BryanDavidKraftMDFCCP

Critical Care Medicine

Associate Professor of Medicine, Director of Medical Critical Care and Medical Intensive Care Units, Washington University School of Medicine in St. Louis

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Office
1 Barnes Jewish Hospital Plz
# Div
Saint Louis, MO 63110
Phone+1 314-454-8762

Fax+1 314-454-7524

Summary

Dr. Kraft has a wide variety of clinical and research interests, including sepsis, pneumonia, and acute respiratory distress syndrome (ARDS), and has special expertise in rare lung diseases such as pulmonary fibrosis and pulmonary alveolar proteinosis (PAP). Dr. Kraft’s research laboratory is devoted to understanding mechanisms of acute lung injury resolution, and uses translational models and clinical patient samples to identify novel pathways of recovery. Dr. Kraft is also an active investigator in clinical trials to develop new therapies for patients with lung diseases.

Education & Training

Duke University HospitalFellowship, Pulmonary Disease and Critical Care Medicine, 2010 - 2013
Duke University HospitalResidency, Internal Medicine, 2007 - 2010
University of Tennessee Health Science Center College of MedicineClass of 2007

Certifications & Licensure

MO State Medical License 2021 - 2026
FL State Medical License 2019 - 2023
NC State Medical License 2007 - 2022
American Board of Internal Medicine Internal Medicine
American Board of Internal Medicine Critical Care Medicine
American Board of Internal Medicine Pulmonary Disease

Clinical Trials

Hyperbaric VO2max Study Start of enrollment: 2015 Feb 01
Terminated
Phase 2
Safety Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS) Start of enrollment: 2015 Apr 01
Completed
Phase 1
Efficacy and Safety of Inhaled Molgramostim (rhGM-CSF) in Autoimmune Pulmonary Alveolar Proteinosis Start of enrollment: 2016 Mar 21
Completed
Phase 2
Safety and Efficacy Study of Inhaled Carbon Monoxide to Treat Acute Respiratory Distress Syndrome (ARDS) Start of enrollment: 2019 Jul 01
Active, not recruiting
Phase 2
Safety Study of Inhaled Carbon Monoxide to Treat Pneumonia and Sepsis-Induced Acute Respiratory Distress Syndrome (ARDS) Start of enrollment: 2023 Dec 06
Recruiting
Phase 1
Roles: Contact
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Publications & Presentations

PubMed

SARS-CoV-2 viremia but not respiratory viral load is associated with respiratory complications in patients with severe COVID-19.
Lingye Chen, Lyra B Olson, Ibtehaj A Naqvi, Bruce A Sullenger, Loretta G Que
BMC Pulmonary Medicine. 2024-07-29
Acute chest syndrome from sickle cell disease successfully supported with veno-venous extracorporeal membrane oxygenation.
John C Grotberg, Mary Sullivan, Rachel K McDonald, Vladimir Despotovic, Chad A Witt
Artificial Organs. 2024-07-01
Extracorporeal Membrane Oxygenation for Respiratory Failure: A Narrative Review.
John C Grotberg, Daniel Reynolds, Bryan D Kraft
Journal of Clinical Medicine. 2024-06-28

Journal Articles

Pulmonary Arterial Hypertension: Screening, Management, and Treatment [Internet]
McCrory DC, Coeytaux RR, Schmit KM, Kraft B, Kosinski AS, Mingo AM, Vann LM, Gilstrap DL, Hargett CW, Lugogo NL, Heidenfelder BL, Posey R, Irvine RJ, Wing L, Pendergas..., Rockville (MD): Agency for Healthcare Research and Quality (US), 4/2013

Books/Book Chapters

Respiratory Care: Principles and Practice
Chapter: Pneumonia
Page 858 - 889Nicholas Wysham, Morgan Mullaney, Bryan D. KraftEditors: Dean R. Hess, Neil R. MacIntyre, William F. Galvin, Shelley C. Mishoe.Jones & Bartlett Learning, Burlington, MAEdition 3rd,2016

Press Mentions

Still No Consensus on Antibiotics for Persistent Sinus InfectionFebruary 6th, 2017
Inhaled CO Is Tested as ARDS TherapyJanuary 31st, 2017
Could Carbon Monoxide Be Used to Manage Sepsis-Related Lung Injury? – an Interview with Bryan Kraft, MDFebruary 22nd, 2019