CKeithOzakiMD

PubMed

• 217 citations
  Amino Acid Restriction Triggers Angiogenesis via GCN2/ATF4 Regulation of VEGF and H2S Production.
  Alban Longchamp, Teodelinda Mirabella, Alessandro Arduini, Michael R MacArthur, Abhirup Das
  Cell. 2018-03-22
• 166 citations
  Regulation of Arterial Thrombolysis by Plasminogen Activator Inhibitor-1 in Mice
  Peter Farrehi, C. Keith Ozaki, Peter Carmeliet, William P. Fay
  Circulation. 1998-03-17
• 21 citations
  Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Promotes Macrophage Activation via LDL Receptor-Independent Mechanisms.
  Shunsuke Katsuki, Prabhash K Jha, Adrien Lupieri, Toshiaki Nakano, Livia S A Passos
  Circulation Research. 2022-11-11

Journal Articles

• Strategies and Outcomes for Aortic Endograft Explantation  
  C Ozaki, MD, Journal of Vascular Surgery
• Is overnight fasting before surgery too much or not enough? How basic aging research can guide preoperative nutritional recommendations to improve surgical outcomes: a...  
  Longchamp A, Harputlugil E, Corpataux JM, Ozaki CK, Mitchell JR, Gerontology, 1/1/2017
• Systematic identification and management of barriers to vascular surgery patient discharge time of day  
  Sharma G, Wong D, Arnaoutakis D, Shah SK, Obrien A, Ashley S, Ozaki CK, J Vasc Surg, 1/1/2017
• Impact of body mass index and gender on wound complications after lower extremity arterial surgery  
  Arnaoutakis D, Scully RE, Sharma G, Shah SK, Hamdan AD, Barshes NR, Belkin MB, Ozaki CK, Nguyen LL, J Vasc Surg, 1/1/2017
• Hypothalamic-Pituitary axis regulates hydrogen sulfide production  
  Hine C, Kim HJ, Zhu Y, Harputlugil E, Longchamp A, Matos MS, Ramadoss P, Bauerle K, Brace L, Asara JM, Ozaki CK, Cheng SY, Singha S, Ahn KH, Kimmelman A, Fisher Fm, Pi..., Cell Metab, 1/1/2017
• Meta-analysis of individual-patient data from EVAR-1, DREAM, OVER and ACE trials comparing outcomes of endovascular or open repair for abdominal aortic aneurysm over 5...  
  Powell JT, Sweeting MJ, Ulug P, Blankenstein JD, Lederle FA, Becquemin JP, Greenhalgh RM; EVAR-1, DREAM, OVER and ACE Trialists, Br J Surg, 1/1/2017
• Activation of TRPV1 accelerates reendothelialization and inhibits neointimal formation following vascular injury  
  Ozaki CK, J Vasc Surg, 1/1/2017
• Tilting at the tilted preotease balance in arterial aneurysmal disease  
  Libby P, Sukhova G, Ozaki CK, Shi G, Cardiovascular Research, 1/1/2017
• The impact of vascular surgery wound complications on quality of life  
  McGillicuddy EA, Ozaki CK, Shah SK, Belkin M, Hamdan A, Barshes N, Wyers M, Nguyen LL, J Vasc Surg, 1/1/2016
• Perioperative outcomes of elective inflow revascularization for lower extremity claudication in the American College of Surgeons National Surgical Quality Improvement ...  
  Madenci AL, Ozaki CK, Gupta N, Raffetto JD, Belkin M, McPhee JT, Am J Surg, 1/1/2016
• Local perivascular adiponectin associates with lower extremity vascular surgery wound complications  
  Sharma G, Kulkarni R, Shah SK, King WW, Longchamp A, Tao M, Ding K, Ozaki CK, Surgery, 1/1/2016
• Pre-operative dietary restriction reduces intimal hyperplasia and protects from ischemia reperfusion  
  Mauro CR, Tao M, Yu P, Trevino-Villerreal JH, Longchamp A, Kristal BS, Ozaki CK, Mitchell JR, J Vasc Surg, 1/1/2016
• Adipose phenotype predicts human arteriovenous fistula remodeling  
  Mauro C, Ding K, Xue H, Tao M, Longchamp A, Belkin M, Kristal B, Ozaki CK, J Vasc Surg, 1/1/2016
• Perivascular adipose adiponectin correlates with symptoms status of patients undergoing carotid endarterectomy  
  Sharma G, Tao M, Ding M, Yu D, King W, Deyneko G, Wang X, Longchamp A, Schoen FJ, Ozaki CK, Semel ME, Stroke, 1/1/2015
• Prospective, randomized, multi-institutional clinical trial of a silver alginate dressing to reduce lower extremity vascular surgery wound complications  
  Ozaki CK, Hamdan A, Barshes NR, Wyers MC, Hevelone ND, Belkin M, Nguyen LL, J Vasc Surg, 1/1/2015
• Protein and calorie restriction contribute additively to protection from renal ischemia reperfusion injury partially via leptin reduction in male mice  
  Robertson LT, Trevino-Villerreal JH, Mejia P, Grondin Y, Harputlugil E, Hine C, Vargas D, Zheng H, Kristal BS, Ozaki CK, Simpson SJ, Mitchell JR, J Nutr, 1/1/2015
• Conexin43 inhibition prevents human vein graft intimal hyperplasia  
  Longchamp A, Allagnat F, Alonso F, Kuppler C, Dubuis C, Ozaki CK, Berceli S, Corpataux J, Declise S, Haefliger J, PLoS One, 1/1/2015
• Macrophage Notch ligand Delta-like 4 promotes the lesion development of vein grafts in LDL receptor-deficient mice: implications for the treatment of vein graft failure  
  Koga J, Figueiredo J, Dahlman JE, Niida T, Iwata H, Aster JC, Yagita H, Anderson DG, Ozaki CK, and Aikawa M, Arterioscler Thromb Vasc Biol, 1/1/2015
• Surgical injury induces local and distant adipose tissue browning  
  Longchamp A, Tao M, Bartlelt A, Ding K, Lynch L, Hine C, Corpataux J, Kristal BS, Mitchell JR, Ozaki CK, Adipocyte, 1/1/2015
• Costs of repair of abdominal aortic aneurysm with different devices in a multicenter randomized trial  
  Matsumura JS, Stroupe KT, Lederle FA, Kyriakides TC, Ge L, Freischlag JA, for the Open Versus Endovascular Repair (OVER) Veterans Affairs Cooperative Study Group, J Vasc Surg, 1/1/2015
• Cathepsin G deficiency reduces peri-aortic calcium chloride injury-induced abdominal aortic aneurysms in mice  
  Wang J, Sukhova GK, Liu J, Ozaki CK, Lesner A, Libby P, Kovanen PT, Shi GP, J Vasc Surg, 1/1/2015
• Cost-effectiveness of revascularization for limb preservation in patients with marginal functional status  
  Barshes NR, Kougias P, Ozaki CK, Pisimisis G, Bechara CF, Henson HK, Belkin M, Ann Vasc Surg, 1/1/2014
• Central role for hydrogen peroxide in P2Y1 ADP receptor-mediated cellular responses in vascular endothelium  
  Kalwa H, Sartoretto J, Martinelli R, Romero N, Steinhorn B, Tao M, Ozaki CK, Carman C, Michel T, Proc Nat Acad Sci, 1/1/2014
• Diet-induced obesity drives negative mouse vein graft wall remodelling  
  Yu P, Nguyen BT, Tao M, Jiang T, Ozaki CK, J Vasc Surg, 1/1/2014
• Acute reductions in mechanical wall strain preceded the formation of intimal hyperplasia in a murine model of arterial occlusive disease  
  Favreau JT, Liu C, Yu P, Tao M, Mauro CR, Gaudette GR, Ozaki CK, J Vasc Surg, 1/1/2014
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Books/Book Chapters

• Current Vascular Surgery 
  Chapter: Management of infected AV grafts 
  Page 193.0 - 198.0Shah SK, Ozaki CKEditors: Eskandari MK, Pearce WH, Yao JST.People’s Medical Publishing House, Shelton, CT2016
• Master Techniques in Surgery: Vascular Surgery 
  Chapter: Ankle disarticulation and circular open (guillotine) below knee amputation 
  Page 255.0 - 260.0Ozaki CKEditors: Darling III RC and Ozaki CK.Lippincott-Williams and Wilkins, Philadelphia2016
• Clinical Scenarios in Vascular Surgery 
  Chapter: Cerebral hyperfusion after carotid endarterectomy 
  Page 25.0 - 28.0Semel ME, Liangge H, and Ozaki CKEditors: Upchurch G, Henke P.Lippincott Williams and Wilkins, PhiladelphiaEdition 2nd,2015
• Current Problems in Surgery 
  Chapter: Introduction 
  Page 198.0 - 201.0Ozaki CKEditors: Ashley SW.Elsevier, Maryland Heights, MO2014
• Current Problems in Surgery 
  Chapter: In brief 
  Page 194.0 - 196.0Ozaki CKEditors: Ashley SW.Elsevier, Maryland Heights, MO2014
• Rutherford’s Vascular Surgery 
  Chapter: Intimal hyperplasia 
  Page 78.0 - 86.0Jiang Z, Ozaki CKEditors: Cronenwett JL and Johnston, KW.Elsevier, Maryland Heights, MOEdition 8th,2014
• Current Therapy in Vascular and Endovascular Surgery 
  Chapter: Buerger’s Disease 
  Page 194.0 - 196.0Kristo G, Ozaki CKEditors: Stanley JC, et al.Elsevier, Maryland Heights, MOEdition 5th,2014
• Current Surgical Therapy 
  Chapter: The treatment of claudication 
  Page 888.0 - 892.0Barshes NR, Ozaki CKEditors: Cameron JL and Cameron AM.Elsevier, Maryland Heights, MOEdition 11th,2014
• Mastery of Surgery 
  Chapter: Superior mesenteric artery embolectomy and bypass for acute mesenteric ischemia 
  Page 2371. - 2377.Ozaki CK, Kelly EEditors: Fischer JE et al.Lippincott-Williams and Wilkins, PhiladelphiaEdition 6th,2011
• General Surgery: Principals and International Practice 
  Chapter: Vascular access for hemodialysis 
  Page 1861. - 1866.Ozaki CKEditors: Bland KI et al.Springer, London2009
• Mastery of Surgery 
  Chapter: Superior mesenteric artery embolectomy 
  Page 2142. - 2145.Ozaki CKEditors: Fischer JE et al.Lippincott-Williams and Wilkins, PhiladelphiaEdition 5th,2007
• Vascular Surgery 
  Chapter: Vascular access 
  Page 141.0 - 148.0Mitchell D, Ozaki CKEditors: Davies A, Brophy C.Springer, London2006
• Mastery of Vascular and Endovascular Surgery 
  Chapter: Vascular biology: atherosclerosis and intimal hyperplasia 
  Page 3.0 - 8.0Jiang Z, Berceli SA, Ozaki CKEditors: Zelenock GB, Lumsden AB, Messina LM, Moneta GL, Huber TS.Lippincott-Williams and Wilkins, Philadelphia2006
• Vascular Access for Hemodialysis—IX 
  Chapter: Radiation therapy for improved dialysis access patency—safety and feasibility 
  Page 267.0 - 275.0Ozaki CK, Berceli SA, Irwin AS, Huber TS, Seeger JM, Lee WA, Flynn TC, Palta JR, Mendenhall NP, Zlotecki RAEditors: Henry ML.Bonus Books, Los Angeles2005
• Greenfield’s Surgery: Scientific Principals and Practice 
  Chapter: Abdominal aortic aneurysms 
  Page 1711. - 1747.Huber TS, Ozaki CK, Lee WA, Seeger JMEditors: Mulholland MW.Lippincott-Williams and Wilkins, Philadelphia2005
• Clinical Scenarios of Vascular Surgery 
  Chapter: Cerebral hyperfusion syndrome after carotid endarterectomy 
  Page 31.0 - 35.0Ozaki CKEditors: Upchurch G, Henke P.Lippincott Williams and Wilkins, Philadelphia2002
• The Practice of General Surgery 
  Chapter: Vascular access for hemodialysis 
  Page 1208. - 1212.Ozaki CKEditors: Bland KI.W.B. Saunders Company, Philadelphia2002
• Surgery: Scientific Principals and Practice 
  Chapter: Abdominal aortic aneurysms 
  Page 1803. - 1833.Huber TS, Ozaki CK, Seeger JMEditors: Greenfield LJ.Lippincott-Williams and Wilkins, Philadelphia2001
• Current Therapy in Vascular Surgery 
  Chapter: Buerger’s Disease 
  Page 151.0 - 154.0Ozaki CK, Seeger JMEditors: Ernst CB, Stanley JC.Mosby, Philadelphia2001
• Surgical Care for the Elderly 
  Chapter: Vascular surgery in the elderly patient 
  Page 241.0 - 249.0Ozaki CK, Greenfield LJEditors: Adkins RB Jr., Scott HW, Jr.Lippincott-Raven Publishers, PhiladelphiaEdition 2nd,1998
• Perspectives in Vascular Surgery and Endovascular Therapy 
  Chapter: Magnetic forces enable rapid endothelialization of synthetic vascular grafts; Pislaru SV, et al. Circulation. 2006; 114:I-314-318 
  Ozaki CKEditors: Gloviczki P.SAGE Publications, Thousand Oaks, CA
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Abstracts/Posters

• Protamine Sulfate use does not lower hemorrhagic complications in lower extremity bypass
  McPhee JT, Menard MT, Ho KJ, Ozaki CK, Nguyen LL, Barshes N, Belkin M, Vascular Annual Meeting, Washington, DC, 1/1/2012
• Carotid Artery Stenosis
  Ozaki CK, University of Florida CME Course Caring for the Older Adult II, 1/1/2002
• Surgical injury induces local and distant adipose tissue browning
  Longchamp A, Tao M, Bartlet A, Ding K, Lynch L, Hine C, Corpataux JM, Kristal BS, Mitchell JR, Ozaki CK, Atherosclerosis, Thrombosis, and Vascular Biology, San Francisco, CA, 1/6./2015
• Vein Graft Implantable Contrast Initiative: Enhanced Vessel Wall Imaging
  Miranda OR, Rybicki, FJ, Ozaki CK, Karp J, Yu P, D Mitsouras, Proceedings of the 99th Scientific Assembly and Annual Meeting of the Radiological Society of North America, Chicago, IL, 1/1./2013
• Locally deployed peri-valvular leptin promotes thickening of aortic valve leaflets associated with remodeling of the left ventricl in ApoE deficient mice
  Ben ZD, Fisch S, Ozaki CK, Liao R, Schoen F, Schneiderman J, Atherosclerosis, Thrombosis, and Vascular Biology, Toronto, Canada, 1/1./2014
• Macrophage notch signaling accelerates vein graft disease in Ldlr-/- mice
  Koga J, Figueiredo J, Dahlman JE, Niida T, Iwata H, Anderson DG, Ozaki CK, Aikawa M, 14th Biennial Meeting of the International Society for Applied Cardiovascular Biology, Cleveland, OH, 1/2./2014
• Prospective, randomized, multi-institutional clinical trial of a silver alginate dressing to reduce lower extremity vascular surgery wound complications
  Ozaki CK, Hamdan A, Barshes NR, Wyers MC, Hevelone ND, Beklin M, Nguyen LL, Vascular 2014, Boston, MA, 1/6./2014
• Adipose phenotype predicts human arteriovenous fistula remodeling
  Ding K, Mauro C, Xue H, Tao M, Longchamp A, Kristal B, Belkin M, Ozaki CK, New England Society for Vascular Surgery, Boston, MA, 1/11/2014
• A comparison of the short-term outcomes of elective inflow revascularization for claudicants
  Madenci AL, Ozaki CK, Gupta N, Raffetto JD, Belkin M, McPhee JT, 39th Annual Meeting of the Southern Association for Vascular Surgery, Scottsdale, AZ, 1/14/2015
• Adipose-associated mediators correlate with anatomy and physiologic adaptations following fistula placement: the Hemodialysis Fistula Maturation (HFM) Study
  Kuppler C, Sharma G, He Y, Tao M, Dember L, Ozaki CK, Berceli SA for the Hemodialysis Fistula Maturation Study, Atherosclerosis, Thrombosis, and Vascular Biology, San Francisco, CA, 1/6./2015
• Vascular anatomic and physiologic relationships with local adipose phenotype in chronic kidney disease patients
  Sharma G, Tao M, Ding K, Longchamp A, Hamburg NM, Palmisano JN, Dember LM, Berceli SA, Ozaki CK, Vita JA for the Hemodialysis Fistula Maturation Study, Atherosclerosis, Thrombosis, and Vascular Biology, San Francisco, CA, 1/6./2015
• Cost-effectiveness of exercise therapy versus primary stenting for patients with intermittent claudication and ilio-femoral disease
  Semel ME, Ho KJ, Ozaki CK, Belkin M, New England Society for Vascular Surgery, Stowe, VT, 1/26/2013
• Perivascular adipose adiponectin correlates with symptom status of patients undergoing carotid endarterectomy
  Sharma G, Tao M, Ding M, Yu D, King W, Deyneko G, Wang X, Longchamp A, Schoen FJ, Ozaki CK, Semel ME, Vascular Research Initiatives Conference/Atherosclerosis, Thrombosis, and Vascular Biology, San Francisco, CA, 1/6./2015
• The impact of vascular surgery wound complications on quality of life
  McGillicuddy EA, Ozaki CK, Shah SK, Belkin M, Hamdan A, Barshes N, Wyers M, Nguyen LL, New England Society for Vascular Surgery, Newport, RI, 1/2./2015
• Novel link between cholesterol and hydrogen sulfide production potential in vascular disease patients
  King AA, Longchamp A, Tao M, Kulkarni R, Mitchell JR, Ozaki CK, Sharma G, 11th Annual Academic Surgical Congress, Jacksonville, FL, 1/2./2016
• Baseline adipose phenotype predicts vascular surgery wound complications
  Kulkarni R, King WW, Shah S, Longchamp A, Tao M, Ding K, Ozaki CK, Sharma G, 11th Annual Academic Surgical Congress, Jacksonville, FL, 1/2./2016
• Specific gut microbe-derived metabolite signatures associated with severe human atherosclerosis
  Cason CA, Dolan K, Sharma G, Tao M, Longchamp A, Kulkarni R, Xiong L, Chang EB, McDermott MM, Ozaki CK, Ho KJ, 12th Annual Academic Surgical Congress, Las Vegas, NV, 1/9./2017
• Human adiponectin correlates with severe carotid plaque calcification
  Hurst VT, Deery SE, Sharma G, Coll MD, Tao M, Trocha K, Longchamp A, Ozaki CK, Guzman RJ, 12th Annual Academic Surgical Congress, Las Vegas, NV, 1/9./2017
• Perivascular globular adiponectin attenuates the neointimal response potentially via modulation of hydrogen sulfide
  Trocha K, Tao M, Macarthur MR, Longchamp A, Trevino H, de Vries MR, Mitchell J, Ozaki CK, Vascular Research Initiatives Conference/Atherosclerosis, Thrombosis, and Vascular Biology, Minneapolis, MN, 1/4./2017
• Increased endogenous hydrogen sulfide protects against vein graft disease
  Trocha K, Tao M, Longchamp A, Macarthur MR, Mitchell J, Ozaki CK, de Vries MR, Vascular Research Initiatives Conference/Atherosclerosis, Thrombosis, and Vascular Biology, Minneapolis, MN, 1/4./2017
• Post-anesthetic ultrasound facilitates more preferential hemodialysis access creation without impacting access patency
  McGlynn P, Arnaoutakis D, Deroo EP, Ozaki CK, Hentschel DM, New England Society for Vascular Surgery, Boston, MA, 1/8./2017
• Strategies and Outcomes for Aortic Endograft Explantation
  Arnaoutakis DJ, Sharma G, Blackwood S, Shah, SK, Menard M, Ozaki CK, Belkin DM, New England Society for Vascular Surgery, Boston, MA, 1/8./2017
• Impact of uremia on human adipose phenotye
  Ho KJ, Xue H, Mauro C, Nguyen B, Yu P, Tao M, Brunelli S, Ozaki CK, Atherosclerosis, Thrombosis, and Vascular Biology, Chicago, IL, 1/18/2012
• Techniques for Tibial Artery Exposure and Bypass
  Ozaki CK, Harvard Postgraduate Course in Vascular Surgery, Boston, MA, 1/8./2010
• Acute Lower Extremity Ischemia
  Ozaki CK, Harvard Postgraduate Course Advances in Vascular and Endovascular Surgery: 2013, Boston, MA, 1/25/2013
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Lectures

• Adjustable Resistance Dialysis Access Graft 
  1/1/2011
• Carotid Artery Disease as a Model for Surgical Decision Making 
  Gainesville, FL - 1/1/2004
• Inflammatory Mechanisms of Neointimal Hyperplasia and Arterial Remodeling 
  1/1/2001
• Challenges in Vascular Surgery 
  Gainesville, FL - 1/16/2006
• Abdominal Aortic Aneurysms: Diagnosis and Contemporary Management 
  Worcester, MA - 1/7./2009
• Arterial Disease 
  University of Florida College of Medicine, Gainesville, FL - 1/24/1998
• Venous Disease 
  University of Florida College of Medicine, Gainesville, FL - 1/31/1998
• Acute Renal Failure 
  University of Florida College of Medicine, Gainesville, FL - 1/21/1999
• Carotid Artery Endarterectomy Trials 
  University of Florida College of Medicine, Gainesville, FL - 1/28/1999
• Evidence Based Surgery and Carotid Disease 
  University of Florida College of Medicine, Gainesville, FL - 1/28/2002
• PVOD 
  University of Florida College of Medicine, Gainesville, FL - 1/4./2004
• Evidence Based Decision Making in Vascular Surgery 
  University of Florida College of Medicine, Gainesville, FL - 1/11/2004
• CVOD--Evidence Based Vascular Surgery 
  University of Florida College of Medicine, Gainesville, FL - 1/8./2004
• Evidence Based Vascular Surgery 
  University of Florida College of Medicine, Gainesville, FL - 1/7./2005
• Anastomotic Workshop 
  Brigham and Women’s Hospital, Department of Surgery - 1/11/2013
• Contemporary Management of Peripheral Vascular Occlusive Disease 
  1/29/2009
• How to Write a Fundable Research Grant 
  1/23/2009
• Acute Mesenteric Ischemia 
  1/25/2009
• Introduction to BWH Surgical Resident Research 
  1/1./2010
• Maximizing Your Research Tour 
  1/13/2010
• Grant Writing Strategies and Techniques 
  1/13/2010
• Seminar Series Kickoff; Grant Writing Strategies and Techniques 
  1/12/2011
• Junior Resident Anastomotic Workshop 
  Brigham and Women’s Hospital, Department of Surgery - 1/7./2011
• Senior Resident Anastomotic Workshop 
  Brigham and Women’s Hospital, Department of Surgery - 1/14/2011
• Miscellaneous Vascular Disease 
  1/29/2012
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Other

• Murine models of atherosclerosis and peripheral vascular disease 
  Ozaki CK, Berceli SA
  http://www.vascularweb.org/_CONTRIBUTION_PAGES/Research/Basic_Articles/Murine_models_AS_Ozaki.html
  1/1/2011
• Mouse models of vein graft adaptations 
  Yu P, Nguyen BT, Tao M, Ozaki CK
  http://www.vascularweb.org/research/researchresources/Documents/Mouse_VG_Review-Ozaki-hyperlinked.pdf
  1/1/2011
• What you eat before surgery may affect your recovery (and other similar headlines) 
  Ozaki CK, WCVB TV/WBZ News Radio 1030 CBS/Boston Globe/Metro New York
  Boston - 1/4./2014