Bruce Colston Trapnell MD
Critical Care Medicine
Professor, Pediatrics, University of Cincinnati College of Medicine
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222 Piedmont AveSte 6000Cincinnati, OH 45219
Phone+1 513-475-7521
Fax+1 513-475-7327
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Education & Training
Clinical Center at the National Institutes of HealthFellowship, Pulmonary Disease and Critical Care Medicine, 1988 - 1989- Clinical Center at the National Institutes of HealthFellowship, Pulmonary Disease and Critical Care Medicine, 1987 - 1988
Ohio State University HospitalResidency, Internal Medicine, 1984 - 1987
University of Maryland School of MedicineClass of 1984
Certifications & Licensure
OH State Medical License 1998 - 2025
LA State Medical License 2021 - 2022
DC State Medical License 1992 - 1998
MD State Medical License 1987 - 1991
American Board of Internal Medicine Internal Medicine
Clinical Trials
- Efficacy and Safety of Sirolimus in LAM Start of enrollment: 2006 Dec 01
- Study Evaluating Fosfomycin/Tobramycin for Inhalation in Cystic Fibrosis Patients With Pseudomonas Aeruginosa Lung Infection Start of enrollment: 2008 Nov 01
- Safety & Efficacy Study of rAAV1-CB-hAAT for Alpha-1 Antitrypsin Deficiency Start of enrollment: 2010 Jun 01
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Publications & Presentations
PubMed
- Granulocyte-Macrophage Colony Stimulating Factor Receptor Contributes to Plexiform Neurofibroma Initiation.Jay Pundavela, Ashley Hall, Samantha Anne Dinglasan, Kwangmin Choi, Tilat A Rizvi
Cancers. 2025-03-06 - Circulating and Magnetic Resonance Imaging Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease.Jonathan R Dillman, Jean A Tkach, Joel G Fletcher, David H Bruining, Aiming Lu
Inflammatory Bowel Diseases. 2025-01-24 - Lung immune incompetency after mild peritoneal sepsis and its partial restoration by type 1 interferon: a mouse model study.Qiuming Meng, Fumiko Seto, Tokie Totsu, Tomoyuki Miyashita, Songfei Wu
Intensive Care Medicine Experimental. 2024-12-20
Journal Articles
- Inhaled Molgramostim Therapy in Autoimmune Pulmonary Alveolar ProteinosisBruce Trapnell, MD, New England Journal of Medicine
Press Mentions
Savara Announces New Data from Pivotal Phase 3 IMPALA-2 Trial of Molgramostim Nebulizer Solution (Molgramostim) in Patients with Autoimmune Pulmonary Alveolar Proteinosis (aPAP) Were Presented at the European Respiratory Society (ERS) Congress 2024September 8th, 2024- Savara Announces First Patient Dosed in Pivotal Phase 3 Autoimmune Pulmonary Alveolar Proteinosis (aPAP) TrialJune 30th, 2021
- New England Journal of MedicineSeptember 8th, 2020
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Grant Support
- Technology to understand genetic variant effects in contextUNIVERSITY OF WASHINGTON2019–2029
- Versatile, exponentially scalable methods for single cell molecular profilingUNIVERSITY OF WASHINGTON2019–2028
- New software tools for differential analysis of single-cell genomics perturbation experimentsUNIVERSITY OF WASHINGTON2023–2027
- Human gene transfer & macrophage cell transplantation therapy of hereditary PAP (hPAP)CINCINNATI CHILDRENS HOSP MED CTR2021–2026
- Human gene transfer & macrophage cell transplantation therapy of hereditary PAP (hPAP)CINCINNATI CHILDRENS HOSP MED CTR2021–2026
- Retrospective Autoimmune PAP Natural History and Patient-Reported Outcomes StudyCINCINNATI CHILDRENS HOSP MED CTR2022–2025
- Retrospective Autoimmune PAP Natural History and Patient-Reported Outcomes StudyCINCINNATI CHILDRENS HOSP MED CTR2022–2025
- Pathogenesis-Based Diagnostics and Pharmacotherapeutics for PAPCINCINNATI CHILDRENS HOSP MED CTR2007–2025
- Pathogenesis-Based Diagnostics and Pharmacotherapeutics for PAPCINCINNATI CHILDRENS HOSP MED CTR2007–2025
- Pathogenesis-Based Diagnostics and Pharmacotherapeutics for PAPCINCINNATI CHILDRENS HOSP MED CTR2007–2025
- Interdisciplinary Training in Genome SciencesUNIVERSITY OF WASHINGTON1995–2025
- Pulmonary Development and Disease Pathogenesis Training ProgramCINCINNATI CHILDRENS HOSP MED CTR1994–2025
- Pulmonary Development and Disease Pathogenesis Training ProgramCINCINNATI CHILDRENS HOSP MED CTR1994–2025
- Macrophage-Based Human Gene Therapy For Hereditary PAPNational Heart, Lung, And Blood Institute2011–2012
- Quantitative Chest Computed Tomography In Alpha-1-Antitrypsin DeficiencyNational Center For Research Resources2008
- Anticytokine Autoantibodies/Growth Factors In RARE Lung DiseasesNational Center For Research Resources2005–2008
- RARE Lung Disease Clinical Research NetworkNational Center For Research Resources2003–2008
- AAT Deficiency &Liver Diseases Caused By ProteinsNational Institute Of Diabetes And Digestive And Kidney Diseases2006
- Fourth Annual International Pulmonary Alveolar Proteinosis Research ConferenceNational Heart, Lung, And Blood Institute2006
- Regulation Of Alveolar Macrophage PhagocytosisNational Heart, Lung, And Blood Institute2003–2006
- Pulmonary Alveolar Proteinosis Research ConferenceNational Heart, Lung, And Blood Institute2005
- Conference--Pulmonary Alveolar Proteinosis ResearchNational Heart, Lung, And Blood Institute2004
- GM-CSF &Alveolar Macrophage Antiviral Lung DefenseNational Heart, Lung, And Blood Institute2001–2004
- Core--Viral VectorsNational Heart, Lung, And Blood Institute1997
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