Bonnie Ky MD

PubMed

• Risk-guided cardioprotection with carvedilol in patients with breast cancer (CCT guide): a phase 1 randomized clinical trial.
  Wonyoung Jung, Rebecca A Hubbard, Amanda M Smith, Kyunga Ko, Anran Huang
  Breast Cancer Research and Treatment. 2025-04-02
• 1 citations
  Cardiac Effects of Modern Breast Radiation Therapy in Patients Receiving Systemic Cancer Therapy.
  Eva Berlin, Kyunga Ko, Lin Ma, Ian Messing, Casey Hollawell
  JACC. Cardiooncology. 2025-02-27
• Socioeconomic status and left ventricular ejection fraction decline in breast cancer survivors following receipt of doxorubicin (PREVENT WF-98213).
  Arnethea L Sutton, Nathaniel S O'Connell, Alexander R Lucas, Kristine C Olson, Kerryn W Reding
  Cardio-Oncology. 2025-02-05

Journal Articles

• Diastolic Dysfunction in Tetralogy of Fallot: Comparison of Echocardiography with Catheterization  
  Bonnie Ky, Elizabeth Goldmuntz, Echocardiography
• Original Research Abnormalities in 3-Dimensional Left Ventricular Mechanics with Anthracycline Chemotherapy Are Associated with Systolic and Diastolic Dysfunction  
  Kathleen W Zhang, Gaurav Gulati, Hari K Narayan, Jenica Upshaw, W Gregory Hundley, Vivek Narayan, Bonnie Ky, ScienceDirect
• Dose-Response Effects of Aerobic Exercise among Colon Cancer Survivors: A Randomized Phase II Trial  
  Brown JC, Troxel AB, Ky B, Damjanov N, Zemel BS, Rickels MR, Rhim AD, Rustgi AK, Courneya KS, Schmitz KH, Clinical Colorectal Cancer, 1/17/2017
• Prospective Evaluation of Sunitinib-Induced Cardiotoxicity in Patients with Metastatic Renal Cell Carcinoma  
  Narayan V, Keefe S, Haas N, Wang L, Puzanov I, Putt M, Catino A, Fang J, Agarwal N, Hyman D, Smith AM, Finkelman BS, Nayan HK, Ewer S, ElAmm C, Lenihan D, Ky B, Clinical Cancer Research, 1/14/2017
• Prevention and Monitoring of Cardiac Dysfunction in Survivors of Adult Cancers: American Society of Clinical Oncology Clinical Practice Guideline  
  Armenian SH, Lacchetti C, Barac A, Carver J, Constine LS, Denduluri N, Dent S, Douglas PS, Durand JB, Ewer M, Fabian C, Hudson M, Jessup M, Jones LW, Ky B, Mayer EL, M..., Journal of Clinical Oncology, 1/10/2017
• Arginine-Nitric Oxide Metabolites and Cardiac Dysfunction in Patients With Breast Cancer  
  Finkelman B, Putt M, Wang T, Wang L,Narayan H, Domchek S, DeMichele A, Fox K, Matro J, Shah P, Clark A, Bradbury A, Narayan V, Carver JR, Tang W, Ky B, Journal of the American College of Cardiology, 1/1/2017
• Cardiac mechanics and dysfunction with anthracyclines in the community: results from the PREDICT study  
  Narayan HK, Wei W, Feng Z, Lenihan D, Plappert T, Englefield V, Fisch M, Ky B, Open Heart, 1/1/2017
• A Novel Positron Emission Tomography (PET) Approach to Monitor Cardiac Metabolic Pathway Remodeling in Response to Sunitinib Malate  
  O'Farrell ACO, Evans R, Silvola JMU, Miller IS, Conroy E, Hector S, Cary M et al, Plos One, 1/1/2017
• Anastrozole in Pulmonary Arterial Hypertension (AIPH): A Randomized, Double-Blind Placebo-Controlled Trial  
  Kawut SM, Archer-Chicko CL, DiMichele A, Fritz JS, Klinger JR, Ky B, Palevsky HI et al, American Journal of Respiratory and Critical Care Medicine, 1/1/2017
• Prognostic Value of Soluble Suppression of Tumorigenicity-2 in Chronic Heart Failure: A Meta-Analysis  
  Aimo A, Vergaro G, Passino C, Ripoli A, Ky B, Miller WL, Bayes-Genis A, Anand I, Januzzi JL, Emdin M, JACC Heart Failure, 1/1/2017
• Genome-wide association and pathway analysis of left ventricular function after anthracycline exposure in adults  
  Wells QS, Veatch OJ, Fessel JP, Joon AY, Mosley JD, Held EP, Lindsay CS, Shaffer CM, Weeke P, Van Driest SL, Karnes JH, Blair MA, Lagrone LW, Su YR, Bowton EA, Feng Z,..., Pharmacogenetics and Genomics, 1/1/2017
• Dose-response Effects of Aerobic Exercise on Body Composition Among Colon Cancer Survivors: A Randomised Controlled Trial  
  Brown JC, Zemel BS, Troxel AB, Rickels MR, Damjanov N, Ky B, Rhim AD, Rustgi AK, Courneya KS, Schmitz KH, British Journal of Cancer, 1/1/2017
• Contrast Echocardiography Provides the Greatest Impact in Patients with Reduced Ejection Fraction  
  Zhao H, O'Quinn R, Ambrose M, Jagasia D, Ky B, Wald J, Ferrari V, Kirkpatrick J, and Han Y, Journal of the American Society of Echocardiography, 1/1/2017
• Vascular complications of cancer and cancer therapy  
  Lyman G, Catino A, Ky B, CardioOncolog, 1/1/2017
• Cardiovascular Disease in Survivors of Childhood Cancer: Insights into Epidemiology, Pathophysiology, and Prevention  
  Armenian SH, Armstrong GT, Aune G, Chow EJ, Ehrhardt MJ, Ky B, Moslehi J, Mulrooney DA, Nathan PC, Ryan TD, van der Pal HJ, van Dalen EC, Kremer LC, Journal of Clinical Oncology, 1/1/2017
• Carfilzomib-Associated Cardiovascular Adverse Events: A Systematic Review and Meta-Analysis  
  Waxman AJ, Clasen S, Hwang WT, Garfall A, Vogl DT, Carver J, O'Quinn R, Cohen AD, Stadtmauer E, Ky B, Weiss BM, JAMA Oncology, 1/1/2017
• Echocardiography Core Lab Reproducibility of Cardiac Safety Assessments in Cardio-Oncology  
  Khouri MG, Ky B, Dunn G, Plappert T, Englefield V, Rabineau D, Yow E, Barnhart HX, St. John Sutton M, Douglas PS:, Journal of the American Society of Echocardiography, 1/1/2017
• In Depth, Reproducible Analysis of Human Plasma Using IgY 14 and SuperMix Immunodepletion  
  Beer LA, Ky B, Barnhart KT, Speicher DW, Methods Mol Biol, 1/1/2017
• Dose-response effects of exercise on insulin among colon cancer survivors  
  Brown J, Rickels M, Troxel A, Zemel B, Damjanov N, Ky B, Rhim A, Rustgi A, Courneya KS, Schmitz K, Endocrine Related Cancer, 1/1/2017
• Baseline Immunoglobulin E Levels as a Marker of Doxorubicin- and Trastuzumab-Associated Cardiac Dysfunction  
  Beer LA, Kossenkov AV, Liu Q, Luning PE, Domchek S, Speicher DW, Ky B, Circulation Research, 1/1/2016
• Cancer Therapy-Related Cardiac Dysfunction and Heart Failure: Part 1: Definitions, Pathophysiology, Risk Factors, and Imaging  
  Bloom MW, Hamo CE, Cardinale D, Ky B, Nohria A, Baer L, Skopicki H, Lenihan DJ, Gheorghiade M, Lyon AR, Butler J, Heart Failure Circulation, 1/1/2016
• Cancer Therapy-Related Cardiac Dysfunction and Heart Failure: Part 2: Prevention, Treatment, Guidelines, and Future Directions  
  Hamo CE, Bloom MW, Cardinale D, Ky B, Nohria A, Baer L, Skopicki H, Lenihan DJ, Gheorghiade M, Lyon AR, Butler J, Circulation Heart Failure, 1/1/2016
• Noninvasive Measures of Ventricular-Arterial Coupling and Circumferential Strain Predict Cancer Therapeutics-Related Cardiac Dysfunction  
  Narayan HK, French B, Khan AM, Plappert T, Hyman D, Bajulaiye A, Domchek S, DeMichele A, Clark A, Matro J, Bradbury A, Fox K, Carver JR, Ky B, JACC Cardiovascular Imaging, 1/1/2016
• The Associations between Peripheral Artery Disease and Physical Outcome Measures in Men and Women with Chronic Kidney Disease  
  Wang GJ, Shaw PA, Townsend RR, Anderson AH, Xie D, Wang X, Nessel LC, Mohler ER, Sozio SM, Jaar BG, Chen J, Wright J, Taliercio JJ, Ojo A, Ricardo AC, Lustigova E, Fai..., Annals of Vascular Surgery, 1/1/2016
• Prognostic value of galectin-3 for adverse outcomes in chronic heart failure  
  French B, Wang L, Ky B, Fang JC, Sweitzer NK, Cappola TP, Journal of Cardiac Failure, 1/1/2016
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Books/Book Chapters

• Braunwald's Heart Disease 
  Chapter: Cardio-Oncology 
  Ky BEditors: Zipes DP, Libby P, Bonow RO, Mann DL, Tomaselli GF.Edition 11th,2017
• Abeloff's Clinical Oncology 
  Chapter: Cardiovascular Effects of Cancer Therapy 
  Minasian L, Davis M, Ky BEdition 6th,2017

Abstracts/Posters

• Feasibility of an Electronic Implementation Method of an Evidence Based Exercise Intervention among Testicular Cancer Survivors (TCS).
  Fung C, Peckham J, Porto M, Lin P, Sahasrabudhe D, Guancial E, Ky B, Storozynsky E, Heckler C, Bruckner L, Mohile S, Mustian K, ASCO Survivor Symposium, San Diego, CA, 1/1/2017
• Cardiac Dysfunction is present at time of diagnosis of preeclampsia and persists postpartum.
  Levine LD, Downes KL, Arany Z, Ky B, Elovitz MA, Annual Meeting of the Society of Maternal Fetal Medicine, 1/1/2017
• Evolving Cardio-Oncology Study Designs.
  Minasian L, Dimond E, Shelburne N, Desvigne-Nickens P, Davis M, Adhikari B, Fagerstrom R, Fabian C, FLoyd J, Unger J, DOuglas PS, Mustian KM, Chow EJ, Lipshultz S, Hun..., Global Cardio-Oncology Summit, 1/1/2017
• Prospective Study of Cardiac Events during Proteasome Inhibitor Therapy for Relapsed Multiple Myeloma.
  Minasian L, Dimond E, Shelburne N, Desvigne-Nickens P, Davis M, Adhikari B, Fagerstrom R, Fabian C, FLoyd J, Unger J, DOuglas PS, Mustian KM, Chow EJ, Lipshultz S, Hun..., American Society of Hematology, 1/1/2017
• Challenges of Using Isobaric Labeling for In-depth Analysis of Large Numbers of Plasma Samples in a Cardiotoxicity Biomarker Discovery Study.
  Liu P, Beer L, Ky B, Speicher DW, American Society for Mass Spectrometry, 64th ASMS Conference, San Antonio, TX, 1/1/2016
• Assessing Sunitinib Cardiotoxicity using Engineered Cardiac Microtissues.
  Truitt R, Ky B, Margulies KB, Basic Cardiovascular Sciences Scientific Sessions- American Heart Association, Phoenix, AZ, 1/1/2016
• Early Changes in Biomarkers of Nitrosative Stress are Associated with Doxorubicin and Trastuzumab-Induced Cardiac Dysfunction in Breast Cancer Patients.
  Wang T, Finkelman B, Putt M, Wang L,Narayan H, Domchek S, DeMichele A, Narayan V, Carver JC, Tang W, Ky B, Global Cardio-Oncology Summit, Vancouver, CA, 1/1/2016
• Abnormalities in Three-Dimensional Left Ventricular Mechanics Early after Anthracycline Therapy are Associated with Subsequent Systolic Dysfunction
  Zhang KW, Finkelman BS, Gulati G, Narayan HK, Narayan V, Plappert T, Smith AM, Zhang C, French B, Ky B, 4th Annual MD Anderson Cancer and the Heart, Houston, TX, 1/1/2016
• Longitudinal Changes in Multiple Biomarkers Are Associated with Cardiotoxicity in Breast Cancer Patients Treated with Doxorubicin, Taxanes, and Trastuzumab.
  Hahn VS, Putt M, Januzzi J, Sawaya H, Sebag I, Planas J, Cohen V, Blanch J, Carver JR, Martin RP, Picard M, Gerstzen R, Halpern E, Passeri J, Kuter I, Scherrer-Crosbie..., American College of Cardiology Annual Meeting, 1/1/2015
• Diastolic Dysfunction Increases the Risk of Primary Graft Dysfunction after Lung Transplantation.
  Porteous MK, Ky B, Fitzpatrick JN, Plappert T, Diamond JM, Shah RJ, Brown M, Christie JD, and Kawut SM, International Society for Heart and Lung Transplantation, 1/1/2015
• Three Dimensional Ejection Fraction is More Strongly Determined by Strain than by Torsion in a Cohort of Breast Cancer Patients Undergoing Anthracycline-Based Chemothe...
  Gulati G, French B, Zhang KW, Narayan HK, Bajulaiye A, Zhang C, Hyman D, Ky B, American Heart Association, 1/1/2015
• Sex Differences in the Incidence of Peripheral Artery Disease (PAD) in the Chronic Renal Insufficiency Cohort (CRIC).
  Wang GJ, Shaw PA, Townsend RR, Anderson AH, Xie D, Nessel LC, Mohler III ER, Sozio SM, Jaar BG, Chen J, Wright J, Taliercio JJ, Ojo A, Ricardo AC, Lustigiva E, Fairman..., American Heart Association, 1/1/2015
• Measures of Three-dimensional Left Ventricular Mechanics Deteriorate Acutely after Cardiotoxic Cancer Therapy.
  Zhang KW, French B, Gulati G, Narayan HK, Bajulaiye A, Zhang C, Hyman D, Ky B, American Heart Association, 1/1/2015
• Biomarker Predictors of Recurrent Cardiac Hospitalization in Chronic Heart Failure.
  Vorovich E, French B, Ky B, Fang JC, Sweitzer NK, Cappola TP, American College of Cardiology Scientific Session, Washington, DC, 1/1/2014
• Clinical Risk Prediction in Antracycline Cardiotoxicity.
  Ky B, Warneke CL, Lenihan JL, Cheema PS, Moore DF Jr, Campbell MG, Yeshwant C, Adams PT, Krone R, Carver JR, Nasta S, Svoboda J, Schuster SJ, Reddy NM, Patel S, Rieber..., American Society of Clinical Oncology Annual Meeting, 1/1/2014
• Prediction and Early Detection of Anthracycline Related Cardiotoxicity Using Cardiac Biomarkers.
  Stevens PL, Lenihan DJ, Ky B, Wernecke C, Johnson M, Abramson V, Mayer I, Carver JR, Adams PT, Campbell MG, Cheema PS, Moore Jr DF, Yeshwant C, Fisch M, American Society of Clinical Oncology Annual Meeting, 1/1/2014
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Lectures

• Highlighted Original Research: Heart Failure and Cardiomyopathies and the Year in Review 
  2019 ACC Scientific Session & Expo, New Orleans - 3/18/2019
• Cardio-Oncology Case Challenges: Discussion with the Experts 
  2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
• Featured Clinical Research I 
  2019 ACC Scientific Session & Expo, New Orleans - 3/16/2019
• Breast Cancer & Cardio-Oncology 
  Washington, DC - 1/1/2017
• Cancer Therapy Cardiotoxicity: Mechanistic Risk Prediction 
  San Diego, CA - 1/1/2017
• How I Use Echocardiography in Cardio-Oncology 
  Philadelphia Cardiovascular Institute, Philadelphia, PA - 1/1/2017
• Biomarkers in Cardio-Oncology 
  Beijing, China - 1/1/2017
• How Do I Use Echocardiography in Cardio-Oncology 
  Beijing, China - 1/1/2017
• The Emerging Field of Cardio-Oncology 
  Beijing, China - 1/1/2017
• The Epidemiology and Clinical Assessment of Cancer Therapy Related Cardiac Dysfunction 
  San Diego, CA - 1/1/2017
• Know When to Hold 'em: Drugs to Avoid or Use Cautiously in Heart Failure: Oncology Drugs 
  Dallas, TX - 1/1/2017
• Cardiovascular Imaging Endpoints in Oncology Clinical Trials 
  Silver Spring, MD - 1/1/2017
• Cancer Therapy Cardiotoxicity: Use of Imaging and Biomarkers for Risk Prediction 
  1/1/2017
• Cardio-Oncology: Current Approaches to the Cardiovascular Care of Your Cancer Patient 
  Philadelphia, PA - 1/1/2017
• Biomarkers in Heart Failure with Recovered Ejection Fraction 
  Anaheim, CA - 1/1/2017
• The Evolving Landscape of Cancer Therapy Cardiotoxicity 
  Philadelphia, PA - 1/1/2017
• Mechanistic Risk Prediction 
  Philadelphia, PA - 1/1/2017
• Crystal Ball or Shattered Glass? Screening and Predicting Cancer Therapy Induced Cardiomyopathy 
  Anaheim, CA - 1/1/2017
• Cancer Therapy Cardiotoxicity: What Mechanisms are at Play? 
  Anaheim, CA - 1/1/2017
• Imaging Modalities to Diagnose Cardiovascular Toxicities 
  Silver Spring, MD - 1/1/2017
• Cardio-oncology 
  1/1/2017
• Predicting and Preventing Cardiomyopathy in Patients with Cancer 
  New Orleans, LA - 1/1/2016
• Improving Cancer Patient Care: Trade-offs between Efficacy and Toxicity 
  Washington, DC - 1/1/2016
• Imaging in Chemotherapy Induced Cardiotoxicity 
  Chicago, IL - 1/1/2016
• Early Identification of Subclinical Cardiac Toxicity - The Role of Biomarkers and Non-Invasive Imaging 
  New York, NY - 1/1/2016
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Other

• Cardiovascular Effects of Cancer Therapy in Long-term Cancer Survivors. 
  Ky B, Lenihan DJ, Uptodate
  1/1/2013