Bruce G Haffty MD FASTRO FACR FASCO FARS

PubMed

• Lipogenic enzyme FASN promotes mutant p53 accumulation and gain-of-function through palmitoylation.
  Juan Liu, Yiyun Shen, Jie Liu, Dandan Xu, Chun-Yuan Chang
  Nature Communications. 2025-02-19
• If We Build It, Why They Do Not Come? An American College of Surgeons National Quality Improvement Collaborative to Understand Barriers to Completion of Cancer Treatment.
  Lauren M Janczewski, Anthony D Yang, Eileen Reilly, Kelley Chan, Tashae Coates
  JCO Oncology Practice. 2025-02-10
• First Results of the Primary Outcome of a Phase 2 Prospective Clinical Trial to Assess the Feasibility of Preoperative Radiation Boost in Patients With Breast Cancer.
  Zeinab Abou Yehia, Zohaib Sherwani, Molly Chakraborty, Nisha Ohri, Alison Grann
  International Journal of Radiation Oncology, Biology, Physics. 2025-02-01

Journal Articles

• Prevalence of Surface Contamination with SARS-CoV-2 in a Radiation Oncology Clinic  
  Mutlay Sayan, Ronald D Ennis, Bruce G Haffty, JAMA Oncology
• SREBP1, Targeted by miR-18a-5p, Modulates Epithelial-Mesenchymal Transition in Breast Cancer via Forming a Co-Repressor Complex with Snail and HDAC1/2  
  Bruce Haffty, MD, Nature
• The Feasibility of Breast-Conserving Surgery for Multiple Ipsilateral Breast Cancer: An Initial Report from ACOSOG Z11102 (Alliance) Trial  
  Kelly K Hunt, Armando Giuliano, Judy C Boughey, Laurie Cuttino, Kari M Rosenkranz, Bruce Haffty, Annals of Surgical Oncology
• Nation-Scale Adoption of Shorter Breast Radiation Therapy Schedules Can Increase Survival in Resource Constrained Economies: Results From a Markov Chain Analysis  
  Khan AJ, Rafique R, Zafar W, Shah C, Haffty BG, Vicini F, Jamshed A, Zhao Y, Int J Radiat Oncol Biol Phys, 1/1/2017
• Comparison of Mammographic Changes Across Three Different Fractionation Schedules for Early-Stage Breast Cancer  
  Tian S, Paster LF, Kim S, Kirstein L, Haffty BG, Ferro A, Amorosa J, Goyal S, Int J Radiat Oncol Biol Phys, 1/4/2016
• Glutaminase 2 is a novel negative regulator of small GTPase Rac1 and mediates p53 function in suppressing metastasis  
  Zhang C, Liu J, Zhao Y, Yue X, Zhu Y, Wang X, Wu H, Blanco F, Li S, Bhanot G, Haffty BG, Hu W, Feng Z, Elife, 1/1/2016
• Significance of tumor biology on local control in breast cancer  
  Goyal S, Haffty BG, Oncology, 1/1/2014
• National residency matching program results for radiation oncology: 2012 update  
  Aneja S, Wilson LD, Haffty BG, Yu JB, 1/1/2013
• Hypofractionated breast radiation: preferred standard of care?  
  Haffty BG, Buchholz TA, Lancet Oncol, 1/1/2013
• External-beam accelerated partial-breast irradiation: exploring the limits of tolerability  
  Jagsi R, Haffty BG, J Clin Oncol, 1/1/2013
• Inhibition of filamin-a reduces cancer metastatic potential  
  Jiang X, Yue J, Lu H, Campbell N, Yang Q, Lan S, Haffty BG, Yuan C, Shen Z, Int J Biol Sci, 1/1/2013
• A profile of academic training program directors and chairs in radiation oncology  
  Wilson LD, Haffty BG, Smith BD, Int J Radiat Oncol Biol Phys, 1/1/2013
• Are breast cancer subtypes prognostic for nodal involvement and associated with clinicopathologic features at presentation in early-stage breast cancer?  
  Jones T, Neboori H, Wu H, Yang Q, Haffty BG, Evans S, Higgins S, Moran MS, Ann Surg Oncol, 1/1/2013
• Role of excision repair cross-complementation 1 expression as a prognostic marker for response to radiotherapy in early-stage laryngeal cancer  
  Johung K, Rewari A, Wu H, Judson B, Contessa JN, Haffty BG, Decker RH, Head Neck, 1/28/2012
• Evaluation of Current Consensus Statement Recommendations for Accelerated Partial Breast Irradiation: A Pooled Analysis of William Beaumont Hospital and American Socie...  
  Wilkinson JB, Beitsch PD, Shah C, Arthur D, Haffty BG, Wazer DE, Keisch M, Shaitelman SF, Lyden M, Chen PY, Vicini FA, Int J Radiat Oncol Biol Phys, 1/22/2012
• Local Control, Toxicity, and Cosmesis in Women >70 Years Enrolled in the American Society of Breast Surgeons Accelerated Partial Breast Irradiation Registry Trial  
  Khan AJ, Vicini FA, Beitsch P, Goyal S, Kuerer HM, Keisch M, Quiet C, Zannis V, Keleher A, Snyder H, Gittleman M, Whitworth P Jr, Fine R, Lyden M, Haffty BG, Int J Radiat Oncol Biol Phys, 1/21/2012
• Outcome after ipsilateral breast tumor recurrence in patients who receive accelerated partial breast irradiation  
  Shah C, Vicini F, Keisch M, Kuerer H, Beitsch P, Haffty B, Lyden M, Cancer, 1/17/2012
• Using respiratory motion to guide planning target volume margins for external beam partial breast irradiation  
  Kim LH, Goyal S, Haffty BG, Taunk NK, Yue NJ, Int J Radiat Oncol Biol Phys, 1/15/2012
• Characteristics of double heterozygosity for BRCA1 and BRCA2 germline mutations in Korean breast cancer patients  
  Noh JM, Choi DH, Nam SJ, Lee JE, Kim JW, Kim SW, Kang E, Lee MH, Ahn SH, Kim KS, Park SK, Haffty BG; Korea Breast Cancer Study Group, Breast Cancer Res Treat, 1/1/2012
• ACR Appropriateness Criteria® Local-regional Recurrence (LR) and Salvage Surgery: Breast Cancer  
  Halyard MY, Wasif N, Harris EE, Arthur DW, Bailey L, Bellon JR, Carey L, Goyal S, Horst KC, Moran MS, Macdonald SM, Haffty BG; Expert Panel on Radiation Oncology–Breast, Am J Clin Oncol, 1/1/2012
• Quantitative in situ measurement of estrogen receptor mRNA predicts response to tamoxifen  
  Bordeaux JM, Cheng H, Welsh AW, Haffty BG, Lannin DR, Wu X, Su N, Ma XJ, Luo Y, Rimm DL, PLoS One, 1/1/2012
• National Residency Matching Program (NRMP) results for radiation oncology: 2011 update  
  Aneja S, Wilson LD, Haffty BG, Yu JB, Int J Radiat Oncol Biol Phys, 1/1/2012
• Characteristics and spectrum of BRCA1 and BRCA2 mutations in 3,922 Korean patients with breast and ovarian cancer  
  Kim H, Cho DY, Choi DH, Choi SY, Shin I, Park W, Huh SJ, Han SH, Lee MH, Ahn SH, Son BH, Kim SW; Korean Breast Cancer Study Group, Haffty BG, Breast Cancer Res Treat, 1/1/2012
• Tumor bed control with balloon-based accelerated partial breast irradiation: incidence of true recurrences versus elsewhere failures in the American Society of Breast ...  
  Beitsch PD, Wilkinson JB, Vicini FA, Haffty B, Fine R, Whitworth P, Kuerer H, Zannis V, Lyden M, Ann Surg Oncol, 1/1/2012
• Testin is a tumor suppressor and prognostic marker in breast cancer  
  Zhu J, Li X, Kong X, Moran MS, Su P, Haffty BG, Yang Q, Cancer Sci, 1/1/2012
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Books/Book Chapters

• Principles and Practice of Radiation Oncology 
  Chapter: Breast Cancer: Locally Advanced and Recurrent Disease, Postmastectomy Radiation, Systemic Therapies 
  Buchholz TA, Wazer DE, Haffty BGEditors: Halperin, Perez, Brady.Lippincott Williams & Wilkins, 6th2013
• Principles and Practice of Radiation Oncology 
  Chapter: Breast Cancer: Early Stage 
  Goyal S, Buchholz TA, Haffty BGEditors: Halperin, Perez, Brady.Lippincott Williams & Wilkins, 6th2013
• Head and Neck Cancer – A Multidisciplinary Approach 
  Chapter: Prognostic Factors in Patients with Head and Neck Cancer 
  Kim S, Smith BD, Haffty BGLippincott Williams & Wilkins, 4th2013
• Year Book of Oncology 
  Haffty, BG , et al2011
• Kuerer's Breast Surgical Oncology 
  Editors: Kuerer, ed, Haffty BG, section editor (Radiation Oncology).McGraw-Hill2010
• Diseases of the Breast 
  Chapter: Postmastectomy Radiation 
  Khan A, Haffty BGEditors: Harris, Lippman, Morrow, Osborne.Lippincott, Williams & Wilkins, 4th2010
• Breast Surgery: Office Management and Surgical Techniques 
  Chapter: Controversies in the Conservative Management of Breast Cancer 
  Haffty BGEditors: Scott-Conner and Dirbas.Springer2010
• Kuerer's Breast Surgical Oncology 
  Chapter: Conceptual Basis and Principles of Radiation Oncology 
  Haffty BG, Narra V, Yue NJEditors: Kuerer.McGraw-Hill2010
• Encyclopedia of Radiation Oncology 
  Chapter: Molecular Markers in Clinical Radiation Oncology 
  Haffty BGEditors: Brady.Springer-Verlag2010
• Emerging Cancer Therapeutics 
  Chapter: Advances in Radiotherapy for Breast Cancer 
  Goyal S, Khan AJ, Haffty BGDemos Medical2010
• Handbook of Radiation Oncology 
  Chapter: Wilson LD EDS 
  Haffty BGJones and Bartlett2009
• Handbook of Radiation Oncology 
  Chapter: Radiation Therapy in Early Stage Breast Cancer 
  Haffty BGEditors: Haffty BG, Wilson LD.2009
• Principles and Practice of Radiation Oncology 
  Chapter: Management of Advance Breast Cancer 
  Buchholz TA, Haffty BGEditors: Halperin, Perez, Brady.Lippincott, Williams & Wilkins, 5th2008
• Breast Cancer Management and Molecular Medicine: Towards Tailored Approaches 
  Chapter: Breast cancer management in the Era of molecular Medicine: Tailored Radiotherapy-Clinical and Biological Aspects 
  Haffty BGEditors: Piccart M, Wood WC, Hung MC, Solin LJ Caroso F.Springer2006
• Head and Neck Cancer: A Multidisciplinary Approach 
  Chapter: Prognostic Factors in Head and Neck Cancer 
  Smith BD and Haffty BGEditors: Harrison LB, Session RB and Hong WK.Lippincott Williams & Wilkins, 2nd2002
• Breast Cancer Management. Application of Evidence to Patient Care 
  Chapter: Radiation Therapy in the Management of Breast Cancer 
  Haffty BGEditors: Nabholtz, Tonkin, Aapro, Buzdar.Martin Dunitz2000
• Cancer Management: A Multidisciplinary Approach 
  Chapter: Stage III and IV Breast Cancer 
  Jardines L, Haffty BG, Theriault REditors: Pazdur, Coia, Hoskins, Wagman.3rd1999
• Cancer Management: A Multidisciplinary Approach 
  Chapter: Stage II Breast Cancer 
  Jardines L, Haffty BG, Theriault REditors: Pazdur, Coia, Hoskins, Wagman.3rd1999
• Expert Consultations in Breast Cancer 
  Editors: Hait WE, August DA, Haffty BG.Marcel Dekker1999
• Expert Consultations in Breast Cancer 
  Chapter: Radiation therapy in the management of breast cancer 
  Page 47 - 63Higgins SA and Haffty BGEditors: Hait, August, Haffty.Marcel Dekker1999
• Expert Consultations in Breast Cancer 
  Chapter: Case Discussion-Aggressive chest wall recurrence following mastectomy 
  Page 306 - 308Obedian E and Haffty BGEditors: Hait, August, Haffty.Marcel Dekker1999
• Expert Consultations in Breast Cancer 
  Chapter: Case Discussion -Axillary recurrence of a breast cancer following axillary dissection 
  Page 316 - 318Obedian E and Haffty BGEditors: Hait, August, Haffty.Marcel Dekker1999
• Expert Consultations in Breast Cancer 
  Chapter: Case Discussion-Axillary recurrence of a breast cancer following lumpectomy 
  Page 318 - 321Obedian E and Haffty BGEditors: Hait, August, Haffty.Marcel Dekker1999
• Expert Consultations in Breast Cancer 
  Chapter: Case Discussion-Sequencing chemotherapy and radiation therapy in early stage breast cancer 
  Page 239 - 243Mehta K and Haffty BGEditors: Hait, August, Haffty.Marcel Dekker1999
• Expert Consultations in Breast Cancer 
  Chapter: Case Discussion-Post mastectomy radiation therapy 
  Page 254 - 57Mehta K and Haffty BGEditors: Hait, August, Haffty.Marcel Dekker1999
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Abstracts/Posters

• Tracking the dynamic seroma cavity using fiducial markers in patients treated with accelerated partial breast irradiation using 3D conformal radiotherapy
  Yue NJ, Haffty BG, Kearney T, Kirstein L, Chen S, Goyal S, Medical Physics, 1/1/2013
• TH-C-WAB-07: Optimization of Heart Block in the Left-Sided Whole Breast Irradiation
  Yue N, Goyal S, Park J, Jones S, Xu X, Khan A, Haffty BG, Chen T, Medical Physics, 1/1/2013
• SU-E-T-469: Dosimetric Impact of Whole Breast Treatment Planning with Tissue Heterogeneity Correction
  Nishioka S, Kim L, Goyal S, Khan A, Haffty BG, Yue NJ, Medical Physics, 1/1/2013
• SU-E-J-149: Heart Protection in Proton Therapy Using 4D Motion Analysis Based On Registration Between SENSE MRI and 4DCT
  Chen T, Zou W, Zhang M, Yue NJ, Haffty BG, Khan A, Goyal S, Medical Physics, 1/1/2013
• Variability of Tumor Motion in 4DCT: The Effects of Abdominal Compression on Lung Tumor Displacement
  Rosenberg S, Jabbour SK, Yue NJ, Rasheed A, Haffty BG, Goyal S, Khan AJ, Int J Radiation Oncol Biol Phys, 1/1/2012
• Basal Subtype, as Approximated by Triple Negative Phenotype, is Associated With Locoregional Recurrence in a Case-control Study of Women With 0-3 Positive Lymph Nodes ...
  Khan AJ, Milgrom S, Barnard N, Higgins SA, Moran MS, Kim S, Goyal S, Alfaraj F, Haffty BG, Int J Radiation Oncol Biol Phys, 1/1/2012
• TU-G-BRC-06: Patterns of Intra-Fractional Motion and Uncertainties of Treatment Setup Reference Systems in Accelerated Partial Breast Irradiation of Right- and Left-Si...
  Yue, N and Goyal, S and Braun, K and Khan, A and Haffty, B, Medical Physics, 1/1/2011
• The Prognostic Value of MDM2, MDM4 (MDMX), and p53 in Early Stage Breast Cancer Treated with Breast Conserving Surgery and Radiotherapy
  Neboori, H. and Wu, H. and Schiff, D. and Goyal, S. and Moran, M. and Yang, J. and Hirshfield, K.M. and Haffty, BG, Int J Radiation Oncol Biol Phys, 1/1/2011
• The American Society of Breast Surgery MammoSite Registry: Factors Associated with Optimal Long-term Cosmetic Results
  Beitsch, P.D. and Vicini, F. and Keisch, M. and Goyal, S. and Khan, A. and Lyden, M. and Sha, C. and Haffty, B., Int J Radiation Oncol Biol Phys, 1/1/2011
• SU-E-T-639: Fast Beam Allocation Algorithm for Gamma Knife Based SRS Planning
  Chen, T and Danish, S and Cohler, A and Goyal, S and Khan, A and Haffty, B and Yue, N, Medical Physics, 1/1/2011
• SU-E-T-238: OnedosePlus MOSFET Dosimeter Performance in Tangential Field in Vivo Dosimtery
  Chen, T and Levinson, L and Zhang, M and Goyal, S and Haffty, B and Yue, N, Medical Physics, 1/1/2011
• Optimal PTV Margin in Patients with Fiducial Markers Treated with Accelerated Partial Breast Irradiation (APBI) using 3D-CRT: Final Results of CINJ 040801
  Goyal, S. and Braun, K. and Haffty, BG and Kearney, T. and Azu, M. and Yue, N.J., Int J Radiation Oncol Biol Phys, 1/1/2011
• Early Results of a Novel Hypofractionated Schedule for Adjuvant Radiation Therapy in Early-stage Breast Cancer
  Nelson, C. and Goyal, S. and Ahlawat, S. and Haffty, B. and Khan, A., Int J Radiation Oncol Biol Phys, 1/1/2011
• DEAD box 1 (DDX1) Expression Predicts for Local Control and Overall Survival in Early-stage, Node-negative Breast Cancer Treated with Breast Conserving Surgery and Rad...
  Taunk NK, Goyal S, Wu H, Moran MS, Chen S, Haffty BG, Int J Radiation Oncol Biol Phys, 1/1/2011
• Abstract 2489: Targeting pro-survival BCL-2 family members increases radiation sensitivity in breast cancer cells
  Wu H, Schiff DS, Goyal S, Neboori HJR, Haffty BG, Cancer Research, 1/1/2011
• Low Risk Ductal Carcinoma In Situ (DCIS) Treated with Breast Conserving Surgery & Accelerated Partial Breast Irradation (APBI): Comparison of the Mammosite Registry Tr...
  Goyal, S. and Vicini, F. and Beitsch, P. and Keisch, M. and Jeruss, J. and Lyden, M. and Haffty, B., Cancer Research, 1/1/2010
• TH-C-201C-05: A Laplacian Surface Deformation and Optimization Based 3D Registration Algorithm for Image Guided Prostate Radiotherapy
  Zhou, J and Kim, S and Jabbour, S and Goyal, S and Haffty, B and Zhang, S and Chen, T and Metaxas, D and Yue, N, Medical Physics, 1/1/2010
• Targeting Prosurvival Bcl-2 Family Members Increases Radiation Sensitivity in Breast Cancer Cells
  Wu, H. and Schiff, D.S. and Goyal, S. and Haffty, BG, Int J Radiation Oncol Biol Phys, 1/1/2010
• Tamoxifen Confers a Limited Benefit in Older Women with Early Stage Breast Cancer
  Khan, A.J. and Parikh, R.R. and Goyal, S. and Moran, M.S. and Haffty, BG, Int J Radiation Oncol Biol Phys, 1/1/2010
• SU-EE-A3-05: Real Time Tumor Motion Monitoring during IGRT Based on Manifold Learning and Dynamic Registration between 4DCT and Fluoroscopy
  Chen, T and Jabbour, S and Goyal, S and Zhou, J and Haffty, B and Yue, N, Medical Physics, 1/1/2010
• Riluzole Increases Ionizing Radiation Related Cellular Toxicity in Metabotropic Glutamate Receptor 1 Positive Human Breast Cancer Cells
  Ahlawat, S. and Khan, A.J. and Goyal, S. and Schiff, D. and Wu, H. and Moran, M. and Haffty, BG, Int J Radiation Oncol Biol Phys, 1/1/2010
• Racial Disparities in Treatment Outcomes for African American Women with Ductal Carcinoma In Situ Receiving Whole Breast Irradiation following Breast Conserving Surgery
  Nelson, C. and Goyal, S. and Moran, M. and Motwani, S. and Haffty, B., Int J Radiation Oncol Biol Phys, 1/1/2010
• Placement and Visualization of Surgical Clips in the Lumpectomy Cavity of Patients with Stage 0, I, and II Breast Cancer Treated with Breast Conserving Surgery and Rad...
  Patel, U. and Haffty, BG and Azu, M. and Kearney, T. and Yue, N.J. and Goyal, S., Int J Radiation Oncol Biol Phys, 1/1/2010
• Improvement in Interobserver Accuracy in Delineation of the Lumpectomy Cavity Using Fiducial Markers
  Shaikh, Talha and Chen, Ting and Khan, Atif and Yue, Ning J. and Kearney, Thomas and Cohler, Alan and Haffty, Bruce G. and Goyal, Sharad, Int J Radiation Oncol Biol Phys, 1/1/2010
• Extent of Axillary Dissection Predicts Survival in pN0 Early Stage Breast Cancer
  Parikh, R.R. and Khan, A.J. and Goyal, S. and Ahlawat, S. and Moran, M.S. and Haffty, BG, Int J Radiation Oncol Biol Phys, 1/1/2010
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Lectures

• Beyond whole breast irradiation 
  Dallas, TX - 1/1/2017
• Hypofractionation and partial breast irradiation 
  Santiago, Chile - 1/1/2017
• Evolution of Regional Nodal Treatment in Breast Cancer 
  Moffitt Cancer Center, Tampa, FL - 1/1/2017
• Regional Nodal Management of Breast Cancer 
  Multiple locations, 2012, 2013, 2014, 2015, 2016 - 1/1/2016
• Clinical Trials 
  San Diego, CA - 1/1/2016
• Evolution of the Regional Nodal Management of Breast Cancer 
  Manhasset, NY - 1/30/2015
• Local-Regional Management of Triple Negative Breast Cancer 
  Pittsburgh, PA - 1/24/2015
• Regional Nodal Irradiation in Breast Cancer 
  Pittsburgh, PA - 1/24/2015
• New Developments in the Regional Nodal Management of Breast Cancer 
  New York, NY - 1/7/2015
• Phase III Clinical Trials 
  University of Pennsylvania, Philadelphia, PA - 1/1/2015
• Management of Oligometastasis 
  Barcelona - 1/1/2015
• Breast Radiation Oncology: United States Perspective 
  Kyoto, Japan - 1/1/2015
• Stephen Leibel Memorial Lecture: Therapeutic Gains from Technologic Advances in Radiation Oncology 
  Washington, DC - 1/1/2015
• Choosing the Best Treatment for Early Stage Breast Cancer 
  Washington, DC - 1/1/2015
• The Evolution of the Regional Nodal Management of Breast Cancer: Past, Present and Future 
  Nanjing City, Jiangsu Province, People’s Republic of China - 1/23/2014
• Targeting Triple Negative Breast Cancers to Improve Outcomes with Radiation 
  Las Vegas, NV - 1/20/2014
• Evolving Role of Regional Nodal Irradiation 
  Eastern Maine Medical Center, Bangor, ME - 1/16/2014
• Revisiting Regional Nodal Management of Breast Cancer 
  Amelia Island, FL - 1/13/2014
• Radiation Issues for Molecular Subtypes of Breast Cancer 
  Amelia Island, FL - 1/13/2014
• Radiation After Neoadjuvant Systemic Therapy 
  Amelia Island, FL - 1/13/2014
• Locoregional Management for Triple Negative Breast Cancer 
  Vienna, Austria - 1/7/2014
• Can XRT Improve Survival in Early-Stage Breast Cancer? – No 
  Las Vegas, NV - 1/2/2014
• Thirty Years in Breast Radiation Oncology: Back to the Future 
  San Francisco, CA - 1/1/2014
• Molecular Genetic Factors in Local-Regional Management of Breast Cancer 
  MD Anderson Cancer Center Orlando, Orlando, FL - 1/30/2013
• Local-Regional Management of Breast Cancer 
  Fortaleza, Brazil - 1/29/2013
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Other

• Applications of Ear Densitography to Cardiovascular Hemodynamics (M.D. Thesis) 
  Haffty BG, Yale University
  1/1/1984
• Electrical Impedance Assessment of Cardiopulmonary Hemodynamics (M.S. Thesis) 
  Haffty BG, Worcester Polytechnic Institute
  1/1/1976
• Investigations into the Clinical Implementation of Impedance Plethysmography for Arterial Diagnosis 
  Haffty BG, et al, Final Technical Report, Grant #EPP75-08986, National Science Foundation
  1/1/1975
• Development of a non-invasive arterial function test 
  Penny BP, Haffty BG et al, Final Technical Report, National Science Foundation
  1/1/1974
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