Benjamin Levine Ebert MD

PubMed

• The Prolonged Half-Life of the p53 Missense Variant R248Q Promotes Accumulation and Heterotetramer Formation with Wildtype p53 to Exert the Dominant-Negative Effect.
  Nancy Klemm, Roman R Schimmer, Nils K Konrad, Flavian Thelen, Jonas Fullin
  Cancer Research. 2025-03-31
• Particle uptake by macrophages triggers bifurcated transcriptional pathways that differentially regulate inflammation and lysosomal gene expression.
  Isidoro Cobo, Jessica Murillo-Saich, Mohnish Alishala, Stephen Calderon, Roxana Coras
  Immunity. 2025-03-20
• 3 citations
  Exploration of the tunability of BRD4 degradation by DCAF16 trans-labelling covalent glues.
  Muhammad Murtaza Hassan, Yen-Der Li, Michelle W Ma, Mingxing Teng, Woong Sub Byun
  European Journal of Medicinal Chemistry. 2024-12-05

Journal Articles

• The Clinical Challenge of Clonal Hematopoiesis, a Newly Recognized Cardiovascular Risk Factor  
  Robert Sidlow, Amy E Lin, David P Steensma, Benjamin L Ebert, JAMA Cardiology
• Defining the Human C2H2 Zinc Finger Degrome Targeted by Thalidomide Analogs Through CRBN  
  Benjamin Ebert, MD, Science Magazine
• CrbnI391V Is Sufficient to Confer in Vivo Sensitivity to Thalidomide and Its Derivatives in Mice  
  Benjamin L Ebert, Emma C Fink, Blood
• PPM1D Truncating Mutations Confer Resistance to Chemotherapy and Sensitivity to PPM1D Inhibition in Hematopoietic Cells  
  Peter G Miller, Brenton Mar, Benjamin L Ebert, Shaunt Fereshetian, Anthony Letai, Siddhartha Jaiswal, Blood
• Join now to see all

Abstracts/Posters

• Deconstructing the Clonal Advantage and Clonal Stability of 5q- Candidate Genes in Del(5q) MDS on a Single Cell Level
  Benjamin L. Ebert, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• High Burden of Clonal Hematopoiesis in First Responders Exposed to the World Trade Center Disaster
  Benjamin L. Ebert, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• TP53 State Dictates Genome Stability, Clinical Presentation and Outcomes in Myelodysplastic Syndromes
  Benjamin L. Ebert, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Oncogenic Mechanisms of CBL E3 Ubiquitin Ligase Mutations in Myeloid Malignancies
  Benjamin L. Ebert, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Clonal Cytopenias of Undetermined Significance Are Common in Cytopenic Adults Evaluated for MDS in the National MDS Study
  Benjamin Ebert, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Exploiting the Zinc Finger Degrome Targeted By Lenalidomide to Engineer Reversible Off-Switch Degradable Chimeric Antigen Receptors
  Benjamin L. Ebert, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Systematic Characterization of Genes Representing Preferential Molecular Vulnerabilities for Myeloma Cells Compared to Other Neoplasias _ Implications for the Biology ...
  Benjamin Ebert, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Talazoparib Treatment Preferentially Depletes Cohesin-Mutant Clones in New In Vivo Models of Cohesin-Mutant Myeloid Diseases
  Benjamin Ebert, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/9/2019
• Functional Characterization of E3 Ligases and Their Regulators: Therapeutic Implications for Development of New Proteolysis-Targeting Chimeric Degraders of Oncoproteins
  Benjamin L. Ebert, 61st Annual American Society of Hematology Meeting, Orlando, FL, 12/7/2019
• Join now to see all

Lectures

• When You Least Expect It: Clonal Hematopoiesis as an Incidental Finding 
  ASCO Annual Meeting 2019 - Chicago, IL - 6/1/2019
• Friday Scientific Workshop on Myeloid Development 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Optimizing Clinical Outcomes in Blood Cancers Through Groundbreaking Translational Research 
  61st Annual American Society of Hematology Meeting - Orlando, FL - 12/7/2019
• Friday Scientific Workshop on Myeloid Development: Myeloid Malignancies 
  60th American Society of Hematology Annual Meeting - 11/30/2018
• Join now to see all