Dr. Debosch is on Doximity
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Office
705 Riley Hospital Dr,
Indianapolis, IN 46202Phone+1 317-944-2060
Education & Training
- Washington University/B-JH/SLCH ConsortiumFellowship, Pediatric Gastroenterology, 2010 - 2013
- Washington University/B-JH/SLCH ConsortiumResidency, Pediatrics, 2008 - 2010
- Washington University in St. LouisPh.D., Molecular Cell Biology, 2001 - 2008
- Washington University in St. Louis School of MedicineClass of 2008
- University of Michigan Medical SchoolBS, Cellular & Molecular Biology, Summa Cum Laude, 1997 - 2001
Awards, Honors, & Recognition
- Robert Wood Johnson Foundation Scholar Amos Medical Faculty Development Program, 2016
- Recognition Award St. Louis Children's Hosptial, 2015
- Scholars Award in Liver Disease American Gastroenterological Association / Gilead Sciences Research, 2015
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Publications & Presentations
PubMed
- Protocol to evaluate fasting metabolism and its relationship to the core circadian clock in mice.Jiameng Sun, Brian J DeBosch
STAR Protocols. 2025-03-21 - Beyond Scratching the Surface: A Nonpruritogenic Novel Bile Acid Derivative That Ameliorates Cholestatic- and Diet-Induced Liver Injury.Rebecca Haeusler, Brian J Debosch
Gastroenterology. 2025-03-07 - A New Tool to Study the DREADDed Peripheral Nervous System.Amber L Alhadeff, Brian J DeBosch
Gastroenterology. 2025-02-01
Abstracts/Posters
- Transmissible Protection From Fructose Induced Hepatic Steatosis Using Microbiota From Mice With Defective Intestinal Chylomicron ProductionYan Xie, Hitoshi Matsumoto, Susan Kennedy, Brian J. DeBosch, Kelle H. Moley, Yanjiao Zhou, Phillip I. Tarr, Nicholas O. Davidson, American Gastroenterological Association Digestive Diseases Week, San Diego, CA, 1/1/2016
- GLUT8 (SLC2A8) Is a Mammalian Trehalose Transporter Required for Trehalose-Induced Autophagy.Brian DeBosch, Allyson L Mayer, Monique R Heitmeier, Paul Hruz and Cassandra B Higgins., American Gastroenterological Association Digestive Diseases Week, San Diego, CA, 1/1/2016
- Trehalose inhibits SLC2A Proteins to induce autophagy and prevent hepatic steatosis.BJ DeBosch, M Heitmeier, AL Mayer, CB Higgins, M Chi, K Yarasheski, J Crowley, Z Chen, BN Finck, PW Hruz, KH Moley., Midwest DDRCC Symposium, Washington University, St. Louis, MO, 1/1/2015
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Lectures
- Trehalose, Cellular Action and Therapeutic Possibilities1/1/2016
- Treatment for Pediatric NAFLD: Sweet new therapies are coming through the portal!Washington University School of Medicine - 1/1/2015
- Spontaneous, Early-Onset Metabolic Syndrome in Mice Lacking the Enterocyte Urate Transporter1/1/2014
Press Mentions
- Study Reveals New Insights into Urea Cycle's Role in Fatty Liver DiseaseAugust 15th, 2024
- New Research Explores the Urea Cycle’s Strong Connection to Fatty Liver DiseaseAugust 14th, 2024
- Glenn Foundation for Medical Research and AFAR Announce 2019 Grants for Junior FacultyDecember 23rd, 2019
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Grant Support
- Leveraging arginase biology against metabolic diseaseWASHINGTON UNIVERSITY2023–2027
- Leveraging glucose transport and the adaptive fasting response to modulate hepatic metabolismINDIANA UNIVERSITY INDIANAPOLIS2021–2025
- Leveraging glucose transport and the adaptive fasting response to modulate hepatic metabolismINDIANA UNIVERSITY INDIANAPOLIS2021–2025
- Treating secondary cardiomyopathies by mimicking the adaptive hepatic glucose fasting responseWASHINGTON UNIVERSITY2020–2025
Professional Memberships
- American Society for Clinical Investigation (ASCI)Member
- Society for Pediatric ResearchMember
- Member
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