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Office
4701 Ogletown Stanton Rd
Helen F Graham Cancer Center
Newark, DE 19713Phone+1 302-623-4205Fax+1 215-955-2340
Education & Training
- National Institutes of Health Clinical CenterFellowship, Hematology and Medical Oncology, 1982 - 1984
- Mayo Clinic College of Medicine and Science (Rochester)Fellowship, Hematology and Medical Oncology, 1980 - 1982
- Mayo Clinic College of Medicine and Science (Rochester)Residency, Internal Medicine, 1977 - 1980
- University of Minnesota Medical SchoolClass of 1976
Certifications & Licensure
- DC State Medical License 1983 - Present
- DE State Medical License 2007 - 2025
- PA State Medical License 1998 - 2024
- MD State Medical License 1983 - 2020
- IA State Medical License 1996 - 2000
- MN State Medical License 1978 - 1987
- TX State Medical License 1985 - 1987
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Medical Oncology
Clinical Trials
- Rosuvastatin in Treating Patients With Stage I or Stage II Colon Cancer That Was Removed By Surgery Start of enrollment: 2010 Mar 01
Publications & Presentations
PubMed
- 49 citationsIncreased Expression of the Retinoblastoma Gene in Human Colorectal Carcinomas Relative to Normal Colonic MucosaRajalakshmi Gope, Mark A. Christensen, Alan G. Thorson, Henry T. Lynch, Thomas C. Smyrk
Journal of the National Cancer Institute. 1990-02-21 - 18 citationsDoes the human retinoblastoma gene have a role in colon cancerD. M. Wildrick, B. M. Boman
Molecular Carcinogenesis. 1994-05-01 - 803 citationsAldehyde dehydrogenase 1 is a marker for normal and malignant human colonic stem cells (SC) and tracks SC overpopulation during colon tumorigenesis.Emina Huang, Mark Hynes, Tao Zhang, Christophe Ginestier, Gabriela Dontu
Cancer Research. 2009-04-15
Journal Articles
- The Anti-Cancer Effect of Retinoic Acid Signaling in CRC Occurs via Decreased Growth of ALDH+ Colon Cancer Stem Cells and Increased Differentiation of Stem CellsBruce Boman, MD, Oncotarget
Press Mentions
- ChristianaCare Research May Result in 'More Precise' Advanced Colorectal Cancer TreatmentApril 5th, 2023
- Scientists Discover Second Key Pathway in Colon Cancer Stem Cell GrowthOctober 29th, 2020
- Key Signaling Pathway Could Lead to New Targets in Colorectal CancerDecember 20th, 2018
Grant Support
- AP4 Center For Studies On Hereditary Colorectal CancerNational Cancer Institute2004
- Proteomic Analyses For GI Stem Cell Markers &MechanismsNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2004
- Markers For Stem Cell-Like Colonic Crypt Base CellsNational Institute Of Diabetes And Digestive And Kidney Diseases2003–2004
- Characterizing Murine GI Stem Cells: New Molecular ToolsNational Cancer Institute2003–2004
- Core--Gastrointestinal CancerNational Cancer Institute2001–2002
- Approach For Colon Cancer Therapy Using APC PeptidesNational Cancer Institute1996–1998
Professional Memberships
- Member
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