDate, Wolters Kluwer Health - 2012-09-25
To What Extent Can Mathematical Modeling Inform the Design of Clinical Trials? The Example of Safe Dose Reduction of Tyrosine Kinase Inhibitors in Responding Patients ...
Charles Schiffer, MD, Haematologica
https://www.doximity.com/articles/4681238f-f736-4d40-8426-f4cf919fa658
UpToDate, Wolters Kluwer Health - 2012-05-07
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Authored Content

Promoting Apoptosis with Venetoclax — A Benefit for Older Patients with AMLAugust 2020

Press Mentions

Combo Protocol Promising for Older AML PatientsAugust 13th, 2020
ASH to Present 2024 Honorific Awards at Annual MeetingNovember 22nd, 2024

Grant Support

Transfusion Trial To Prevent Platelet AlloimmunizationNational Heart, Lung, And Blood Institute1994–1995
Mechanisms Of Drug Resistance In Acute Myeloid LeukemiaNational Cancer Institute1990–1994
Transfusion Trial To Prevent Platelet AllolimmunizationNational Heart, Lung, And Blood Institute1989–1993
Mechanisms Of Platelet RefractorinessNational Heart, Lung, And Blood Institute1986–1988