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Office
1515 Holcombe Blvd
Houston, TX 77030Phone+1 713-792-6161
Summary
- My clinical practice is centered on the management of patients with lower gastrointestinal malignancies, specifically colorectal & anal cancer. Translational research efforts are focused on identifying novel targets coupled with innovative clinical trial design for the treatment of rare and aggressive molecular subtypes of metastatic colorectal cancer such as atypical, non-V600 BRAF mutations and CMS4. Additional work is focused on elucidating the distinct tumor biology of patients with young onset colorectal cancer to more appropriately tailor therapy and clinical trial design for this unique group of patients. Finally, work is ongoing to incorporate & validate PET image analysis as a potential predictive marker of response and survival outcomes in the treatment of anal cancer patients.
Education & Training
- Mayo Clinic College of Medicine and ScienceFellowship, Advanced Oncology Fellowship - Gastroinestinal Malignancies, 2016
- University of TennesseeFellowship, Hematology and Medical Oncology, 2013 - 2016
- Geisinger Health System (Danville)Residency, Internal Medicine, 2010 - 2013
- Philadelphia College of Osteopathic MedicineClass of 2010
- Villanova UniversityB.S., Biology, Chemistry Minor, Ethics Concentration in Healthcare, 2001 - 2005
- Villanova UniversityB.S., Major in Biology, Minor in Chemistry, Ethics concentration in Health care, Cum Laude, 2001 - 2005
Certifications & Licensure
- FL State License 2021 - Present
- GA State License 2022 - 2025
- TN State License 2022 - 2025
- TX State License 2017 - 2025
- MS State License 2022 - 2024
- AL State License 2022 - 2023
- LA State License 2022 - 2023
- American Board of Internal Medicine Internal Medicine
- American Board of Internal Medicine Medical Oncology
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Awards, Honors, & Recognition
- Vail Workshop Participant: Methods in Clinical Cancer Research ASCO/AACR, 2018
- Fellow of the Year Award University of Tennessee Health Science Center, 2016
- Cancer Center Trainee Research Award West Cancer Center/UTHSC, 2016
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Clinical Trials
- Nivolumab After Combined Modality Therapy in Treating Patients With High Risk Stage II-IIIB Anal Cancer Start of enrollment: 2018 Jul 05
Publications & Presentations
PubMed
- 1 citationsMolecular, Socioeconomic, and Clinical Factors Affecting Racial and Ethnic Disparities in Colorectal Cancer Survival.Mahmoud Yousef, Abdelrahman Yousef, Saikat Chowdhury, Mohammad M Fanaeian, Mark Knafl
JAMA Oncology. 2024-11-01 - 14 citationsA shared neoantigen vaccine combined with immune checkpoint blockade for advanced metastatic solid tumors: phase 1 trial interim results.Amy R Rappaport, Chrisann Kyi, Monica Lane, Meghan G Hart, Melissa L Johnson
Nature Medicine. 2024-04-01 - Comprehensive Landscape of BRAF Variant Classes, Clonalities, and Co-Mutations in Metastatic Colorectal Cancer Using ctDNA Profiling.Benny Johnson, Van Morris, Xuemei Wang, Arvind Dasari, Kanwal Raghav
Cancers. 2024-02-09
Journal Articles
- Atypical, Non-V600 BRAF Mutations as a Potential Mechanism of Resistance to EGFR Inhibition in Metastatic Colorectal CancerBenny Johnson, Jonathan M. Loree, Alexandre A. Jacome, Shehara Mendis, Muddassir Syed, Van K. Morris II, Christine M. Parseghian, Arvind Dasari, Shubham Pant, Victoria..., JCO Precision Oncology 2019 :3, 1-10, 8/5/2019
- Co-morbidities Drive Outcomes for Both Malignancy-Associated and Non-Malignancy-Associated Hemophagocytic SyndromeJohnson, B., Giri, S., Nunnery, S., Wiedower, E., Jamy, O., Yaghmour, G., Chandler, J., Martin, M., Clinical Lymphoma Myeloma & Leukemia, 1/1/2016
- Emerging Role and Targeting of Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) in Human MalignanciesJohnson, B. and Mahadevan D., Clinical Cancer Drugs, 1/1/2015
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Abstracts/Posters
- Novel mutational and pathway signatures in relapsed/refractory colorectal cancer patientsJohnson, B., Cooke, L., Mahadevan, D, GI Cancers Symposium; Poster Session C: Cancers of the Colon, Rectum, and Anus, San Francisco, CA, 1/21/2016
- Novel mutational profiles in relapsed/refractory advanced cancer patients’ pre- and post-targeted therapyMahadevan, D., Johnson, N., Johnson, B., Pandey, P., Chandler, J., Cooke, L., 25th Annual Mayo Clinic Hematology/Oncology Reviews, The Ritz-Carlton, Amelia Island, FL, 1/1/2015
- Comorbidities Drive Outcomes for both Malignancy and Non-Malignancy Associated Hemophagocytic SyndromeJohnson, B., Giri S., Nunnery S., Wiedower E., Jamy O., Chandler J., Martin MG., ASH Meetings on Hematologic Malignancies; 57th ASH Annual Meeting and Exposition, Chicago, IL, 2015; Orlando, FL, 2015, 1/1/2015
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Press Mentions
- Fake News: CBS AGAIN Airs Footage of Italy Hospital in Report About “Overwhelmed” Penn. HospitalApril 9th, 2020
- ‘Irresponsible’: CBS Slammed for Using Coronavirus Footage from Italian Hospital to Portray NYCMarch 30th, 2020
- CBS News Uses Footage of “Worst Hit” Hospital in Italy While Describing New York Coronavirus OutbreakMarch 30th, 2020
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