CarlGriffinMD

Clinical Trials

• A Study of Health Care Use and Costs in Participants With Early Stage Alzheimer's Disease (AD) Start of enrollment: 2016 Oct 29

  Active, not recruiting

• A Phase 3 Trial of the VLP-Based Chikungunya Vaccine PXVX0317 Start of enrollment: 2021 Sep 29

  Completed

  Phase 3

• A Study to Evaluate the Efficacy, Immune Response, and Safety of a COVID-19 Vaccine in Adults ≥ 18 Years With a Pediatric Expansion in Adolescents (12 to<18 Years) at Risk for SARS-CoV-2 Start of enrollment: 2020 Dec 27

  Completed

  Phase 3

• A Study to Evaluate Efficacy, Safety, and Immunogenicity of mRNA-1273 Vaccine in Adults Aged 18 Years and Older to Prevent COVID-19 Start of enrollment: 2020 Jul 27

  Completed

  Phase 3

• A Study to Evaluate the Safety, Reactogenicity, and Effectiveness of mRNA-1273 Vaccine in Adolescents 12 to <18 Years Old to Prevent COVID-19 Start of enrollment: 2020 Dec 09

  Active, not recruiting

  Phase 2, Phase 3

• A Study to Evaluate Safety and Effectiveness of mRNA-1273 COVID-19 Vaccine in Healthy Children Between 6 Months of Age and Less Than 12 Years of Age Start of enrollment: 2021 Mar 15

  Completed

  Phase 2, Phase 3

• A Study to Evaluate the Immunogenicity and Safety of mRNA Vaccine Boosters for SARS-CoV-2 (COVID-19) Variants Start of enrollment: 2021 May 28

  Completed

  Phase 2, Phase 3

• A Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1647 Cytomegalovirus (CMV) Vaccine in Healthy Participants 16 to 40 Years of Age Start of enrollment: 2021 Oct 26

  Active, not recruiting

  Phase 3

• Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis (ADvocate1) Start of enrollment: 2019 Sep 24

  Completed

  Phase 3

• A Study to Evaluate the Effect of Testosterone Replacement Therapy (TRT) on the Incidence of Major Adverse Cardiovascular Events (MACE) and Efficacy Measures in Hypogonadal Men Start of enrollment: 2018 May 03

  Completed

  Phase 4

• A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis Start of enrollment: 2018 Sep 05

  Completed

  Phase 3

• A Study to Test if Fremanezumab is Effective in Preventing Chronic Migraine in Patients 6 to 17 Years of Age Start of enrollment: 2020 Jul 30

  Recruiting

  Phase 3

• A Study to Test if Fremanezumab is Effective in Preventing Episodic Migraine in Patients 6 to 17 Years of Age Start of enrollment: 2020 Jul 15

  Completed

  Phase 3

• A Study to Test if Fremanezumab is Effective in Preventing Migraine in Children and Adolescents Start of enrollment: 2020 Sep 16

  Recruiting

  Phase 3

• A Study of an Ad26.RSV.preF-based Regimen in the Prevention of Reverse Transcriptase Polymerase Chain Reaction (RT-PCR)-Confirmed Respiratory Syncytial Virus (RSV)-Mediated Lower Respiratory Tract Disease in Adults Aged 65 Years and Older Start of enrollment: 2019 Aug 01

  Terminated

  Phase 2

• A Study of an Adenovirus Serotype 26 Pre-fusion Conformation-stabilized F Protein (Ad26. RSV. preF) Based Respiratory Syncytial Virus (RSV) Vaccine in the Prevention of Lower Respiratory Tract Disease in Adults Aged 60 Years and Older Start of enrollment: 2021 Jul 21

  Completed

  Phase 3

• A Study of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Start of enrollment: 2020 Nov 12

  Completed

  Phase 3

• 221AD302 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease Start of enrollment: 2015 Sep 15

  Terminated

  Phase 3

• 221AD301 Phase 3 Study of Aducanumab (BIIB037) in Early Alzheimer's Disease Start of enrollment: 2015 Aug 13

  Terminated

  Phase 3

• Evaluation of Upadacitinib in Adolescent and Adult Patients With Moderate to Severe Atopic Dermatitis (Eczema) Start of enrollment: 2018 Aug 13

  Active, not recruiting

  Phase 3

• A Study to Evaluate the Efficacy and Safety of Bimekizumab in Adult Subjects With Moderate to Severe Chronic Plaque Psoriasis Start of enrollment: 2018 Jan 26

  Completed

  Phase 3

• Study of the Safety and Effectiveness of Two Doses of Investigational Study Drug EVP-6124 in Subjects With Alzheimer's Disease Start of enrollment: 2013 Oct 01

  Terminated

  Phase 3

• Protective Efficacy of Flublok® Quadrivalent Versus Licensed Inactivated Influenza Vaccine in Adults ≥50 Years of Age Start of enrollment: 2014 Oct 01

  Completed

  Phase 3

• Phase 3 Pivotal Trial of NanoFlu™ in Older Adults Start of enrollment: 2019 Oct 14

  Completed

  Phase 3

• A STUDY OF A RSV VACCINE WHEN GIVEN TOGETHER WITH TDAP IN HEALTHY NONPREGNANT WOMEN AGED BETWEEN 18 TO 49 YEARS Start of enrollment: 2019 Oct 01

  Completed

  Phase 2

• Trial to Evaluate the Safety and Immunogenicity of a 20-Valent Pneumococcal Vaccine in Adults 65 Years of Age or Older With Prior Pneumococcal Vaccination Start of enrollment: 2019 Feb 12

  Completed

  Phase 3

• Trial to Evaluate the Safety and Immunogenicity of a 20-valent Pneumococcal Conjugate Vaccine in Pneumococcal Vaccine-naïve Adults Start of enrollment: 2018 Dec 12

  Completed

  Phase 3

• A Study to Evaluate Long-Term Maintenance Treatment With Once Daily Crisaborole Ointment 2% in Pediatric and Adult Participants With Mild-to-Moderate Atopic Dermatitis Start of enrollment: 2019 Sep 12

  Completed

  Phase 3

• Study to Investigate Efficacy and Safety of PF-04965842 in Subjects Aged 12 Years and Over With Moderate to Severe Atopic Dermatitis With the Option of Rescue Treatment in Flaring Subjects Start of enrollment: 2018 Jun 11

  Completed

  Phase 3

• Study to Evaluate Efficacy and Safety of PF-04965842 With or Without Topical Medications in Subjects Aged 12 Years and Older With Moderate to Severe Atopic Dermatitis Start of enrollment: 2018 Mar 08

  Active, not recruiting

  Phase 3

• A Phase 3, Vehicle-controlled Efficacy and Safety Study of IDP-123 Lotion in the Treatment of Acne Vulgaris (302) Start of enrollment: 2017 Jul 11

  Completed

  Phase 3

• Study Comparing the Safety and Efficacy of IDP-120 Gel and IDP-120 Vehicle Gel in the Treatment of Acne Vulgaris Start of enrollment: 2018 Dec 05

  Completed

  Phase 3

• Evaluation of the Efficacy and Safety of Lebrikizumab (LY3650150) in Moderate to Severe Atopic Dermatitis Start of enrollment: 2019 Oct 29

  Completed

  Phase 3

• Evaluation Of Clostridium Difficile Vaccine Lot Consistency In Healthy Adults 65 To 85 Years Of Age Start of enrollment: 2018 Jul 31

  Completed

  Phase 3

• Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE) Start of enrollment: 2018 Jul 09

  Completed

  Phase 3

• Evaluating the Effects of Tradipitant vs. Placebo in Atopic Dermatitis (EPIONE2) Start of enrollment: 2019 Oct 21

  Terminated

  Phase 3

• Study to Assess Safety and Effectiveness of Branebrutinib Treatment in Participants With Active Systemic Lupus Erythematosus or Primary Sjögren's Syndrome, or Branebrutinib Treatment Followed by Open-label Abatacept Treatment in Study Participants With Active Rheumatoid Arthritis Start of enrollment: 2020 Jan 07

  Completed

  Phase 2

• A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate STS101 in the Acute Treatment of Migraine Start of enrollment: 2019 Jun 24

  Completed

  Phase 3

• A Phase 3 STudy of CaPRe in LOwering Very hiGh TriglYcerides (TRILOGY 2) Start of enrollment: 2018 Feb 01

  Completed

  Phase 3

• Efficacy & Safety of Abaloparatide-Solid Microstructured Transdermal System in Postmenopausal Women With Osteoporosis Start of enrollment: 2019 Aug 05

  Completed

  Phase 3

• Study to Evaluate ASN002 in Subjects With Moderate To Severe Chronic Hand Eczema Start of enrollment: 2019 Jan 03

  Completed

  Phase 2

• A Patient-Centric, Prospective, Observational, Non-Interventional Switch Study of XYWAV in Narcolepsy Start of enrollment: 2021 Apr 09

  Completed

• Study to Assess the Effect of Long-term Treatment With Voxelotor in Participants Who Have Completed Treatment in Study GBT440-031 Start of enrollment: 2018 Jun 06

  Active, not recruiting

  Phase 3

• Study to Evaluate the Effect of Voxelotor Administered Orally to Patients With Sickle Cell Disease (GBT_HOPE) Start of enrollment: 2016 Dec 01

  Completed

  Phase 3

• A Study of Donanemab (LY3002813) in Participants With Early Alzheimer's Disease (TRAILBLAZER-ALZ 2) Start of enrollment: 2020 Jun 19

  Active, not recruiting

  Phase 3

• A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease Start of enrollment: 2022 Jun 02

  Active, not recruiting

  Phase 3

• Efficacy, Safety, and Pharmacokinetic Profile of Etokimab (ANB020) in Adult Participants With Moderate-to-Severe Atopic Dermatitis Start of enrollment: 2018 Jun 19

  Completed

  Phase 2

• Efficacy and Safety of 26-Week Treatment of AR1001 in Patients With Mild to Moderate Alzheimer's Disease Start of enrollment: 2019 Apr 01

  Completed

  Phase 2

• A Trial to Describe the Immunogenicity and Safety of 2 Doses of Bivalent rLP2086 (Trumenba) and a Pentavalent Meningococcal Vaccine in Healthy Subjects >=10 to <26 Years of Age. Start of enrollment: 2017 Apr 24

  Completed

  Phase 3

• Comparison of Efficacy, Safety, and Tolerability of ITCA 650 to Empagliflozin and Glimepiride as add-on Metformin Start of enrollment: 2017 Mar 03

  Terminated

  Phase 3

• AGN-242428 in the Treatment of Plaque Psoriasis Start of enrollment: 2017 Nov 15

  Terminated

  Phase 2

• A 4-Week Study of the Safety, Efficacy, and Pharmacokinetics of JZP-110 [(R)-2-amino-3-phenylpropylcarbamate Hydrochloride] in Subjects With Parkinson's Disease and Excessive Sleepiness Start of enrollment: 2017 Jan 01

  Completed

  Phase 2

• Trial to Evaluate the Safety and Immunogenicity of a Multivalent Pneumococcal Conjugate Vaccine in Adults 60 Through 64 Years of Age Start of enrollment: 2017 Oct 10

  Completed

  Phase 2

• A Study to Evaluate the Safety and Efficacy of Topically Applied TV 45070 Ointment in Patients With Postherpetic Neuralgia (PHN) Start of enrollment: 2015 Feb 26

  Completed

  Phase 2

• Safety, Tolerability, and Immunogenicity of Two Formulations of V114 in Healthy Adults 50 Years of Age or Older (V114-006) Start of enrollment: 2015 Oct 08

  Completed

  Phase 2

• Efficacy and Safety Trial of Verubecestat (MK-8931) in Participants With Prodromal Alzheimer's Disease (MK-8931-019) Start of enrollment: 2013 Nov 05

  Terminated

  Phase 3

• Safety and Efficacy of Suvorexant (MK-4305) for the Treatment of Insomnia in Participants With Alzheimer's Disease (MK-4305-061) Start of enrollment: 2016 May 23

  Completed

  Phase 3

• A Study to Assess the Addition of Sitagliptin to Metformin Compared With the Addition of Dapagliflozin to Metformin in Participants With Type 2 Diabetes Mellitus (T2DM) and Mild Renal Impairment Who Have Inadequate Glycemic Control on Metformin With or Without a Sulfonylurea (MK-0431-838) Start of enrollment: 2015 Oct 20

  Completed

  Phase 3

• Efficacy in Controlling Glycaemia With Victoza® (Liraglutide) as add-on to Metformin vs. OADs as add-on to Metformin After up to 104 Weeks of Treatment in Subjects With Type 2 Diabetes Start of enrollment: 2016 Mar 28

  Completed

  Phase 4

• Dose-finding of Semaglutide Administered Subcutaneously Once Daily Versus Placebo and Liraglutide in Subjects With Type 2 Diabetes Start of enrollment: 2015 Sep 21

  Completed

  Phase 2

• Efficacy and Safety of Oral Semaglutide Versus Placebo in Subjects With Type 2 Diabetes Mellitus Treated With Diet and Exercise Only Start of enrollment: 2016 Sep 20

  Completed

  Phase 3

• A Phase 3 Study of Tanezumab for Chronic Low Back Pain Start of enrollment: 2015 Aug 18

  Completed

  Phase 3

• Study to Evaluate the Safety and Efficacy of USL261 (Intranasal Midazolam) in Patients With Seizure Clusters Start of enrollment: 2011 Jun 01

  Terminated

  Phase 3

• Safety and Immunogenicity of High-Dose Quadrivalent Influenza Vaccine in Participants ≥65 Years in the US Start of enrollment: 2017 Sep 08

  Completed

  Phase 3

• Safety and Efficacy of Bexagliflozin in Type 2 Diabetes Mellitus Patients With Moderate Renal Impairment Start of enrollment: 2016 Sep 23

  Completed

  Phase 3

• A Study to Examine the Safety and Efficacy of a New Drug in Patients With Symptoms of Overactive Bladder (OAB) Start of enrollment: 2018 Mar 26

  Completed

  Phase 3

• A Study of Tocilizumab in Comparison to Etanercept in Participants With Rheumatoid Arthritis and Cardiovascular Disease Risk Factors Start of enrollment: 2011 Aug 02

  Completed

  Phase 4

• Efficacy and Tolerability of Topical LFX453 for External Genital Warts Start of enrollment: 2015 May 12

  Completed

  Phase 2

• Second Plecanatide Study In Irritable Bowel Syndrome With Constipation (IBS-C) Start of enrollment: 2015 Jun 01

  Completed

  Phase 3

• Long Term Safety Study of Plecanatide Start of enrollment: 2016 Jan 01

  Completed

  Phase 3

• Evaluate the Effect of Aclidinium Bromide on Long-term Cardiovascular Safety and Exacerbations in Moderate to Very Severe COPD Patients. Start of enrollment: 2013 Oct 16

  Completed

  Phase 4

• Study to Evaluate the Safety of Long-Term Use of Perforomist® (Formoterol Fumarate) Start of enrollment: 2012 Mar 01

  Completed

  Phase 4

• A Clinical Trial to Study the Safety, Tolerance and Immunogenic Response to Gardasil and Bivalent rLP2086 Vaccine When Given at the Same Time to Children Between the Ages of 11 and 17 Start of enrollment: 2011 Sep 28

  Completed

  Phase 2

• Cardiovascular Outcomes Study of Naltrexone SR/Bupropion SR in Overweight and Obese Subjects With Cardiovascular Risk Factors (The Light Study) Start of enrollment: 2012 Jun 01

  Terminated

  Phase 3

• Cardiovascular and Renal Microvascular Outcome Study With Linagliptin in Patients With Type 2 Diabetes Mellitus (CARMELINA) Start of enrollment: 2013 Jul 10

  Completed

  Phase 4

• Multi-Center Study to Assess the Efficacy and Safety of PT003, PT005, and PT001 in Subjects With Moderate to Very Severe COPD (PINNACLE 2) Start of enrollment: 2013 Jul 01

  Completed

  Phase 3

• Monthly And Twice Monthly Subcutaneous Dosing Of PF-04950615 (RN316) In Hypercholesterolemic Subjects On A Statin Start of enrollment: 2012 Jul 01

  Completed

  Phase 2

• Study of Idalopirdine in Patients With Mild - Moderate Alzheimer's Disease Treated With Donepezil Start of enrollment: 2013 Oct 01

  Completed

  Phase 3

• This Was a Multinational Study Comparing the Efficacy and Safety of Two Medicines , Solifenacin Succinate and Mirabegron Taken Together, or Separately, or a Mock Treatment (Placebo) in Subjects With Symptoms of Overactive Bladder Start of enrollment: 2013 Nov 05

  Completed

  Phase 3

• Tiotropium +Olodaterol Fixed Dose Combination (FDC) Versus Tiotropium and Olodaterol in Chronic Obstructive Pulmonary Disease (COPD) Start of enrollment: 2011 Sep 01

  Completed

  Phase 3

• A Study to Evaluate Cardiovascular Outcomes in Patients With Type 2 Diabetes Treated With ITCA 650 Start of enrollment: 2013 Mar 01

  Completed

  Phase 3

• A Study of Lebrikizumab in Participants With Uncontrolled Asthma Who Are on Inhaled Corticosteroids and a Second Controller Medication Start of enrollment: 2013 Jul 31

  Completed

  Phase 3

• Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of PF-06649751 in Parkinson's Disease Start of enrollment: 2014 Oct 01

  Completed

  Phase 1

• Placebo-controlled Safety and Efficacy Study of Pregabalin in Subjects With Post-traumatic Peripheral Neuropathic Pain Start of enrollment: 2012 Oct 01

  Completed

  Phase 3

• Trial of Linaclotide in Patients With Chronic Idiopathic Constipation Start of enrollment: 2014 Oct 01

  Completed

  Phase 3

• Efficacy and Safety of Subcutaneous Administration of Fremanezumab (TEV-48125) for the Preventive Treatment of Migraine Start of enrollment: 2016 Feb 26

  Completed

  Phase 3

• Safety, Reactogenicity, and Immunogenicity Trial of CV2CoV mRNA Vaccine Against SARS-CoV-2 in Seropositive Adult Participants Start of enrollment: 2022 Mar 24

  Completed

  Phase 1

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