CharlesJ.RyanMD

Oncology • Middletown, NJ

Genitourinary Oncology, Hematologic Oncology

Member and Attending Genitourinary Oncology Service Memorial Sloan Kettering Cancer Center

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Office
480 Red Hill Road
Middletown, NJ 07748

Education & Training

Memorial Sloan Kettering Cancer CenterFellowship, Hematology and Medical Oncology, 2000 - 2003
University of Wisconsin Hospitals and ClinicsResidency, Internal Medicine, 1996 - 2000
University of Wisconsin School of Medicine & Public HealthClass of 1996

Certifications & Licensure

CA State Medical License 2003 - 2026
NY State Medical License 2000 - 2026
NJ State Medical License 2024 - 2025
MN State Medical License 2018 - 2023

Awards, Honors, & Recognition

CMS Meaningful Use Stage 1 Certification EpicCare Ambulatory EMR, Epic Systems Corporation, 2012-2013

Clinical Trials

Ketoconazole, Hydrocortisone, and GM-CSF in Treating Patients With Progressive Prostate Cancer After Hormone Therapy Start of enrollment: 2004 Apr 01
Completed
Phase 2
Nordihydroguaiaretic Acid in Treating Patients With Nonmetastatic Relapsed Prostate Cancer Start of enrollment: 2005 Jun 01
Terminated
Phase 1
Sorafenib and RAD001 Renal Cell Carcinoma Start of enrollment: 2006 Oct 01
Completed
Phase 1
Sandostatin for Patients With Androgen Independent Prostate Cancer Start of enrollment: 2007 Jul 01
Terminated
Phase 2
Ketoconazole and Dexamethasone in Prostate Cancer Start of enrollment: 2009 Dec 11
Completed
Phase 2
Abiraterone Post Ketoconazole for Prostate Cancer Start of enrollment: 2010 Sep 10
Completed
Phase 2
Neoadjuvant BKM120 in High-risk Prostate Cancer Start of enrollment: 2013 Apr 23
Terminated
Phase 2
A Multicenter Phase I/II Trial of Abiraterone Acetate + BEZ235 in Metastatic, Castration-Resistant Prostate Cancer Start of enrollment: 2013 Jan 31
Terminated
Phase 1, Phase 2
Selinexor in Treating Patients With Abiraterone Acetate and/or Enzalutamide Refractory Metastatic Castration-Resistant Prostate Cancer Start of enrollment: 2014 Sep 02
Terminated
Phase 2
Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide Start of enrollment: 2021 Aug 17
Recruiting
Phase 2
INTense ExeRcise for surviVAL Among Men With Metastatic Prostate Cancer (INTERVAL - GAP4) Start of enrollment: 2016 Jan 01
Active, not recruiting
Not Applicable
Roles: Contact, Principal Investigator
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Publications & Presentations

PubMed

192 citations
Androgen Receptor Rediscovered: The New Biology and Targeting the Androgen Receptor Therapeutically
Charles J. Ryan, Donald J. Tindall
Journal of Clinical Oncology. 2011-09-20
213 citations
Genomic Hallmarks and Structural Variation in Metastatic Prostate Cancer.
David A Quigley, Ha X Dang, Shuang G Zhao, Paul Lloyd, Rahul Aggarwal
Cell. 2018-07-26
47 citations
Impact of Baseline Corticosteroids on Survival and Steroid Androgens in Metastatic Castration-resistant Prostate Cancer: Exploratory Analysis from COU-AA-301
Bruce Montgomery, Thian Kheoh, Arturo Molina, Jinhui Li, Joaquim Bellmunt
European Urology. 2015-05-01

Lectures

Considerations for Systemic Therapy in Optimal Management of Oligometastatic Disease
ASCO Annual Meeting 2019 - Chicago, IL - 6/2/2019

Other

Castrate resistant prostate cancer: Treatments targeting the androgen pathway
Ryan CJ, Dawson NA
http://www.uptodate.com/contents/castrate-resistant-prostate-cancer-treatments-targeting-the-androge
UpToDate, Wolters Kluwer Health - 2013-02-21

Press Mentions

The Prostate Cancer Foundation Launches ‘Black Men: Know Your Risk’ Campaign and Teams up with Atlanta Hawks for ‘Black History Month Assist Challenge’ to Raise Awareness and Funds for Prostate Cancer ResearchFebruary 1st, 2023
Prostate Cancer Foundation Establishes Expert Health Equities Panel Creating Prostate Cancer Screening Guidelines for Black Men in the US - Michael Milken, Isla Garraway, & Kneeland YoungbloodJanuary 13th, 2023
Depression, Bone Health and Exercise in Prostate Cancer - Fred Saad, Tomasz Beer & Charles RyanJune 27th, 2022
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